Clinical trials: Intervention Phase
Diagnostic Techniques and Procedures, Clinical Laboratory Techniques
Clinical Validation of an Artificial Intelligence System for the Interpretation of Laboratory Test Results Combined With a Structured Medical History
This study evaluates a certified artificial intelligence (AI) based software system that automatically interprets laboratory test results in combination with a structured, dynamically generated medical history questionnaire.
- Conditions
- Diagnostic Techniques and Procedures, Clinical Laboratory Techniques, Triage
- Trial name
- LTC-VALID (NCT07810491)
- Testing
- AI-based laboratory result interpretation software
- Where
- 2 sites in Poland
- Volunteers
- 899 people
- Sponsor
- Labplus Sp. z o.o.
End-stage Renal Disease
Network Interventions to Reduce Disparities in Living Kidney Donation
For this current phase of the larger project, the investigators will survey transplant candidates as well as the participants family and friends to understand the barriers to volunteering and evaluation.
- Trial name
- NCT05255757
- Testing
- Script Intervention, Search Intervention
- Where
- 2 sites in United States
- Volunteers
- 164 people
- Sponsor
- Penn State University
Urinary Tract Infections, Bladder Cancer
Antimicrobial Prophylaxis in Patients Who Underwent a Transurethral Resection of Bladder (TURB)
Antimicrobial prophylaxis in urological procedures is aimed to reduce the risk of local and systemic postoperative infections such as urinary tract infection or surgical site infection.
- Conditions
- Urinary Tract Infections, Bladder Cancer, Urologic Surgical Procedures
- Trial name
- NCT04209192
- Testing
- Fosfomycin Tromethamine 3G Sachet, Amikacin
- Where
- Mexico
- Volunteers
- 75 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Sedation, Anxiety
A Study to Evaluate the Clinical Efficacy, Safety and Tolerability of ARX-F03 Sublingual Sufentanil/Triazolam NanoTab™ in Patients Undergoing an Elective Abdominal Liposuction Procedure
The purpose of this study is to evaluate the safety and effectiveness of a study medication that contains a combination of a pain medication, sufentanil, and a sedative, triazolam.
- Conditions
- Sedation, Anxiety, Pain
- Trial name
- NCT00894699
- Testing
- Sublingual Sufentanil/Triazolam NanoTab™ (ARX-F03)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Talphera, Inc
Autism Spectrum Disorder
Virtual Reality Intervention for Skill Acquisition Support in Autism Spectrum Disorder (ASD)
A Randomized Controlled Phase II study to assess the efficacy of Floreo VR (Virtual reality) Building Social Connections as treatment for social skills in children with Autism Spectrum Disorder (ASD)
- Trial name
- NCT05791071
- Testing
- Floreo VR Building Social Connections
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Floreo, Inc.
CNS Lymphoma
A Phase I/II Study to Investigate the Use of VORAXAZE™ As Intended Intervention in Patients with CNSL
This phase I-II trial is intented to demonstrate tolerability (i.e. absence of severe non-hematological toxicity) and efficacy of intended intervention with repeated doses of Voraxaze, in addition to leucovorin (LV), in patients…
- Trial name
- VALIDATE (NCT04841434)
- Testing
- Voraxaze Injectable Product
- Where
- Germany
- Volunteers
- 18 people
- Sponsor
- Charite University, Berlin, Germany
Chronic Myelogenous Leukemia in Chronic Phase
RWE,NIS,Prospective Study for the Effectiveness, Tolerability and Adherence of Asciminib in Saudi Arabia. (ASC4REAL)
This is a non-interventional, prospective, observational single arm study describing the real-world effectiveness, tolerability, adherence, Healthcare Resource Utilization (HCRU) and Patient-Reported Outcome (PRO) data of…
- Trial name
- ASC4REAL (NCT06684964)
- Testing
- asciminib
- Where
- 4 sites in Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Kidney Failure
Icodextrin Study to Test Short-Term Safety, Tolerability and Preliminary Efficacy of Sodium-Free Solution in PD Patients
Patients with kidney failure rely on dialysis for sodium and fluid removal. The importance of a sodium and fluid balance in patients with kidney disease is very important.
- Trial name
- NCT05185999
- Testing
- Icodextrin/Dextrose
- Where
- 2 sites in Canada
- Volunteers
- 10 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Atrial Flutter
Cardiac Electrophysiological Study
The purpose of the study is to measure the effects of AZD1305 on cardiac electrophysiological properties and intracardiac pressures
- Trial name
- NCT00616629
- Testing
- AZD1305
- Where
- 13 sites in Denmark, Finland and 2 more
- Volunteers
- 55 people
- Sponsor
- AstraZeneca
Intimate Partner Violence (IPV), Earning Outcomes
Zithandani Stepping Stones and Creating Futures - Phase 2 Pilot
The goal of this uncontrolled intervention study is to assess whether Zithandani Stepping Stones and Creating Futures is feasible to deliver, acceptable for participants, safe for participants and to estimate effect sizes, in…
- Conditions
- Intimate Partner Violence (IPV), Earning Outcomes, Mental Health, Couple Communication
- Trial name
- NCT06975137
- Testing
- Zithandani Stepping Stones and Creating Futures
- Where
- South Africa
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Type 2 Diabetes Mellitus, Cardiovascular Autonomic Dysfunction
Nurse-Led Self-Management and Breathing Intervention in Type 2 Diabetes
Brief Summary This study evaluated the effect of a structured nurse-led home-based self-management and paced-breathing intervention on cardiovascular autonomic function and blood pressure among adults with type 2 diabetes…
- Trial name
- NCT07847177
- Testing
- Structured Nurse-Led Home-Based Self-Management and Paced-Breathing Program
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Aziza Ibrahim Mohamed
Dyspnea
Trial of a Breathlessness Intervention Service for Intractable Breathlessness
The aim of this study is to evaluate the impact of a Breathlessness Intervention Service (BIS) on the quality of life of patients and families affected by intractable breathlessness.
- Trial name
- NCT00678405
- Testing
- Breathlessness Intervention Service, Best supportive care (Standard Care)
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
CLL (Chronic Lymphocytic Leukemia)
CLL-IMPACT: A Clinical Nutrition Trial Investigating Immune and Metabolic Changes in Early-Stage CLL
The goal of this clinical trial is to investigate whether a short-term (4-week) whole-food, plant-based (WFPB) diet has an effect on metabolism, immune function, and disease activity in early-stage chronic lymphocytic leukemia…
- Trial name
- CLL-IMPACT (NCT07487428)
- Testing
- Diet
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Technical University of Munich
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
A Feasibility Trial of a Web Based App Intervention in Hormone Positive Breast Cancer Patients to Improve Adherence to Endocrine Therapy
This clinical trial looks at the use of an internet-based application (app) intervention in improving adherence to endocrine therapy (ET) among patients with early stage hormone receptor-positive HER2-negative breast cancer.
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, HER2-Negative Breast Carcinoma, Hormone Receptor-Positive Breast Carcinoma
- Trial name
- NCT05488145
- Testing
- Best Practice, Internet-Based Intervention, Questionnaire Administration
- Where
- 4 sites in United States
- Volunteers
- 21 people
- Sponsor
- Emory University
Malignant Melanoma
ECT-Pembrolizumab in Patients With Unresectable Melanoma With Superficial or Superficial and Visceral Metastases
This is a Phase 2 multicenter, open label, non-randomized, interventional study enrolling 53 patients.The objectives and purposes of the clinical study described herein are to determine if concomitant Pembrolizumab (Keytruda) and…
- Trial name
- NCT03448666
- Testing
- Pembrolizumab
- Where
- Italy
- Sponsor
- European Institute of Oncology
Chronic Myeloid Leukemia
Non-interventional Treatment Patterns Study in Chronic Phase Chronic Myelogenous Leukemia (CP-CML)
The purpose of this study is to evaluate treatment patterns and associated outcomes for CP-CML patients who fail Imatinib 400 mg daily in a real-world setting.
- Trial name
- NCT01394666
- Volunteers
- 150 people
- Sponsor
- Bristol-Myers Squibb
Non Hodgkin Lymphoma, Heart; Functional Disturbance
Improving Exercise Capacity With a Tailored Physical Activity Intervention
The purpose of this research is to test whether participating in either a physical activity intervention or a series of educational classes will help to preserve exercise capability, heart function, brain-based activities (like…
- Conditions
- Non Hodgkin Lymphoma, Heart; Functional Disturbance, Hodgkin Lymphoma, Quality of Life
- Trial name
- PALS (NCT05595577)
- Testing
- Exercise with Trainerize application, Cardiopulmonary exercise testing, MRI scan
- Where
- 2 sites in United States
- Volunteers
- 105 people
- Sponsor
- Wake Forest University Health Sciences
Chronic Kidney Disease (Stages 4 and 5)
Feasibility of the COMFORT (COmplex Symptom Management Intervention FOR adulTs With Advanced Kidney Disease) Intervention for Adults With Advanced Kidney Disease and Their Informal Caregivers
The purpose of this randomized feasibility study is to examine whether the COMFORT intervention is feasible and acceptable for adults with advanced kidney disease and their informal caregivers.
- Trial name
- COMFORT (NCT07815639)
- Testing
- COMFORT Intervention, Usual Care
- Where
- 2 sites in Denmark
- Volunteers
- 112 people
- Sponsor
- University of Aarhus
Rectal Cancer
TaTME Versus Open Intersphincteric Resection After Neoadjuvant Concurrent Chemoradiotherapy.
The two surgical options for lower 1/3 rectal cancer is APR and sphincter sparing procedures. Intersphincteric resection is procedure to treat very low rectal cancer within 2 cm from the dentate line to avoid permanent…
- Trial name
- TaTME (NCT01836926)
- Testing
- Open intersphincteric resection, transanal minimally invasive intersphincteric resection
- Where
- 2 sites in Egypt
- Volunteers
- 110 people
- Sponsor
- Osama Mohammad Ali ElDamshety
Asthma, Chronic Obstructive Pulmonary Disease
Evaluation of the Efficacy of Respicure® (Resveratrol / Quercetin) in the Management of Respiratory Conditions Including Asthma,COPD and Long COVID.
Interventional, Prospective, National, Multicentre, Randomised, Open-label, Controlled Clinical Study Comparing Two Parallel Groups, One Control Arm (Standard Treatment) Versus Intervention Arm (Standard Treatment + Study…
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease, Long COVID
- Trial name
- NCT05601180
- Testing
- Respicure®, Standard of care
- Where
- 8 sites in Algeria
- Volunteers
- 402 people
- Sponsor
- Beker Laboratories
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