Clinical trials: Interventions
Type 1 Diabetes
PREVENTKD (Prevent Risks by Early interVEntion at Nighttime in Type 1 Diabetes for Kidney Disease)
The purpose of this study is to determine if the early treatment with a blood pressure medication (an ACE Inhibitor) can prevent or delay the development of kidney disease (microalbuminuria) in patients with Type 1 diabetes who…
- Trial name
- PREVENTKD (NCT00729365)
- Testing
- Ramipril
- Where
- 6 sites in United States
- Volunteers
- 65 people
- Sponsor
- Northwestern University
Smoking Cessation, HIV
Patch Study - Intervention for HIV Positive Smokers
The overall objective of the transdisciplinary team of Human Immunology Virus (HIV) and Tobacco funded researchers is to test if tailoring nicotine replacement doses to temper these excessive levels will enhance the efficacy of…
- Trial name
- NCT02982772
- Testing
- Combination Therapy, Standard Care Intervention
- Where
- United States
- Volunteers
- 488 people
- Sponsor
- dr. maria miguez
Smoking Cessation
Use of Nicotine Replacement Therapy (NRT) Sample and Brief Smoking Cessation Advice for Recruiting Smokers
Background More than 60% of the daily smokers in Hong Kong have never tried and have no intention to quit smoking. About 30.8% of daily smokers attempted to quit but failed.
- Trial name
- NCT03717051
- Testing
- Nicotine replacement therapy (NRT) sampling, Medication counseling
- Where
- Hong Kong
- Volunteers
- 834 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
HIV Infections, Sexually Transmitted Diseases
Evaluation of Many Men, Many Voices, An STD/HIV Prevention Intervention for Black MSM
The purpose of this program evaluation is to determine whether the "Many Men, Many Voices" HIV/STD prevention intervention is effective in reducing HIV sex risk behaviors and increasing HIV testing among African-American men who…
- Trial name
- 3MV (NCT00137631)
- Testing
- Many Men, Many Voices (3MV)
- Where
- United States
- Volunteers
- 341 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Sarcoma
A Public Health Intervention Program to Improve the Initial Management of Soft Tissue Sarcomas.
Sarcomas are rare tumours that represent less than 1% of cancers. Their actual incidence in France, however, is not known. The chances of survival at 5 years, without signs of the disease, are currently estimated at about 60%.
- Trial name
- IPSSAR (NCT05007639)
- Testing
- Public Health intervention programme, No public Health intervention programme
- Volunteers
- 274 people
- Sponsor
- Institut Bergonié
Colon Cancer, Lung Cancer
Effectiveness of Electronic Health Record-Based Interventions for Improving Follow-Up in Primary Care
Diagnostic delays in ambulatory care are often due to breakdowns of related care processes. Electronic systems can improve follow-up and reduce delays by detecting missed appointments or incomplete procedures so that patients are…
- Conditions
- Colon Cancer, Lung Cancer, Prostate Cancer
- Trial name
- NCT01346839
- Testing
- Contact Intervention
- Where
- 2 sites in United States
- Volunteers
- 1,256 people
- Sponsor
- Baylor College of Medicine
Suicide
CAMS-RAS: for Suicide Prevention
This Phase I feasibility study endeavors to create a prototype of a tool to determine its feasibility with suicidal patients in emergency departments (EDs). This is not a clinical trial.
- Trial name
- CAMS-RAS (NCT03072875)
- Testing
- CAMS-RAS
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Evidence-Based Practice Institute, Seattle, WA
Hiv
Adapting the Finding Respect and Ending Stigma Around HIV (FRESH) Intervention for the Dominican Republic
This research has the potential to make important contributions toward HIV and intersectional stigma reduction across the Spanish-speaking Caribbean.
- Trial name
- NCT04491539
- Testing
- Finding Respect and Ending Stigma around HIV (FRESH)
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Florida State University
Type 1 Diabetes Mellitus
Check It! Positive Psychology Intervention to Improve Adherence in Adolescents With T1D
Problems with diabetes management in adolescents with type 1 diabetes are common - occurring at rates as high as 93% - and have serious health consequences, including poor blood sugar control and risk for later complications.
- Trial name
- NCT02746627
- Testing
- Positive Affect, Education
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Vanderbilt University Medical Center
Lower Back Pain
Investigating the Effects of a Spinal Mobilisation Intervention in People With Lower Back Pain
The objective of the study is to measure and analyse the effect of a spinal mobilisation intervention on muscle tissue quality in people with lower back pain.
- Trial name
- NCT04012970
- Testing
- Manual spinal mobilisations
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Edinburgh Napier University
Alcohol Dependence, Alcohol Use Disorder
Extended-release Naltrexone and Care Management for Alcohol Dependent Frequent Emergency Department Users
Our primary aim is to assess the feasibility of initiating treatment in the ED with extended-release naltrexone (XR-NTX) plus care management (CM) vs.
- Trial name
- NCT02445339
- Testing
- XR-NTX+CM (Extended-Release Naltrexone plus Care Management)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NYU Langone Health
Self Efficacy, Loneliness
Putting Life in Years (PLINY): Telephone Friendship Groups Research Study
The National Institute for Health Research commissioned this research with the following research question: "What is the relative effectiveness and cost effectiveness of home based support programmes in improving the mental…
- Trial name
- PLINY (NCT01754753)
- Testing
- Telephone Friendship groups
- Where
- United Kingdom
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
Breast Cancer, Insomnia
Brief Behavioral Intervention for Insomnia During Chemotherapy
PRIMARY OBJECTIVE(S): To evaluate the efficacy of the Brief Behavioral Therapy for Insomnia (BBT-I) in treating insomnia among breast cancer patients receiving chemotherapy.
- Trial name
- NCT02165839
- Testing
- Brief Behavioral Therapy for Insomnia (BBT-I), Healthy Eating Education Learning (HEAL)
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Stanford University
Children, Overweight
The Odense Overweight Intervention Study
Strong and consistent evidence have shown that overweight, including obesity, is an important risk factor for the development of cardiovascular disease (CVD) in adults.
- Conditions
- Children, Overweight, Obesity, Metabolic Syndrome
- Trial name
- OOIS (NCT01574352)
- Testing
- Small intervention, Intervention camp
- Where
- 2 sites in Denmark
- Volunteers
- 115 people
- Sponsor
- University of Southern Denmark
Substance Abuse
Preventing Drug Abuse Among Sexual Minority Youth
The planned randomized clinical trial will longitudinally test a tailored, web-based drug abuse prevention program with a nationwide sample of 15- to 17-year-old sexual minority youth (youth who identify as gay, lesbian…
- Trial name
- NCT03954535
- Testing
- Free2b
- Where
- United States
- Volunteers
- 1,216 people, healthy volunteers welcome
- Sponsor
- Columbia University
Cardiovascular Disorder, Coronary Artery Disease
A Sugar-Sweetened Beverage Reduction Intervention for Native American Men
This clinical trial develops and tests a culturally-appropriate educational program (Indigenous SIPin) for reducing sugar-sweetened beverage consumption in men affiliated with Native American athletics communities.
- Conditions
- Cardiovascular Disorder, Coronary Artery Disease, Diabetes Mellitus, Obesity-Related Malignant Neoplasm
- Trial name
- NCT06029517
- Testing
- Education Intervention, Observation of Indigenous SIPin Interventon, Discussion
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Burnout, Stress
Inner Engineering Online (IEO) Intervention for a Specific Company Employee Program
In this randomized controlled trial; differences in overall stress, burnout and wellbeing will be assessed for employees of a company participating in Inner Engineering Online, an online mind-body course that incorporates both…
- Conditions
- Burnout, Stress, Depression, Anxiety
- Trial name
- NCT04126564
- Testing
- Inner Engineering Online, Reading a book/ journal
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Diabetes Mellitus, Type 2
Dulce Digital-Me: An Adaptive mHealth Intervention for Underserved Hispanics With Diabetes
This study will compare Dulce Digital (i.e., the investigators' proven-effective combination of "one-size-fits-all" educational text messages and nurse monitoring of patient-transmitted blood glucose values) and Dulce Digital-Me…
- Trial name
- DD-Me (NCT03130699)
- Testing
- Dulce Digital, Dulce Digital-Me (Automated Delivery), Dulce Digital-Me (Medical Assistant)
- Where
- 2 sites in United States
- Volunteers
- 310 people
- Sponsor
- Scripps Whittier Diabetes Institute
Early Child Development
Testing Means to Scale Early Childhood Development Interventions in Rural Kenya
This study aims to experimentally test the effectiveness and cost-effectiveness of competing models of delivery of an Early Childhood Development (ECD) intervention in rural Kenya to determine how to maximize their reach to…
- Trial name
- NCT03548558
- Testing
- Group sessions, Group+Home sessions, Booster sessions
- Where
- United States
- Volunteers
- 1,152 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Long-Term Memory Decline, Mild Cognitive Impairment
Wayfinding Intervention in High-Fidelity Long-Term Memory
Therapeutic treatment is yet available for declining memory, which is an impairment affecting the quality of life for many older adults and patients with cognitive impairment.
- Trial name
- LABYR (NCT04253587)
- Testing
- LabyrinthVR, Coherence, Tablet
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
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