Clinical trials: Interventions
Physiotherapy and Rehabilitation, Educational Technology
Flipped Classroom vs. Flip-Jigsaw in Theoretical Physiotherapy Education
Study Summary: This quasi-experimental pre-test-post-test study aims to compare the effects of Flipped Classroom (FC) and Flip-Jigsaw instructional models on theoretical knowledge acquisition, academic motivation, and class…
- Conditions
- Physiotherapy and Rehabilitation, Educational Technology, Educational Interventions, Students
- Trial name
- NCT06950918
- Testing
- Experimental
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Isparta University of Applied Sciences
Neonatal Palliative Care, Educational Intervention for NICU Nursing Performance
Effect of an Educational Program on Neonatal Intensive Care Nurses' Performance Regarding Neonatal Palliative Care in Egypt.
This quasi-experimental study aims to evaluate the effect of an educational program on neonatal intensive care unit (NICU) nurses' performance regarding neonatal palliative care.
- Trial name
- NCT07902557
- Testing
- Neonatal Palliative Care Educational Program
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Asmaa Rashad
Percutaneous Coronary Intervention, Peripheral Endovascular Intervention
Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention
V-INTERVENTION will evaluate the effectiveness of inclisiran in preventing major cardiovascular and limb events in patients receiving percutaneous coronary or peripheral arterial revascularization.
- Trial name
- V-INTERVENTION (NCT06909565)
- Testing
- Inclisiran sodium 300 mg (equivalent to 284 mg inclisiran) in 1.5 mL
- Where
- 149 sites in United States
- Volunteers
- 6,000 people
- Sponsor
- Duke University
AI-CBT Intervention Group, Waitlist Control Group
AI-Based CBT Chatbot for Adolescent Social Anxiety
The goal of this clinical trial is to learn if a CBT-based AI chatbot works to reduce social anxiety in teenagers. It will also look at how the chatbot works, including changes in thinking patterns, emotion management, and safety…
- Trial name
- NCT07897084
- Testing
- AI-CBT intervention group
- Volunteers
- 120 people
- Sponsor
- Central China Normal University
Healthy, College Students
Testing the Feasibility and Impact of a Whole-Food Plant-Based Diet Intervention on College Students
The goal of this pilot randomized controlled trial (RCT) was to assess the feasibility, acceptability, and impacts of a whole-food plant-based (WFPB) vegan diet intervention for undergraduate university students randomly…
- Conditions
- Healthy, College Students, Diet Interventions, Vegan Diet
- Trial name
- NCT07903935
- Testing
- Interactive intervention group, Lecture-based intervention
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Palliative Care, Health Services, Palliative Care
Integrating Rhythmical Massage in Palliative Care
People receiving palliative and end-of-life care may experience pain, fatigue, sleep difficulties, anxiety, and other symptoms that affect their comfort and quality of life.
- Conditions
- Palliative Care, Health Services, Palliative Care, Massage Intervention
- Trial name
- NCT07904611
- Testing
- Rhythmic Massage
- Volunteers
- 70 people
- Sponsor
- Monash University Malaysia
Peer Bullying Intervention, Vodcast
Early Detection and Kinetics of Sepsis-Induced Coagulopathy in Severe Burn Patients
The purpose of this study is to evaluate the impact of an avatar-supported, teacher-student interactive, vodcast-based peer bullying prevention program-developed for adolescents-on students' ability to identify peer bullying…
- Conditions
- Peer Bullying Intervention, Vodcast, Students
- Trial name
- SIC-BURN-JAAM2 (NCT07905807)
- Testing
- Vodcast-Based Peer Bullying Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Chirurgical Intervention, Thrombocytopaenia
Preoperative Use of Romiplostim in Thrombocytopenic Patients Undergoing Cardiac Surgery.
Romiplostim has demonstrated its efficacy and good tolerance in multiple indications. If the efficacy of Romiplostim is confirmed in this population, thrombocytopenic patients will be able to undergo cardiac surgery, which is…
- Trial name
- CT-PLATE (NCT07278661)
- Testing
- Nplate, NaCl %0.9
- Where
- 8 sites in France
- Volunteers
- 142 people
- Sponsor
- Nantes University Hospital
Breast Cancer, Caregiver
The Effect of Dyadic Self-Care Education Provided to Breast Cancer Patient-Caregiver Dyads on Patient and Caregiver Outcomes
This randomized controlled trial aims to evaluate the effect of dyadic self-care education provided to breast cancer patient-caregiver dyads receiving outpatient chemotherapy on patient self-care behaviors, anxiety levels, and…
- Conditions
- Breast Cancer, Caregiver, Caregiver Anxiety, Self Care
- Trial name
- NCT07742969
- Testing
- Dyadic Self Care Education
- Where
- Turkey (Türkiye)
- Volunteers
- 192 people
- Sponsor
- Ulviye Aydan NACAK
Postpartum Depression (PPD), Web-based Intervention
A Web-based Intervention Program for Postpartum Depression
This study evaluates a Web-based intervention program to treat women with postpartum depression.
- Trial name
- NCT07902141
- Testing
- Web-based program for postpartum depression
- Where
- Romania
- Volunteers
- 30 people
- Sponsor
- Babes-Bolyai University
Menstrual Regulation, Menstrual Health Intervention
Period Pills for Menstrual Regulation: A New Reproductive Health Option
The Period Pills Study is a prospective observational study among people who decide to use a combination of mifepristone and misoprostol for menstrual regulation.
- Trial name
- Period Pills (NCT07671989)
- Testing
- Mifepristone + Misoprostol
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Evaluation Studies, Implementation Research
Implementation of the Begin Exploring Fertility Options, Risks and Expectations (BEFORE) Decision Aid
The Begin Exploring Fertility Options, Risks and Expectations (BEFORE) decision aid was created to support fertility discussions and decision-making for young breast cancer patients in Canada.
- Conditions
- Evaluation Studies, Implementation Research, Decision Aid, Young Adult Cancer
- Trial name
- BEFORE (NCT03629509)
- Testing
- Educational Webinar and Resources
- Where
- Canada
- Volunteers
- 116 people
- Sponsor
- Unity Health Toronto
Intervention
Effect of Developmental Care on Very Low Birth Weight Infants
The goal of this clinical trial is to learn if developmental care works when implemented in very low birth weight infants. The main questions it aims to answer are: Does developmental care shorten the length of hospital stay in…
- Trial name
- NCT06515574
- Testing
- developmental care
- Where
- 2 sites in China
- Volunteers
- 1,600 people
- Sponsor
- Children's Hospital of Fudan University
mERAS Intervention, The ASA (American Society of Anesthesiologists) Score
The Contribution of Accelerated Recovery (mERAS) Approach to Postoperative Recovery in Pediatric Laparoscopic Surgery Cases
Pediatric laparoscopic surgery is a gold standard across all ages, offering benefits like smaller incisions, faster recovery, and better cosmetic outcomes.
- Conditions
- mERAS Intervention, The ASA (American Society of Anesthesiologists) Score, The Patient Must be Between 4 and 12 Years Old
- Trial name
- Accelerated Re (NCT07375511)
- Testing
- mERAS Protocol
- Volunteers
- 60 people
- Sponsor
- Emel Yürük
Constipation, Probiotic
Multi-strain Probiotic Effects on Self-Reported Constipation
Constipation is a prevalent gastrointestinal condition. Beyond simple lifestyle measures (e.g. increasing fibre intake, hydration, levels of exercise), medical therapies are available for management.
- Conditions
- Constipation, Probiotic, Probiotic Intervention
- Trial name
- NCT07275866
- Testing
- Multi-strain probiotics
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Dr Anthony Hobson
Type 1 Diabetes, Continuous Glucose Monitoring
Research on Optimizing the Use of Technology With Education
Consistent use of continuous glucose monitors (CGM) has the potential to improve glycemic control and related type 1 diabetes (T1D) health outcomes, however young adolescents with T1D are the least likely age group to begin and…
- Conditions
- Type 1 Diabetes, Continuous Glucose Monitoring, Behavioral Intervention, Parent-Child Relations
- Trial name
- ROUTE-T1D (NCT05564481)
- Testing
- diabetes education and parent coaching support
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's National Research Institute
Ischemia, Myocardial, Coronary Artery Disease
Comparison of an Ultra-low Strut Thickness Everolimus-eluting Biodegradable Polymer Stent Versus Durable Polymer Everolimus-eluting Stents in Patients Treated With Percutaneous Coronary Intervention
The objective of this randomized study is to compare the safety and efficacy of the ultra-low strut thickness everolimus-eluting biodegradable polymer Evermine50 stent to the everolimus-eluting family stents (durable polymer…
- Conditions
- Ischemia, Myocardial, Coronary Artery Disease, Percutaneous Coronary Intervention (PCI)
- Trial name
- SORT OUT XII (NCT06692140)
- Testing
- Ultra-low strut thickness everolimus-eluting biodegradable polymer Evermine50 stent(s), PCI with Everolimus-eluting stents (durable polymer everolimus-eluting Xience or Promus stent(s))
- Where
- 3 sites in Denmark
- Volunteers
- 3,150 people
- Sponsor
- Odense University Hospital
Depression, Anxiety, Intervention
'Nurture and Play' - a Pilot Study
The aim of this randomised controlled pilot study is to evaluate the feasibility of the Nurture and Play (NnP) offered to a Danish population of psychosocial vulnerable pregnant women and their partners.
- Conditions
- Depression, Anxiety, Intervention, Randomized Controlled Study
- Trial name
- NCT06791876
- Testing
- Nurture and Play (NnP)
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Center for Clinical Research and Prevention
Pneumococcal Infections, Immunization Programs
Randomized Controlled Trial Of Text Messages To Increase Pneumococcal Vaccination In Adults In Chile.
The goal of this randomized controlled trial is to learn if text message reminders sent through WhatsApp increase pneumococcal vaccination coverage in adults turning 65 years old in Chile.
- Conditions
- Pneumococcal Infections, Immunization Programs, Vaccination Coverage, Text Messaging (Intervention)
- Trial name
- PNEUMO-SMS (NCT07659470)
- Testing
- WhatsApp text message reminder for pneumococcal vaccination
- Where
- Chile
- Volunteers
- 40,753 people, healthy volunteers welcome
- Sponsor
- Pablo Tomás Valenzuela García
Obesity & Overweight, Childhood
Project GAME ON! A Digital Comic Tool to Promote Healthy Behaviors
This clinical trial aims to evaluate an interactive, culturally relevant digital health promotion comic designed to support healthy dietary and physical activity behaviors among Black/African American and Latino children ages 8…
- Conditions
- Obesity & Overweight, Childhood, Diet Habits, Engagement
- Trial name
- NCT07820735
- Testing
- Web-based customizable comic and newsletters, Didactic health information and newsletters, Web-based comic and newsletters
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Tufts University