Clinical trials: Intervention Effectiveness
Obesity, Overweight
A Regulatory Post-marketing Surveillance (rPMS) Study to Evaluate the Safety and Effectiveness of Saxenda®(Liraglutide 3.0 mg) in Obese Patients and Overweight Patients With Obesity-related Comorbidities in Routine Clinical Practice in Korea.
The purpose of this study is to collect information about the safety and effectiveness of Saxenda® in obese patients and overweight patients with obesity-related comorbidities.
- Trial name
- NCT03560336
- Testing
- Liraglutide
- Where
- 28 sites in South Korea
- Volunteers
- 758 people
- Sponsor
- Novo Nordisk A/S
Critical Limb Ischemia
Efficacy and Safety of Apixaban in Reducing Restenosis and Limb Loss in PAD Patients.
This study will evaluate the efficacy and safety of apixaban 2.5 mg twice daily plus aspirin compared to the standard treatment (clopidogrel plus aspirin) in patients with critical limb ischemia undergoing infrapopliteal arterial…
- Trial name
- AGRIPPA (NCT04229264)
- Testing
- Apixaban, ASA, Clopidogrel 75mg
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Science Valley Research Institute
Arthritis Knee
Effectiveness of Client-centered Intervention in After Total Knee Arthroplasty
The current study was conducted to comparison of the Client-centered (CC) intervention with face-to-face (FF) and TR methods after Total Knee Arthroplasty (TKA).
- Trial name
- NCT04969432
- Testing
- Client-centered
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Saglik Bilimleri Universitesi
Breastfeeding, Practice
Early Breastfeeding Cessation - is It Possible to Prevent?
The purpose of this study is to investigate if a postnatal public health breastfeeding intervention relying on the importance of the psychosocial factors can prolong the period with exclusive breastfeeding duration among mothers…
- Conditions
- Breastfeeding, Practice, Maternal Behaviour, Self-Efficacy
- Trial name
- NCT00145834
- Testing
- community based trial
- Where
- Denmark
- Volunteers
- 1,456 people
- Sponsor
- University of Aarhus
Intracranial Aneurysm, AVM - Cerebral Arteriovenous Malformation
Postmarket Study of Tarvos Microguidewire in Neurovascular Interventional Surgery
This investigation is to evaluate the clinical effectiveness and safety of the Tarvos Microguidewire in the neurovascular interventional surgery.
- Conditions
- Intracranial Aneurysm, AVM - Cerebral Arteriovenous Malformation, AV Fistula, Acute Ischemic Stroke
- Trial name
- NCT07500155
- Testing
- Tarvos Microguidewire
- Where
- China
- Volunteers
- 121 people
- Sponsor
- Keuro MedTech
Methamphetamine Addiction
Efficacy of Adaptive, Gamified Digital Therapeutics Intervention for Individuals With Methamphetamine Use Disorder in Community Rehabilitation
This study evaluates the efficacy of a comprehensive, adaptive digital therapeutics (DTx) smartphone application compared to treatment as usual (TAu) for individuals with Methamphetamine Use Disorder (MUD) receiving…
- Trial name
- NCT07319325
- Testing
- WonderLab Harbor+ (Adaptive DTx), Standard Community Counseling
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Adai Technology (Beijing) Co., Ltd.
Diabetic Foot Ulcer, Diabetic Neuropathy Peripheral
Patients With Diabetic Neuropathy Who Receive Physiotherapy Treatment Will Have a Decrease in Diabetic Foot Ulcers
This study evaluates the effects of a physiotherapy protocol (manual therapy and exercise) in the prevention of diabetic foot ulcers in patients with diabetic neuropathy.
- Trial name
- NCT03725917
- Testing
- Physiotherapy protocol
- Where
- Spain
- Volunteers
- 143 people
- Sponsor
- Universidad Complutense de Madrid
Spinal Duraplasty
Adherus™ Dural Sealant in Spinal Procedures
The purpose of this study is to test an experimental device, the Adherus AutoSpray and Adherus AutoSpray ET Dural Sealant, in spinal surgical procedures.
- Trial name
- NCT04498026
- Testing
- Adherus Dural Sealant System, DuraSeal Exact Dural Sealant System
- Where
- 14 sites in United States
- Volunteers
- 94 people
- Sponsor
- Stryker Craniomaxillofacial
Obesity Prevention, Wellness Program
Effect of Nutrition and Wellness Program on Health Parameter Among Employees
This study aims to evaluate the effectiveness of a worksite-based nutrition and wellness program in improving body composition, metabolic profile, and physical fitness among university employees who are overweight or obese.
- Conditions
- Obesity Prevention, Wellness Program, Body Composition, Nutrition
- Trial name
- WNWP (NCT07031726)
- Testing
- Worksite Nutrition and Wellness Program, Standard education
- Where
- Indonesia
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of Brawijaya
Intimate Partner Violence
IHEAL Trial: Effectiveness of a Health Promotion Intervention for Women Who Have Experienced Intimate Partner Violence
Living with an abusive partner has many negative impacts on women's health, safety and the quality of their lives. These issues often continue when women separate, or take steps to separate, from an abusive partner, and can make…
- Trial name
- NCT03573778
- Testing
- iHEAL, Information about Community Services
- Where
- 3 sites in Canada
- Volunteers
- 331 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Metastatic Breast Cancer
European Treatment Patterns and Outcomes Associated With First-Line CDK4/6 Inhibition and Hormonal Therapies
A retrospective observational analysis of de-identified data from a multinational medical record review to describe patient characteristics, treatment patterns, and effectiveness of palbociclib + AI as first-line therapy among…
- Trial name
- EUCHARIS (NCT05043506)
- Testing
- Palbociclib + aromatase inhibitor, Aromatase inhibitor
- Where
- 64 sites in Austria, Belgium and 5 more
- Volunteers
- 1,939 people
- Sponsor
- Pfizer
Coronary Artery Disease, Percutaneous Coronary Intervention
Efficacy and Safety of 1-year Duration of DAPT After GENOSS® DES Implantation in Patients with Coronary Artery Disease According to the Complex Higher-risk Procedure
The objective of study is to evaluate the efficacy and safety of 1 year duration of DAPT after GENOSS® DES Implantation in patients with coronary artery disease according to the complex higher-risk (and indicated) procedure.
- Conditions
- Coronary Artery Disease, Percutaneous Coronary Intervention, Dual Antiplatelet Therapy
- Trial name
- DAPTLong (NCT06075433)
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Genoss Co., Ltd.
Attachment Disorders
Effectiveness of a Parent Training Program for Parents of Children Adopted Internationally
This study will test the effectiveness of a parent training program aimed at helping children who are adopted internationally to develop secure, organized attachments to their parents.
- Trial name
- NCT00816621
- Testing
- ABC for Children Adopted Internationally, DEF for Children Adopted Internationally
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Cancer, Pleural Neoplasms
Safety, Efficacy, and Side Effects Study of Interventional Cryotherapy in the Pleural Space("ICE PLS")
The purpose of this study is to evaluate the safety, efficacy, and side effects of the CryoSpray Ablation(TM) System (CSA(TM) System) to treat neoplastic lesions on the parietal pleural surface.
- Trial name
- NCT00747916
- Testing
- CryoSpray Ablation (TM) System
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- CSA Medical, Inc.
Obesity and Obesity-related Medical Conditions
A Wearable Device and AI-Supported Diet and Exercise Intervention
This study implemented a personalized 6-month diet and exercise program to promote weight loss. Participants were recruited from outpatient clinics at the Department of Family Medicine, National Taiwan University Hospital.
- Trial name
- NCT06630663
- Testing
- A Wearable Device and AI-Supported Diet and Exercise intervention, standard care
- Where
- 2 sites in Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Exclusive Breastfeeding, Breastfeeding Self-Efficacy
Effect of a Self-Efficacy-Based Educational Intervention on Breastfeending in Primigravid Women: A Randomized Controlled Trial
This randomized controlled trial aims to evaluate the effect of a self-efficacy-based educational intervention on exclusive breastfeeding among primigravid women attending a primary care center in Mexico.
- Conditions
- Exclusive Breastfeeding, Breastfeeding Self-Efficacy, Pregnancy, Maternal Health Education
- Trial name
- PROMILACT (NCT07593716)
- Testing
- Breastfeeding Self-Efficacy Educational Program
- Where
- Mexico
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Pulmonary Disease, Chronic Obstructive
Tiotropium 18ug Inhalation Capsule Using a Handihaler® Among Korean COPD Patients
This is a descriptive observational open non-comparative study of the safety and efficacy of tiotropium inhalation capsule given at 18mcg once a day for 30 days among Korean patients with COPD.
- Trial name
- NCT00620516
- Where
- 71 sites in South Korea
- Volunteers
- 3,008 people
- Sponsor
- Boehringer Ingelheim
Neuromuscular Diseases
Effectiveness and Cost-effectiveness of the Energetic Program
Fatigue is present in at least 60% of the patients with a muscle disease and can be the most disabling symptom. In combination with other impairments, this often results in low levels of physical activity and decreased social…
- Trial name
- NCT02208687
- Testing
- Energetic, Control group
- Where
- Netherlands
- Volunteers
- 53 people
- Sponsor
- Radboud University Medical Center
Vaginal Flora Imbalance, ASC-US
"Lactobacillus Crispatus M247, LSIL and Microbiota"
Patients affected by ASC-US/ low-grade HPV cervical lesions will be randomly assigned to treatment arm vs control arm. The treatment arm will include the characterization of the vaginal microbiota at enrollment (T0), 4 months of…
- Conditions
- Vaginal Flora Imbalance, ASC-US, LSIL, HPV Infection
- Trial name
- NCT05808816
- Testing
- Lactobacillus Crispatus M247
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Coronary Heart Disease
Basel Stent Kosten Effektivitäts Trial Drug Eluting Balloons vs. Drug Eluting Stents in Small Vessel Interventions
The investigators hypothesize that in a real-world population undergoing percutaneous coronary intervention (PCI) for de-novo stenoses in small native vessels with a diameter <3 mm, drug eluting balloons (DEB) are non inferior to…
- Trial name
- BASKET-SMALL2 (NCT01574534)
- Testing
- Drug eluting balloon, Drug eluting stent
- Where
- 14 sites in Austria, Germany and 1 more
- Volunteers
- 758 people
- Sponsor
- University Hospital, Basel, Switzerland
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