Clinical trials: Interventions
Multiple Sclerosis
Testing the Efficacy of Self-Generation Treatment Protocol
Past research has shown that items self-generated by an individual, such as words or concepts, are remembered better than items that are simply read or heard.
- Trial name
- NCT02032589
- Testing
- Self-generation treatment
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Kessler Foundation
Alzheimer Disease, Early Onset, Parkinsons Disease with Dementia
Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease
The goal of this Multicenter observational pilot study is to Compare the specifics of musical engagement (behaviors related to music in everyday life) in subjects aged over 60 with Alzheimer s disease, Parkinson s disease and…
- Conditions
- Alzheimer Disease, Early Onset, Parkinsons Disease with Dementia, Non Pharmacological Intervention
- Trial name
- MUSENGAGE (NCT06688968)
- Testing
- neuropsychologist interview, questionnaire
- Where
- 3 sites in France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Death Anxiety
The Effectiveness of an Online Self-Delivered Death Anxiety Intervention
The goal of this clinical trial is to examine the effectiveness of the online self-delivered death anxiety intervention developed by our team in the general population with a randomized controlled trial.
- Trial name
- NCT06801132
- Testing
- Online self-delivered death anxiety intervention, Waiting-List (WL) condition
- Where
- China
- Volunteers
- 47 people
- Sponsor
- Peking University
Interstitial Lung Disease (ILD), Fibrotic Interstitial Lung Disease
Optimizing the Follow-Up Journey in Interstitial Lung Disease: The OPTIMIZE-ILD-2 Trial
The OPTIMIZE-ILD-2 trial is a prospective, randomized, open-label clinical trial designed to evaluate the impact of a coordinated follow-up pathway on patients with established interstitial lung disease (ILD).
- Conditions
- Interstitial Lung Disease (ILD), Fibrotic Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis (IPF), Progressive Pulmonary Fibrosis
- Trial name
- OPTIMIZE-ILD-2 (NCT07486206)
- Testing
- Standard ILD Follow-Up Pathway, Optimized One-Day ILD Follow-Up Circuit
- Where
- Spain
- Volunteers
- 152 people
- Sponsor
- Hospital de Granollers
Acquired Adult Flatfoot Deformity, Flat Foot
Sinus Tarsi Implant as an Adjuvant Procedure to Medial Displacement Calcaneal Osteotomy in the Treatment of Mobile Adult Acquired Flatfoot Deformity
Background: Adult acquired flatfoot deformity (AAFD) is a deformity of the foot which leads to pain and an altered gait pattern. There are several different surgical interventions available for treatment of AAFD.
- Conditions
- Acquired Adult Flatfoot Deformity, Flat Foot, Flexible Flatfoot
- Trial name
- NCT06211504
- Testing
- ProStop, sinus tarsi implant (STI), Conventional surgery
- Where
- 10 sites in Sweden
- Volunteers
- 130 people
- Sponsor
- Region Skane
Maternal Death Affecting Fetus or Newborn, Delivery Complication
Impact of a Smartphone Intervention on Tanzanian Women's Childbirth Location
This study investigates whether training Community Health Workers (CHW) to use a smartphone-based prenatal counseling application as a "job aid" instead of the existing paper based standard is associated with increased women's…
- Conditions
- Maternal Death Affecting Fetus or Newborn, Delivery Complication, Obstetric Complication, Birth Injuries
- Trial name
- SUSTAIN1 (NCT03161184)
- Testing
- SUSTAIN Smartphone training of CHW (SP+), SUSTAIN Paperbased training of CHW (SOC)
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Refractive Error, Visual Impairment
The Baltimore Reading and Eye Disease Study
The Baltimore Reading and Eye Disease Study (BREDS) is a two year study to determine the prevalence of vision problems in an early school age population with reading difficulty.
- Conditions
- Refractive Error, Visual Impairment, Convergence Insufficiency, Reading Disabilities
- Trial name
- BREDS (NCT02607384)
- Testing
- Eyeglass wearing, Orthoptic exercises, Specialist referral
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Schizophrenia, Psychotic Disorders
Medication Adherence in Schizophrenia: Development of a CBT-Based Intervention
This is a randomized pilot study of an intervention based on principles of Cognitive Behavioral Therapy (CBT). This intervention is the Health Dialogue Intervention (HDI) and will be compared to a traditional medical model of…
- Trial name
- NCT00980252
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Illinois Chicago
Mitral Valve Regurgitation
Hemodynamic Stress Test in Severe Mitral Regurgitation (HEMI)
The preferred treatment of organic mitral regurgitation (MR) is mitral valve repair. Optimally this should be timed so late that it commensurate with the risk of surgery and before irreversibly damage of the heart and pulmonary…
- Trial name
- HEMI (NCT02961647)
- Testing
- Mitral valve repair
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Odense University Hospital
Opioid-use Disorder
Disclosure Intervention for People in Recovery From Opioid Use Disorder
Many people with substance use disorders struggle with decisions regarding whether to disclose to others that they have a history of substance use and/or are in recovery.
- Trial name
- NCT04836247
- Testing
- Disclosing Recovery: A Decision Aid and Toolkit, Mindfulness
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Delaware
Percutaneous Coronary Intervention
Radial Artery Patency and Bleeding, Efficacy, Adverse evenT Trial
The objectives of this study are to demonstrate the safety and efficacy of the new 6Fr sheath (Glidesheath slender; Terumo, Tokyo,Japan ; GSS) compared with the contemporary 5Fr sheath (Hydrophilic coating sheath from Terumo…
- Trial name
- RAPandBEAT (NCT02269449)
- Testing
- 6Fr Glidesheath Slender sheath, 5Fr sheath, Hemostasis with TR band
- Volunteers
- 1,900 people
- Sponsor
- NPO International TRI Network
Type 2 Diabetes, Self-regulation
Building Self-regulation Capacity in AA T2DM Women: Feasibility of EMI
In African-Americans, the incidence of type 2 diabetes (T2DM) is ~14%. Adherence to crucial diabetes self-management (DSM) behaviors, such as engaging in physical activity (PA) is dangerously low among AA women living in…
- Trial name
- NCT04083248
- Testing
- Feasibility group
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Illinois Chicago
Malaria,Falciparum, Gametocytes
Controlled Human Malaria Infection Model for Evaluation of Transmission-blocking Interventions - Study 2
This is a single-center, open label study. The primary aim of this project is to develop a controlled human malaria infection transmission model ("CHMI-trans") or "challenge model" to evaluate the capacity of vaccines, biologics…
- Conditions
- Malaria,Falciparum, Gametocytes, Controlled Human Malaria Infection, Transmission
- Trial name
- CHMI-trans2 (NCT03454048)
- Testing
- Piperaquine (low dose), Piperaquine (high dose), Sulfadoxine pyrimethamine
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Percutaneous Coronary Intervention
Comparative Registry of the PROmus™, ENdeavor™ and CYpher™ Drug Eluting Stents
The purpose of this study is to collect real-life data of the Promus™ stent, the Cypher™ stent and the Endeavor™ stent in routine clinical practice, and compare outcomes.
- Trial name
- ProEnCy (NCT00930878)
- Testing
- Cardiac Stenting
- Where
- Germany
- Volunteers
- 1,934 people
- Sponsor
- Boston Scientific Corporation
Inflammatory Arthritis
Examining the Efficacy of Personalized Lifestyle Intervention in Individuals With Rheumatoid Arthritis
It is aimed to examine the effects of person-centered lifestyle intervention on occupational performance, general health status, and quality of life in individuals with rheumatoid arthritis.
- Trial name
- NCT05759585
- Testing
- person-centered lifestyle intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Help-Seeking Behavior, Help-seeking Intention
Antenatal Depression Help-seeking Trial in Eswatini
The goal of this trial to test if a web-based psychoeducation will work in improving depression help-seeking intention and behavior among antenatal women with probable depression in Eswatini.
- Conditions
- Help-Seeking Behavior, Help-seeking Intention, Antenatal Depression
- Trial name
- ADHS-RCT (NCT06390735)
- Testing
- Mommy ReachOut Intervention
- Where
- 2 sites in Eswatini
- Volunteers
- 214 people
- Sponsor
- Taipei Medical University
Recruitment of Minorities
A Randomized Recruitment Intervention Trial
The purpose of this study is to test a recruitment intervention to increase racial and ethnic diversity in clinical trials. The trial will be conducted in specialty care clinics.
- Trial name
- RECRUIT (NCT01911208)
- Testing
- RECRUIT intervention, Control
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Behaviour
The Dietary Intervention in e-Shopping Trial
The supermarket industry now services many customers through online food shopping over the Internet. The Internet shopping process offers a novel opportunity for the modification of dietary patterns.
- Trial name
- NCT00352508
- Testing
- Dietary advice
- Where
- Australia
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- The George Institute
Paralytic Lagophthalmos, Leprosy--Patients
Modified Tarsorrhaphy vs Gold Weight Implant for Paralytic Lagophthalmos in Leprosy Patients
This study aims to compare the effectivity and efficiency of Modified Tarsorrhaphy (MT) technique and Gold Weight Implant (GWI) technique as a surgical treatment of paralytic lagophthalmos in leprosy patients.
- Trial name
- NCT04944498
- Testing
- Modified Tarsorrhaphy, Gold Weight Implant
- Where
- 3 sites in Indonesia
- Volunteers
- 19 people
- Sponsor
- Yunia Irawati
Depression
Effectiveness of Internet-Based Cognitive Behavioral Therapy for Treating Mothers With Depression
This study will evaluate the effectiveness of an Internet-based cognitive behavioral therapy program in treating mothers with depression who have young children.
- Trial name
- NCT00601393
- Testing
- Cognitive behavioral therapy (CBT), Treatment as usual (TAU)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Oregon Research Institute
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