Clinical trials: Intervention Effectiveness
Sedentary Lifestyle
The Engaged4Life Study: Enhancing the Health-Promoting Effects of Older Adults' Activity Portfolios
This study designs and tests a multi-component intervention- Engaged4Life- designed to enhance physical activity (PA), cognitive activity (CA), social interaction (SI) and personal meaning (PM) in low-engaged community-dwelling…
- Trial name
- NCT03337204
- Testing
- Technology-assisted self-monitoring, Workshop and Peer Mentoring
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Boston College
Psoriasis
Efficacy Study of Dietary Intervention and Weight Loss in Improving Psoriasis
This is a multicenter randomized controlled clinical trial evaluating the impact of a structured non pharmacological intervention consisting in intensive weight reduction (qualitative and quantitative changes in diet associated…
- Trial name
- NCT01714284
- Testing
- Informative, Diet and Exercise
- Where
- 11 sites in Italy
- Volunteers
- 303 people
- Sponsor
- Centro Studi Gised
Hamstring Injury
Miodural Bridge Stretching in Posture Modification in Professional Footballers
Fatigue influences the kinematics of the knee. Decreasing the tone of the suboccipital musculature may decrease the tone of the knee flexors.
- Trial name
- NCT04290065
- Testing
- Manual therapy
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Frailty, Aortic Stenosis
RESTORE-TAVI Pilot
This is a pilot randomised control study assessing the feasibility and effectiveness of a perioperative multi-component intervention aimed at reducing adverse hospital events and improving functional outcomes in patients with…
- Trial name
- NCT06121921
- Testing
- Perioperative multi-component intervention
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Barts & The London NHS Trust
Tooth Bleaching
The Efficacy and Safety of Tooth Bleaching Procedure Using Y10 Whitening Toothpaste and RF Current
Study title: The Efficacy and Safety of tooth bleaching procedure using Y10 Whitening toothpaste and RF current The Device: The Brighttonix Y10 Tooth Whitening system is indicated for use in painless non-invasive tooth whitening…
- Trial name
- NCT02841514
- Testing
- The Y10 Tooth Whitening system including the Y10 toothpaste and the Y10 device, OTC toothpaste and an unoperated Y10 device
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brighttonix Medical Ltd.
PTSD
TIMBER Psychotherapy and Ketamine Single Infusion in Chronic PTSD
Background: The poor prognosis and public health burden of PTSD necessitates the development of more effective and broader treatment approaches.
- Trial name
- NCT02766192
- Testing
- Ketamine, TIMBER Psychotherapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Cooper Health System
Thrombocytopenia; Drugs, Chronic Liver Disease
Efficacy of Avatrombopag in Thrombocytopenic Patients With Chronic Liver Disease Undergoing an Elective Procedure
In this study, investigators aimed to evaluate the efficacy of Avatrombopag in thrombocytopenic patients with chronic liver disease undergoing an elective invasive procedure through a prospective, non-randomized controlled…
- Trial name
- NCT04915287
- Testing
- Avatrombopag maleate, Platelet transfusion, Medicine
- Where
- China
- Volunteers
- 476 people
- Sponsor
- Chinese PLA General Hospital
Self Efficacy, Loneliness
New in Town-Internet Intervention for Migrants
New in Town is an internet intervention for migrants that aims at increasing social self-efficacy. The study aim is to evaluate its effectiveness.
- Conditions
- Self Efficacy, Loneliness, Social Skills
- Trial name
- NCT04088487
- Testing
- New in Town-Interner Intervention for Migrants
- Where
- Poland
- Volunteers
- 178 people
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Obesity, Healthy Diet
Pricing Interventions Based on Energy Content in Restaurants
The goal of this clinical trial is to examine the impact of price decreases based on energy content in a full-service restaurant on immediate dietary consumption (in terms of kilocalories (kcals), sugar, fat, and salt intake) and…
- Conditions
- Obesity, Healthy Diet, Eating Behavior
- Trial name
- NCT05818345
- Testing
- Pricing intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Peripheral Arterial Disease, Claudication, Intermittent
Safety and Efficacy of Atherectomy on VasculaR Functions
Interventional strategies aim to restore tissue perfusion. However, despite the simple reopening of a narrowed artery they affect endothelial function, perpetuating dysfunctional vascular homeostasis.
- Trial name
- SAVioR (NCT04092972)
- Testing
- Atherectomy, POBA and DCB
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital, Essen
Posttraumatic Stress Disorder
Testing the Efficacy of a Mindfulness- and Acceptance-Based Smartphone App for PTSD: A Randomized Controlled Trial
The purpose of the study is to test the feasibility and acceptability of a mindfulness- and acceptance-based smartphone app (MABSA) intervention for college student veterans with posttraumatic stress disorder (PTSD) symptoms.
- Trial name
- NCT04861311
- Testing
- Mindfulness/Acceptance-Based Smartphone App (MABSA) Intervention
- Volunteers
- 64 people
- Sponsor
- University of Nevada, Las Vegas
Clostridium Difficile
To Determine the Feasibility of a Fidaxomicin Study in Neonates and to Assess C. Difficile (Clostridium Difficile) Involvement in the Pathogenesis
The objective of this multi-center, prospective observational study is to determine the feasibility of a potential interventional study with fidaxomicin.
- Trial name
- DAISY (NCT01533844)
- Where
- 9 sites in France, Germany and 2 more
- Volunteers
- 1 people
- Sponsor
- Astellas Pharma Europe B.V.
Alcohol Prevention, Mental Health
Feasibility and Effectiveness of Gamified Digital Intervention to Prevent Alcohol and Mental Health Risks
This study evaluates the impact of a novel smartphone application on alcohol consumption, alcohol-related problems, and psychological well-being.
- Trial name
- NCT07546604
- Testing
- Gamified Social App Supporting Womens' Health & Well-being, Psychoeducational Resource Library Access Only
- Where
- United States
- Volunteers
- 1,752 people, healthy volunteers welcome
- Sponsor
- Loyola Marymount University
Insomnia
Sleep-MOMagement: Improving Postpartum Sleep in First-time Mothers Through Tailored Behavioral Approaches.
The goal of this clinical trial is to find out if person-centered behavioral interventions can help first-time mothers sleep better after childbirth.
- Trial name
- SleepMOM (NCT07345065)
- Testing
- Behavioural Sleep Managament, Behavioural Aerobic Exercise Therapy
- Where
- 2 sites in Belgium
- Volunteers
- 135 people
- Sponsor
- De deyne Manon
Clinical High Risk for Psychosis (CHR), Suicidal Ideation
Developing a Recovery-Oriented Suicide Prevention Program for Young People at Clinical High Risk for Psychosis
Young people at clinical high risk for psychosis are more likely to experience suicide thoughts than the general population, but there are few suicide prevention programs designed specifically for them.
- Conditions
- Clinical High Risk for Psychosis (CHR), Suicidal Ideation, Psychosis, Suicidal Behavior
- Trial name
- NCT07756567
- Testing
- Suicide Prevention Intervention, Standard Care (in control arm)
- Where
- 2 sites in United States
- Volunteers
- 108 people
- Sponsor
- University of California, San Diego
Locally Advanced Cancer, Metastatic Cancer
Evaluating Interventional Radiology for Cancer Pain Management
Each year, the number of new cancer cases increases globally and the associated pain remains a major concern. The scientific literature shows that the prevalence and severity of cancer-related pain have decreased thanks to new…
- Trial name
- RI-LieF (NCT07529314)
- Testing
- Self-reported questionnaires
- Volunteers
- 125 people
- Sponsor
- Hospices Civils de Lyon
Patient Satisfaction and Efficacy of Bowel-preparation, Colon Cancer Prevention
Effectiveness of Nurse Tele-consultation on the Quality of Elective Colonoscopy, Procedure-related Anxiety, and Financial Toxicity
This is a multicenter, non-pharmacological, experimental, prospective, randomized study, with two arms (1:1) in a single-blind design.
- Trial name
- NCT06887244
- Testing
- Tele-consultation
- Where
- Italy
- Volunteers
- 534 people
- Sponsor
- National Cancer Institute, Naples
Diabetes, Diabetes Mellitus, Type 1
An Observational Study to Assess Safety and Effectiveness of Intravenous NovoRapid® in Hospitalised Subjects
This study is conducted in Asia. The aim of this observational study is to evaluate the side effects profile and benefits of using intravenous insulin aspart infusion in hospitalised subjects under normal clinical practice…
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- NCT00700648
- Testing
- insulin aspart
- Where
- India
- Volunteers
- 3,024 people
- Sponsor
- Novo Nordisk A/S
Migraine Headache
Effectiveness of Education and Relaxation Program on Migraine Related Disability in Patients Attending Headache Clinic
Migraine causes severe impairment in quality of life (QOL) both during and between attacks. Migraine also increases absenteeism, reduces productivity at work as well as at home, disrupts social and family relationships, also is…
- Trial name
- NCT05039996
- Testing
- education and relaxation program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Painless Gastrointestinal Endoscopy
A Clinical Study to Evaluate the Efficacy and Safety of Hyoscine Butylbromide Capsules for Preoperative Preparation in Painless Gastrointestinal Endoscopy Procedures
Gastrointestinal endoscopy procedures, including upper gastrointestinal endoscopy and colorectal endoscopy, represent a fundamental and important method for examining and managing digestive tract diseases, with both diagnostic…
- Trial name
- NCT07271303
- Testing
- Hyoscine Butylbromide
- Volunteers
- 74 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
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