Clinical trials: Interventions
Lung Cancer
A Patient and Provider Intervention to Address Health Disparities in Lung Cancer Screening
To test the impact of a multilevel intervention on primary (provider-patient communication, intentions, and knowledge) and secondary (screening referrals and completion) outcomes.
- Trial name
- NCT04675476
- Testing
- Provider Prompt & Patient Outreach and Education
- Where
- United States
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Abnormal Glucose Metabolism
Abnormal Glucose Metabolism in HIV-infected Patients
HIV is a major health problem worldwide especially in low-to middle-income countries including Thailand. Fortunately, a significant reduction in morbidity and mortality has been observed due to the use of combination…
- Trial name
- NCT03545217
- Testing
- Lifestyle Intervention
- Where
- Thailand
- Volunteers
- 75 people
- Sponsor
- Mahidol University
Chronic Nonspecific Low Back Pain
The Influence of an Educational Intervention in the Beliefs and Attitudes of Primary Care Professionals
Aim: The primary aim of this project is to identify the fear-avoidance beliefs and attitudes of primary care physicians and nurses towards the treatment of chronic nonspecific low back pain to subsequently develop a…
- Trial name
- NCT02962817
- Testing
- Educational intervention, Video explaining the clinical practice guidelines on low back pain
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Universitat de Lleida
Obesity, Overweight
PILI at Work a 5-Year Controlled Intervention Trial: Testing DVD Versus Group Delivery of a Weight-Loss Maintenance Intervention in Native Hawaiian- Serving Worksites
The PILI @ Work project is a 5 year randomized control trial to adapt a weight loss program for the employees of Native Hawaiian-serving organizations in Hawai'i.
- Conditions
- Obesity, Overweight, Weight Loss, Weight Loss Maintenance
- Trial name
- P@W (NCT01652989)
- Testing
- Weight loss maintenance intervention face-to-face, Weight loss maintenance intervention delivered via DVD
- Where
- 8 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Hawaii
HIV
Phase II Randomised Controlled Trial of Memory Work Therapy at PASADA, Tanzania
Memory Work Therapy (MWT) has been developed to improve psycho-social outcomes for children living with HIV who are orphaned. This phase 2 trial aims to determine whether attending the intervention improves outcomes compared to…
- Trial name
- MWT (NCT02180750)
- Testing
- Memory Work Therapy, Standard care
- Where
- Tanzania
- Volunteers
- 48 people
- Sponsor
- Pastoral Activities and Service for AIDS Dar-Es-Salaam Archdiocese
Elder Mistreatment, Elder Abuse
Knowledge and Interpersonal Skills to Develop Enhanced Relationships (KINDER)
The Knowledge and Interpersonal Skills to Develop Enhanced Relationships (KINDER) intervention was developed to prevent psychological elder abuse (EA) and promote high-quality caregiving by lowering relationship strain and…
- Conditions
- Elder Mistreatment, Elder Abuse, Quality of Care, Dementia
- Trial name
- KINDER (NCT07216950)
- Testing
- Knowledge and Interpersonal Skills to Develop Enhanced Relationships, Healthy Living for the Caregiver
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
HIV Infections
Midwest TXTXT Scale up of an Evidence-Based Intervention to Promote HIV Medication Adherence
This research study uses a cluster randomized controlled trial design to evaluate the effectiveness of Treatment Text (TXTXT) intervention on adherence and viral load suppression at 3- and 6- months post intervention initiation…
- Trial name
- NCT05783297
- Testing
- Treatment Text (TXTXT), Standard of Care
- Where
- 12 sites in United States
- Volunteers
- 210 people
- Sponsor
- Amy K. Johnson, PhD, MSW
Human Papillomavirus Viruses, Papillomavirus Vaccines
Let's K-Talk - HPV Study for Ethnic Koreans
The goal of this clinical trial is to test the feasibility, acceptability, and preliminary efficacy of a storytelling video-based intervention using AI chatbot technology (K-Talk) to promote HPV vaccination behavior among Korean…
- Trial name
- NCT05884697
- Testing
- K-Talk Intervention (Storytelling and K-Bot), Storytelling Intervention, K-Bot Intervention
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Opioid-Related Disorders, Drug Overdose
Repeated-dose Behavioral Intervention to Reduce Opioid Overdose
REBOOT is a randomized trial of a repeated-dose brief intervention to reduce overdose and risk behaviors among naloxone recipients with opioid use disorder.
- Trial name
- REBOOT (NCT03838510)
- Testing
- REBOOT
- Where
- 2 sites in United States
- Volunteers
- 268 people
- Sponsor
- San Francisco Department of Public Health
Acute Myocardial Infarction (AMI)
Stellate Ganglion Morphine Infiltration on Myocardial I/R Injury
The goal of this clinical trial is to investigate whether morphine modulates the functions of the stellate ganglion to reduce myocardial ischemia/reperfusion (I/R) injury in AMI patients.
- Trial name
- tSGM-AMI (NCT07023679)
- Testing
- Morphine
- Where
- 2 sites in China
- Volunteers
- 2,588 people
- Sponsor
- The Second Hospital of Anhui Medical University
Depression
Cognitive Bias Modification (CBM) and Internet Cognitive Behavioural Therapy (iCBT) for Depression- A Randomised Controlled Trial
Cognitive accounts of depression and anxiety emphasize the importance of cognitive biases in the maintenance of disorders. One specific bias is the interpretation of ambiguous information.
- Trial name
- NCT01488058
- Testing
- OxIGen + iCBT, Waitlist Control
- Where
- Australia
- Volunteers
- 69 people
- Sponsor
- Alishia Williams
Gastro-esophageal Cancer
PeRioperative Study of Exercise Training in Patients With Operable Cancer of the Gastroesophageal Junction
Background: For patients diagnosed with operable cancer of the gastro-esophageal junction (GEJ), the perioperative course of therapy is associated with severe deconditioning which includes weight loss and poor physical function…
- Trial name
- PRESET (NCT02722785)
- Testing
- Aerobic and Resistance Exercise Training
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Jesper Frank Christensen, PhD
Prostate Cancer
Local Anesthesia for Prostate Biopsy
Title: Local anesthesia for office biopsy of the prostate: effects on pain control, quality of life and surgical intervention. Introduction: Local anesthetic should be administered prior to transrectal needle biopsy of the…
- Trial name
- NCT00422708
- Testing
- Local anesthesia
- Where
- United States
- Volunteers
- 243 people
- Sponsor
- Mayo Clinic
Osteo Arthritis Knee
The Effect of Smart Ring Assisted Physiotherapeutic Intervention After TKR
The goal of this randomized controlled trial is to learn about the effect of a wearable activity tracker assisted physiotherapeutic intervention on the risk of poor patient reported outcome after a primary total knee replacement.
- Trial name
- SmarTKRing (NCT05599776)
- Testing
- Smart ring assisted physiotherapeutic intervention
- Where
- Finland
- Volunteers
- 338 people
- Sponsor
- Coxa, Hospital for Joint Replacement
Human Papillomavirus-Related Carcinoma
A Vaccine Promotion Package (TweenVax) to Improve Adolescent HPV Vaccination, TweenVax Trial
This clinical trial compares the effect of a vaccine promotional intervention, TweenVax, to standard of care vaccination promotion practices on rates of human papillomavirus (HPV) vaccination in adolescents.
- Trial name
- NCT07104240
- Testing
- Best Practice, Educational Intervention, Health Promotion and Education
- Where
- United States
- Volunteers
- 1,836 people, healthy volunteers welcome
- Sponsor
- Emory University
Teen Pregnancy, Contraception Behavior
Evaluation of an Adolescent Pregnancy Prevention Program; Relationship Smarts+ With Lessons From Mind Matters
The goal of this randomized control trial (RCT) is to assess an innovative adolescent pregnancy prevention program among youth that are at the highest risk of adolescent pregnancy, to prevent pregnancy and Sexually Transmitted…
- Conditions
- Teen Pregnancy, Contraception Behavior, Sexually Transmitted Diseases, Reproductive Health
- Trial name
- NCT05889689
- Testing
- Relationship Smarts Plus & Mind Matters, Relationship Smarts Plus alone, Preparing Adolescents for Young Adulthood (PAYA).
- Where
- United States
- Volunteers
- 945 people, healthy volunteers welcome
- Sponsor
- Trinity Church Inc.
Suicide, Attempted
Study About Treatment After a Suicide Attempt
Effective, brief, low-cost interventions for individuals who attempt suicide are needed to save lives and achieve the goals of the National Strategy for Suicide Prevention.
- Trial name
- NCT03894462
- Testing
- Attempted Suicide Short Intervention Program, Zero Suicide Usual Care
- Where
- 3 sites in United States
- Volunteers
- 443 people
- Sponsor
- University of Rochester
Aortic Valve Stenosis, Intracranial Embolism and Thrombosis
NAUTILUS CE-mark Trial of the FLOWer Cerebral Embolic Protection Device
The purpose of this clinical study is to assess the safety, performance, and treatment effect of the use of the AorticLab FLOWer System, in preventing cerebral thromboembolic complications in patients with indication for a TAVI…
- Trial name
- NAUTILUS (NCT04704258)
- Testing
- TAVI (Transcatheter Aortic Valve Implant), FLOWer Embolic Protection System
- Where
- 8 sites in Belgium, Italy
- Volunteers
- 100 people
- Sponsor
- AorticLab Srl
Contrast Media Reaction, Acute Renal Failure
IVUS Guidance to Reduce Contrast in Coronary Angioplasty
This study tests the hypothesis that ultrasound-guided PCI reduces contrast volume during the procedure.
- Trial name
- MOZART (NCT01947335)
- Testing
- IVUS-guided PCI
- Where
- Brazil
- Volunteers
- 83 people
- Sponsor
- InCor Heart Institute
Lung Disease
Comparing Methods for Tracking Health Information at Home After Lung Transplant
The purpose of this randomized controlled trial is to test the efficacy of a novel intervention, Pocket PATH (Personal Assistant for Tracking Health) for promoting self-care agency, self-care behaviors, and transplant-related…
- Trial name
- NCT00818025
- Testing
- Pocket PATH (Personal Assistant for Tracking Health)
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- University of Pittsburgh
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