Clinical trials: Intervention Phase
End Stage Renal Disease
Fluid Overload in Peritoneal Dialysis
The objective of this study is to determine the effectiveness of treating peritoneal dialysis (PD) patients with fluid overload by a structured nurse-lead intervention protocol.
- Trial name
- NCT02557347
- Testing
- Aggressive fluid management
- Where
- Hong Kong
- Volunteers
- 102 people
- Sponsor
- Chinese University of Hong Kong
Breast Cancer
Mobile Phone Multimedia Messaging Intervention for Breast Cancer Screening
Korean American (KA) women have among the highest breast cancer mortality rates and lowest breast cancer screening rates of U.S. American women across racial/ethical groups.
- Trial name
- NCT01972048
- Testing
- mMammogram, Print brochure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Minnesota
Epidermolysis Bullosa
Allogeneic ABCB5-positive Dermal Mesenchymal Stromal Cells for Treatment of Epidermolysis Bullosa (Phase III, Cross-over)
The aim of this clinical trial is to investigate the safety and efficacy of allo-APZ2-OTS administered intravenously to subjects with recessive dystrophic epidermolysis bullosa (RDEB) compared to placebo.
- Trial name
- NCT05464381
- Testing
- allo-APZ2-OTS
- Where
- 16 sites in Argentina, Austria and 10 more
- Volunteers
- 91 people
- Sponsor
- RHEACELL GmbH & Co. KG
Non-small Cell Lung Cancer(NSCLC)
Bronchial Artery Chemoembolization (BACE) Combination Therapy for Advanced NSCLC
Patients with advanced non-small cell lung cancer (NSCLC) who experience disease progression after standard systemic therapies or are unable to tolerate such therapies have limited subsequent treatment options.
- Trial name
- NCT07738367
- Testing
- Bronchial Arterial Chemoembolization (BACE), Systemic anti-tumor combination medications
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Fujian Cancer Hospital
Non-Hodgkin Lymphoma, B-cell, Acute Lymphoblastic Leukemia ALL
A Study to Evaluate the Tolerability, Safety, and Efficacy of an Anti-CD19 CAR-T Product in Patients With B-cell Lymphoproliferative Disorders
This study is testing a new type of treatment called anti-CD19 CAR-T cell therapy for adults with certain blood cancers that have returned or did not respond to previous treatments.
- Trial name
- NCT06705530
- Testing
- Hem101
- Where
- Russia
- Volunteers
- 58 people
- Sponsor
- National Research Center for Hematology, Russia
Advanced Cancer, Neoplasms
The "Hand-in-Hand Study": Improvement of Quality of Life in Palliative Cancer Patients Through Collaborative Advance Care Planning
This study evaluates the effect of a collaborative advance care planning intervention on the quality of life in palliative oncological patients.
- Conditions
- Advanced Cancer, Neoplasms, End Stage Cancer
- Trial name
- COLAP (NCT03387436)
- Testing
- Study-Intervention
- Where
- 2 sites in Germany
- Volunteers
- 280 people
- Sponsor
- PD. Dr. med. Carola Seifart
Breast Cancer, Psychology, Social
Effectiveness of Screening and Brief Interventions for Alcohol and Tobacco During Breast Cancer Treatment (ONKODETOX)
Despite scientific, clinical and political incentives, alcohol and/or tobacco screening and brief intervention (SBI) services are poorly implemented in oncology settings.
- Trial name
- ONKODETOX (NCT03371732)
- Testing
- Motivational Intervention group, Educational advises group
- Where
- France
- Volunteers
- 104 people
- Sponsor
- Institut Bergonié
Local Advanced Non-small Cell Lung Cancer
Study of Early Nutritional Intervention During Concurrent Chemoradiotherapy for Local Advanced Non-small Cell Lung Cancer
This single-arm phase II prospective study is to determine the efficacy of early nutritional intervention during concurrent chemoradiotherapy for local advanced non-small cell lung cancer.
- Trial name
- NCT03673657
- Testing
- Early Nutrition Intervention from the start of CCRT, Thoracic radiotherapy, Weekly DP chemotherapy concurrent with thoracic radiotherapy
- Where
- China
- Volunteers
- 67 people
- Sponsor
- Sun Yat-sen University
Constipation
Efficacy and Safety of Prucalopride in Combination With Polyethylene Glycol or Lactulose in Women With Chronic Constipation
The purpose of this study is to evaluate the efficacy of prucalopride 2 mg, given orally once daily for 12 weeks, in combination with PEG or lactulose, in treatment of women with Chronic Constipation (CC) in whom laxatives fail…
- Trial name
- NCT02228616
- Testing
- Prucalopride, Polyethylene glycol (PEG), Lactulose
- Where
- 9 sites in China
- Volunteers
- 280 people
- Sponsor
- Xian-Janssen Pharmaceutical Ltd.
Epidermolysis Bullosa
Allogeneic ABCB5-positive Dermal Mesenchymal Stromal Cells for Treatment of Epidermolysis Bullosa (Phase III)
The aim of this clinical trial is to investigate the safety and efficacy of allo-APZ2-OTS administered intravenously to subjects with recessive dystrophic epidermolysis bullosa (RDEB) compared to placebo.
- Trial name
- NCT05838092
- Testing
- allo-APZ2-OTS
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- RHEACELL GmbH & Co. KG
Metastatic Breast Cancer, Toxicity
PAINTER: Polymorphism And INcidence of Toxicity in ERibulin Treatment
On March 17th, 2011, the European Commission issued a marketing authorization valid throughout the European Union for Eribulin mesylate (Halaven; Eisai Limited), for the treatment of patients with locally advanced or metastatic…
- Conditions
- Metastatic Breast Cancer, Toxicity, Neurotoxicity, Drug Toxicity
- Trial name
- NCT02864030
- Testing
- ERIBULIN MESYLATE
- Where
- 20 sites in Italy
- Volunteers
- 200 people
- Sponsor
- Oncologia Medica dell'Ospedale Fatebenefratelli
Infant, Premature, Diseases, Brain White Matter Disease Periventricular
Initial Efficacy Study of Supporting Play, Exploration, & Early Development Intervention
The primary aims of this randomized controlled trial are to evaluate efficacy potential of SPEEDI at enhancing reaching and play based problem solving compared to infants receiving usual care.
- Trial name
- SPEEDI (NCT02153736)
- Testing
- SPEEDI Intervention
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Virginia Commonwealth University
Colitis, Ulcerative
A Study to Investigate the Safety and Tolerability of Multiple Study Interventions in Participants With Moderate to Severe Ulcerative Colitis
This study will look at how safe and tolerable different treatments are for adults who have moderate to severe ulcerative colitis (UC).
- Trial name
- PEGASUS (NCT07747467)
- Testing
- Aletekitug (GSK1070806)
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- GlaxoSmithKline
Dementia, Mild Cognitive Impairment (MCI)
Early-Stage Partner in Care Living Alone Plus
EPICLA+ (Early-Stage Partners in Care Living Alone Plus) is a research project designed to assist people with early-stage memory loss who live alone in the community by providing early-stage related education and skill-training…
- Conditions
- Dementia, Mild Cognitive Impairment (MCI), Alzheimer Disease
- Trial name
- EPICLA+ (NCT06962111)
- Testing
- Psychoeducational skills training intervention
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Arizona State University
Adolescent, Bullying
Online Bullying Bystander Intervention for Middle Schools Phase II
School interventions to reduce bullying can be effective but also require substantial time and resources. Online technologies have the potential to deliver effective bullying interventions to a large number of middle school…
- Conditions
- Adolescent, Bullying, Technology, Mental Health
- Trial name
- STACII (NCT05572398)
- Testing
- STAC-T
- Where
- 2 sites in United States
- Volunteers
- 613 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
University Students, Psychological Well Being
Development of the Online Mindfulness-based Intervention (Mind Space Application) for Thai-university Students: Phase II
Development of the online mindfulness-based intervention (MFU-mindful Application for Thai university students: Phase II Objectives: Phase I: (October 2025 to September 2026) 1.
- Conditions
- University Students, Psychological Well Being, Mindfulness
- Trial name
- NCT07346612
- Testing
- mind space intervention
- Where
- Thailand
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Mae Fah Luang University
Non-small Cell Lung Cancer (NSCLC), Cachexia
A Study to Learn About the Study Medicine Called Ponsegromab in Adults With Lung Cancer-Associated Significant Body Weight Loss
Study to investigate the effect of ponsegromab on skeletal muscle mass and physical function in adult participants with non-small cell lung cancer associated cachexia.
- Trial name
- NCT07663630
- Testing
- ponsegromab
- Where
- 7 sites in United States, China
- Volunteers
- 80 people
- Sponsor
- Pfizer
Attention Deficit Hyperactivity Disorder, Oppositional Defiant Disorder
Home Based Treatment for Drug Use in Early Adolescents
This study will compare two programs to see if they are helpful in preventing the use of substances in adolescents with attention deficit-hyperactivity disorder (ADHD), oppositional defiant disorder (ODD), or conduct disorder…
- Conditions
- Attention Deficit Hyperactivity Disorder, Oppositional Defiant Disorder, Conduct Disorder, Substance Abuse
- Trial name
- NCT00280228
- Testing
- Adolescent Skills Parent Management Parent-Adol Negotiation, Treatment as Usual
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Pittsburgh
Lymphoma, Follicular
An Observational Study of MabThera/Rituxan (Rituximab) in Patients With Follicular Lymphoma
This observational study will evaluate the safety and efficacy of MabThera/Rituxan (rituximab) in previously untreated patients with follicular lymphoma. Data will be collected for 3 years
- Trial name
- NCT01609036
- Where
- 4 sites in Greece
- Volunteers
- 3 people
- Sponsor
- Hoffmann-La Roche
Fat Metabolism
Fatmax Exercise in Menstrual Phases: Effects on Fat Metabolism & Body Composition in NWO Women
Effects of a Fatmax exercise intervention during different menstrual phases on fat metabolism and body composition in NWO women
- Trial name
- NCT06961734
- Testing
- follicular group, luteal group, Control group
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.