Clinical trials: Interventions
Addiction
Just-In-Time Adaptive Interventions for Addictive Behaviors
Background: Many smartphone apps intend to help people with addictions. But not enough is known about how they should work. Researchers want to study an app that gives people the advice they need, just when they need it.
- Trial name
- NCT03538652
- Testing
- Formative Interviews (not an intervention), Cognitive-behavioral therapy (CBT), Acceptance and commitment therapy (ACT)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Antibiotic Prescribing by GPs for URTI
Developing and Evaluating Interventions to Reduce Inappropriate Prescribing of Antibiotics in Primary Care
1. Do paper-based and web-based intervention modelling experiments (the methodology we are developing) identify the same predictors of GP behaviour regarding prescribing of antibiotics for upper respiratory tract infections? 2.
- Trial name
- WIME (NCT01206738)
- Testing
- Persuasive communication, Action plan, General intervention
- Where
- United Kingdom
- Volunteers
- 270 people
- Sponsor
- University of Dundee
Trauma and Stressor Related Disorders
A Trauma-Informed Intervention for Positive Youth Development and Teacher Wellness in Rural Montana Year 2
Compared to U.S. urban counterparts, rural residents face major barriers to using health care services. Challenges include shortages of services, long distances to existing services, and stigma regarding mental illness in…
- Trial name
- NCT05844007
- Testing
- Trauma-Informed Yoga
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Montana State University
Sickle Cell Disease
Building Adaptive Coping and Knowledge to Improve Daily Life
The purpose of this study is to find out how teenagers with chronic pain and sickle cell disease respond to a new training program called Back2Life and get their feedback about how to modify the program to best fit their needs.
- Trial name
- Back2Life (NCT04602728)
- Testing
- Back2Life
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Emory University
Hypertension, Adolescent Behavior
Youth-Led Intervention to Improve Blood Pressure
The proposed study will develop, test, and collect implementation data on a youth-led hypertension (HTN) education intervention, which will act as an electronic tool to guide youth through learning and then teaching adults on how…
- Conditions
- Hypertension, Adolescent Behavior, Health Knowledge, Attitudes, Practice
- Trial name
- NCT05029687
- Testing
- Youth-Led Hypertension Education Digital Intervention
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Coronary Artery Disease
The MASS COMM Post-Randomization Phase Cohort Study
The primary objective of the Post-Randomization Phase Cohort Study is to continue to assess the safety of non-emergency PCI performed at hospitals without cardiac surgery on-site in patients with myocardial ischemia (other than…
- Trial name
- NCT02072421
- Testing
- PCI
- Where
- 10 sites in United States
- Volunteers
- 2,879 people
- Sponsor
- Baim Institute for Clinical Research
Independent Living
Implementation of CAPABLE in the Michigan Medicaid Waiver
Main study: Nearly half of older adults report problems with function, which can lead to difficulty with activities of daily living and nursing home placement.
- Trial name
- NCT03634033
- Testing
- MiCAP with IF (Main Study), MiCAP with IF and EF (Main Study), MiCAP with IF and Caregiver Engagement (Administrative Supplement)
- Where
- 18 sites in United States
- Volunteers
- 7,777 people, healthy volunteers welcome
- Sponsor
- Grand Valley State University
Pain, Depressive Symptoms
Depression and Pain Perseverance Through Empowered Recovery Intervention
African American women who are 50 years of age and older with depressive symptoms, pain and difficulty with mobility will participate in the DAPPER intervention study that includes 8 nurse visits in participants' homes to help…
- Conditions
- Pain, Depressive Symptoms, Frailty, Aging
- Trial name
- DAPPER (NCT04091347)
- Testing
- DAPPER
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Johns Hopkins University
Depression
Mindfulness Intervention to Study the Neurobiology of Depression
The Pediatric Mood Disorders Program at the University of Illinois at Chicago is conducting a research study examining how mindfulness can help teenagers stay healthy and prevent depression relapse.
- Trial name
- MIND (NCT01905267)
- Testing
- Rumination-Focused Cognitive Behavior Therapy
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Illinois Chicago
Type 2 Diabetes
Continuous Glucose Monitoring and Behavioral Change Intervention for People With Type 2 Diabetes and Diabetes Distress
The purpose of this study is to use a Personalized Trial (N-of-1) design to test the effect of an intervention that pairs continuous glucose monitoring (CGM) with text message-delivered behavior change interventions for physical…
- Trial name
- NCT05941000
- Testing
- Self-Monitoring of Behavior for Physical Activity, Action Planning for Physical Activity, Self-Monitoring of Behavior for Mood
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Palliative Care, Critical Illness
A Needs-focused Palliative Care Intervention for Older Adults in ICUs
The quality of intensive care unit (ICU)-based palliative care is highly variable, particularly for the 2 million older adults admitted annually to ICUs.
- Conditions
- Palliative Care, Critical Illness, Aging, Care Delivery Model
- Trial name
- PCplanner (NCT04414787)
- Testing
- PCplanner
- Where
- United States
- Volunteers
- 151 people
- Sponsor
- Duke University
Cancer, Survivorship
A Dyadic Intervention for Young Adult Patients With Cancer and Their Partner Caregivers
The purpose of this pilot study is to examine the feasibility and acceptability of a brief psychotherapy intervention to improve psychosocial coping and maintain couple relationships among young adults (aged 25-39) with cancer…
- Conditions
- Cancer, Survivorship, Caregiver Burden, Psychological Distress
- Trial name
- YAD (NCT06172907)
- Testing
- Young Adults Coping with Cancer Together Intervention
- Where
- 4 sites in United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Delirium, Cognitive Impairment
Family Automated Voice Reorientation Study
This randomized clinical trial tests a cognitive reorientation intervention to prevent delirium in the intensive care unit using scripted audio messages, recorded by the patient's family and played at hourly intervals during…
- Conditions
- Delirium, Cognitive Impairment, Health, Subjective, Sleep
- Trial name
- FAVoR (NCT03128671)
- Testing
- FAVoR Intervention
- Where
- 3 sites in United States
- Volunteers
- 178 people
- Sponsor
- University of Miami
Angina, Unstable, Myocardial Infarction
Dalteparin Versus Unfractionated Heparin In Patients With Acute Coronary Syndrome
To compare efficacy and safety of dalteparin compared to unfractionated heparin in patients of non ST elevation acute coronary syndromes who are planned to undergo coronary interventions (angioplasty or bypass surgery)
- Trial name
- NCT00435487
- Testing
- Dalteparin ( Fragmin), Unfractionated heparin
- Where
- 8 sites in India
- Volunteers
- 173 people
- Sponsor
- Pfizer
Mental Health Issues, Bipolar Disorder
Music Therapy Advocacy Recording Intervention (MTAR) on Internalized Stigma
This study will use a systematic music therapy intervention on patients with mental illness trying to help them with their internalized stigma.
- Conditions
- Mental Health Issues, Bipolar Disorder, Depressive, Schizophrenia Spectrum and Other Psychotic Disorders
- Trial name
- NCT05723328
- Testing
- Group Music Therapy Advocacy Recording Intervention (MTAR)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Hackensack Meridian Health
Schizoaffective Disorder, Schizophrenia
Effectiveness of a Mobile Texting Intervention for People With Serious Mental Illness
Testing an mHealth mobile interventionist texting program on illness management.
- Conditions
- Schizoaffective Disorder, Schizophrenia, Bipolar Disorder, Major Depressive Disorder
- Trial name
- NCT03062267
- Testing
- Mobile Interventionist
- Where
- 2 sites in United States
- Volunteers
- 49 people
- Sponsor
- University of Washington
Multiple Sclerosis
Tele-Exercise and Multiple Sclerosis
The purpose of this study is to compare the effects of two delivery models of an evidence-based complementary alternative medicine (CAM) program that combines neurorehabilitative (functional) exercise, yoga, and Pilates for…
- Trial name
- TEAMS (NCT03117881)
- Testing
- DirectCAM, TeleCAM, rDirectCAM
- Where
- 40 sites in United States
- Volunteers
- 911 people
- Sponsor
- University of Alabama at Birmingham
HIV
Mobile Health Intervention to Increase HIV Testing and Linkage to Care
This 5-year project will test an mobile health approach to improve HIV self-testing (HST) and linkage to HIV-related care among high-risk men in China.
- Trial name
- NCT05484895
- Testing
- WeTest-WeLink, Control condition
- Where
- 3 sites in China
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Emory University
Diabetes Mellitus, Type 2
mHealth Intervention to Support Diabetes Medication Adherence
This study aims at evaluating the effectiveness of an intervention based on the use of a mobile-device based system delivering automated, tailored brief text messages to offer support for medicine use and lifestyle…
- Trial name
- DIABE-TEXT (NCT05006872)
- Testing
- DIABE-TEXT
- Where
- Spain
- Volunteers
- 742 people
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Locally Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm
PLAN Intervention to Enhance Engagement of Latino Cancer Patients in Advanced Care Planning
This trial tests whether Planning for Your Advance Care Needs (PLAN) intervention works to enhance Latino patients' understanding of and engagement in advanced care planning.
- Trial name
- NCT04889144
- Testing
- Communication Intervention, Best Practice, Questionnaire Administration
- Where
- 4 sites in United States
- Volunteers
- 27 people
- Sponsor
- Fred Hutchinson Cancer Center
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