Clinical trials: Interventions
Intervention Studies, ASA Physical Status I
Biological, Radiographic and Clinical Evaluation of Various Inter-Visit Root Canal Dressings in Retreatment Cases
The aim of this clinical trial is to evaluate anti-inflammatory effect of various intracanal medications: 1. Calcium Hydroxide Slurry mixed with 3% Sodium Hypochlorite 2. Calcium Silicate 3.
- Conditions
- Intervention Studies, ASA Physical Status I, Intracanal Medication, Periapical Abscess
- Trial name
- RCT (NCT07641933)
- Testing
- Calcium Silicate Intracanal Medication, Calcium Hydroxide Slurry mixed with Sodium Hypochlorite Intracanal Medication, Calcium Hydroxide (Ca(OH)2) Intracanal Medication
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Frailty
Feasibility of a Multidisciplinary Student-Led Program to Improve Frailty in Nursing Home Residents
BACKGROUND Frailty, regarded as a potentially reversible process and defined as a progressive deterioration of physiological systems and intrinsic capacity, constitutes a key risk factor for disability, dependency and…
- Trial name
- CUIDAFRAIL (NCT07182747)
- Testing
- Nursing students' intervention programme, Standard care from Public Andalusian Health Service
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Universidad de Almeria
Neck Pain
The Comparative Effectiveness of Interventions in People With Neck Pain Who Exhibit Directional Preference
The goal of this clinical trial is to compare physical therapy treatments in people with neck pain. The main aim is to compare the short-term effectiveness of physical therapy treatment for neck pain as delivered through…
- Trial name
- NCT06160648
- Testing
- Management according to Mechanical Diagnosis and Therapy, Management according to the Cervical Spine Clinical Practice Guidelines
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- Tufts University
Internet Use Disorders
Intervening in Problematic Internet Use
The present study examines the efficacy of a brief intervention for problematic Internet use based on Motivational Interviewing (MI) and Cognitive Behavioral Therapy (CBT) in a sample of students screened proactively in…
- Trial name
- iPIN (NCT03646448)
- Testing
- Motivational Interviewing
- Where
- Germany
- Volunteers
- 470 people
- Sponsor
- University of Luebeck
Exercise Induced Laryngeal Obstruction (EILO)
Managing Dysfunctional Breathing and Exercise-induced Laryngeal Obstruction in Adolescent Athletes
This study aimed to assess if a multidimensional individually tailored intervention, including Norwegian Psychomotor Physiotherapy (NPMP), elements of cognitive behavioural therapy and a rehabilitation plan, helped reduce…
- Trial name
- NCT06033755
- Testing
- Norwegian psychomotor physiotherapy
- Where
- Norway
- Volunteers
- 18 people
- Sponsor
- VID Specialized University
Hand Hygiene, Handwashing Behaviour
Hands4Health: A Multi-component Intervention on Hand Hygiene & Well-being in Schools in Nigeria & Palestine (H4H)
The aim of this study is to assess the impact of the hands4health hand hygiene multi-component intervention on students and teachers in primary schools with limited access to water in Nigeria and Palestine.
- Conditions
- Hand Hygiene, Handwashing Behaviour, Well-Being
- Trial name
- H4H (NCT05964478)
- Testing
- Multi-component hand hygiene intervention in primary schools not connected to functional water supply system in Nigeria and Palestine
- Where
- 2 sites in Nigeria, Palestinian Territories
- Volunteers
- 2,600 people, healthy volunteers welcome
- Sponsor
- Swiss Tropical & Public Health Institute
Hemorrhoids, Surgery
Impact of Moderate to Severe Pain in the Post-intervention Monitoring Room After Hemorrhoidectomy on the Length of Stay in the Outpatient Surgery Unit
The target rate for outpatient surgery has been set by the Ministry of Health at 70% for 2020. To achieve this objective, this requires increasing the panel of eligible outpatient procedures to more mutilating surgeries and…
- Trial name
- HEM_DOULEUR (NCT04567485)
- Where
- France
- Volunteers
- 446 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Stroke, Transient Ischemic Attack
Tailored Intervention to Improve Patient Adherence to Secondary Stroke Prevention Medication
Patient suffering a Transient Ischemic Attack (TIA) or stroke are subsequently at high risk of a new stroke, however, poor adherence to secondary prevention medications occurs frequently within this patient group.
- Trial name
- NCT01684176
- Testing
- Complex tailored intervention, Usual care
- Where
- Denmark
- Volunteers
- 211 people
- Sponsor
- Odense University Hospital
Food Preferences, Obesity
Vending Labeling Sales and Intercepts Study
The aim of this study is to compare the impact of 4 different types of front of package (FOP) food and beverage messages: 1) green labels on healthy foods, 2) red/yellow/green labels on less healthy/moderately healthy/healthy…
- Conditions
- Food Preferences, Obesity, Weight Gain
- Trial name
- NCT06260176
- Testing
- exposure to healthy labels only, exposure to healthiness information, exposure to physical activity equivalents
- Where
- United States
- Volunteers
- 1,065 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Dementia, Family Caregiver
German Adaptation of REACH II
The purpose of the present study is to adapt, to implement and to evaluate an support program for family caregivers of patients suffering from Alzheimers'Disease (AD).
- Trial name
- GE-REACH (NCT01690117)
- Testing
- GE-REACH-program
- Where
- Germany
- Volunteers
- 92 people
- Sponsor
- University of Leipzig
COVID-19
Puerto Rico COVID-19 Vaccine Uptake Study
The purpose of this study is to recruit a total of 386 participants to evaluate the effectiveness of an educational program to increase the proportion of men and women aged 21 years and older who have received the COVID-19…
- Trial name
- PR-COVACUPS (NCT05468021)
- Testing
- Educational intervention
- Where
- 2 sites in Puerto Rico
- Volunteers
- 394 people, healthy volunteers welcome
- Sponsor
- University of Puerto Rico
Bacteremia, Sepsis
Impact of Rapid Pathogen Identification From Blood Cultures (RABbIT)
Septic shock carries high mortality, which may be exacerbated by inappropriate initial therapy. Inappropriate therapy may result from unanticipated antimicrobial resistance.
- Conditions
- Bacteremia, Sepsis, Fungemia, Blood Stream Infection
- Trial name
- RABbIT (NCT02743585)
- Testing
- Filmarray Blood Culture ID (BCID) panel, Rosco Diagnostica ESBL/carbapenemase screen kit
- Where
- Singapore
- Volunteers
- 832 people
- Sponsor
- Tan Tock Seng Hospital
Smoking Cessation
Extended Treatment for Smoking Cessation
Adult smokers (21-65) and adolescent smokers (18 - 21) years of age residing in Alameda and Santa Clara counties will serve as the target population for this study.
- Trial name
- NCT01330043
- Testing
- Bupropion, Nicotine patch, Varenicline
- Where
- United States
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obesity and Overweight
Smart Nutrition, Healthier Communities
The project investigates the effect of the health app Lifeness as a digital therapeutic (DTx) and follow-up tool in a municipal setting at a regional Healthy Lives Center in central Norway (Frisklivssentralen Værnesregionen)…
- Trial name
- NCT06667843
- Testing
- Lifestyle Management, Intervention, Control
- Where
- 2 sites in Norway
- Volunteers
- 37 people
- Sponsor
- Norwegian University of Science and Technology
Alcohol Use, Alcohol Drinking
Young Adult Naturalistic Alcohol Study (YANAS) Using Smartphone Technology in a Simulated Laboratory Environment
It is important to explore use of technology to reduce drinking. The purpose of this research study is to compare different types of mobile technology for their effects on alcohol drinking and ratings of usability among young…
- Conditions
- Alcohol Use, Alcohol Drinking, Drinking Behavior
- Trial name
- NCT02841735
- Testing
- Smartphone breathalyzer device/app use, BAC estimator app use, Text messaging procedure
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Florida
Coronary Artery Disease, Percutaneous Coronary Intervention
Study of the Long-term Effects of P2Y12 Inhibitor Monotherapy and Coagulation Markers After Percutaneous Coronary Angioplasty.
Patients who undergo percutaneous coronary intervention (PCI) are commonly treated with antiplatelet therapy to prevent stent thrombosis and recurrence of events.
- Conditions
- Coronary Artery Disease, Percutaneous Coronary Intervention, Acute Coronary Syndromes, Antiplatelet Therapy
- Trial name
- HI-TECH 2 (NCT07582835)
- Testing
- Clopidogrel, Ticagrelor, Prasugrel
- Where
- Switzerland
- Volunteers
- 355 people
- Sponsor
- Cardiocentro Ticino
Dating Violence, Dating Abuse
A Brief Intervention
This randomized controlled trial (RCT) study is a small scale test of the feasibility and preliminary efficacy of a brief motivational interview-style intervention.
- Trial name
- NCT01632176
- Testing
- Brief, motivational interview and one booster session
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Boston University
Type 2 Diabetes
Effectiveness of an Online Self-management Intervention for Type 2 Diabetes Mellitus
This trial was designed to evaluate the effectiveness of the dialogue-based online intervention covivio, which was designed to improve diabetes self-management in patients with type 2 diabetes.
- Trial name
- OnSeT-2D (NCT05525117)
- Testing
- covivio (additional to treatment as usual), treatment as usual
- Where
- Germany
- Sponsor
- Gaia AG
Breast Cancer
Evaluating a Novel Web-based Intervention for Breast Cancer Survivors
The trial aims to evaluate the effectiveness of a novel web-based intervention (Optimune), which was designed to introduce relevant cognitive-behavioral therapy (CBT) techniques to women with breast cancer who are past the active…
- Trial name
- OPTIMUNE (NCT03643640)
- Testing
- Optimune, Care-As-Usual
- Where
- 2 sites in Germany
- Volunteers
- 360 people
- Sponsor
- Technical University of Dortmund
Sleep, Pain
A Personalized Behavioral Intervention for Older Adults With Musculoskeletal Pain and Sleep Complaints
It is well recognized that physical activity/exercise is an effective intervention to improve sleep, reduce pain and improve function in a variety of pain conditions.
- Trial name
- NCT03921840
- Testing
- ELDERFITNESS, Control
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
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