Clinical trials: Interventions
Breast Cancer, Alcohol Drinking
Implementing a Digital Alcohol Intervention to Raise Women's Awareness of Alcohol-related Breast Cancer Risk During Routine Screening Visits
This study is a single-arm feasibility trial evaluating a digital behavioral intervention designed to increase women's awareness of the relationship between alcohol use and breast cancer risk during routine breast cancer…
- Trial name
- NCT07799467
- Testing
- Sobriety Digital Intervention
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Miami
Peripheral Artery Disease
Low InTensity Exercise Intervention in PAD
This proposed study will determine whether a home-based exercise intervention that avoids continuous supervision and exercise-related ischemic pain improves walking performance at 52-week follow-up in people with PAD, compared to…
- Trial name
- LITE (NCT02538900)
- Testing
- Exercise, Attention control
- Where
- 4 sites in United States
- Volunteers
- 305 people
- Sponsor
- Northwestern University
ADHD, Attention Deficit Disorder With Hyperactivity
RCT, Proof of Concept Study of TEAMS (Training Executive, Attention and Motor Skills) Intervention Program
Background: TEAMS (Training Executive Attention and Motor Skills) is a non-pharmacological, neurocognitive intervention program targeted preschool children with ADHD developed by Professor Jeffrey Halperin, and his team from New…
- Trial name
- TEAMS (NCT01918436)
- Testing
- TEAMS intervention, Control group
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- Holbaek Sygehus
Taking Benzodiazepines for Any Reason for 3 Months, Benzodiazepine Dependence
Promoting Benzodiazepine Cessation Through an Electronically-delivered Patient Self-management Intervention
Benzodiazepines (e.g., Ativan, Xanax) are widely prescribed medications that are used mainly to treat anxiety and sleeping difficulties.
- Trial name
- EMPOWER-ED (NCT04572750)
- Testing
- EMPOWER-ED
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- VA Office of Research and Development
Skin and Subcutaneous Tissue Bacterial Infections, Staphylococcus Aureus
Staph Household Intervention for Eradication (SHINE)
The investigators propose a pragmatic comparative effectiveness trial evaluating several decolonization strategies in patients with Staphylococcus aureus infection, their household contacts, and household environmental surfaces.
- Conditions
- Skin and Subcutaneous Tissue Bacterial Infections, Staphylococcus Aureus, MRSA - Methicillin Resistant Staphylococcus Aureus Infection
- Trial name
- SHINE (NCT02572791)
- Testing
- Chlorhexidine, Mupirocin, Household cleaning
- Where
- 2 sites in United States
- Volunteers
- 835 people
- Sponsor
- Washington University School of Medicine
Peripheral Neuropathy
Evaluation of an Exercise Intervention for Vincristine Induced Peripheral Neuropathy in Pediatric Cancer Patients
The purpose of this study is to better understand whether or not children with ALL can complete an exercise program during treatment and whether or not that program may impact peripheral neuropathy.
- Trial name
- Exercise (NCT03430674)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Indiana University
Mania (Neurotic)
A Probiotic Intervention to Prevent Relapse Following Hospitalization for Mania
This will be a 24-week, randomized, double-blind, placebo-controlled trial of adjunctive probiotic therapy in 66 persons hospitalized with a manic or mixed episode.
- Trial name
- NCT03383874
- Testing
- Probio-Tec BG-VCap-6.5
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of Texas Southwestern Medical Center
Atrial Fibrillation
The Norwegian Exercise in Atrial Fibrillation Trial
Atrial fibrillation (AF) patients suffer a high symptom burden and reduced quality of life (QoL), high hospitalization rates and few effective treatment options. They have a high burden of cardiovascular risk factors and events.
- Trial name
- NEXAF (NCT05164718)
- Testing
- Supervised home-based exercise, Usual care
- Where
- 3 sites in Norway
- Volunteers
- 300 people
- Sponsor
- Norwegian University of Science and Technology
Microbiome Composition, Microbiome
The Effects of an Oral Nutritional Intervention on the Small Intestine Microbiome
This is a single-center, single-arm study, aiming at enrolling 25 healthy adult participants to evaluate chronic effects of oil. Specifically, we aim to assess the impact on gut microbiome after a one-month intervention with oil.
- Trial name
- NCT07439718
- Testing
- Oil
- Where
- Switzerland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Cigarette Smoking, Current Smoker
Quit4Health Intervention in Supporting Smoking Cessation and Preventing Smoking Initiation in Young Adults
This trial studies how well Quit4Health intervention works in supporting smoking cessation and preventing smoking initiation in young adults.
- Trial name
- NCT04009590
- Testing
- Educational Intervention, Questionnaire Administration, Smoking Cessation Intervention
- Where
- United States
- Volunteers
- 579 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Anxiety, Digital Eye Strain
Reducing Eye Strain and Anxiety Using a Digital Intervention During Online Learning Class Recess Among Children at Home: A Randomized Controlled Trial
The primary aim of the current study is to conduct a cluster-randomized control trial to evaluate the effectiveness of a novel digital intervention in reducing anxiety and digital eye strain compared to usual care among Chinese…
- Trial name
- RESILIENT (NCT04309097)
- Testing
- Digital intervention, Information-only intervention
- Where
- China
- Volunteers
- 954 people
- Sponsor
- Sun Yat-sen University
Depression, Sleep Disorders, Circadian Rhythm
Sleep-Wake Patterns on Illness Trajectories and Treatment Response in MDD
The proposed study will include a longitudinal ecological study (Study 1) and a randomised controlled trial (Study 2). The aims will be to (1) identify the sleep-wake profiles in individuals with MDD through clustering; (2)…
- Trial name
- NCT06181110
- Testing
- Transdiagnostic Intervention for Sleep and Circadian Dysfunction
- Where
- Hong Kong
- Volunteers
- 70 people
- Sponsor
- Chinese University of Hong Kong
Percutaneous Coronary Intervention, Dual Antiplatelet Therapy
Efficacy and Safety of Short Duration of DAPT After GENOSS® DES Implantation in Patients with Coronary Artery Disease
The objective of study is to evaluate the efficacy and safety of short duration of DAPT after GENOSS® DES Implantation in patients with coronary artery disease.
- Trial name
- DAPTShort (NCT06075420)
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Genoss Co., Ltd.
E-cigarette Use
Vape-Free Text-Messaging: Pilot Study
This is a small pilot randomized controlled trial to evaluate the feasibility, acceptability, and preliminary efficacy of the e-cigarette cessation text-messaging intervention with young adults in rural areas.
- Trial name
- NCT05906082
- Testing
- E-cigarette cessation text-messaging intervention, Standard care control using standard national resources
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jovan Gwon, PhD, RN, FIAAN
Urothelial Carcinoma
The Cxbladder Monitoring Study
The aim of this trial is to determine the performance characteristics of the Cxbladder test for the detection of recurrent urothelial carcinoma (UC) in patients with a recent history of urinary tract UC, who have been treated…
- Trial name
- NCT02700659
- Testing
- Cxbladder
- Where
- 11 sites in United States
- Volunteers
- 803 people
- Sponsor
- Pacific Edge Limited
Trauma Injury
Developing a Deliberate Practice Intervention to Recalibrate Physician Heuristics in Trauma Triage
The objective of this study is to test the feasibility of using deliberate practice - goal-oriented training in the presence of a coach who can provide personalized, immediate feedback - to increase engagement.
- Trial name
- NCT05168579
- Testing
- Deliberate practice
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Pressure Injury
Virtual Reality and AI Wound-detecting System
This study is an experimental study. The main caregivers of pressure injury patients in the plastics surgery ward and general medicine ward of the hospital in Taipei City who are over 20 years old, have good communication skills…
- Trial name
- NCT06367179
- Testing
- Virtual reality and AI use, Health education leaflet
- Where
- Taiwan
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Ischemic Stroke
Affect of Health Education on Statins Medication Persistence and ClinicaL Prognosis of Ischemic Stroke Patients (HELP)
The purpose of this study is to assess the affect of multiple health education interventions for statins medication Persistence and clinical prognosis of ischemic stroke patients at 3, 6 and 12 months.
- Trial name
- NCT02140658
- Testing
- multiple health education interventions, conventional health education
- Where
- China
- Volunteers
- 3,111 people
- Sponsor
- yongjun wang
Dental Anxiety
Efficacy of an Internet-based Intervention for Dental Anxiety
The overall objective of the activities described in this protocol is to examine the efficacy of the Internet-based intervention in the reduction of dental anxiety in patients seeking dental treatment.
- Trial name
- NCT03680755
- Testing
- Internet-based intervention for dental anxiety
- Where
- United States
- Volunteers
- 503 people
- Sponsor
- Temple University
Anxiety Disorder of Childhood, Fear
Addressing Anxiety in 2-3-Year-Olds: A Pilot Intervention Study
The purpose of this study is to test the feasibility and efficacy of intervening with 2-year-old children with elevated temperamental Fear and/or Shyness or 3-year-old children with elevated anxiety and their parents, using a…
- Conditions
- Anxiety Disorder of Childhood, Fear, Shyness
- Trial name
- NCT04039243
- Testing
- Being Brave, Parent Education
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
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