Clinical trials: Intervention Effectiveness
ADHD
Hybrid Effectiveness-Implementation Trial of a School Clinician Training and Psychosocial ADHD/ODD Intervention Program Adapted for Schools Across Mexico
Neurodevelopmental disorders of Attention-Deficit/ Hyperactivity Disorder (ADHD) and Oppositional Defiant Disorder (ODD) are extremely common but underserved with Evidence- Based Treatments (EBT) worldwide.
- Trial name
- (CLS-A-FUERTE) (NCT06457256)
- Testing
- CLS-A-FUERTE
- Where
- 3 sites in United States, Mexico
- Volunteers
- 872 people
- Sponsor
- University of California, San Francisco
Atrial Fibrillation
Peer-Mentor Support for Vulnerable Patients With Atrial Fibrillation
The goal of this randomized clinical trial is to evaluate whether a peer-mentor intervention can improve mental well-being among vulnerable patients with atrial fibrillation (AF).
- Trial name
- EMPOWER-AF (NCT07498283)
- Testing
- Peer-Mentor Support
- Where
- 3 sites in Denmark
- Volunteers
- 290 people
- Sponsor
- University College Copenhagen
Heart Failure
Motivational Interviewing Tailored Intervention for Patients With Heart Failure (MITI-HF)
This study will test the effectiveness of motivational interviewing and skill building compared to usual care to improve self-care in heart failure (HF) patients.
- Trial name
- MITI-HF (NCT02177656)
- Testing
- Motivational Interviewing tailored intervention
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ruth Masterson-Creber
Swallowing Disorder, Oropharyngeal Dysphagia
Effectiveness of an Optimal-Massive Intervention in Older Patients With Dysphagia
The aim of this study is to evaluate the efficacy of an optimal-massive intervention (OMI) based on increasing shear viscosity of fluids, nutritional support with oral nutritional supplements (ONS) and triple adaptation of food…
- Conditions
- Swallowing Disorder, Oropharyngeal Dysphagia, Respiratory Infection, Malnutrition
- Trial name
- OMI (NCT04581486)
- Testing
- Optimal-Massive Intervention, Control (standard clinical practice)
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Hospital de Mataró
Oral Health Behavior Change
EHBM-Based Intervention on Collegians' Adherence to Oral Health Behaviors (EHBM- CAOHB)
This study aims to evaluation of collegians adherence to oral health behavers and to examine the efficacy of the Expanded Health Belief Model-based intervention in enhancing oral health behaviors among collegians.
- Trial name
- RCT (NCT07715773)
- Testing
- Intervention Group
- Where
- Iraq
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Patent Ductus Arteriosus
Post Marketing Clinical Follow Up Study to Evaluate Efficacy and Safety of the Occlutech PDA Occluder in Patients With Patent Ductus Arteriosus Defects
This retrospective and prospective, multicenter, international post marketing follow up study evaluates the safety and efficacy of the Occlutech® PDA Occluder, delivered using the Occlutech Occlusions Pusher (OOP), in subjects…
- Trial name
- NCT05264753
- Testing
- Occlutech® PDA Occluder
- Where
- 15 sites in Canada, France and 7 more
- Volunteers
- 255 people
- Sponsor
- Occlutech International AB
Asthma
Tele-spirometry in Primary Care - Randomized Clinical Trial Cluster: the Effectiveness of Telemedicine in Asthma
The purpose of this study is to determine the effectiveness of telemedicine multifaceted intervention in symptoms patients with asthma.
- Trial name
- RESPIRANET-A (NCT02901522)
- Testing
- telemonitoring, Spirometry (baseline), Spirometry (20 - 22weeks)
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Loneliness
Evaluating the Effectiveness of Interventions to Reduce Loneliness in Chinese Young Adults
This study aims to evaluate the effectiveness of a group-based Positive Affect (PA) intervention compared to an active control condition, Social Skills Training (SST), in reducing loneliness among young adults in Hong Kong and…
- Trial name
- NCT07543653
- Testing
- Group-based Positive Affect Intervention, Group-based Social Skills Training
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Education University of Hong Kong
Peri-implant Mucositis
Efficacy of Adjunctive At-Home Photodynamic Therapy (aPDT) in the Treatment of Peri-Implant Mucositis
The study aims to establish a validated protocol enabling an alternative approach for bacterial biofilm control through the application of a novel at-home photodynamic/antibacterial blue light therapy in addition to non-surgical…
- Trial name
- NCT06859866
- Testing
- Standard oral hygiene, The addition of home-based dual-light photodynamic therapy (Lumorinse® + Lumoral®)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Koite Health Oy
Knee Osteoarthritis
Observation of the Clinical Efficacy of Two Surgical Procedures for Varus Knee Osteoarthritis
The purpose of this study is to conduct a prospective randomized controlled trial to compare the effects between two surgical procedures in the treatment of varus knee osteoarthritis.The hypothesis was that there would be no…
- Trial name
- NCT05382429
- Testing
- OWHTO, CWHTO
- Where
- China
- Volunteers
- 160 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
A Canadian Study of the Effectiveness of Tresiba® (Insulin Degludec) After Switching Basal Insulin in a Population With Type 1 or Type 2 Diabetes Mellitus
The purpose of this study is to collect historical data in real life conditions in a large group of people who have type 1 or type 2 diabetes and were treated with Tresiba® (insulin degludec) for at least 6 months.
- Trial name
- CAN-TREAT (NCT03674866)
- Testing
- Insulin degludec
- Where
- 32 sites in Canada
- Volunteers
- 662 people
- Sponsor
- Novo Nordisk A/S
Functional Dyspepsia, Irritable Bowel Syndrome
The Efficacy and Safety of "BST104" (Lonicera Flos Extract) in Mild to Moderate Functional Dyspepsia Subjects
This study was conducted to prove the efficacy of BST-104 in patients with mild to moderate FD.
- Trial name
- NCT04008901
- Testing
- BST-104 (Lonicera Flos Extract)
- Where
- South Korea
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Bereavement, Grief
Effectiveness of a Standardized Bereavement Intervention in Primary Care
The purpose of this study is to evaluate the efficacy of "Primary Bereavement Care" (PBC) -a standardized bereavement intervention- delivered by family physicians (FP), in widows.
- Trial name
- NCT00133263
- Testing
- Primary Bereavement Care, the current bereavement care in primary care
- Where
- Spain
- Volunteers
- 87 people
- Sponsor
- Carlos III Health Institute
Emotional Distress
Exploring the Feasibility and Effectiveness of a MIED-Based Adolescent Mindfulness Intervention Group for Youth With Emotional Distress
Background: Adolescent emotional distress (anxiety and depressive symptoms) is rising globally. The detection rate of depression risk among Chinese middle and high school students reaches 24.6%, with anxiety risk at 18.1%.
- Trial name
- NCT07715916
- Testing
- MIED-based Adolescent Mindfulness Intervention Group
- Volunteers
- 40 people
- Sponsor
- Xinghua Liu
Other Conditions That May Be A Focus of Clinical Attention
Effectiveness of Buddhist Intergrated Group Intervention on Minefulness in Adolescents
The pupose of the study is to determine the effectiveness of the Buddhist integrated group intervention improve the mindfulness in adolescents by a randomized controlled trial.The study divede the adolescents in two groups group…
- Trial name
- NCT01605604
- Testing
- buddhist mind fullness
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Metabolic Disease
Effectiveness of Technology for Metabolic Diseases Combined Sarcopenia
The lifestyle program intervention program focusing on healthy dietary habit and exercise effectively prevents metabolic syndrome, sarcopenia or frailty.
- Trial name
- NCT05476536
- Testing
- self-management skills and healthy technology APP
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chang Gung University of Science and Technology
Skin Aging
Tolerance and Efficacy Evaluation of 3 Face Creams
The study will evaluate the tolerance and the efficacy on skin comfort of F#1048-082 soothing cream used just after injection procedure and also the tolerance and the efficacy of the F#841-020 anti-age cream on aging parameters…
- Trial name
- FILLER (NCT02063971)
- Testing
- Soothing (formulation number: F#1048-082) and antiaging creams (F#841-020 and F#1374-002)
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Adele Sparavigna
ALS - Amyotrophic Lateral Sclerosis
Atalante Exoskeleton in the Rehabilitation of Patients With Amyotrophic Lateral Sclerosis
Using a MRI gait motor imagery paradigm in ALS patients in order to study how ALS affects the function of the central neural networks involved in gait function, we showed a reorganization of the motor networks that represents a…
- Trial name
- EXALS (NCT06199284)
- Testing
- Atalante exoskeleton
- Where
- 3 sites in France
- Volunteers
- 20 people
- Sponsor
- Institut de Recherche sur la Moelle épinière et l'Encéphale
Prostate Cancer, Incontinence
Is the HIFEM Procedure an Effective Treatment for Men With Post-prostatectomy Incontinence?
Urinary incontinence after radical prostatectomy surgery is a common condition that negatively affects daily life. Patients often experience discomfort due to urine leakage and the resulting need to use pads daily.
- Conditions
- Prostate Cancer, Incontinence, Pelvic Floor Muscle Weakness
- Trial name
- HIFEM for PPI (NCT06372704)
- Testing
- HIFEM
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Obesity Prevention, Cancer Prevention
Effectiveness of the Croq'Santé Nutrition Education Program in Improving Food Literacy in Schoolchildren
Background: Nutritional factors including diet, physical activity, weight status and alcohol consumption are among the most important preventable risk factors for cancer.
- Trial name
- NCT06796244
- Testing
- Croq'Santé nutrition education program
- Where
- France
- Volunteers
- 1,205 people, healthy volunteers welcome
- Sponsor
- Marie HERR
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