Clinical trials: Interventions
Chronic Disease, Mental Health
Optimizing Behavioral Health Homes for Adults With Serious Mental Illness
Adults with serious mental illness (SMI) frequently have unmet medical needs which place them at risk for adverse health outcomes.
- Conditions
- Chronic Disease, Mental Health, Behavioral Health, Cardiovascular Disease
- Trial name
- PCORI OH (NCT02318797)
- Testing
- Patient Self-Directed Care, Provider-Supported Integrated Care
- Where
- United States
- Volunteers
- 1,229 people
- Sponsor
- University of Pittsburgh
Migraine
Treximet Early Intervention Adolescent Migraine
The study involves approximately 105 adolescent (ages 12-17) subjects to be screened at 4 sites across the US. All subjects enrolled will treat up to 4 MILD migraines over a 6 month period.
- Trial name
- TEAM (NCT01016678)
- Testing
- Treximet
- Where
- 4 sites in United States
- Volunteers
- 104 people
- Sponsor
- Premiere Research Institute
Stroke, Ischemia
Analysis of Revascularization in Ischemic Stroke With EmboTrap
The study objective is to examine the recanalization efficacy of the EmboTrap device and its associated performance characteristics and to record associated clinical outcomes in a manner that facilitates relevant comparison of…
- Trial name
- ARISEII (NCT02488915)
- Testing
- EmboTrap® Revascularization Device
- Where
- 12 sites in United States, Belgium and 2 more
- Volunteers
- 228 people
- Sponsor
- Neuravi Inc.
Knee Osteoarthritis
Using Pressure Detecting Insoles to Reduce Knee Loading
The purpose of this study is to determine whether use of a pressure-detecting shoe improve can enhance favorable loading conditions at the knee.
- Trial name
- NCT02955225
- Testing
- Active Moticon OpenGO insole, Passive shoe insole
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Rush University Medical Center
Cigarette Smoking-Related Carcinoma
Website Smoking Cessation Intervention for the Promotion of Smoking Cessation in Low-Income Veterans
This phase I trial studies how well a new electronic (e)-health smoking cessation program (called Vet Flexiquit) works in promoting smoking cessation in low-income veterans who may or may not be ready to quit smoking.
- Trial name
- NCT04502524
- Testing
- Smoking Cessation Intervention (New website), Smoking Cessation Intervention (Standard of care website), Health Education
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Cardiac Toxicity, Malignant Neoplasm
MRI in Detecting Heart Damage in Patients With Cancer Receiving Chemotherapy With Exercise Capacity Addendum
This trial studies how well magnetic resonance imaging (MRI) works in detecting heart damage in patients with cancer receiving chemotherapy.
- Conditions
- Cardiac Toxicity, Malignant Neoplasm, Breast Cancer
- Trial name
- NCT01719562
- Testing
- Magnetic resonance imaging, Physical Activity, Healthy Living
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Wake Forest University Health Sciences
Stable Angina Pectoris, Atherosclerosis
Effect of Molsidomine on the Endothelial (Internal Layer of Blood Vessels) Dysfunction in Patients With Angina Pectoris
Molsidomine used as an add-on treatment on standard care therapy should be superior to placebo used also as an add-on treatment on standard care therapy on improving the endothelial function (endothelium score measured by…
- Trial name
- MEDCOR (NCT01363661)
- Testing
- Coruno
- Where
- Belgium
- Volunteers
- 165 people
- Sponsor
- Therabel Pharma SA/NV
Lung Cancer
Lung Cancer Exercise Training Study
The purpose of the study is look at the effects of different types of exercise training with a stretching group and its effect on lung cancer patients.
- Trial name
- NCT01068210
- Testing
- Aerobic Training, Progressive Stretching, Resistance Training
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
HIV-1-infection
Group-Based Intervention to Improve Mental Health and Adherence Among Youth Living With HIV in Low Resource Settings
IMPAACT 2016 was a multi-site, two-arm, individually randomized, controlled study to evaluate whether an Indigenous Leader Outreach Model (ILOM) of trauma-informed cognitive behavioral therapy (TI-CBT) delivered by Indigenous…
- Trial name
- NCT04024488
- Testing
- Youth TI-CBT Intervention Arm, Youth Discussion Control Arm, Caregiver TI-CBT Intervention Arm
- Where
- 8 sites in Botswana, Malawi and 2 more
- Volunteers
- 484 people
- Sponsor
- International Maternal Pediatric Adolescent AIDS Clinical Trials Group
Smoking, Heavy Episodic Drinking
Smoking Tobacco and Drinking Study
This trial will test the efficacy of a 3-month intervention on Facebook targeting tobacco use and heavy episodic drinking against a 3-month Facebook intervention targeting tobacco use.
- Trial name
- STAND (NCT03163303)
- Testing
- Tobacco Status Project Intervention, Tobacco Status Project + Alcohol Intervention, nicotine patch
- Where
- United States
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Care Transitions, Dementia
CAPABLE Transitions: A Home Health-Based Intervention for the Hospital or Post-Acute Care Facility-to-Home Transition
This clinical study is designed to test the feasibility of a new intervention, CAPABLE Transitions. CAPABLE Transitions is based on the Community Aging in Place, Advancing Better Living for Elders (CAPABLE) intervention designed…
- Trial name
- NCT04460742
- Testing
- CAPABLE Transitions, Home Health Agency Care
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Rochester
Secondary School Entry and Completion, Child Marriage
Evaluation of an Intervention for Adolescent Girls in Karnataka
This cluster Randomised Control Trial is evaluating an intervention to support adolescent girls from marginalised communities in northern Karnataka State, South India to complete secondary school, thereby reducing their…
- Trial name
- Samata (NCT01996241)
- Testing
- Multi-level, structural and norms-based intervention
- Where
- India
- Volunteers
- 2,457 people
- Sponsor
- Karnataka Health Promotion Trust
Mild Cognitive Impairment, Insomnia
Multicomponent Behavioral Sleep Intervention for Insomnia in Older Adults With Mild Cognitive Impairment
Insomnia symptoms in older adults with mild cognitive impairment represent a significant public health burden in terms of impaired quality of life, risks from untreated insomnia, and risks from pharmaceutical insomnia treatment.
- Trial name
- MBSI-I (NCT04364191)
- Testing
- Multicomponent Behavioral Sleep Intervention for Insomnia, Active Control
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Diabetes Mellitus
Evaluation of a Patient Portal Intervention to Address Diabetes Care Gaps
The purpose of this study is to evaluate the usability of a novel patient portal intervention designed to: (a) notify patients when selected, clinically meaningful, evidence-based diabetes monitoring \& preventative care (e.g.…
- Trial name
- NCT04728620
- Testing
- Diabetes Care Gaps Patient Portal Intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Vanderbilt University Medical Center
Impaired Fasting Glucose, Impaired Glucose Tolerance
D Vitamin Intervention in VA
This study will supplement African American male (AAM) veterans at risk for diabetes and newly diagnosed T2DM with vitamin D (low or higher dose) and evaluate whether vitamin D helps to improve early markers of diabetes.
- Conditions
- Impaired Fasting Glucose, Impaired Glucose Tolerance, Vitamin D Insufficiency
- Trial name
- DIVA (NCT01375660)
- Testing
- 50K vitamin D2
- Where
- United States
- Volunteers
- 205 people
- Sponsor
- US Department of Veterans Affairs
Urinary Incontinence
Ancillary Study of the Lessening Incontinence With Low-impact Activity Study
The parent trial that supports this ancillary research is a randomized controlled trial to evaluate the efficacy of a group-based yoga intervention to decrease the frequency and impact of urinary incontinence in ambulatory…
- Trial name
- NCT04776720
- Testing
- Yoga Practice Program, Physical Conditioning Program
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Diabetes Mellitus, Type 1
Strengths-Based Behavioral mHealth App for Parents of Adolescents With Type 1 Diabetes-Pilot Study
Type 1 diabetes (T1D) management is particularly challenging during adolescence as responsibility for management begins to shift from parents to youth, and positive family teamwork is critical to achieving optimal diabetes…
- Trial name
- T1DoingWell (NCT02877680)
- Testing
- T1Doing Well
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Baylor College of Medicine
Depression, Suicidal Ideation
Engaging Black Youth in Depression and Suicide Prevention Treatment Within Urban Schools
Completing evidence-based treatments for depression has been shown to be particularly problematic for Black adolescents. If Black adolescents' depression treatment needs are to be met, the engagement challenges and the factors…
- Trial name
- NCT03940508
- Testing
- Making Connections Intervention, IPT-A
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- New York University
Family Caregivers
Randomized Controlled Trial to Test an Alzheimer's Family Caregiver Intervention in Vietnam
This is a cluster randomized controlled trial to determine the feasibility and preliminary effectiveness of culturally adapted psychosocial intervention for Alzheimer's family caregivers in Vietnam.
- Trial name
- NCT03587974
- Testing
- REACH-VIETNAM
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- University of California, Davis
Opioid Dependence
Comparing Interventions for Opioid Dependent Patients Presenting in Medical Emergency Departments
This study will compare the effects of brief strengths-based case management (SBCM) to the effects of screening, assessment and referral alone (SAR) in opioid-dependent patients.
- Trial name
- NCT02586896
- Testing
- Strengths-based Case Management (SBCM), Screening, Assessment, and Referral (SAR)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- NYU Langone Health
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.