Clinical trials: Interventions
Depressive Symptoms, Substance-related Disorders
Intervention for Veterans With Depression, Substance Disorder, and Trauma
This study will compare two different types of psychotherapy for Veterans with depression, addiction, and a past traumatic experience.
- Conditions
- Depressive Symptoms, Substance-related Disorders, Posttraumatic Stress Disorders
- Trial name
- NCT00958217
- Testing
- Cognitive Processing Therapy-Modified (CPT-M), Integrated Cognitive Behavioral Therapy (ICBT)
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- VA Office of Research and Development
Vaccine Refusal
Promoting Altruism to Enhance Vaccine Acceptance
Subjects enrolled in this study are eligible for the seasonal influenza vaccine. The purpose of this research study is to figure out if increasing individuals' awareness of the benefits of herd immunity, specifically to the local…
- Trial name
- NCT04568590
- Testing
- educational intervention
- Where
- United States
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
AIDS/HIV
Smoking Cessation Intervention for Women Living With HIV
As people with HIV/AIDS live longer, the burden of non-AIDS-related health problems such as cardiovascular diseases and cancers on these people have consistently increased.
- Trial name
- SoCIWHIV (NCT02898597)
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of Massachusetts, Boston
Coronary Artery Disease
The Cardiac Benefit of Testosterone Replacement in Men With Low Testosterone Levels With Coronary Artery Disease After Successful Intervention of the Blockage or Narrowed Heart Artery
The purpose of the study is to find out if giving the study drug, Androgel (testosterone) as a testosterone replacement help bring the testosterone to an acceptable level and to find out if it will help improve heart condition in…
- Trial name
- NCT00413244
- Testing
- AndroGel 5 Grams
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hypertension, Metabolic Disorder
The Effects of Obstructive Sleep Apnea and Its Intervention on Coronary Heart Disease
Obstructive sleep apnea(OSA) is an important identifiable cause of hypertension. Previous study has suggested that OSA significantly increases cardiovascular morbidity and mortality, especially in patients with pre-existing…
- Trial name
- NCT02059993
- Testing
- continuous positive airway pressure
- Volunteers
- 83 people
- Sponsor
- Chinese Pulmonary Vascular Disease Research Group
Tennis Elbow, Epicondylitis, Lateral Humeral
Treatment Study of Steroid Injection and Physical Therapy for Acute Lateral Epicondylitis
The purpose of this study is to compare the clinical effect of physiotherapy alone or combined with corticosteroid injection in the initial treatment of lateral epicondylitis in a primary care setting.
- Trial name
- NCT00826462
- Testing
- triamcinolone, Lidocaine, Physiotherapy
- Where
- Norway
- Volunteers
- 177 people
- Sponsor
- University of Oslo
Atrial Fibrillation
Dabigatran Adherence Pilot Intervention for Patients With Atrial Fibrillation
Atrial fibrillation is common and increases the risk of clotting especially in patients with multiple clotting risk factors. Patients treated with warfarin, an oral anti-coagulant, require frequent lab monitoring and dose…
- Trial name
- NCT01578044
- Testing
- Intervention, Control
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
HIV, AIDS
Care4Today v2.0 Application for Improving Adherence to HIV Medications
Although poor antiretroviral (ART) adherence in HIV does not mean a complete lack of therapeutic results, the benefit of ART increases as adherence improves.
- Trial name
- NCT02001064
- Testing
- Care4Today v2.0 mobile application + electronic monitoring of adherence
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Diego
Novice Teen Driver Training
An Evaluation of a Web-based Intervention Program for Parents and Teens to Promote Safe Driving
The long-term goal of this research is to increase safe driving among novice teen drivers by increasing the quantity, quality and diversity of driving practice while accompanied by an adult.
- Trial name
- NCT01498575
- Testing
- Teen driving plan
- Where
- United States
- Volunteers
- 1,024 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Trauma, Hiv
Developing a Trauma-focused Intervention for Older Adults Living With HIV
Investigators are adapting the LIFT and REFLECT interventions for older adults living with HIV who have been exposed to childhood sexual abuse.
- Conditions
- Trauma, Hiv, Aging
- Trial name
- NCT05287230
- Testing
- CoSHA (Coping with childhood Sexual Abuse, HIV, and Aging), Control
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of South Carolina
Human Immunodeficiency Virus, Cardiometabolic Risk
The Happy Older Latinos Are Active (HOLA) Health Promotion Study in HIV-Infected Latino Men
The purpose of this study is to examine the feasibility of an intervention to prevent chronic diseases like diabetes, high blood pressure, and obesity in midlife and older Latino adults living with HIV.
- Trial name
- HOLAHIV (NCT03839212)
- Testing
- HOLA Component 1, HOLA Component 2, HOLA Component 3
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Miami
Cancer of the Head and Neck
A Web-Based Multimedia Intervention for Head and Neck Cancer Patients
The overall goal is to develop and examine the acceptability of a web-based (Internet) intervention program for patients with head and neck cancer who have recently completed radiation therapy.
- Trial name
- NCT02442336
- Testing
- My Journey AHead
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Fox Chase Cancer Center
Anticoagulants
Efficacy of a Health Belief Model Based Intervention for Anticoagulation Adherence
Inconsistent anticoagulation therapy in AF patients is associated with a higher risk of stroke and abnormal bleeding. The purpose of the study is to investigate the efficacy of a health belief model based self-management of oral…
- Trial name
- NCT03864900
- Testing
- The medication adherence intervention
- Where
- 2 sites in Taiwan
- Volunteers
- 72 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Substance Use, Psychopathy
The Impact of Psychopathic Traits on the Efficacy of a Substance Use Intervention
Substance use among criminal offenders constitutes a major public health problem and is tied to negative consequences for offenders, their families, and their communities.
- Trial name
- NCT01532934
- Testing
- motivational enhancement therapy, standard care
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- University of Rochester
Diabetes Mellitus, Type 2, Substance-related Disorders
Screening, Brief Intervention, and Referral to Treatment in Primary Care
This add-on study of providing tobacco, alcohol and other drug screening, brief intervention and referral for treatment to a primary care high risk diabetic population leverages the existing research resources of a funded parent…
- Trial name
- SBIRT-PC (NCT01966432)
- Testing
- Referral to Treatment, Brief Intervention
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Duke University
Binge-Eating Disorder
Acceptance-based Group Intervention for Binge Eating
This study proposes to compare a brief Acceptance and Commitment Therapy (ACT) group intervention to an active control group in a sample of 154 overweight or obese binge eating Veterans who have completed the VA's national…
- Trial name
- NCT01757847
- Testing
- Acceptance and Commitment Therapy (ACT), Brief MOVE-II control group intervention
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- VA Office of Research and Development
Coronary Heart Disease, Cardiac Rehabilitation
Reducing Risk in Cardiac Rehabilitation: Partners Together in Health (PaTH) Intervention Study
The objective of the proposed study, using an experimental, two-group (n = 30 couples in each group) repeated measures design, was to pilot test the effects of the PaTH Intervention versus a usual care group in improving the…
- Trial name
- PaTH (NCT00926848)
- Testing
- Partners Together in Health (PaTH) Intervention
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Chronic Pain, Obesity
A Mobile Intervention to Reduce Pain and Improve Health (MORPH)
Chronic pain contributes to declining health and function in older adults; effects that are intensified by obesity and sedentary (sitting) behavior.
- Conditions
- Chronic Pain, Obesity, Sedentary Lifestyle
- Trial name
- NCT03377634
- Testing
- MORPH
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Wake Forest University Health Sciences
Atopic Dermatitis
Safety and Efficacy of Pimecrolimus Cream 1% in Atopic Disease Modification
This study consists of a 3-year double-blind phase during which patients will receive atopic dermatitis (AD) treatment either with pimecrolimus cream 1% long-term management (LTM) or with a conventional corticosteroid-based…
- Trial name
- NCT00124709
- Testing
- Pimecrolimus, Corticosteroid
- Where
- 36 sites in United States
- Volunteers
- 1,091 people
- Sponsor
- Novartis Pharmaceuticals
Bacterial Infection
Efficacy and Safety of Ceftaroline Versus Linezolid in Subjects With Complicated Skin and Skin Structure Infections
The purpose of this study is to determine whether ceftaroline is effective and safe in the treatment of complicated skin and skin structure infections in adults.
- Trial name
- NCT00633152
- Testing
- ceftaroline, linezolid, Aztreonam
- Where
- 13 sites in United States
- Volunteers
- 150 people
- Sponsor
- Forest Laboratories
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