Clinical trials: Interventions
Anhedonia
Development of a Novel Transdiagnostic Intervention for Anhedonia - R33 Phase
The overall goal of this project is to develop a novel transdiagnostic treatment for anhedonia, called Behavioral Activation Treatment for Anhedonia (BATA), using ultra-high field functional neuroimaging.
- Trial name
- NCT04036136
- Testing
- Behavioral Activation, Mindfulness Treatment
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- University of North Carolina, Chapel Hill
Diabetes Mellitus, Type 2
Diabetes Prevention Program Lifestyle Intervention in the Marshallese Population
The investigators will conduct a comparative effectiveness cluster-randomized controlled trial (cRCT) of two Diabetes Prevention Program (DPP) lifestyle interventions: a faith-based intervention (Wholeness, Oneness…
- Trial name
- NCT03270436
- Testing
- Wholeness, Oneness, Righteousness, Deliverance Diabetes Prevention Program, Partnership for Improving Lifestyle Intervention Diabetes Prevention Program
- Where
- United States
- Volunteers
- 380 people
- Sponsor
- University of Arkansas
Multiple Sclerosis
An Individualized-health eLibrary App for People With Multiple Sclerosis
The purpose of this study is to assess the effectiveness after using a new individualized-health e-library app named SavvyHealth among people with multiple sclerosis.
- Trial name
- SavvyHealth (NCT05124600)
- Testing
- SavvyHealth
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Illinois at Urbana-Champaign
Schizophrenia, Bipolar Disorder
App and Body Fat Scale in the Management of Overweight Patients
This study tests whether using a health app (Huawei Health) and a smart body fat scale can help overweight patients with schizophrenia or bipolar disorder lose weight and stay engaged in their health. What We're Testing: 1.
- Conditions
- Schizophrenia, Bipolar Disorder, Metabolic Syndrome, Overweight and Obesity
- Trial name
- NCT05866107
- Testing
- Effectiveness and Feasibility of Self-Monitoring for Weight Management in Individuals with Mental Disorders Using Digital Intervention ("SWIM" trial)
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Capital Medical University
Fibromyalgia
Efficacy of NAT-FM Treatment for Fibromyalgia
The main objective of this study is to analyse the efficacy of the NAT-FM multicomponent treatment program as coadjuvant of treatment-as-usual (TAU) compared to TAU alone.
- Trial name
- NAT-FM (NCT04190771)
- Testing
- TAU + multicomponent treatment NAT-FM, Treatment as Usual (TAU)
- Where
- Spain
- Volunteers
- 169 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Posttraumatic Stress Disorder
Examining an Emergency Room Intervention for the Prevention of Post Traumatic Stress Disorder (PTSD)
PTSD is a common and distressing possible outcome following exposure to a traumatic event. Recent studies show that memory processes may be central to the development of the disorder, and interrupting the consolidation of…
- Trial name
- NCT01162044
- Testing
- Computer game
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Cancer
Personalized Alerts and Care Pathways to Prompt Prevention Interventions for Alcohol and Tobacco Users in Primary Care
Tobacco and alcohol use present multiplicative risk for aerodigestive cancers. Reducing alcohol consumption improves smoking cessation outcomes and reduces cancer risk.
- Trial name
- COMBAT (NCT03108144)
- Testing
- Brief alcohol intervention
- Where
- Canada
- Volunteers
- 15,222 people
- Sponsor
- Centre for Addiction and Mental Health
Irreversible Pulpitis, Reversible Pulpitis
Treatment of Deep Carious Lesions With Selective Caries Removal, Partial or Full Pulpotomy
The optimal treatment of deep caries lesions extended to the inner third of dentin is still under discussion. Cariologists prefer selective caries removal, meanwhile endodontists recommend partial pulpotomy.
- Conditions
- Irreversible Pulpitis, Reversible Pulpitis, Dentine Caries
- Trial name
- Vitapulp (NCT04807244)
- Testing
- Selective Caries Removal with Biodentine™, Partial Pulpotomy with Biodentine™, Full Pulpotomy with Biodentine™
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Bipolar Disorder Family Members
A Psychoeducation Intervention for Caregivers of Patients With Bipolar Disorder
Bipolar disorder is a debilitating chronic illness characterized by periods of elation and depression. Since deinstitutionalization of the mentally ill over 40 years ago, families have become major caregivers for patients with…
- Trial name
- NCT02446509
- Testing
- Psychoeducation, Psychoeducation - Delayed
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Spinal Cord Injuries
FES-assisted Gait Intervention in People with Spinal Cord Injury - Pilot Study
A spinal cord injury (SCI) disrupts the communication within the nervous system, leading to limitations in sensorimotor activities such as walking.
- Trial name
- NCT05908175
- Testing
- FES-assisted gait training
- Where
- Netherlands
- Volunteers
- 5 people
- Sponsor
- Stichting Reade
Child Development
Effects of Music Intervention on the Brain Development of Preschool Children
The purpose of this research study is to learn more about the effects a musical intervention has on typical brain development in preschool-aged children.
- Trial name
- NCT01275001
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Avera McKennan Hospital & University Health Center
Mindfulness, Caregivers
Dyadic Mindfulness for People With Parkinson's Disease and Their Caregivers
The proposed two-arm randomized waitlist-controlled trial will use a mixed-methods design to investigate the effects of dyadic mindfulness on physio-psycho-spiritual outcomes in people with Parkinson's Disease (PwPD) and their…
- Conditions
- Mindfulness, Caregivers, Movement Disorders, Neurodegenerative Disease
- Trial name
- NCT06821230
- Testing
- Dyadic mindfulness
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- The University of Hong Kong
Edentulism Complete, Denture, Complete
Nutritional Intervention for Older Adults With Complete Dentures
The purpose of this clinical trial is to test a nutritional intervention. This study helps older adults who wear complete removable dentures improve their health.
- Conditions
- Edentulism Complete, Denture, Complete, Mastication Disorder
- Trial name
- NCT07692828
- Testing
- Nutritional Intervention
- Where
- Chile
- Volunteers
- 40 people
- Sponsor
- Universidad de La Frontera
Smoking Cessation
Alaska Native Family-Based, Financial Incentives Intervention for Smoking Cessation
The objective of the proposed study is to develop and beta-test a culturally adapted, Alaska Native family-based incentives intervention for smoking cessation.
- Trial name
- Aniqsaaq (NCT05413265)
- Testing
- Phases 1 and 2
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Mayo Clinic
Dementia
The INSPIRE -Faith Study: Intervention Strategies for Preserving Intellectual Resilience and Engagement
The INSPIRE-Faith Study, initiated by the Healthy Minds Initiative, is a community-based research project aimed at demonstrating the impact of lifestyle factors on cognitive health and the prevention of dementia.
- Trial name
- INSPIRE -Faith (NCT06741865)
- Testing
- Lifestyle Intervention, Standard Health Education
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Healthy Minds Initiative
Alcohol-Related Disorders
Alcohol & Exercise Study
The goal of this clinical trial is to learn if exercise can reduce alcohol craving in heavy social alcohol drinkers. The main questions this project aims to answer are 1) compared to a distraction activity (i.e., coloring), will…
- Trial name
- Alc-Excr (NCT05955911)
- Testing
- Exercise, Coloring
- Where
- Canada
- Volunteers
- 68 people
- Sponsor
- Western University, Canada
Suicide
THRIVE: A Recovery-Focused Suicide Prevention Intervention in Crisis Stabilization Centers
Suicide is a major public health concern in the United States, with more than 1.4 million adults attempting suicide and nearly 50,000 adults dying by suicide each year.
- Trial name
- THRIVE (NCT07784634)
- Testing
- Toward Hope, Recovery, Interpersonal Growth, Values, and Engagement (THRIVE), Center Care as Usual
- Where
- 3 sites in United States
- Volunteers
- 552 people
- Sponsor
- University of Alabama at Birmingham
Radial Artery
Oximetry Guided Versus Traditional Rapid Deflation Technique for Achieving Hemostasis After Radial Procedures
After performing a radial angiography/percutaneous coronary intervention (CAG/PCI), the sheath is removed and a compression device is used to achieve hemostasis.
- Trial name
- ACCESS-III (NCT03626129)
- Testing
- Oximetry guided deflation
- Where
- Denmark
- Volunteers
- 3,600 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital Skejby
Smoking Cessation
Early Health Warning Intervention in Tobacco Control
This is a multi-center, randomized, controlled intervention clinical trial. A total of 1000 current smokers with rapid decline in lung function will be recruited and equally divided into two groups, comprehensive smoking…
- Trial name
- NCT04996329
- Testing
- early health warning intervention
- Where
- 10 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Endometriosis, Pain
Is Repetitive Transcranial Magnetic Stimulation Effective in Reducing Endometriosis-associated Pain
The goal of this research is to improve pain outcomes for the over 500K Canadian women, girls and gender-diverse individuals who are newly diagnosed with endometriosis each year.
- Trial name
- NCT06333353
- Testing
- Real RepetitiveTranscranial Magnetic Stimulation 5 sessions, Real RepetitiveTranscranial Magnetic Stimulation 10 sessions
- Where
- Canada
- Volunteers
- 152 people
- Sponsor
- University of Ottawa
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