Clinical trials: Interventions
Schizophrenia
Coaching Intervention for Patients With Early Psychosis
Jockey Club Early Psychosis (JCEP) project is a territory-wide specialized EI service that is launched in August 2009 and provides 3-year phase-specific intervention for adult patients presenting with first-episode psychosis…
- Trial name
- NCT01792856
- Testing
- Recovery-oriented intervention, psychoeducation
- Where
- China
- Volunteers
- 140 people
- Sponsor
- The University of Hong Kong
To Assess the Impact of the HIT Intervention on Physiological Responses, To Assess the Role of a Secondary High School as a Setting for Promoting Healthy Eating and PA Behaviours
The Influence of a High Intensity Physical Activity Intervention on a Selection of Health Related Outcomes: An Ecological Approach
The purpose of this study is to determine whether a High Intensity exercise intervention can elicit cardiovascular disease protection in adolescents.
- Conditions
- To Assess the Impact of the HIT Intervention on Physiological Responses, To Assess the Role of a Secondary High School as a Setting for Promoting Healthy Eating and PA Behaviours, To Determine the Associations Between CVD Risk Factors at Baseline in 15 - 18 Year Old Youth
- Trial name
- NCT01027156
- Testing
- High Intensity Exercise
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of the West of Scotland
Acute Ischemic Stroke
Feasibility Study of RapidPulseTM Aspiration System as Frontline Approach for Patients With Acute Ischemic Stroke
A feasibility study to evaluate the initial safety and performance of the RapidPulseTM Aspiration System in the treatment of patients with Acute Ischemic Stroke (AIS) due to Large Vessel Occlusion (LVO) in the intracranial ICA…
- Trial name
- PULSE-F (NCT05577351)
- Testing
- RapidPulseTM Aspiration System
- Where
- 2 sites in Georgia
- Volunteers
- 5 people
- Sponsor
- RapidPulse, Inc
Safety of Intervention, Efficacy of Intervention
Video-assisted Hyperthermic Pleural Chemoperfusion vs Talc Pleurodesis for Refractory Malignant Pleural Effusions.
Aim of this study is to compare two methods of pleurodesis for refractory malignant pleural effusions, in terms of safety and efficacy.
- Conditions
- Safety of Intervention, Efficacy of Intervention, Cost Effectiveness
- Trial name
- NCT01409551
- Testing
- VATS hyperthermic chemoperfusion, Bedside talc slurry pleurodesis
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Theagenio Cancer Hospital
Parents
Effectiveness of a Web-based Intervention on Parental Psychological Flexibility and Emotion Regulation
This project aims to validate a web-based clinical intervention for families with children suffering neurodevelopmental or behavioral disorders to promote psychological flexibility and emotion regulation strategies in parents.
- Trial name
- NCT04267523
- Testing
- Web parenting intervention, Group parenting intervention
- Where
- 2 sites in Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universidad de Almeria
HIV (Human Immunodeficiency Virus)
Boosting Olfactory and Sensory Training Study (BOOST)
The goal of this study is to examine two types of olfactory interventions (conventional olfactory training vs scented marker training) in adults with HIV. The two research questions are: 1.
- Trial name
- BOOST (NCT07221123)
- Testing
- Conventional Smell Training Group, Scented Marker Group
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Alabama at Birmingham
Adherence, Pregnancy
Evaluation of an Intervention for Optimizing Pregnant Women's Adherence to Maternal Multiple Micronutrients Supplements
In collaboration with the Federal Government of Nigeria and Bauchi State, Nutrition International (NI) conducted a three-year implementation research study to assess whether adherence solutions - developed through a…
- Trial name
- NCT07644780
- Testing
- Implementation Approaches
- Where
- 3 sites in Nigeria
- Volunteers
- 2,601 people, healthy volunteers welcome
- Sponsor
- Nutrition International
Parents, Self Efficacy
Text-messaging Intervention to Support Parents After Their Child's Psychiatric Emergency
This grant aims to develop and test a text-messaging intervention for parents of children and teens evaluated in the emergency department for a psychiatric emergency and discharged home with outpatient referrals.
- Conditions
- Parents, Self Efficacy, Mental Health Literacy, Psychiatric Emergency
- Trial name
- iPEACE (NCT06456762)
- Testing
- iPEACE: Intervention for Parent Education about Care after the ED, Text Messaging Reminders Only
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Vanderbilt University Medical Center
Obesity, Weight Loss
Protein Supplementation Intervention on Body Weight
This study is a randomized clinical trail with a parallel design, involving 120 overweight/obese (body-mass index, BMI ≥ 24 kg/m²) participants and 20 normal-weight participants.
- Conditions
- Obesity, Weight Loss, Protein Supplementation
- Trial name
- NCT06989203
- Testing
- General lifestyle and nutritional education, Calorie-restricted balanced diet, semaglutide
- Where
- China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Sciences
Coronary Artery Disease
OPTIMIZE PCI: Multicenter Randomized Trial of OCT Compared to IVUS and Angiography to Guide Coronary Stent Implantation
The objective of this clinical investigation is to demonstrate the safety and efficacy of an OCT guided strategy for stent implantation
- Trial name
- ILUMIEN III (NCT02471586)
- Testing
- Coronary PCI guided by IVUS, Coronary PCI guided by OCT, Coronary PCI guided by Angiography
- Where
- 29 sites in United States, Belgium and 6 more
- Volunteers
- 450 people
- Sponsor
- Abbott Medical Devices
Anxiety, Depressive Symptoms
Online or In-person Interventions on Anxiety and Depression Symptoms in Caregivers of Patients with Cancer
Oncological diseases are considered a family disease because when one member is diagnosed with cancer, the psycho-physical, social and economic consequences affect the entire family.
- Trial name
- CBT_ONLINE (NCT06592573)
- Testing
- CBT_ONLINE, CBT_IN PERSON
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Fondazione ANT Franco Pannuti ETS
Breast Cancer, Gynecologic Cancer
Mindful After Cancer: A Mindfulness-based Therapy Intervention for Sexual Health After Cancer
The objectives of this study are to: 1) adapt a mindfulness-based therapy program designed to help women manage their sexual and body image concerns after cancer (Mindful After Cancer, MAC) to a videoconference format and 2)…
- Trial name
- MAC (NCT04559854)
- Testing
- Mindful After Cancer
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Oregon State University
Coronary Artery Disease
Everolimus- Versus Biolimus-Eluting Stents in All-Comers
This study sought to investigate safety and efficacy of biolimus-eluting stents (BES) with biodegradable polymer as compared with everolimus-eluting stents (EES) with durable polymer through 3 years of follow-up.
- Trial name
- EverBio (NCT01472705)
- Where
- Switzerland
- Volunteers
- 814 people
- Sponsor
- University of Freiburg
Smoking Cessation, Psychiatric Illness
Reducing Cardiovascular Disease by Combining Smoking Cessation Pharmacotherapy and Behavioural Counseling
Research Aims The aims of this research study are: 1. To determine which of the following three smoking cessation medications is most effective in achieving cessation: Nicotine Patch Nicotine Patch + gum or inhaler Varenicline…
- Trial name
- RW (NCT01623505)
- Testing
- Champix, Transdermal Nicoderm patch combined with gum or inhaler, Transdermal Nicoderm patch
- Where
- Canada
- Volunteers
- 738 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Cardiovascular Diseases, Sickle Cell Disease
SCD Fit Homebase Program
The purpose of this project is to develop novel approaches to promote health and longevity while enhancing quality of life among persons with Sickle cell disease (SCD).
- Conditions
- Cardiovascular Diseases, Sickle Cell Disease, Exercise
- Trial name
- NCT05228756
- Testing
- Accelerometer
- Sponsor
- University of Alabama at Birmingham
Healthy Men Age 50 Who Are Considering PSA Screening
Decision Support Interventions (DESI) for Prostate Cancer Screening - Study 1
In this study we will compare 3 strategies for systematic delivery of prostate cancer screening decision support interventions (DESI) to usual care and examine their impact on screening decisions and subsequent healthcare…
- Trial name
- NCT01241656
- Testing
- DESI for home viewing, DESI for viewing at Shared Medical Appointment, Option of SMA and DESI or DESI only
- Where
- 2 sites in United States
- Volunteers
- 2,521 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Borderline Personality Disorder
Cognitive Reappraisal Training for Borderline Personality
Previous work by the study group convinced the study team to pursue development of focused cognitive reappraisal training as a novel approach to treatment of BPD, either as stand-alone treatment or in concert with evidence-based…
- Trial name
- BPD (NCT04967222)
- Testing
- Cognitive Reappraisal by Distancing, Control Downregulate Condition
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hepatitis B, Hepatitis C
Patient-Centered Care and Asian Americans
Liver cancer and hepatitis B are health disparities for Asian Americans, and hepatitis C is a rising problem. Little is known about how to improve the quality of health care Asian Americans receive for viral hepatitis.
- Conditions
- Hepatitis B, Hepatitis C, Liver Disease
- Trial name
- NCT02139722
- Testing
- Video Doctor, PA + PPN
- Where
- 2 sites in United States
- Volunteers
- 431 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Anemia, Sickle Cell
Specifying Interventions From the Sickle Cell Disease Implementation Consortium (SCDIC)
The goal of this study is to specify the interventions, implementation strategies and control conditions from the Sickle Cell Disease Implementation Consortium (SCDIC) using a mixed-methods approach to study site materials and…
- Trial name
- NCT03380351
- Testing
- SCDIC interventions
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Chronic Low-back Pain, Patient Activation
Self-Management of Chronic Low Back Pain: Targeting Patient Activation
Patients with chronic low back (cLBP) pain report reduced physical function and ability to participate in social roles and are more likely to use opioid pain medications.
- Trial name
- NCT06236529
- Testing
- Health Behavior Change Counseling, Self-management program
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Johns Hopkins University
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