Clinical trials: Interventions
Diabetes Mellitus, Type 2, Diet, Healthy
CTSI Pilot: Improving Adherence to Diabetic Diet
425 million adults live with diabetes worldwide, and the prevalence of Type 2 diabetes is rising. Dietary approaches are recommended for weight control and diabetes management, but modern environments, characterized by plentiful…
- Conditions
- Diabetes Mellitus, Type 2, Diet, Healthy, Pre-diabetes
- Trial name
- NCT04051008
- Testing
- Online - use of online grocery shopping platform, Default - use of online grocery shopping platform with default shopping carts
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- State University of New York at Buffalo
Physical Activity, Exercise
Be-Active Study - Increasing Physical Activity in Cancer Survivors
Rates of cancer survivorship are on the rise and cancer survivors face unique health challenges that are common across cancer types that last well beyond the cessation of cancer treatment (e.g., increased fatigue…
- Conditions
- Physical Activity, Exercise, Cancer Survivors
- Trial name
- NCT05376293
- Testing
- Behavioral Internet program, Informational newsletter condition
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Family Mindfulness-based Intervention in War-affected Families, Intergenerational Trauma
FMBI With War-affected Families
This study has two central research questions: 1) Is implementing a family mindfulness-based intervention with war-affected immigrant families through community based participatory research methods feasible?; and 2) Does the…
- Conditions
- Family Mindfulness-based Intervention in War-affected Families, Intergenerational Trauma, War-Related Trauma
- Trial name
- NCT05241314
- Testing
- Learning to BREATHE, After Deployment Adaptive Parenting Tools (ADAPT)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Nicotine Dependence
Study Two on the Effectiveness of Mindfulness Training for Smokers
The MTS2 study enrollment goal is N=240 adult smokers randomized to study treatments. The study design includes two randomized arms to compare matched intensive interventions and a third non-randomized option for participants who…
- Trial name
- MTS2 (NCT01299909)
- Testing
- Integrated Training for Smokers, Mindfulness Training for Smokers, Quitline
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- University of Wisconsin, Madison
Stem Cell Transplantation, Myelodysplastic Syndromes
Electronic Health Mindfulness-based Music Therapy Intervention for Patients Undergoing Allogeneic Stem Cell Transplantation
The goal of this study is to pilot test an Electronic Health Mindfulness-based Music Therapy Intervention (eMBMT) intervention to improve health-related quality of life (HRQoL) and reduce symptom burden of patients undergoing…
- Conditions
- Stem Cell Transplantation, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma
- Trial name
- NCT05968963
- Testing
- Mindfulness-based Music Therapy (MBMT), Mindfulness Meditation (MM)
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Miami
Coronavirus, Covid19
N-Acetyl Glucosamine as Therapeutic Intervention for Coronavirus Disease-19 (COVID-19)
This study examines the efficacy of N-acetylglucosamine (NAG) in treating patients with novel coronavirus (COVID-19) infection.
- Trial name
- NCT04706416
- Testing
- N-acetyl glucosamine (NAG), Control
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Quantinosis.ai LLC
Distress, Caregiver
Tailored Health Self-Management Interventions for Highly Distressed Family Caregivers
How do varying levels of participation in selecting self-management interventions (ranging from no input into the selection to selection based on need or preference) affect health risks and physical and mental health over time in…
- Trial name
- NCT03023332
- Testing
- Resourcefulness Training, Biofeedback training, Bipolar Education
- Where
- United States
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Dementia Caregiving
Stress Reduction Study for Partners of Early Stage Dementia
This is a study designed to pilot a WOOP (Wish Outcome Obstacle Plan) intervention for spouses of persons with early stage dementia for the purposes of future research. The investigators will be using two cohorts.
- Trial name
- NCT03691428
- Testing
- Wish Outcome Obstacle Plan
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Yale University
Posttraumatic Stress Disorder, Anger
Mobile Intervention for Veterans With PTSD and Anger
Anger is the mostly commonly reported reintegration concern among combat Veterans, especially those with PTSD. Problematic anger is associated with significant functional impairment.
- Trial name
- NCT03733028
- Testing
- Mobile Intervention for Reducing Anger (MIRA), Mindfulness Intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- VA Office of Research and Development
Traumatic Brain Injury, Alexithymia
The Emotion Builder: An Intervention for Emotional Deficits After Brain Injury
The purpose of this study is to examine a web-based training program for treating emotional problems in people who have suffered a traumatic brain injury (TBI).
- Trial name
- NCT02432300
- Testing
- Emotion Builder
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- EmotEd
Congestive Heart Failure, Emotions
Researching Emotions And Cardiac Health (REACH): Phase II
The focus of this study is to examine the feasibility, acceptability, and preliminary impact of our customized positive psychology (PP)-based health behavior intervention in a group of patients with mild to moderate heart failure…
- Conditions
- Congestive Heart Failure, Emotions, Patient Compliance
- Trial name
- REACH II (NCT02938052)
- Testing
- PP-based health behavior intervention
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Massachusetts General Hospital
HIV, AIDS
Personalized Text Messages to Improve Antiretroviral Treatment (ART) Adherence in HIV+ Methamphetamine Users
Methamphetamine (METH) is a debilitating and frequently abused substance that is often comorbid with HIV infection. HIV+ persons with current METH abuse or dependence (HIV+/METH+) have several characteristics, in addition to…
- Trial name
- iTAB (NCT01317277)
- Testing
- individualized Texting for Adherence Building (iTAB), Psychoeducation
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of California, San Diego
Neoplasms, Cancer
An Evaluation of the Families Addressing Cancer Together (FACT) Intervention
This is a pilot feasibility and acceptability study to inform the development and testing of a novel communication intervention to support parents in their communication with children about cancer.
- Conditions
- Neoplasms, Cancer, Parenting, Communication
- Trial name
- FACT (NCT04342871)
- Testing
- FACT
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Morbid Obesity
Surgical Intervention in Bariatric Patients: Excess Weight Loss in the Morbidly Obese Following Gastric Plication
Up to 45 men and women who meet the entry criteria will undergo the gastric plication procedure. The study will assess subject excess weight loss (%EWL) following the study procedure at 1, 3, 6, 12, 18, 24, 30 and 36 months.
- Trial name
- NCT01077193
- Testing
- Gastric Plication
- Where
- 3 sites in United States, Czechia
- Volunteers
- 44 people
- Sponsor
- Ethicon Endo-Surgery
Autism Spectrum Disorder, Autistic Disorder
A Folinic Acid Intervention for Autism Spectrum Disorders
Researchers at Arkansas Children's Hospital Research Institute are conducting a study looking at the effects of Folinic Acid on language in Autism Spectrum Disorder and language impairment. The study has 3 phases.
- Conditions
- Autism Spectrum Disorder, Autistic Disorder, Autism, Asperger's Syndrome
- Trial name
- NCT01602016
- Testing
- Folinic Acid
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- University of Arkansas
HIV/AIDS, Tuberculosis
Drinkers' Intervention to Prevent Tuberculosis (DIPT Study)
There is an urgent global need to decrease the high mortality of tuberculosis (TB) in persons with HIV as TB is the leading cause of death among persons with HIV worldwide.
- Trial name
- DIPT (NCT03492216)
- Testing
- Incentives for negative EtG test, Incentives for positive IsoScreen test
- Where
- 2 sites in Uganda
- Volunteers
- 680 people
- Sponsor
- University of California, San Francisco
Overweight, Obesity
Mothers in Motion Program to Prevent Weight Gain in WIC Mothers (MIM)
Mothers in Motion will draw on the successes of the pilot intervention of the same name and will promote healthy lifestyle behavior changes (eating more fruits and vegetables, increasing physical activity, dealing with stress) in…
- Trial name
- MIM (NCT01839708)
- Testing
- Lifestyle Counseling
- Where
- 2 sites in United States
- Volunteers
- 569 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Diabetic Nephropathy
Nephropathy In Type 2 Diabetes and Cardio-renal Events
The NID-2 study, a multicentric study (21 centres enrolled), was planned in two phases: Phase 1(observational study, completed in September 2005): after the identification of a type-2 diabetic population with typical Diabetic…
- Trial name
- NID-2 (NCT00535925)
- Testing
- SoC therapy, irbesartan, ramipril
- Where
- Italy
- Volunteers
- 850 people
- Sponsor
- University of Campania Luigi Vanvitelli
Stroke, Ischemic
A Study of the Use of the Q Aspiration Catheter to Remove Clot in Stroke Patients
The purpose of this study is to collect real-world safety and performance data on the MIVI Neuroscience, Inc. Q Aspiration Catheter for use in the removal of fresh, soft emboli and thrombi in the neurovascular system during acute…
- Trial name
- TAPAS (NCT04089917)
- Testing
- Q Aspiration Catheter
- Where
- 4 sites in Spain
- Volunteers
- 45 people
- Sponsor
- MIVI Neuroscience, Inc.
Chronic Pain
Reaching Rural Veterans: Applying Mind-Body Skills for Pain Using a Whole Health Telehealth Intervention - UG3 Pilot Study
This project addresses the significant challenge of providing evidence-based non-pharmacologic pain management to rural-dwelling Veterans in the VA healthcare system who have chronic pain.
- Trial name
- RAMP-Pilot (NCT06568250)
- Testing
- RAMP program
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Minneapolis Veterans Affairs Medical Center
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