Clinical trials: Intervention Effectiveness
Atopic Dermatitis
A Clinical Study to Assess the Safety and Effectiveness of Test Products in Mild to Moderate Atopic Dermatitis (AD) Patients.
This is an exploratory, proof-of-concept, double-blind, placebo-controlled, randomized, comparative, interventional, prospective, safety in-use tolerability and efficacy study of test products in patients with mild to moderate…
- Trial name
- NCT06687512
- Testing
- Treatment Cream
- Where
- India
- Volunteers
- 44 people
- Sponsor
- NovoBliss Research Pvt Ltd
Fibrocystic Breast Disease
Possibilities of Phytomedicine in Monotherapy of Benign Breast Diseases
The aim of this study is to evaluate the effectiveness of the use of the drug, containing Vitex agnus castus extract (VAC), in patients with fibrocystic breast disease .
- Trial name
- NCT05717894
- Testing
- Vitex Agnus Castus Extract
- Where
- Kazakhstan
- Volunteers
- 150 people
- Sponsor
- Nazgul Omarbayeva
Age-related Macular Degeneration
Laser Intervention in Early Age-Related Macular Degeneration Study
The purpose of this study is to determine whether 2RT nanosecond laser therapy slows the progression to advanced age-related macular degeneration.
- Trial name
- LEAD (NCT01790802)
- Testing
- 2RT nanosecond laser
- Where
- Australia
- Volunteers
- 292 people
- Sponsor
- Center for Eye Research Australia
Major Depressive Disorder
Vortioxetine Intravenous Infusion at Initiation of Oral Treatment With Vortioxetine in Patients With Depression
The purpose of this study is to evaluate the efficacy and safety of vortioxetine given as a single intravenous dose of 25 mg at initiation of an oral vortioxetine regimen of 10 mg/day for 7 days
- Trial name
- NCT03766867
- Testing
- Vortioxetine infusion 25 mg, Vortioxetine tablets 10 mg/day
- Where
- 13 sites in Bulgaria, Estonia and 1 more
- Volunteers
- 80 people
- Sponsor
- H. Lundbeck A/S
Delirium Confusional State
Exploring the Effectiveness of Intelligent Audiovisual Interventions in Delirium, Agitation, and Pain Among Middle Aged and Elderly Patients in Emergency Intensive Care Units: A Quasi-Experimental Study
The goal of this nonrandomized, quasi-experimental clinical trial is to evaluate whether an intelligent audiovisual intervention can prevent delirium and reduce delirium severity, agitation, and pain among adults aged 55 years or…
- Trial name
- NCT07776002
- Testing
- Intelligent Audiovisual Intervention
- Volunteers
- 128 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
HIV Seropositivity
Hybrid Type I Effectiveness-Implementation Trial of a Social Network Support Intervention
The goal of this Hybrid Type I effectiveness-implementation trial is to test an evidence-based, flexible, and tailored intervention that leverages existing social network members to promote retention in care and viral suppression…
- Trial name
- NCT05723653
- Testing
- Social Network Support Intervention
- Where
- 7 sites in United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Nurses, Resilience, Psychological
Effectiveness of Positive Psychological Intervention on Resilience Improvement in Nurses
The nursing profession, comprising over 27.9 million individuals and representing 59% of the health sector, plays a critical role in frontline healthcare globally.
- Conditions
- Nurses, Resilience, Psychological, Positive Psychology
- Trial name
- NCT06572202
- Testing
- Positive Psychology Intervention
- Where
- Indonesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Fitria Endah Janitra
Myopia
Efficacy and Safety of ReLEx Smile for Laser Correction of Myopia
Evaluation of the safety and efficacy of the Carl Zeiss Meditec VisuMax femtosecond laser for lamellar resection (ReLEx smile) in the reduction of myopia.
- Trial name
- NCT01481792
- Where
- Denmark
- Volunteers
- 125 people
- Sponsor
- University of Aarhus
Preoperative Care, Child
Reducing Anxiety of Children and Their Parents in the Pre-elective Surgery Process
It is emphasized in the studies that the child and parent anxiety that occurs in pediatric surgery should be prevented or reduced.
- Conditions
- Preoperative Care, Child, Parent, Anxiety
- Trial name
- NCT05538039
- Testing
- Distract with play dough, Distract with play kaleidoscope, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Isparta University of Applied Sciences
Obesity
"Efficacy in Adolescents of Continued Behavior Modification Following a Six Month Sibutramine-based Weight Management Intervention"
There are few studies that look at sustained weight loss in the adolescent population. This study uses a multidisciplinary approach along with pharmacotherapy (use of Meridia)to motivate and establish behavior changes in…
- Trial name
- AOS (NCT01023139)
- Testing
- Sibutramine
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Glaucoma, Trabeculectomy
Innovative Tube Trabeculectomy for Advanced and Refractory Glaucoma: A Randomized Controlled Trial
This study aims to compare the efficacy and safety of a novel surgical technique, Innovative Tube Trabeculectomy (ITT), against conventional trabeculectomy in patients with advanced and refractory glaucoma.
- Conditions
- Glaucoma, Trabeculectomy, Innovative Procedures
- Trial name
- ITT-RCT (NCT07755761)
- Testing
- Innovative Tube Trabeculectomy, Conventional Trabeculectomy
- Where
- Egypt
- Volunteers
- 116 people
- Sponsor
- Benha University
STEMI - ST Elevation Myocardial Infarction, Thrombosis Cardiac
Efficacy of Using 50 ml Syringe Manual Thrombectomy Catheter in Primary PCI With Heavy Thrombus Burden
In high thrombus burden subgroup of Acute STEMI, manual aspiration thrombectomy was associated with reduced cardiovascular death but increased stroke or transient ischemic attack.
- Trial name
- NCT06327659
- Testing
- 30 mL syringe manual thrombectomy catheter, 50 mL syringe manual thrombectomy catheter
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Helwan University
Autism Spectrum Disorder (ASD, Parental Behaviors
Effectiveness of Video-feedback for Positive Parenting with Children At Risk of ASD
Improving parent-child interactions benefits child development and parents' perception of their competencies for childrearing and support for child learning and development, which in turns positively impacts on parental emotional…
- Trial name
- VIFEPOPA (NCT06604988)
- Testing
- Video-feedback intervention to promote positive parenting
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Barcelona
Elderly
The Use of Virtual Reality for the Gait Training of Elderly Fallers
The study aims to investigate the efficacy of gait training using virtual reality to decrease the risk of falls in elderly idiopathic fallers.
- Trial name
- VR-Fallers (NCT01182961)
- Testing
- gait training, gait training 2, exercise group
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Venous Disease
Efficacy on Pain Following a Procedure for Injecting Sclerotherapeutic Foam Into the Great Saphenous Vein
The trial objectives are to compare efficacy relative to pain, along the route of the vein following echoguided endovenous injection of sclerotherapeutic foam into the Great Saphenous vein, of class III microfibre compression…
- Trial name
- NCT01368159
- Testing
- Compression Stockings
- Volunteers
- 120 people
- Sponsor
- Le Club Mousse
Auditory Hallucination
The Efficacy of Speech Competition Training on Auditory Hallucination in Schizophrenia
One hundred schizophrenia patients with auditory hallucinations will be recruited and randomized into group A and group B. Participants of group A will firstly receive a speech competition training for 2 weeks, and those in group…
- Trial name
- NCT05850923
- Testing
- speech competition training, the soothing music
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jing SHI
Alaska Native Youth Aged 14 - 24, Suicide, Attempted
Suicide Intervention for Alaska Native Youth
Two interventions will be delivered virtually to American Indian/Alaska Native youth who have been hospitalized with suicidal attempt, suicidal ideation, or associated risk behaviors, including alcohol-related injury.
- Conditions
- Alaska Native Youth Aged 14 - 24, Suicide, Attempted, Suicidal Ideation, Alcohol Intoxication
- Trial name
- BeWeL (NCT05360888)
- Testing
- Tools for Life, Tools for Life + MISN
- Where
- 2 sites in United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- RAND
Infertility
Efficacy of Embryo Transfer Procedure Guided by Transvaginal Ultrasound Versus Abdominal Ultrasound in Oocytes Recipients
The objective of this study is to evaluate the efficacy of embryo transfer procedure guided by transvaginal ultrasound versus abdominal ultrasound in recipients of oocytes as well as the advantages and disadvantages of the new…
- Trial name
- NCT01137461
- Testing
- ultrasound-guided embryo transfer
- Where
- Spain
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Fundació Privada Eugin
Stress, Psychological, Occupational, Burnout, Professional
Internet-Based Intervention for Occupational Stress Among Medical Professionals
The aim of this study is to assess the efficacy of internet intervention for reduction of occupational stress and its negative consequences (job burnout, depression) among medical professionals through the enhancement of the…
- Trial name
- Med-Stress (NCT03475290)
- Testing
- Personal resources' enhancement: self-efficacy and perceived social support, Personal resources' enhancement: perceived social support and self-efficacy, Personal resources' enhancement: self-efficacy
- Where
- Poland
- Volunteers
- 1,240 people, healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Influenza
Study to Evaluate the Effectiveness of FluMist Vaccination in a School-Based Intervention Program
To measure the effectiveness of influenza vaccination in school children by comparing, between target(i.e., children are offered FluMist) and control (i.e., children are not offered FluMist) school families.
- Trial name
- NCT00192218
- Testing
- FluMist
- Where
- 2 sites in United States
- Volunteers
- 3,022 people, healthy volunteers welcome
- Sponsor
- MedImmune LLC
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