Clinical trials: Intervention Effectiveness
Mild Cognitive Impairment (MCI)
AI-Supported Cognitive Rehabilitation for Older Adults With Mild Cognitive Impairment
Mild cognitive impairment (MCI) is associated with increased risk of progression to dementia, highlighting the need for accessible interventions to support cognitive health.
- Trial name
- ReMind-AI (NCT07474038)
- Testing
- AI-Supported Cognitive Rehabilitation
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Kaiser Permanente
Plaque Psoriasis
Efficacy and Safety of Tildrakizumab 100 Milligrams (mg) in Participants With Moderate-Severe Chronic Plaque Psoriasis and Its Impact on Their Quality of Life (TRIBUTE)
The main aim of the study is to evaluate the efficacy, safety and impact on the health-related quality of life (HRQoL) in participants with moderate-to-severe chronic plaque psoriasis who are treated with tildrakizumab 100…
- Trial name
- TRIBUTE (NCT04229836)
- Testing
- Tildrakizumab 100 mg Solution for Injection
- Where
- 39 sites in Italy, Spain
- Volunteers
- 178 people
- Sponsor
- Almirall, S.A.
Fear of Childbirth, Haptonomy
The Effect of Mindfulness-Based Intervention and Haptonomy Application on Birth Self-Efficacy, Prenatal Attachment and Anxiety Levels of Pregnant Women With Fear of ChildBirth
Fear of childbirth is a common condition encountered during pregnancy. Women with fear of childbirth have reduced birth self-efficacy, and it leads to mental health problems in the prenatal and postnatal periods, reducing…
- Conditions
- Fear of Childbirth, Haptonomy, Mindfulness, Self-Efficacy
- Trial name
- NCT06956898
- Testing
- Mindfulness Training, Haptonomy Training
- Volunteers
- 225 people
- Sponsor
- Bayburt University
Sleep Disturbances
Effects of Brainwave Audio on Sleep in People With Sleep Disturbances
This exploratory study examines changes in sleep patterns during a four-week auditory stimulation intervention in 30 adults with self-reported sleep difficulties.
- Trial name
- NCT07909187
- Testing
- Brainwave Audio
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Kaohsiung Armed Forces General Hospital
Depression, Anxiety, Suicide
Mental Health in Primary Care
The goal of this study is to evaluate in an effectiveness-implementation type I hybrid trial, an enhanced version of eHealth Familias Unidas for reducing depressive, anxious symptoms and suicide behavior in Hispanic youth.
- Conditions
- Depression, Anxiety, Suicide, Drug Use
- Trial name
- NCT05426057
- Testing
- eHealth Familias Unidas Mental Health
- Where
- 17 sites in United States
- Volunteers
- 468 people, healthy volunteers welcome
- Sponsor
- University of Miami
Coronary Artery Disease, Drug-eluting Stent
Efficacy of Angiolite Stent vs a Second-generation Drug-eluting Stent Xience for Percutaneous Coronary Intervention
Clinical trial with an "European Community marked" medical device in patients with ischemic heart disease and clinical indication of coronary revascularization with drug-eluting stent.
- Trial name
- NCT03049657
- Testing
- Angiolite, Xience
- Where
- 11 sites in Spain
- Volunteers
- 220 people
- Sponsor
- Cardiva2 S.L.
Aged, Experiential Learning
Community Beauty and Health Program for Older Adults: An Experiential Learning Trial
This study develops and evaluates a "Senior Beauty and Health Care" course designed to improve students' awareness, attitudes, and skills in caring for older adults' appearance and well-being.
- Conditions
- Aged, Experiential Learning, Health Education
- Trial name
- NCT07053592
- Testing
- Geriatric Ｂeauty and Ｈealth Care Learning Program
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung University of Science and Technology
Pain
Comparison of the Efficacy of Oral Sucrose Administration at Two Different Times of a Painful Procedure in Neonates.
The objective of this study is to compare the use of 24% sucrose in pain control in neonates from 32 weeks of gestation onwards according to the time of administration of sucrose in venous and arterial puncture for blood…
- Trial name
- NCT05323071
- Testing
- Sucrose 24%
- Where
- Spain
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Oihana Lopez Alonso
Congenital Bleeding Disorder, Haemophilia B
Efficacy and Safety of NNC-0156-0000-0009 During Surgical Procedures in Subjects With Haemophilia B
This trial is conducted in Africa, Asia, Europe and the United States of America (USA). The aim of the trial is to evaluate the safety and efficacy of NNC-0156-0000-0009 (nonacog beta pegol) during surgical procedures in patients…
- Trial name
- paradigm™ 3 (NCT01386528)
- Testing
- nonacog beta pegol
- Where
- 41 sites in United States, Austria and 15 more
- Volunteers
- 13 people
- Sponsor
- Novo Nordisk A/S
Dyslexia
Intervention Efficacy of ALD for Children With Dyslexia
This double-blind, randomized controlled crossover trial aimed to evaluate the efficacy of providing assistive listening devices (ALDs) in improving specific abilities among Chinese children diagnosed with dyslexia.
- Trial name
- NCT07247253
- Testing
- Use of a real assistive listening device (FM system) in class.
- Where
- Hong Kong
- Volunteers
- 71 people
- Sponsor
- Education University of Hong Kong
Major Depressive Disorder
Brexpiprazole as Adjunctive Treatment in Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant Treatment
To evaluate the long-term efficacy and safety of brexpiprazole as an adjunctive treatment to an antidepressant treatment (ADT) for adult patients with Major Depressive Disorder (MDD).
- Trial name
- NCT01838681
- Testing
- Brexpiprazole, ADT
- Where
- 107 sites in United States, Bulgaria and 14 more
- Volunteers
- 1,986 people
- Sponsor
- H. Lundbeck A/S
Older Adults Without Any Specific Clinical Condition, Social Networks
A Study to Evaluate Community-Based Measures to Increase RSV Vaccine Use Among Latino Adults
In collaboration with community-based organizations, this study will focus on increasing RSV vaccine use among Latinos. The study will determine how effective community health worker counseling and text-message approaches are to…
- Conditions
- Older Adults Without Any Specific Clinical Condition, Social Networks, RSV Immunization, Vaccine Uptake
- Trial name
- NCT07171164
- Testing
- Motivate Aim: CHW text message reminders and counseling, Motivate Aim: CHW text message reminders only, Activate Aim: CHW text message reminders and counseling
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Primary Immune Thrombocytopenia
Safety and Efficacy Study of PF-06835375 in Primary Immune Thrombocytopenia
This is a Phase 2, open-label, multicenter, multiple subcutaneous injection, safety and efficacy study of PF-06835375 in adult participants with primary immune thrombocytopenia (ITP).
- Trial name
- NCT05070845
- Testing
- PF-06835375
- Where
- 24 sites in United States, Australia and 5 more
- Volunteers
- 61 people
- Sponsor
- Pfizer
S. Aureus Bloodstream Infection
Collect Clinical Data in Chinese Patients Received CUBICIN Treatment for Actual Usage in Clinical Practice
This is a Multicenter, observational, non-interventional registry designed to collect clinical data in Chinese patients who have received CUBICIN treatment under condition of actual usage in clinical practice.
- Trial name
- NCT01212601
- Where
- 18 sites in China
- Volunteers
- 203 people
- Sponsor
- AstraZeneca
Angina
Effectiveness of Ranolazine on Reducing Chest Pain in Patients With Blockage But no Stents
To determine if ranolazine improves angina symptoms at 4 months compared with placebo among patients who are deferred for receiving a Percutaneous Coronary Intervention (PCI) based on the Fractional Flow Reserve (FFR) measurement.
- Trial name
- IMWELL3 (NCT02147834)
- Testing
- Ranolazine, Sugar pill
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- North Florida Foundation for Research and Education
Colorektal Cancer
Self-Management of Colon and Rectal Cancer Patients Receiving Oral Chemotherapy
Objective: This study aims to evaluate the effectiveness of a message-based intervention on self-management among patients with colorectal cancer receiving oral chemotherapy treatment. H1.
- Trial name
- Self Managemet (NCT07851675)
- Testing
- Messaging Intervention Effectiveness, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ozlem
Hypertension
Embedded Community-based Heart-Age Risk Education Trial in Cinese Primary Healthcare
This study evaluates the effectiveness of a brief Heart Age-based risk education intervention embedded in routine primary care for older adults with hypertension in China.
- Trial name
- E-CHARM (NCT07045363)
- Testing
- Cognitive Intervention
- Where
- China
- Volunteers
- 358 people, healthy volunteers welcome
- Sponsor
- Duke Kunshan University
Insomnia
Effectiveness of a Guided Self-help Intervention for Improving Sleep in University Students
This randomized controlled trials aims to assess the effectiveness of an online guided self-help intervention ('i-Sleep \& BioClock') based on CBTi principles for university students' sleep problems.
- Trial name
- NCT06023693
- Testing
- i-Sleep & BioClock, Online Psychoeducation
- Where
- Netherlands
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Cerebral Palsy, Motor Disorders
Efficacy of INTORUS as a Therapeutic Tool in Motor Intervention in Patients at Aspace Centres in the Province of Cáceres
The goal of this Clinical Trial is to verify the effectiveness of the use of the Intorus device in the motor intervention in patients with cerebral palsy and related syndromes.
- Conditions
- Cerebral Palsy, Motor Disorders, Motor Activity
- Trial name
- NCT05753800
- Testing
- INTORUS
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Extremadura
Speech and Language Therapy
Parent-based Intervention for Language Delayed 2 to 3 Year Olds
The aim of the study is to evaluate the impact of parent based intervention on the language of 2 to 3 year old children from socially disadvantaged populations with a clinical diagnosis of primary language delay.
- Trial name
- NCT03083236
- Testing
- Standard PBI, Enhanced
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Solent NHS Trust
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