Clinical trials: Interventional Study
Anxiety
Feasibility Study of a Music and Social Support Intervention for Postnatal Mothers/Infants
This research study aims to assess the feasibility of conducting a full scale trial of Mamas in Harmony, a group music and social support class delivered by a professional musician for mothers and their babies.
- Trial name
- NCT05930990
- Testing
- Mamas in Harmony
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Development
Neurodevelopmental Outcomes of Preterm Infants Treated for Pain Management With Repeated Doses of Sucrose 24%
The purpose of this study is to determine the effect of sucrose 24% for pain prevention on preterm infants. Our hypothesis is that repeated doses of sucrose 24%, given prior to painful procedure,do not impair neurodevelopmental…
- Trial name
- NCT01742520
- Testing
- multiple doses of sucrose, Formula or breast milk
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Intervention Study, Health Behavior
Effects of an mHealth Intervention to Improve Health Behaviors Among Sedentary Workers
Background: Studies have shown the negative impact of physical inactivity, sedentary and unhealthy eating behavior on worker health and productivity.
- Trial name
- NCT04347096
- Testing
- mHealth Intervention, Control Intervention
- Where
- Taiwan
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Percutaneous Coronary Intervention
3D Printed Silicone Coronary Artery Simulator for Percutaneous Coronary Interventional Training
This study is aim to evaluate the feasibility and effectiveness of 3D printed silicone coronary artery simulator for percutaneous coronary interventional training.
- Trial name
- 3DforPCI (NCT04420715)
- Testing
- Training on coronary angiography using 3D coronary artery simulator
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- China National Center for Cardiovascular Diseases
HSIL, High Grade Squamous Intraepithelial Lesion, CIN 2
Multicenter Prospective Non-randomized Controlled Study of Ella Photodynamic Therapy for Cervical HSIL/CIN2
This study evaluates the efficacy and safety of ALA-PDT versus LEEP in treating cervical HSIL/CIN2, aiming to demonstrate non-inferiority in clinical efficacy.
- Conditions
- HSIL, High Grade Squamous Intraepithelial Lesion, CIN 2, HPV (Human Papillomavirus)-Associated, Photodynamic Therapy (PDT)
- Trial name
- PDT for CIN2 (NCT07306260)
- Testing
- ALA-PDT, LEEP surgery
- Where
- 5 sites in China
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Opioid Use Disorder, Opioid Use Disorder, Moderate
Family-Focused Study to Support Medication for Opioid Use Disorder
The purpose of this clinical trial is to develop and test whether a text- and web-based tool called FamilyCHESS - designed for individuals with opioid use disorder (OUD) and a concerned significant other (CSO) - can help the…
- Conditions
- Opioid Use Disorder, Opioid Use Disorder, Moderate, Opioid Use Disorder, Severe
- Trial name
- NCT07451197
- Testing
- FamilyCHESS, Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Hand Hygiene, Skin Irritation
Evaluation of Effectiveness and Mildness of Whole-natural Hand-wash Formulations
The purpose of this study is to evaluate the effectiveness of whole-natural hand-wash formulations in bacterial removal and to estimate the relative mildness of the formulations.
- Trial name
- NCT02645110
- Testing
- MC Hand Soap, Tap water
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mother's Choice Ltd
Healthy Participants
A Trial Investigating Lu AF82422 in Healthy Chinese and Caucasian Adults
The main goals of this trial are to learn more about a) the safety and tolerability of Lu AF82422 (any new or worsening medical issues the participants have with treatment), b) the immunogenicity of Lu AF82422 (the potential for…
- Trial name
- NCT06258720
- Testing
- Lu AF82422
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Healthy
Randomized, Controlled Study to Compare Straumann® VivOss™ to Geistlich Bio-Oss® in Sinus Floor Augmentation.
A randomized controlled clinical trial to investigate the capability of Straumann® VivOss™ compared to Geistlich Bio-Oss in sinus floor augmentation to demonstrate superiority of Straumann® VivOss™ compared to Geistlich Bio-Oss…
- Trial name
- NCT02288182
- Testing
- Straumann VivOss, Geistlich Bio-Oss
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Institut Straumann AG
Inhibition (Psychology), Updating
Attentional Control Training in Older Adults: Efficacy, Transfer and Brain Substrates
Formal education and cognitively stimulating hobbies and profession have a protective effect against age-related cognitive decline and Alzheimer's disease.
- Conditions
- Inhibition (Psychology), Updating, General Knowledge, No Training
- Trial name
- NCT03532113
- Testing
- Updating, Inhibition, General knowledge
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Covid19
Efficacy and Safety of Liposomal Lactoferrin in COVID-19 Patients With Mild-to-Moderate Disease and in COVID-19 Asymptomatic Patients
COVID-19 is considered an ongoing international global health problem which already caused 12 million confirmed cases. No specific effective treatment has been identified so far, and available supportive therapies are intended…
- Trial name
- NCT04475120
- Testing
- liposomal lactoferrin, SOC therapy
- Where
- Italy
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Rome Tor Vergata
Executive Function Disorder, Emotional Regulation
Evaluation of Executive Function and Emotional Regulation in Children in Bangladesh
The study explores the impact of malnutrition at enrollment on executive function (EF) and emotional regulation (ER) in malnourished 1-year-old children and whether specially designed brain directed therapeutic feeds improve…
- Conditions
- Executive Function Disorder, Emotional Regulation, Malnutrition, Child
- Trial name
- NCT05629624
- Testing
- Chickpea based RUSF, E-RUSF, Outcome reference group/RUSF
- Where
- Bangladesh
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Healthy Participants
A Study to Learn If the Study Medicine Called Vepdegestrant Changes How the Body Processes the Other Study Medicine Called Midazolam
The purpose of this study is to learn if the study medicine called Vepdegestrant changes how the body processes the other study medicine called Midazolam. This study is seeking participants who: female who cannot have children.
- Trial name
- NCT06256510
- Testing
- Midazolam, Vepdegestrant
- Where
- Belgium
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Pfizer
Patient Compliance
Human Papilloma Viruses (HPV) Vaccine Adherence Community Clinic Study
There has been very limited research that has looked at electronic reminders (text messages) and its effectiveness in adherence to vaccination among low-income minority populations.
- Trial name
- NCT01908517
- Testing
- HPV Vaccine Electronic Reminders
- Where
- 2 sites in United States
- Volunteers
- 522 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Neonatal Resuscitation, Heart Rate Assessment
Impact of a Mobile Application for Heart Rate Assessment in Simulated Neonatal Resuscitation
NeoTapAdvancedSupport (NeoTapAS) is a free-of-charge mobile application that showed good accuracy in HR estimation. This study aims to evaluate the impact of NeoTapAS on timing of HR communication and of resuscitation…
- Trial name
- NCT03730025
- Testing
- Auscultation plus NeoTapAS, Auscultation without NeoTapAS
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital Padova
Cancer
Selenium in the Prevention of Cancer
This is a pilot study proceeding an intended international trial. Hypothesis: Daily intake of selenium supplementation in the form of selenium-enriched yeast tablets will reduce the risk of cancer in healthy individuals.
- Trial name
- DK PRECISE (NCT01819649)
- Testing
- SelenoPRECISE selenium-enriched yeast tablet, Pharma Nord Denmark A/S
- Where
- Denmark
- Volunteers
- 491 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Periodontitis, Chronic Periodontitis (Disorder)
Cofilin-2 (rs80358250) and Lactoferrin (rs1126478) Polymorphism and Protein Levels With Non Surgical Periodontal Therapy in Periodontitis Patients With and Without CHD
Periodontitis is a chronic multifactorial inflammatory disease associated with the accumulation of dental plaque and characterized by progressive destruction of the teeth-supporting apparatus, including the periodontal ligament…
- Conditions
- Periodontitis, Chronic Periodontitis (Disorder), Coronary Heart Disease
- Trial name
- NCT07353606
- Testing
- Scaling and root planing
- Where
- 2 sites in India
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Meenakshi Ammal Dental College and Hospital
Obesity
Puberty Related Intervention to Improve Metabolic Outcomes (The PRIMO Study)
Puberty represents a critical period in terms of metabolic health. Racial differences in insulin dynamics, reproductive maturation, and the associated endocrine changes may affect a female's health later in life.
- Trial name
- PRIMO (NCT01410643)
- Testing
- Macronutrient Modification
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
25-hydroxyvitamin D Concentration (Vitamin D Status)
D-Light Intervention
Vitamin D insufficiency has become a global concern, with low vitamin D status associated with bone disorders, cardiovascular disease and certain cancers.
- Trial name
- D-Light (NCT02495584)
- Testing
- Fortified milk (10µg vitamin D3), 10µg vitamin D3 supplement
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Metabolic Control
The NUTRIOME Study - a Data-driven Precision Nutrition Intervention
The overall objective of this multi-center study is to use metabolic response data from different dietary challenges to develop personalized dietary advice.
- Trial name
- NUTRIOME (NCT06842433)
- Testing
- General healthy diet, Personalized diet
- Where
- 3 sites in Netherlands, Norway and 1 more
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chalmers University of Technology