Clinical trials: Intervention Effectiveness
Acute Myocardial Infarction
Effectiveness of Intracoronary Injection of Eptifibatide in Primary Coronary Intervention in STEMI Patients
The achievement of high local concentration of Eptifibatide, a GP 2b3a inhibitor,via direct intracoronary injection, promotes (in vitro) clot disaggregation.
- Trial name
- ICE (NCT00945308)
- Testing
- Eptifibatide
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Assaf-Harofeh Medical Center
Myocardial Infarction
Efficacy of the Adipose Graft Transposition Procedure (AGTP) in Patients With a Myocardial Scar: The AGTP II Trial
The purpose of this trial is to evaluate the efficacy of a pericardial adipose graft transposition (Adipose Graft Trasposition Procedure, AGTP) for the improvement of cardiac function in patients with a chronic myocardial…
- Trial name
- AGTP II (NCT02798276)
- Testing
- AGTP-treatment, Control
- Where
- 9 sites in Spain
- Volunteers
- 71 people
- Sponsor
- Antoni Bayés Genís
Proprioceptive Disorders
Exercises With Elastic Bands and Stability in Proprioception and Strength in Female Athletes of Taekwondo
Strength and proprioception exercises are used to improve the strength and unipodal balance of lower limbs in Taekwondo players.
- Trial name
- NCT04289584
- Testing
- Strength and proprioception exercises
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
End Stage Renal Failure on Dialysis, Renal Failure
Study on Fistuloplasty Using Flow Measurement Guidance
Hypothesis: The primary objective of this study is to assess whether using a flow measurement device, in this case the Transonics flow device, as an end-point to interventional treatment of diseased dialysis fistulae can help…
- Trial name
- NCT01643733
- Testing
- Using Flow measurements to guide fistula angioplasty (Transonics)
- Where
- 2 sites in Canada
- Volunteers
- 26 people
- Sponsor
- Richard Lindsay
Diabetes Mellitus, Type 2
Safety and Efficacy of Vildagliptin Plus Metformin (SPC) Treatment in Type 2 Diabetes Mellitus Patients
This study will assess the efficacy of vildagliptin plus metformin (SPC) treatment in type 2 diabetes mellitus patients uncontrolled by metformin monotherapy after 24 weeks treatment
- Trial name
- NCT01582243
- Testing
- Vildagliptin
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Novartis Pharmaceuticals
Stress
A Brief Acceptance Intervention for Stress to Improve Students' Well-Being
The goal of this randomized controlled trial is to test a brief psychological intervention that focusses on acceptance of stress in a student population.
- Trial name
- NCT06335615
- Testing
- Brief Acceptance Intervention, Psychoeducation
- Where
- Netherlands
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- VU University of Amsterdam
Alzheimer Disease
Gamma tACS in Alzheimer's Disease
Brain oscillations are ubiquitous in the human brain and have been implicated in cognitive and behavioral states defined in precisely tuned neural networks.
- Trial name
- GammAD (NCT04515433)
- Testing
- Gamma tACS (40 Hz) over the superior parietal cortex
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Gastroesophageal Reflux Disease
Study to Evaluate the Efficacy and Safety of FEXUCLUE Tablet
This observational study is a large-scale, prospective, and multi-institutional observational study. Patients from 19 to 75 years of age, will take a self-assessment (PRO) during the study period before and after administration…
- Trial name
- NCT05886933
- Testing
- Fexuprazan Hydrochloride
- Where
- South Korea
- Volunteers
- 9,846 people
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Gynecological Disease
The Effectiveness of a Virtual Reality-based Multisensory Intervention
This study explores the effectiveness of a virtual reality-based multisensory intervention for postoperative recovery in patients receiving gynecological surgery.
- Trial name
- NCT06922838
- Testing
- Virtual Reality intervention, Aromatherapy
- Volunteers
- 100 people
- Sponsor
- Weifang Medical University
Chronic Kidney Disease
A Study of Dapagliflozin in Chinese Adult Patients With Chronic Kidney Disease
The purpose of this study is to describe the efficacy and safety information with dapagliflozin in Chinese patients with chronic kidney disease.
- Trial name
- NCT06610526
- Testing
- Dapagliflozin
- Where
- 34 sites in China
- Volunteers
- 731 people
- Sponsor
- AstraZeneca
Recurrent Pilonidal Sinus Disease
Limberg and Karydakis Flap in Recurrent Pilonidal Sinus Disease
It was investigated whether there is a factor that can aid determination of the preferred technique by comparing the early Limberg flap and Karydakis procedure techniques for the treatment of recurrent pilonidal sinus.
- Trial name
- NCT02287935
- Testing
- Limberg flap, Karydakis procedure
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Adana Numune Training and Research Hospital
Ischemic Stroke, Acute Stroke
The Imperative Trial: Treatment of Acute Ischemic Stroke With the Zoom Reperfusion System
The trial is designed to assess the safety and efficacy of using the Zoom Reperfusion System in subjects diagnosed with acute ischemic stroke and undergoing a thrombectomy procedure within 8 hours of last known well.
- Trial name
- NCT04129125
- Testing
- Zoom Reperfusion System
- Where
- 28 sites in United States
- Volunteers
- 328 people
- Sponsor
- Imperative Care, Inc.
Children, Family Engagement
Effective Implementation Control Trial
This study will evaluate the effectiveness and implementation of a theory-driven, WhatsApp-based family engagement intervention designed to improve oral health among primary school children.
- Conditions
- Children, Family Engagement, Oral Health Behavior Change
- Trial name
- NCT07736443
- Testing
- SmileConnect
- Where
- Pakistan
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Muscle-invasive Bladder Cancer
Erdafitinib Monotherapy or in Combination With Cetrelimab in Muscle-invasive Bladder Cancer Patients With Fibroblast Growth Factor Receptor (FGFR ) Gene Alterations
Erdafitinib (ERDA) alone or in combination with cetrelimab (CET) as neoadjuvant treatment (prior to surgery) in subjects with muscle-invasive bladder cancer (MIBC) whose tumours express Fibroblast Growth Factor Receptor (FGFR…
- Trial name
- SOGUG-NEOWIN (NCT06511648)
- Testing
- Erdafitinib monotherapy, Cetrelimab and Erdafitinib combination
- Where
- 23 sites in France, Italy and 2 more
- Volunteers
- 90 people
- Sponsor
- Spanish Oncology Genito-Urinary Group
PreDiabetes
Examining the Impact of a Self-compassion Intervention on Physical Activity Behaviour Among People With Prediabetes
The investigators plan to examine whether teaching people at risk for type two diabetes to use self-compassion (orientation to care for oneself during difficult situations) helps them self-manage and increase their physical…
- Trial name
- NCT04863235
- Testing
- Control Group, Intervention Group
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Tobacco-Related Carcinoma
A Smoke-Free Home Intervention in Tribal Communities
This clinical trial evaluates a smoke-free home intervention for reducing exposure to secondhand smoke from commercial tobacco in homes of participants who live in rural tribal communities.
- Trial name
- NCT06583148
- Testing
- Best Practice, Smoking Cessation Intervention, Survey Administration
- Where
- United States
- Volunteers
- 575 people, healthy volunteers welcome
- Sponsor
- Emory University
Posttraumatic Stress Symptoms, Sexual Abuse
A Feasibility Mixed Methods Study of the Intervention Take Your Sexuality Back for Sexually Traumatized Women.
This study looks at the potential effects of a new group treatment called "Take Your Sexuality Back", designed for women who have experienced sexual trauma.
- Conditions
- Posttraumatic Stress Symptoms, Sexual Abuse, Sexual Trauma
- Trial name
- NCT07147855
- Testing
- Take your sexuality back
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Sykehuset Telemark
Mild Cognitive Impairment
Effectiveness of an ACT-Based Cognitive Intervention on Quality of Life and Cognitive Function in Elderly Residents With MCI
This study investigates the effects of an Acceptance and Commitment Therapy (ACT)-based cognitive intervention on Quality of Life (QOL) and cognitive function among elderly residents with Mild Cognitive Impairment (MCI) in…
- Trial name
- EACT (NCT06753578)
- Testing
- Acceptance and Commitment Therapy (ACT), standard care
- Where
- Spain
- Volunteers
- 215 people
- Sponsor
- Instituto de Investigación Marqués de Valdecilla
Hypertension, Coronary Arterial Disease
Comparative Effectiveness of Dual Antihypertensive Regimens in Patients After Percutaneous Coronary Intervention
This prospective randomized open-label study aims to compare the effectiveness of two dual antihypertensive therapy regimens in patients with arterial hypertension and coronary artery disease after elective percutaneous coronary…
- Conditions
- Hypertension, Coronary Arterial Disease, Percutaneous Coronary Intervention
- Trial name
- EDAM (NCT07683585)
- Testing
- Losartan + Hydrochlorothiazide, Amlodipine + Azilsartan
- Where
- Russia
- Volunteers
- 207 people
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Schizophrenia Cognition Autobiographical Memory Cognitive Remediation, SCHIZOPHRENIA 1 (Disorder)
Acceptability and Efficacy of Group Reminiscence Intervention in a Sample of Patients With Schizophrenia
The study aimed to test whether group reminiscence intervention for inpatients with schizophrenia is feasible, acceptable and preliminary effective.
- Conditions
- Schizophrenia Cognition Autobiographical Memory Cognitive Remediation, SCHIZOPHRENIA 1 (Disorder), Hospitalized Adult Patients
- Trial name
- NCT07512843
- Testing
- Group reminiscence therapy
- Where
- Jordan
- Volunteers
- 38 people
- Sponsor
- The Hashemite University
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