Clinical trials: Intervention Effectiveness
Smoking Cessation
Smoking Cessation and Relapse Prevention in Women Postpartum
Background: Pregnancy was found to be a significant triggering factor for smoking cessation and the reduction of nicotine consumption, but 50 - 70 % of mothers who stopped smoking during pregnancy resume tobacco smoking after…
- Trial name
- EARLINT-EP3 (NCT00475046)
- Testing
- Motivational Interviewing
- Volunteers
- 2,790 people
- Sponsor
- University Medicine Greifswald
Adolescent
A VR Intervention for Prosocial Behavior and Well-being Among Adolescents
The aim of this project is to examine the effectiveness of a gamified prosocial VR intervention.
- Trial name
- NCT06504069
- Testing
- Prosocial VR intervention
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Type 2 Diabetes Mellitus (T2DM), Obesity (Disorder)
Digital Dietary Intervention for Patients Receiving GLP-1 Receptor Agonist Therapy
The goal of this clinical trial is to learn whether adding the NutriSteppe digital dietary intervention to routine medical care improves metabolic health in adults aged 21 to 65 years with type 2 diabetes mellitus, obesity, or…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Obesity (Disorder), Overweight, Metabolic Syndrome
- Trial name
- NutriSteppe (NCT07728669)
- Testing
- NutriSteppe Digital Dietary Intervention
- Where
- Kazakhstan
- Volunteers
- 120 people
- Sponsor
- Kazakh Academy of Nutrition
Chronic Pain
Self-Management Interventions for Chronic Pain Relief With Cancer Survivors
Cancer survivors who suffer from chronic pain would benefit from a low-cost, self-management intervention they can use at home. This study will evaluate the efficacy of a recorded hypnosis intervention in reducing chronic pain…
- Trial name
- NCT03867760
- Testing
- Recorded Hypnosis Intervention, Recorded Relaxation Intervention
- Where
- 2 sites in United States
- Volunteers
- 109 people
- Sponsor
- University of Washington
Knowledge, Attitudes, Practice
Effectiveness of Metaverse-Based Immersive Technology Intervention for Oral Health Education: A Quasi-Experimental Study
To evaluate the effectiveness of pre- and post-intervention of oral health education using three interventions (conventional methods, mHealth, and the Metaverse platform) on the oral health status, knowledge, practices, and…
- Trial name
- NCT06543186
- Testing
- Oral health education lecture, Oral health education via mHealth on WhatsaApp, Oral health education via Metaverse platform on Meta-OHE
- Where
- 2 sites in Malaysia
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Universiti Teknologi Mara
PTSD, Physical Injury
IT Enhanced Peer Integrated Collaborative Care for US Trauma Care Systems
This study evaluates two readily implementable approaches to the delivery of transitional care for injured patients treated emergently in US trauma care systems.
- Trial name
- TSOS 7 Peer (NCT03569878)
- Testing
- Peer-Integrated Multidisciplinary Collaborative Care, Trauma surgery team notification
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- University of Washington
Healthy
Health4Life a Digital Intervention to Promote Healthy Lifestyle Behaviours From the Start of Life
The overall aim of this project is to evaluate the effectiveness and implementation of a digital intervention to support parents to create healthy lifestyle behaviours from the start of their infant's life, in order to prevent…
- Trial name
- Health4Life (NCT06798597)
- Testing
- Health4Life app
- Where
- Sweden
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Weight Loss
Cost Effectiveness of Nutrition Intervention in Long Term Care
Inadequate food and fluid intake is a common problem among nursing home (NH) residents and one that can lead to under-nutrition, dehydration, weight loss, hospitalization, and even death.
- Trial name
- NCT02567526
- Testing
- Between-Meal Intervention Group
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Hip Fracture, Disability
Efficacy of a Post-Rehabilitation Exercise Intervention
Background: Many people who have suffered a hip fracture are discharged from rehabilitation services with significant residual functional limitations and disability.
- Trial name
- NCT00592813
- Testing
- Enhanced Strong for Life, cardiovascular nutrition education
- Where
- United States
- Volunteers
- 232 people
- Sponsor
- Boston University
Medication Adherence, Adjustment Reaction With Anxiety and Depression
Mindfulness and Acceptance Based Therapy for Adolescents Living With HIV
Adolescents represent a growing share of people living with HIV in sub-Saharan Africa (SSA), yet show poor adherence to medication and viral suppression (VS) compared to adults.
- Conditions
- Medication Adherence, Adjustment Reaction With Anxiety and Depression, Mental Health Issue
- Trial name
- NCT05010317
- Testing
- Mindfulness and acceptance based therapy, Standard of care
- Where
- 2 sites in Uganda
- Volunteers
- 122 people
- Sponsor
- Infectious Diseases Research Collaboration, Uganda
Diabetes
Effectiveness of the Diabetes Conversation Map Program Among Diabetic Patients in Taiwan
The Diabetes Conversation Map Program (DCMP) is a novel, group-based, interactive diabetes management education program that has been shown to help patients adapt to their disease.
- Trial name
- NCT02733315
- Testing
- Diabetes Conversation Map Program
- Volunteers
- 95 people
- Sponsor
- Dalin Tzu Chi General Hospital
Cardiac Surgical Procedures
Buckberg vs Del Nido in Isolated Aortic Valve Replacement
The study compares safety and efficacy of the Del Nido cardioplegic solution, comparing it with the Buckberg cardioplegic solution in single aortic valve replacement procedures.
- Trial name
- NCT04259515
- Testing
- Del Nido, Buckberg
- Where
- 2 sites in Spain
- Volunteers
- 286 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Labor Pain, Analgesia, Obstetrical
Individualized Timing of Analgesia and Effectiveness of Labor Analgesia
Neuraxial analgesia is the gold standard to relieve labor pain. A recent "Practice guidelines for obstetric anesthesia" suggests that neuraxial analgesia should be provided in the early stage of labor (cervical dilation < 5 cm)…
- Conditions
- Labor Pain, Analgesia, Obstetrical, Early Medical Intervention
- Trial name
- NCT02920489
- Testing
- Individualized epidural analgesia, Routine epidural analgesia
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University First Hospital
Pelvic Venous Disorders, Pelvic Congestive Syndrome
The Efficacy and Safety of Interventions on the Pelvic Veins in Pelvic Venous Disorders
This study includes a retrospective and prospective study will enroll patients with pelvic venous disorders who have undergone pelvic vein surgery and endovascular interventions. Three groups of patients will be formed.
- Conditions
- Pelvic Venous Disorders, Pelvic Congestive Syndrome, May-Thurner Syndrome
- Trial name
- ESIPV (NCT05076448)
- Testing
- Gonadal veins resection, Gonadal vein embolization with coils, Endovascular stenting of the common iliac vein (CIV)
- Where
- Russia
- Volunteers
- 400 people
- Sponsor
- Pirogov Russian National Research Medical University
Physical Activity
Training Intervention in Heart Failure and Frail Elderly Population
There is enough scientific evidence of the benefits detection of frailty in patients with heart failure, which is an important prognostic factor.
- Trial name
- TIHFEP (NCT02365155)
- Testing
- Multicomponent training intervention., Nutrition intervention, Cognitive intervention
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Hospital de la Ribera
Asthma Childhood
Effectiveness of an Educational Intervention on Asthmatic Children in Inhaled Technique and Adherence.
The goal of this study is to see if a short educational session and demonstration by a nurse can help asthmatic children (6-17 years-old), under hospital control, to manage their asthma better, to use their inhaler correctly, and…
- Trial name
- NCT07364643
- Testing
- Educational Intervention
- Volunteers
- 428 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Hazardous Drinking, Harmful Drinking
Testing the Efficacy of an Online Alcohol Intervention in a Workplace Setting
The purpose of this study is to test - in a workplace setting - if an online multi-session alcohol intervention improves treatment effect over and above a single session screening with feedback.
- Trial name
- NCT01931618
- Testing
- Online screening and feedback, Online booklet., Online multi session follow-up
- Where
- Norway
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Autism Spectrum Disorder
Affective Prosody Recognition and Auditory Intervention for Children With Autism Spectrum Disorders (ASD)
The proposed study aims to examine the abilities of children with ASD to recognize emotional tones of voice - also known as affective prosody - as compared to typically developing (TD) children.
- Trial name
- NCT04427150
- Testing
- Auditory Training, Non-auditory training
- Where
- Hong Kong
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Illness Terminal
The Family Talk Intervention When a Parent With Dependent Children or a Child is Severely Ill
The overall aim of this study is to evaluate the effects and the implementation process of the Family Talk Intervention (FTI) in clinical practice when a child or a parent of dependent children has a…
- Trial name
- NCT05020158
- Testing
- Family Talk Intervention
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Ersta Sköndal University College
Severe Asthma
Real-world Study Assessing Efficacy of TezepeLumaB in Patients With Severe Asthma Regardless of Phenotype in Russia
ELBRUS is a 12-month (52-week), multi-centre, prospective, non-comparative and non-interventional (observational), post-reimbursement real-world evidence study that will assess patient-reported outcomes after tezepelumab…
- Trial name
- ELBRUS (NCT06566885)
- Where
- 15 sites in Russia
- Volunteers
- 125 people
- Sponsor
- AstraZeneca
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