Clinical trials: Intervention Effectiveness
Depressive Symptoms
Nurse-Led Interprofessional Mental Health Promotion Intervention for Older Home Care Clients
Objective: The objective of this study is to evaluate the feasibility, acceptability and effectiveness of a 6-month nurse-led, interprofessional mental health promotion intervention aimed at older home care clients with…
- Trial name
- NCT01407926
- Testing
- Nurse-Led Mental Health Promotion Intervention
- Where
- Canada
- Volunteers
- 142 people
- Sponsor
- McMaster University
Parent-Child Relations, Parenting
Parental Support Intervention in the Oncological Context
Background: Cancer has a significant short and long-term impact on the family. Children of cancer patients may suffer from emotional, behavioral or somatic difficulties.
- Conditions
- Parent-Child Relations, Parenting, Communication Programs
- Trial name
- NCT03905278
- Testing
- Parental guidance
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aurore Liénard
Chronic Total Occlusion of Arteries of the Extremities
FastWire REvascularisation of Extremities, (For LOWer Limbs) - Feasibility Study (FREEFLOW)
This study is to assess the safety and efficacy of the FastWire System. It is intended to assess that the FastWire System can facilitate the intra-luminal placement of conventional guidewires or treatment devices beyond…
- Trial name
- NCT05869435
- Testing
- FastWire System Device - Peripheral
- Where
- Dominican Republic
- Volunteers
- 8 people
- Sponsor
- Versono Medical Ltd
COPD
NEXThaleR Real-world Study Assessing the EffectivenesS of BDP/FF/G Fixed triPle cOmbiNation on Symptom scorEs in COPD Patients
The goal of this observational study is to measure improvement in health related quality of life in moderate to severe COPD patients treated with Trimbow inhalation powder.
- Trial name
- RESPONSE (NCT05743608)
- Where
- 39 sites in Hungary
- Volunteers
- 1,336 people
- Sponsor
- Chiesi Hungary Ltd.
Self Injurious Behavior, Self Injurious Behavior Without Suicidal Intent
Examining the Effectiveness of a Brief Therapeutic Intervention for Reducing Self-Harm Among Adolescents
Non-suicidal self-injury (NSSI), defined as deliberate self-inflicted destruction of body tissue without intent to die, is particularly prevalent during mid-adolescence, with prevalence estimated around 16-22% in community…
- Trial name
- NCT07913425
- Testing
- Cutting Down Program - a three-month cognitive-behavioral psychotherapy focused on reducing self-injury urges and behaviors in adolescents
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- University of Haifa
Acute Coronary Syndrome
Pharmacodynamic Study on Efficacy of Clopidogrel With St. John's Wort
The purpose of this study is to evaluate whether patients post PCI receiving clopidogrel who are carriers of at least one CYP 2C19 loss-of-function allele may achieve improved pharmacodynamic efficacy of clopidogrel when treated…
- Trial name
- INDUCE-it (NCT01330589)
- Testing
- St. Johns Wort
- Where
- United States
- Sponsor
- Lancaster General Hospital
Congenital Bleeding Disorder, Congenital FVII Deficiency
Observational Study on the Efficacy and Safety of NovoSeven® During "Real-life" Usage in Germany
This NON INTERVENTIONAL OBSERVATIONAL STUDY is conducted in Europe. The primary aim is to observe the haemostatic efficacy of NovoSeven® treatment during routine practice in German clinics.
- Conditions
- Congenital Bleeding Disorder, Congenital FVII Deficiency, Glanzmann's Disease, Acquired Bleeding Disorder
- Trial name
- WIRK (NCT00697320)
- Testing
- eptacog alfa (activated)
- Where
- Germany
- Volunteers
- 64 people
- Sponsor
- Novo Nordisk A/S
Autism Spectrum Disorder
Online Parent-Mediated Intervention for Preschool Autistic Children
Autism spectrum disorder (ASD) is characterized by persistent deficits in social communication and interaction, accompanied by restricted and repetitive patterns of behavior.
- Trial name
- OYNA-1 (NCT07742774)
- Testing
- OYNA-1: Online Group-Based Parent-Mediated Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Herguner Therapy Private Clinic
Shame
Decrease Trauma-related Shame With Virtual Reality: The Effectiveness of SHINE-VR
Suffering from PTSD in childhood can have detrimental formative consequences. Researchers have been eager to develop effective interventions and to enhance treatment motivation since the introduction of the diagnosis of PTSD in…
- Trial name
- SHINE-VR (NCT06384508)
- Testing
- SHINE-VR
- Where
- 5 sites in Netherlands
- Volunteers
- 6 people
- Sponsor
- Universiteit Leiden
Hepatocellular Carcinoma
Non-Interventional Registry Study to Evaluate the Effectiveness of TheraSphere® in the Treatment of Hepatocellular Carcinoma (HCC)
The purpose of this registry study is to gather effectiveness, QoL, safety and procedural information on TheraSphere® for the treatment of participants with Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (iCC)…
- Trial name
- PROACTIF (NCT04069468)
- Testing
- TheraSphere
- Where
- 37 sites in France
- Volunteers
- 1,247 people
- Sponsor
- Boston Scientific Corporation
Infant Nutrition Disorders, Feeding Patterns
Effectiveness of a Dietary Counseling to Prevent Early Consumption of Added Sugar and Ultra-processed Foods
The purpose of the study is to prevent the early introduction of added sugar and ultra-processed foods and evaluate the impact on breastfeeding duration, complementary feeding quality, growth and prevalence of caries during the…
- Conditions
- Infant Nutrition Disorders, Feeding Patterns, Health Knowledge, Attitudes, Practice
- Trial name
- NCT03841123
- Testing
- Dietary Counseling
- Where
- Brazil
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- Federal University of Health Science of Porto Alegre
Glaucoma, Ocular Hypertension
This Follow-up Extension Study is Aimed to Monitor the Long-term IOP-lowering Performance/Efficacy and Safety of the MINT® Procedure in Open Angle Glaucoma Eyes.
This follow-up extension study is planned to invite all patients who underwent the MINT® surgery and completed Month 24 Visit in the prior MMS EEU-7 study.
- Conditions
- Glaucoma, Ocular Hypertension, Open-Angle Glaucoma
- Trial name
- NCT07081347
- Testing
- MINT Minimally Invasive Nasal Trabeculostomy
- Where
- Armenia
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Sanoculis Ltd
No Specific Conditions
Acceptance and Commitment Therapy for Informal Caregivers of People With Dementia
Dementia has a major impact on people with dementia and their family. Informal caregivers of people with dementia are at higher risk of developing depressive symptoms compared to informal caregivers of people with other chronic…
- Trial name
- ACT-IC (NCT05064969)
- Testing
- Blended intervention based in acceptance and commitment therapy
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Asthma Exacerbation, Quality of Life
Application of Telehealth Technology in Asthma Management
Background: While effective treatments are available, asthma control is sub-optimal for many asthma patients. To help patients self-manage their asthma symptoms, provision of an asthma action plan (AAP) in written format (wAAP)…
- Conditions
- Asthma Exacerbation, Quality of Life, Medication Adherence
- Trial name
- NCT05484037
- Testing
- CANATEXTS
- Where
- 3 sites in Canada
- Volunteers
- 620 people
- Sponsor
- University of British Columbia
Diabetes Mellitus, Hypertension
A Study to Evaluate the Efficacy and Safety of Dapagliflozin in Patient With Type 2 Diabetes Mellitus and Hypertension
The purpose of this clinical trial is to evaluate the efficacy and safety of dapagliflozin in patient with type 2 diabetes mellitus and hypertension
- Trial name
- NCT05970237
- Where
- South Korea
- Volunteers
- 9,000 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Stroke
Effectiveness of FACoT for Individuals Post Stroke
To develop and assess the effectiveness of a novel cognitive-functional intervention (FACoT) in occupational therapy for people after mild to moderate stroke.
- Trial name
- NCT02925637
- Testing
- FaCoT
- Where
- Israel
- Volunteers
- 66 people
- Sponsor
- Bait Balev Hospital
Malnutrition, Child, Wasting Disease
Cash Plus Interventions for Prevention of Acute Malnutrition in Children Under 5 and Their Mothers in Somalia
This trial studied different combinations of cash assistance to families that live in food insecure areas of Somalia and aimed to understand if this cash assistance provided reduced malnutrition of children and mothers.
- Conditions
- Malnutrition, Child, Wasting Disease, Stunting, Malnutrition
- Trial name
- NCT06642012
- Testing
- Cash only, Cash + Social Behavior Change Communication, Cash + top-up cash
- Where
- 2 sites in United States, Somalia
- Volunteers
- 3,384 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Hemophilia A
Safety and Efficacy Study of a Recombinant and Protein-Free Factor VIII (rAHF-PFM) in Hemophilia A Patients Undergoing Surgery
The purpose of this study is to evaluate whether rAHF-PFM is safe and effective in the treatment of hemophilia A patients undergoing surgery.
- Trial name
- NCT00157105
- Testing
- Antihemophilic factor, recombinant, manufactured protein-free
- Where
- 10 sites in United States
- Volunteers
- 59 people
- Sponsor
- Baxalta now part of Shire
Suicide, Suicide and Self-harm
Feasibility, Acceptability, and Preliminary Efficacy of a Novel Personalized Mobile Intervention for Suicide - Open Trial
The primary aim of this grant is to conduct pilot testing on a novel personalized mobile intervention for suicide - Mobile Application to Prevent Suicide (MAPS) - and to establish feasibility, acceptability, safety, and primary…
- Conditions
- Suicide, Suicide and Self-harm, Suicide, Attempted, Suicidal Ideation
- Trial name
- NCT05180331
- Testing
- Mobile Application to Prevent Suicide (MAPS)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Butler Hospital
Diabetes Mellitus Type 2
Effectiveness of Combining Patient Follow-Up With an Educational Intervention on Self-Management Skills of Type 2 Diabetes Mellitus Patients: A Controlled Intervention Study in Primary Care
The purpose of this clinical study is to evaluate whether patient education provided in conjunction with a structured, shared follow-up plan in primary care strengthens the self-management skills of patients with Type 2 Diabetes…
- Trial name
- NCT07783451
- Testing
- A structured shared follow-up plan combined with patient education
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Aysenur Aktemur
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