Clinical trials: Intervention Effectiveness
Alcohol Use, Posttraumatic Stress Disorder
CBT vs. Supportive Texts for PTSD & Hazardous Drinking (Project Better Study 2)
The study aims to test the efficacy of a CBT-enhanced text message intervention and a supportive text message intervention to reduce symptom burden in individuals with post-traumatic stress disorder symptoms and co-occurring…
- Trial name
- NCT06648395
- Testing
- CBT Text Messages, Supportive Messages
- Where
- United States
- Volunteers
- 345 people
- Sponsor
- University of Washington
Well-being
Evaluation of a Personalised Digital Intervention (EviBody) for Healthy and Sustained Lifestyle Behaviors and Well-being Among Adults: a Real-world Quasi-experimental Study
The goal of this quasi-experimental observational study is to evaluate the impact of a personally tailored digital intervention aimed to support a healthy lifestyle on well-being, lifestyle behaviors, and mental health among the…
- Trial name
- NCT05973383
- Testing
- EviBody- Basic, EviBody- Standard, EviBody- Premium
- Where
- Sweden
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Sophiahemmet University
Coronary Artery Disease
IRIS-Synergy Cohort in the IRIS-DES Registry
The purpose of this study is to evaluate the relative effectiveness and safety of Synergy stent compared to other drug eluting stents.
- Trial name
- IRIS Synergy (NCT02720419)
- Where
- 28 sites in South Korea
- Volunteers
- 3,000 people
- Sponsor
- Jung-min Ahn
Skeletal Class III Malocclusion
Efficacy of RME and Facemask Therapy for Class III Malocclusion
This multicenter randomized controlled trial compares the efficacy of Rapid Maxillary Expansion (RME) combined with facemask (FM) protraction versus FM protraction alone in treating growing children with skeletal Class III…
- Trial name
- NCT07053683
- Testing
- Combined RME and Facemask Therapy, Facemask Therapy Alone
- Where
- China
- Volunteers
- 358 people
- Sponsor
- Wuhan Integrated Traditional Chinese and Western Medicine Hospital
Autistic Disorders Spectrum
The Efficacy of Robot-enhanced Therapy for Children With Autism Spectrum Disorders
This trial will test the efficacy of robot-enhanced interventions for developing social skills in children with Autism Spectrum Disorders (ASD).
- Trial name
- DREAM-RCT (NCT03323931)
- Testing
- (2) robot--enhanced intervention, (1) discrete trial training / cognitive-behavior therapy
- Where
- Romania
- Volunteers
- 70 people
- Sponsor
- Babes-Bolyai University
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Mindfulness-Based Stress Reduction to Improve Well-being in Black Adult Cancer Survivors, Community Faith-based Mindfulness Ministry
This clinical trial evaluates the impact of a Mindfulness-Based Stress Reduction (MBSR) program adjusted to include Christian principles on well-being in Black adult cancer survivors.
- Trial name
- ComFaMM (NCT06767475)
- Testing
- Educational Intervention, Discussion, Mindfulness Relaxation
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cessation, Smoking
Efficacy of a Smoke-Free Homes Intervention
The purpose of this study is to test whether the integration of a smoke-free homes intervention into the clinical guidelines for tobacco cessation can encourage sustained smoking cessation in low-income primary care patients.
- Trial name
- SFH 5A RCT (NCT04547686)
- Testing
- Smoke-Free Homes Intervention, Quitline
- Where
- United States
- Volunteers
- 916 people
- Sponsor
- Emory University
Atrial Fibrillation
SPARK: Safety Study of Pradaxa in Atrial Fibrillation Patients by Regulatory Requirement of Korea
This is a prospective, non-interventional, open-label, multi-centre study. It will provide additional safety information of Pradaxa in Korean patients with non-valvular AF in clinical settings.
- Trial name
- NCT01774370
- Testing
- Pradaxa (Dabigatran etexilate mesilate)
- Where
- South Korea
- Volunteers
- 3,182 people
- Sponsor
- Boehringer Ingelheim
Adolescent Behavior, Substance Use
Evaluating the Effectiveness of a Drug Education and Diversion Program for Middle and High School Students
The primary goal of this study is to evaluate the effectiveness of the iDECIDE curriculum as an alternative to punitive responses for school-based substance use infractions.
- Conditions
- Adolescent Behavior, Substance Use, Youth, Health Risk Behaviors
- Trial name
- iDECIDE (NCT05321563)
- Testing
- iDECIDE (Drug Education Curriculum: Intervention, Diversion, and Empowerment)
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Massachusetts General Hospital
Contraception, Menorrhagia
A Study to Evaluate the Effectiveness of Essure Post-NovaSure Radiofrequency Endometrial Ablation Procedure Following a Successful Essure Confirmation Test
The purpose of the post approval study is to evaluate the effectiveness and safety of the Essure System when a NovaSure Endometrial Ablation procedure is performed following a successful Essure Confirmation Test.
- Trial name
- ESS-NSPAS (NCT01740687)
- Testing
- ESS305 (Essure, BAY1454032), NovaSure
- Where
- 17 sites in United States
- Volunteers
- 211 people
- Sponsor
- Bayer
Prostatectomy, Pelvic Floor Disorders
The Efficacy of Pre-operative Educational Pelvic Floor Intervention on Urinary Continence
Prostate cancer is the most common type of cancer between male population and urinary incontinence (UI) is the most common of long-term sequelae.
- Trial name
- NCT03714984
- Testing
- Pre operative exercise, Control Group
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- European Institute of Oncology
Ocular Pain
Evaluate the TetraLens, a Tetracaine Releasing Therapeutic Bandage Contact Lens in Patients Undergoing PRK Procedure
The goal of this clinical trial is to determine the safety, efficacy, and comfort of the investigational TetraLens bandage contact lens in patients who have undergone photorefractive keratectomy (PRK).
- Trial name
- NCT06085352
- Testing
- TetraLens bandage contact lens, Control Acuvue Oasys Bandage contact Lens
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Vance Thompson Vision
Pancreatitis
Idiopathic Recurrent Acute Pancreatitis (IRAP)
The purpose of this study is to collect standardized data on the diagnosis and management of idiopathic (unknown cause) recurrent acute pancreatitis.
- Trial name
- IRAP (NCT01133535)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Wake Forest University Health Sciences
HFpEF - Heart Failure With Preserved Ejection Fraction
Testing the CHAT Program for Patients With Heart Failure
The researchers are studying whether an intervention that involves video-based educational content and a health coach is acceptable, feasible, and effective for people with Heart Failure with Preserved Ejection Fraction (HFpEF).
- Trial name
- NCT06994325
- Testing
- Conversations Helpful for Awareness of Illness Trajectory (CHAT) Intervention, Standard of Care (SOC)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Weill Medical College of Cornell University
Hypoxia, Brain, Hypoxia-Ischemia, Brain
Home Stimulation for Brain-Asphyxiated Infants
This study examines the potential benefits of a home stimulation program to treat infants who have suffered from brain asphyxiation (lack of oxygen). The program involves one year of stimulatory activities.
- Trial name
- NCT00006516
- Testing
- Infant stimulation
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Acne Scars - Mixed Atrophic and Hypertrophic, Ice Pick Scars
Evaluation of Efficacy and Safety of HCC_45 for the Correction of Acne Scars of the Face
Acne scars represent a frequent complication of moderate/severe acne and may negatively impact on psychosocial and physical well-being of acne patients.
- Conditions
- Acne Scars - Mixed Atrophic and Hypertrophic, Ice Pick Scars, Rolling Scars, Boxcar Scars
- Trial name
- NCT05691049
- Testing
- HCC_45
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- IBSA Farmaceutici Italia Srl
Smoking Cessation
Benefits of a Cognitive Behavioral Therapy Intervention for Smoking Cessation Supported by Virtual Reality Smoking Cue Exposure
Cognitive-behavioral therapy (CBT) combined with medication is an established intervention for smoking cessation. However, long-term abstinence rates of maximum 35% are yielded.
- Trial name
- ViReTa (NCT03707106)
- Testing
- CBT smoking cessation, virtual reality based cue exposure, progressive muscle relaxation
- Where
- 2 sites in Germany
- Volunteers
- 246 people
- Sponsor
- University Hospital Tuebingen
Binge Eating, Binge-Eating Disorder
Identifying Effective Technological-based Augmentations to Enhance Outcomes From Self-help Cognitive Behavior Therapy for Binge Eating
The purpose of this study is to test the feasibility, acceptability and efficacy of two technology-based intervention systems (including an Advanced Digital Data Sharing (ADDS) with Coaches or a smartphone-based just-in-time…
- Conditions
- Binge Eating, Binge-Eating Disorder, Bulimia Nervosa, Bulimia
- Trial name
- CONQUER (NCT05937243)
- Testing
- Base self-help CBT program, Just-in-time, adaptive intervention (JITAIs) system, Advanced Digital Data Sharing (ADDS) with Coaches
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Drexel University
Alcohol Consumption
Comparing the Efficacy of Several Popular Online Interventions to Reduce Hazardous Alcohol Consumption
There are a number of popular, freely available online interventions targeting hazardous alcohol consumption. Unfortunately, most have limited or no published evidence regarding their efficacy.
- Trial name
- NCT03060135
- Testing
- Check Your Drinking, Hello Sunday Morning
- Where
- Canada
- Volunteers
- 878 people
- Sponsor
- Centre for Addiction and Mental Health
Pulmonary Disease, Chronic Obstructive
Tiotropium 18ug Inhalation Capsule Using a Handihaler® Among Korean COPD Patients
This is a descriptive observational open non-comparative study of the safety and efficacy of tiotropium inhalation capsule given at 18mcg once a day for 30 days among Korean patients with COPD.
- Trial name
- NCT00620516
- Where
- 71 sites in South Korea
- Volunteers
- 3,008 people
- Sponsor
- Boehringer Ingelheim
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