Clinical trials: Intervention Effectiveness
Suspected CSF Shunt Obstruction
ShuntCheck-Micro-Pumper Pediatric Clinical Outcomes Study
Primary objective is to demonstrate that data collected from ShuntCheck-Micro-Pumper (SCMP) testing results can be used in conjunction with imaging to diagnose shunt patency or obstruction in pediatric/adolescent subjects…
- Trial name
- NCT01881711
- Testing
- ShuntCheck-Micro-Pumper (SCMP), Imaging
- Where
- 11 sites in United States
- Volunteers
- 400 people
- Sponsor
- NeuroDx Development
Well-being
The Effectiveness of Engagement-based Personalization of a Digital Mental Health Intervention
This study will investigate the effectiveness of an engagement-based personalized 2-week mobile wellbeing intervention, vs the effectiveness of a non-personalized 2-week mobile wellbeing intervention.
- Trial name
- NCT05300906
- Testing
- personalized 2-week mobile wellbeing intervention, non-personalized 2-week mobile wellbeing intervention
- Where
- Netherlands
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Twente
Attention Deficit Hyperactivity Disorder
Effectiveness of a Tailored Occupational Therapy Intervention for Women With ADHD
Although woman are diagnosed with Attention-deficit hyperactivity disorder (ADHD) at a 1:3 ratio with men, recent research suggests that woman may experience the same levels of adult ADHD as men but are underdiagnosed because…
- Trial name
- NCT03203928
- Testing
- Occupational Therapy Intervention for Women with ADHD
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Columbia University
Cardiometabolic Conditions, Hypertension (HTN)
To Test the Effectiveness and Implementation Approach of a 3-month PILI Pasifika Program Lifestyle Program With Components of Social Determinants of Health Activities in Real-world Settings (Clinical and Non-clinical Settings) Across 3 Years
In this study, the investigators are conducting a Type 3 hybrid effectiveness-implementation trial to evaluate the implementation of the Community Health Workers (CHW)-delivered PILI Pasifika Program (PPP) across 3 regions, the…
- Conditions
- Cardiometabolic Conditions, Hypertension (HTN), Dyslipidemia, Pre-diabetes
- Trial name
- NCT07387393
- Testing
- PILI (Partnership for Improving Lifestyle Intervention) Pasifika Program
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- University of Hawaii
Major Depressive Disorder
Efficacy of Pythagorean Self-Awareness Intervention for Major Depressive Disorder
The present study explored the effects of the implementation of the Pythagorean Self Awarenes Intervention (PSAI) on patients diagnosed with major depressive disorder.
- Trial name
- NCT04536714
- Testing
- Pythagorean Self-Awareness Intervention program
- Where
- Greece
- Volunteers
- 69 people
- Sponsor
- Evgenia E. Psarraki
Prevention
Optimizing PrEP Uptake and Adherence Among Male Sex Workers
"PrEPare for Work" is a randomized controlled trial (RCT) whose goal is to test the efficacy of a behavioral intervention (Short Title: PrEPare for Work) in improving PrEP uptake, adherence, and persistence among male sex workers…
- Trial name
- P4W (NCT05736614)
- Testing
- Stage 1 Strength Based Case Management (SBCM) Condition, Stage 2 PrEPare for Work Intervention Condition
- Where
- 5 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Brown University
Dental Anxiety
Efficacy of Oral Midazolam for Sedation and Amnesia in Preschool Children Undergoing Dental Procedures
Dental anxiety frequently impedes effective dental care in pediatric patients. This study aimed to compare the efficacy and safety of two doses (0.3 mg/kg and 0.6 mg/kg) of oral midazolam for sedation and amnesia in preschool…
- Trial name
- NCT06887712
- Testing
- Oral midazolam
- Where
- Vietnam
- Volunteers
- 80 people
- Sponsor
- Hanoi Medical University
Moderate Plaque Psoriasis, Moderate Psoriasis
Study to Evaluate the Effectiveness of Risankizumab in Participants With a Recent Diagnosis of Moderate Plaque Psoriasis in a Real-life Setting in Greece
Psoriasis is a skin disorder wherein skin cells multiply faster than normal, making the skin itchy and look patchy and red. It is caused by an overactive immune system where the body attacks healthy tissue by mistake.
- Conditions
- Moderate Plaque Psoriasis, Moderate Psoriasis, Psoriasis
- Trial name
- REDEFINE (NCT06247319)
- Where
- 22 sites in Greece
- Volunteers
- 250 people
- Sponsor
- AbbVie
Carpal Tunnel Syndrome, Pain, Chronic
Combined Physical and Psychological Intervention in Carpal Tunnel Syndrome Patients With Nociplastic Pain
This randomized, assessor-blinded, parallel-group trial evaluated the effectiveness of adding a psychologically informed pain-management intervention to standardized physical rehabilitation in adults with electrodiagnostically…
- Trial name
- NCT05915611
- Testing
- Standardized Carpal Tunnel Syndrome Rehabilitation, Psychologically Informed Pain-Management Program, Attention-Matched Health Education
- Where
- Egypt
- Volunteers
- 178 people
- Sponsor
- Ahram Canadian University
Chronic Alcoholism
Safe and Effective Sedation in Chronic Alcoholic Patients Underwent Diagnostic Endoscopic Procedures: Study Comparing Midazolam and Propofol With Midazolam
Sedative endoscopic examination using sedative premedication has been undertaken to induce conscious sedation for comfortable and painless endoscopy.
- Trial name
- NCT01617707
- Testing
- Midazolam plus propofol, Midazolam
- Where
- South Korea
- Volunteers
- 11 people
- Sponsor
- Yonsei University
Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase
Clinical Study of Asciminib in Previously Treated Indian Patients With Ph+ CML-CP Without T315I Mutation and in Patients With Ph+ CML-CP With T315I Mutation
The Drugs Controller General of India (DCGI) has granted approval for Asciminib film-coated 40 mg tablets on 20 Oct 2023 with the condition to perform a Phase IV clinical study in Indian patients with Philadelphia…
- Trial name
- ASC4INDIA (NCT06427811)
- Testing
- Asciminib
- Where
- 10 sites in India
- Volunteers
- 85 people
- Sponsor
- Novartis Pharmaceuticals
Pediatric Obesity
Study on the Tailored Intervention Strategy of Childhood Obesity Based on Monitoring Physical Activities and Dietary Behaviors
The project aims at developing the tailored intervention strategy of childhood obesity based on monitoring physical activities with accelerometer and dietary behaviors using diary.
- Trial name
- NCT02228434
- Testing
- Monitoring and Tailored prescription, Happy 10 program, Specified nutrition education
- Where
- China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Wang Jingjing
Guideline Implementation
Retrospective Evaluation of ASIPP Guidelines Implementation
To demonstrate clinically significant improvements in the patients treated following ASIPP guidelines compared to the patients who were treated prior to the establishment of ASIPP guidelines.
- Trial name
- NCT00372164
- Testing
- American Society of Interventional Pain Physician Guidelines
- Where
- United States
- Sponsor
- Pain Management Center of Paducah
COVID-19
A Study to Learn About a Repeat 5-Day Treatment With the Study Medicines (Called Nirmatrelvir/Ritonavir) in People 12 Years Old or Older With Return of COVID-19 Symptoms and SARS-CoV-2 Positivity After Finishing Treatment With Nirmatrelvir/Ritonavir
The purpose of this study is to learn about the safety and effects of nirmatrelvir/ritonavir for the potential treatment of COVID-19 rebound.
- Trial name
- NCT05567952
- Testing
- nirmatrelvir, ritonavir
- Where
- 84 sites in United States, Canada and 3 more
- Volunteers
- 436 people
- Sponsor
- Pfizer
Risk for an Alcohol-Exposed Pregnancy, Risk for Marijuana-Exposed Pregnancy
CHOICES-TEEN Randomized Controlled Trial
This randomized controlled trial will: 1) Test the efficacy of the CHOICES-TEEN (CT) intervention compared with an Attentional Control (AC) condition on reducing the risk of substance-exposed pregnancy (SEP) and HIV/STI among…
- Conditions
- Risk for an Alcohol-Exposed Pregnancy, Risk for Marijuana-Exposed Pregnancy, Risk for Substance-Exposed Pregnancy, HIV Risk
- Trial name
- NCT05368571
- Testing
- CHOICES-TEEN, Health and Life Skills Education
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Danielle Parrish
End Stage Renal Disease
Fluid Overload in Peritoneal Dialysis
The objective of this study is to determine the effectiveness of treating peritoneal dialysis (PD) patients with fluid overload by a structured nurse-lead intervention protocol.
- Trial name
- NCT02557347
- Testing
- Aggressive fluid management
- Where
- Hong Kong
- Volunteers
- 102 people
- Sponsor
- Chinese University of Hong Kong
Depressive Disorder, Major, Persistent Depressive Disorder
Effectiveness of an Ecological Momentary Emotion Regulation Intervention
This two-armed randomized controlled trial aims to investigate the effectiveness of an emotion regulation intervention in individuals with and without depressive disorders.
- Conditions
- Depressive Disorder, Major, Persistent Depressive Disorder, Healthy
- Trial name
- NCT06311136
- Testing
- Valence-Specific Ecological Momentary Intervention
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Stroke, TIA
Querying Stroke Unit Nursing Interventions in the Emergency Department
The aim of the study is to monitor if specialized stroke nurses as team partners in the ED can reduce hospital acquired infections.
- Trial name
- NCT04011514
- Testing
- Dedicated stroke nurse care in ED
- Where
- Denmark
- Volunteers
- 800 people
- Sponsor
- Herlev Hospital
Fear of Childbirth
Effects of Mandala Coloring and Music Listening on Fear of Childbirth
This randomized controlled trial evaluates the effects of mandala coloring and music listening on fear of childbirth among pregnant women.
- Trial name
- MAMFOC (NCT07775963)
- Testing
- Mandala Coloring, Music Listening
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Osmaniye Korkut Ata University
Fibromyalgia, Chronic Fatigue Syndrome
Effectiveness and Health Benefits of a Nutritional, Chronobiological and Physical Exercise Intervention in Fibromyalgia and Chronic Fatigue Syndrome (SYNCHRONIZE +)
Chronic pain, fatigue and insomnia are classical symptoms of Fibromyalgia and Chronic Fatigue Syndrome, affecting seriously life quality. Non-pharmacological multicomponent approach is gaining relevance in Fibromyalgia treatment.
- Trial name
- SYNCHRONIZE + (NCT05719493)
- Testing
- multicomponent treatment
- Where
- Spain
- Volunteers
- 86 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
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