Clinical trials: Interventions
Postpartum Depression, Postpartum Anxiety
Improving Maternal Sleep and Mental Health
The goal of this clinical trial is to test the effectiveness of a Smart Bassinet to prevent/mitigate postpartum mood disorders by augmenting maternal sleep and/or enhancing infant sleep.
- Conditions
- Postpartum Depression, Postpartum Anxiety, Sleep Disturbance, Infant Behavior
- Trial name
- SHINE (NCT06544941)
- Testing
- Smart Bassinet, HALO
- Where
- United States
- Volunteers
- 342 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Colorado Springs
Pediatric Cancer, Adolescent and Young Adult Cancer
Improving Communication Between AYA Oncology Patients and Clinicians: A Patient-Centered Intervention
The overarching goal is to develop and demonstrate proof-of-concept of ReSPECT (Reproductive and Sexual Health Patient Education and Communication Tool), a multi-modal communication intervention to improve adolescent and young…
- Trial name
- NCT06982066
- Testing
- ReSPECT
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Connecticut Children's Medical Center
Intestinal Bacteria Growth
The Impact of Dietary Flavanols on the Gut Microflora
The primary propose of this study is to determine the impact of flavanol-rich cocoa on the growth of the human gut microbiota.
- Trial name
- NCT01091922
- Testing
- Low flavanol cocoa beverage, High flavanol cocoa beverage
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Reading
Coronary Artery Disease, Ischemic Heart Disease
Coronary and Structural Interventions Ulm - Bioresorbable Vascular Scaffold
To evaluate the safety, performance and efficacy of the bioresorbable vascular scaffold (BVS) system in patients with coronary artery disease
- Conditions
- Coronary Artery Disease, Ischemic Heart Disease, Stable Angina, Unstable Angina
- Trial name
- CSI-Ulm-BVS (NCT02162056)
- Testing
- use of bioresorbable vascular scaffolds
- Where
- Germany
- Volunteers
- 326 people
- Sponsor
- University of Ulm
Nutrition, Physical Activity
A Web-based Tailored Health Behavior Intervention for Breast and Colon Cancer Survivors (eWellness)
The primary objective of this study is to compare the differences in fruits and vegetable intake and physical activity from pre- to post- study between the intervention and control groups (i.e. the difference in differences).
- Trial name
- eWellness (NCT04188002)
- Testing
- Intervention Physical Activity, Usual Care
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of North Carolina, Chapel Hill
Anxiety Disorders, Depressive Disorder
Effectiveness and Underlying Mechanisms of Applied Relaxation as Indicated Preventive Intervention
As mental disorders constitute a core health care challenge of the 21th century, increased research efforts on preventive interventions are indispensable.
- Conditions
- Anxiety Disorders, Depressive Disorder, Stress Disorder
- Trial name
- EASY (NCT03311529)
- Testing
- Applied Relaxation
- Where
- Germany
- Volunteers
- 277 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Insulin-dependent Gestational Diabetes
PINGUIN (Postpartum Intervention in Women With Gestational Diabetes Using Insulin)
The aim of the study is to prove the efficacy of the oral intake of vildagliptin in a daily dose of 100 mg in scope of the development of type 2 diabetes in women with insulin dependent gestational diabetes in their last…
- Trial name
- NCT01018602
- Testing
- vildagliptin, inactive pill
- Where
- Germany
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Institut fur Diabetesforschung, Munich, Germany
Acute Myocardial Infarction, Percutaneous Coronary Intervention
CardiOvascular Risk and idEntificAtion of Potential High-risk Population in Acute Myocardial Infarction II (COREA-AMI II)
This study is intended to provide contemporary data on the residual cardiovascular risk in all consecutive patients with acute myocardial infarction, especially in patients who survived stably within one-year after percutaneous…
- Conditions
- Acute Myocardial Infarction, Percutaneous Coronary Intervention, Major Adverse Cardiovascular Events, Bleeding
- Trial name
- NCT02806102
- Testing
- Percutaneous coronary intervention, Dual-antiplatelet therapy
- Where
- 2 sites in South Korea
- Volunteers
- 13,000 people
- Sponsor
- Seoul St. Mary's Hospital
Older Adults, Healthy Aging
danceSing Care Evaluation: Testing the Effectiveness
This pilot randomised controlled trial aims to compare the effectiveness of a 12-week music and movement intervention in older adults in care homes compared to a waitlist control group.
- Conditions
- Older Adults, Healthy Aging, Aging, Quality of Life
- Trial name
- NCT05601102
- Testing
- danceSing Care
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Stirling
Asthma in Children
A Culturally Tailored Scalable Asthma Intervention for Hispanic Children (Asthma Guardian)
This is a two-arm, parallel design, randomized, controlled pilot trial comparing access to Asma Guardián, a culturally tailored multi-component app-based asthma intervention for Hispanic/Latinx school age children with asthma, to…
- Trial name
- NCT05892302
- Testing
- Access to Asma Guardian website/app, Delayed Access to Asma Guardian website/app
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Texas at Austin
Hypertension
Community Based Health Education to Manage Uncontrolled Blood Pressure in Surkhet, Nepal
The purpose of the study is to evaluate the effect of health education on blood pressure reduction compared to usual care among uncontrolled hypertensive patients of suburban community of Surkhet district of Nepal.
- Trial name
- NCT02981251
- Testing
- Health education with support by trained female health volunteer
- Where
- Nepal
- Volunteers
- 142 people
- Sponsor
- Bheri Zonal Ayurveda Hospital
Obesity
Obesity Intervention Program for University Students
The aim of this study is to determine the effect of preventive nursing interventions, which consist of education / practices including of healthy eating and physical activity and motivational messages which sent through social…
- Trial name
- NCT03115229
- Testing
- Protective Nursing Interventions for Reduction Obesity Risk
- Volunteers
- 70 people
- Sponsor
- Selcuk University
Stroke
High Intensity Interval Training for People With Stroke Deficits
The purpose of this study is to compare the effects of an exercise training strategy called high-intensity interval training (HIIT) to moderate intensity continuous exercise (MICE), on walking function and cardiovascular fitness…
- Trial name
- HIIT-Stroke (NCT03006731)
- Testing
- High Intensity Interval Training, Moderate Intensity Continuous Exercise
- Where
- Canada
- Volunteers
- 47 people
- Sponsor
- University Health Network, Toronto
Malnutrition in Children
Developmental Screening and Nutritional Intervention of Severe Acute Malnourished Children in Southern Punjab, Pakistan
i. To examine the impact of malnutrition on development quotient of children ii. To determine the effectiveness of Ready to Use Therapeutic Food (RUTF) in improving the development quotient of severe acute malnourished children…
- Trial name
- NCT03170479
- Testing
- Vitamin D, Ready to Use Therapeutic Food (RUTF)
- Volunteers
- 185 people
- Sponsor
- University of the Punjab
Depression, Major Depressive Disorder
The Efficacy of Automated Feedback After Internet-based Depression Screening
The DISCOVER randomized controlled trial is designed to evaluate the effect of automated feedback after internet-based depression screening in individuals with undetected depression.
- Trial name
- DISCOVER (NCT04633096)
- Testing
- tailored feedback of depression screening results, standardized feedback of depression screening results
- Where
- Germany
- Volunteers
- 1,178 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
HIV/AIDS, Sexually Transmitted Diseases
A Pilot Peer Mentor Intervention That Trains Black Men Who Have Sex With Men (BMSM) to Use and Promote Uptake of HIV/STI Self-Testing to Peers and Sex Partners: STAR Study (Self-Testing at Your Residence)
The objectives of the study are to assess the feasibility, reach and preliminary efficacy of a brief intervention that trains Black men who have sex with men [referred to as Index] (a) to use home-based testing for HIV and…
- Trial name
- STAR (NCT04121962)
- Testing
- Peer Mentor, Website only
- Where
- United States
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Physical Inactivity
Understanding Motivation Towards Exercise to Enhance Physical Activity on Prescription Adherence - Feasibility Study
The goal of this clinical trial is to explore feasibility and evaluate methods to investigate changes in physical activity, function and psychometrics in relation to an exercise intervention in physically inactive middle-aged men…
- Trial name
- UMEPA-F (NCT05691803)
- Testing
- Exercise intervention
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Umeå University
Sedentary Lifestyle
Mobile-based Online Social Network Intervention to Increase Physical Activity
Despite the racial disparities in rates of chronic diseases and behaviors linked to chronic diseases, there have been relatively few RCTs of interventions to increase physical activity in African American women.
- Trial name
- PennFit (NCT02736903)
- Testing
- PennFit mobile individual intervention, PennFit mobile online network intervention
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Critical Illness
Multi-component Family Support Tool Intervention (FST)
The National Academy of Medicine and the National Institutes of Health have called for urgent action to improve the care delivered to the nearly 1,000,000 older Americans who die in intensive care units (ICUs) annually or survive…
- Trial name
- FST (NCT05019261)
- Testing
- Multi-component Family Support Intervention
- Where
- 7 sites in United States
- Volunteers
- 1,039 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Adolescent Drinking, Adolescent Substance Use
Optimizing and Advancing SBIRT in Schools
The goal of this clinical trial is to establish whether brief interventions for alcohol use can be delivered in schools for both indicated prevention and selected prevention, determine if an expanded workforce is an effective…
- Conditions
- Adolescent Drinking, Adolescent Substance Use, Risk Behavior, Health
- Trial name
- OASIS (NCT06206161)
- Testing
- Indicated Prevention, Clinical Staff, Selective Prevention, Expanded Paraprofessional Workforce
- Where
- United States
- Volunteers
- 21,000 people
- Sponsor
- Massachusetts General Hospital
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