Clinical trials: Interventions
STEMI - ST-segment Elevation Myocardial Infarction
Metabolic Characteristics of Plasma OxPLs in STEMI Patients.
The goal of this observational study is to investigate the structural composition and metabolic characteristics of OxPLs in ST-segment elevation myocardial infarction(STEMI) patients.
- Trial name
- NCT07382700
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Ningbo University
Pediatric ALL, Infant Development
PANDA Gym: Automated Assessment of Neurodevelopment in Infants at Risk for Motor Disability
Early childhood detection of motor delays or impairments provides the opportunity for early treatment which improves health outcomes.
- Conditions
- Pediatric ALL, Infant Development, Neurodevelopmental Disorders
- Trial name
- NCT04321200
- Testing
- PANDA Gym, Mobile App
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Depression
Comparison Study of Family Practice Interventions for Depression in Adults
To determine if treatment of significant depressive symptoms identified in individuals attending a family practice improves either psychiatric outcome, overall health care costs, or Quality of Life (QOL).
- Trial name
- NCT01975207
- Testing
- Treatment as usual, Internet Intervention, Depression Treatment Pathway
- Volunteers
- 1,489 people, healthy volunteers welcome
- Sponsor
- AHS Cancer Control Alberta
Learning Disability
Enhancing Self-Understanding and Social Integration of Middle School Students With Learning Disabilities
Research and intervention programs for students with learning disabilities (LD) typically address child and family characteristics without examining the school context and conditions that affect adjustment.
- Trial name
- NCT00246792
- Testing
- Group treatment
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Toronto
Lumbar Disc Herniation, Preoperative Anxiety
Comparison of Virtual Reality-Based and Routine Preoperative Education on Surgical Anxiety and Salivary Cortisol
This randomized controlled pilot study aims to compare the effects of virtual reality-based preoperative education and routine preoperative education on surgical anxiety in patients undergoing lumbar disc surgery.
- Trial name
- NCT07443111
- Testing
- Virtual Reality-Based Preoperative Education, Routine Preoperative Education
- Volunteers
- 56 people
- Sponsor
- Bezmialem Vakif University
Obesity, Metabolic Syndrome
Milk Types and Fish Oil in 9- to 12-Month-Old Infants
The objective of this intervention study is to examine the effect of whole cow's milk versus infant formula as primary milk sources with or without supplements of n-3 LCPUFA for growth, nutritional status, development, risk…
- Conditions
- Obesity, Metabolic Syndrome, Growth, Blood Pressure
- Trial name
- NCT00379171
- Testing
- Cow's milk with fish oil, Cow's milk without fish oil, Formula with fish oil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Body Scan Meditation, Loving-Kindness Meditation
A Large Multi-site Study on Self-administered Mindfulness
The use of self-administered mindfulness interventions has increased in recent years. The effectiveness of these interventions on regulating stress/emotions, however, is debated.
- Conditions
- Body Scan Meditation, Loving-Kindness Meditation, Mindful Breathing Meditation, Mindful Walking Meditation
- Trial name
- NCT06308744
- Testing
- Body-scan meditation, Mindful Breathing meditation, Loving Kindness meditation
- Where
- United Kingdom
- Volunteers
- 2,239 people, healthy volunteers welcome
- Sponsor
- Swansea University
Menopause
Mindfulness-based Educational Intervention on Anxiety, Depression, Stress and Quality of Life on Menopausal Woman
Mindfulness-based educational intervention is a structured program that incorporates principles of mindfulness to help individuals develop greater awareness and acceptance of their thoughts, feelings, and bodily sensations.
- Trial name
- mindmenopaus (NCT06421909)
- Testing
- mindfulness-based educational intervention
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Masked Hypertension
Mechanism of Masked Hypertension - Intervention
To test the hypothesis that sympatholytic antihypertensive antihypertensive therapy (αβ-blocker - carvedilol) will reduce out-of-clinic ambulatory BP to a greater extent by blocking sympathetic activity than non-sympatholytic…
- Trial name
- NCT04121299
- Testing
- Carvedilol, Amlodipine
- Where
- United States
- Sponsor
- University of Alabama at Birmingham
First Episode Psychosis (FEP)
Digital Heart Rate Variability Biofeedback Intervention for First Episode Psychosis
The objective of the current study is to assess the impact of a five-week digital heart rate variability biofeedback (HRV-B) intervention or music listening on the well-being of first episode psychosis patients.
- Trial name
- NCT07628699
- Testing
- Heart Rate Variability Biofeedback, Music Listening
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- The University of Hong Kong
Alzheimer's Disease, Dementia
Optimizing Dementia Care
The purpose of this randomized controlled pilot study is to examine the preliminary effectiveness, feasibility, and potential treatment moderators (i.e., behavioral symptoms and spousal relationship status) of a newly developed…
- Conditions
- Alzheimer's Disease, Dementia, Dementia, Vascular, Caregivers
- Trial name
- ODeC (NCT02585232)
- Testing
- Counseling (C), Care Consultation (CC)
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- VA Office of Research and Development
Sleep Apnea
CPAP Adherence Pilot Study Among African Americans
The goal of the study is to determine the feasibility of a behavioral intervention to improve CPAP adherence among African American patients with obstructive sleep apnea.
- Trial name
- NCT05955287
- Testing
- Telemonitoring, Peer Based, CPAP Education
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- MetroHealth Medical Center
Hypercholesterolemia
Effects of a Chilean Diet Supplemented With Gevuina Avellana on Lipid Profile in Humans With Hypercholesterolemia
The purpose of this study is to determine if supplementing a Chilean diet with Chilean hazelnut (Gevuina avellana) improves cholesterol levels in adults with hypercholesterolemia.
- Trial name
- PRODICHI (NCT07087704)
- Testing
- High-fat diet, Low-fat diet
- Where
- Chile
- Volunteers
- 106 people
- Sponsor
- Universidad de Concepcion
Cancer, Advanced Solid Tumors, Malnutrition
A Nutrition and Exercise Program With Olanzapine Compared to Olanzapine Alone: A Trial in Patients With Advanced Tumors
Cancer patients have a higher risk of malnutrition because of their illness and treatments. This can lead to weight loss, weak muscles, less effective cancer therapy, or stronger side effects.
- Trial name
- SwissNutriAct2 (NCT07722806)
- Testing
- Standardized nutritional program, standardized exercize program, Whey protein supplement with added leucine and β-hydroxy-β-methylbutyrate (HMB)
- Where
- Switzerland
- Volunteers
- 130 people
- Sponsor
- Kantonsspital Winterthur KSW
TSC
TSC Remote Assessment and Intervention
The investigators propose a study to adapt an evidence-based caregiver training program to improve access in order to better serve the TSC community.
- Trial name
- TRAIN (NCT04698538)
- Testing
- JASPER
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of California, Los Angeles
Ovarian Cancer, Advanced Ovarian Carcinoma
REVITALIZE: RCT to Reduce Fatigue in Adults With Ovarian Cancer on PARP Inhibitors
The purpose of this study is to see whether a supportive intervention (REVITALIZE) reduces fatigue and its impact on daily life and activities for participants with ovarian cancer taking PARP inhibitors.
- Conditions
- Ovarian Cancer, Advanced Ovarian Carcinoma, Fallopian Tube Carcinoma, Primary Peritoneal Cancer
- Trial name
- NCT06710548
- Testing
- REVITALIZE Intervention, Educational Materials
- Where
- 6 sites in United States
- Volunteers
- 240 people
- Sponsor
- Dana-Farber Cancer Institute
Diabetes Mellitus, Type 2
Call-2-Health: Preventing Type II Diabetes
It is estimated that 30 million U.S. adults will have type 2 diabetes by 2050. Contributing to this national trend is the obesity epidemic.
- Trial name
- C2H (NCT01827826)
- Testing
- Telephonic intervention to prevent Diabetes Mellitus, Type 2
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Constipation - Functional, Pediatric
Comparison of Two Interventions in Children with Functional Constipation
The purpose of this study; to compare the effects of therapeutic motor control interventions and conventional treatment in children with functional constipation on symptoms, spinal posture and mobility and trunk muscles endurance.
- Trial name
- NCT05371678
- Testing
- Therapeutic motor control interventions, Conventional treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Abant Izzet Baysal University
Atopic Dermatitis
Adjunctive Group Psychotherapy for Moderate-to-Severe Atopic Dermatitis: A Pilot Feasibility Study Comparing Two Interventions
Atopic dermatitis is a chronic inflammatory skin disease characterized by eczematous skin lesions and pruritus. This partially randomized, three-arm pilot feasibility study was designed to evaluate two adjunctive group…
- Trial name
- NCT07599878
- Testing
- Stress Management and Resilience Group Therapy (SRCST), Atopic Dermatitis-specific Cognitive Behavioural and Schema Mode Group Therapy (ADCBST), standard dermatological care
- Where
- Hungary
- Volunteers
- 32 people
- Sponsor
- Semmelweis University
Primary Biliary Cholangitis
EXerCise Intervention in cholesTatic LivEr Disease: The EXCITED Study
A prospective, single centre, single-arm, pilot study investigating the safety and efficacy of a 12-week remotely-monitored home-based exercise program in patients with refractory fatigue (based on PBC-40 Quality of Life measure)…
- Trial name
- EXCITED (NCT04265235)
- Testing
- Home-based exercise program
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- University of Birmingham
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