Clinical trials: Interventions
Haemodialysis Patients, Laughter Yoga
Laughter Yoga Intervention in Patients on Haemodialysis
This study was planned as a randomized controlled experimental type and pre-test-post-test design in order to examine the effects of laughter yoga applied to hemodialysis patients on the happiness and mental well-being levels of…
- Trial name
- laughter yoga (NCT06938737)
- Testing
- laughter yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Muğla Sıtkı Koçman University
Enrichment With Meaning-generating Activities, Rehabilitation as Usual
Enrichment of Day Centers in Community-based Psychiatry
This RCT study addresses the topic of improving the possibilities for people with severe mental illness (SMI) to be engaged in meaningful daily occupations at community-based activity (CBA) centers.
- Trial name
- NCT01732575
- Testing
- Enrichment with meaning-generating activities
- Volunteers
- 107 people
- Sponsor
- Lund University
Frailty, Malnutrition
Frail2Fit Study: Online Nutrition and Exercise Support for Older Adults With Frailty
Frail2Fit will explore the feasibility of training volunteers to deliver online nutrition, exercise, and behaviour change (supported self-management) to improve the health of older people after discharge from hospital.
- Conditions
- Frailty, Malnutrition, Sedentary Behavior
- Trial name
- NCT05384730
- Testing
- Group nutrition and exercise support
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
AMI
Effect of Lantus and Apidra in Patients With Acute ST Elevation Myocardial Infarction
Primary objective: To demonstrate that in hyperglycemic subjects with anterior STEMI (ST Elevation Myocardial Infarction) undergoing Percutaneous Coronary Intervention (PCI), tight glycemic control using insulin glulisine and…
- Trial name
- INTENSIVE (NCT00670228)
- Testing
- Insulin Glargine (LANTUS), Insulin Glulisine (Apidra), Standard Therapy
- Where
- 5 sites in United States, Argentina and 3 more
- Volunteers
- 34 people
- Sponsor
- Sanofi
Cerebral Palsy
Implementation of a New Motor Skill Learning Therapeutic Device in Children With Cerebral Palsy Rehabilitation
Study of the efficiency of a new interactive interface to apply all the therapeutic principles of motor skill learning used in high dosage intensive interventions.
- Trial name
- NCT03930836
- Testing
- Hand Arm Bimanual Intensive Therapy Including Lower Extremities, Conventional physical and occupational therapy
- Where
- Belgium
- Volunteers
- 64 people
- Sponsor
- Université Catholique de Louvain
Osteo Arthritis Knee and Hip
Effect of Exercise on Muscle Activity, Strength, and Balance in People With Knee Osteoarthritis
This will be a clinical trial of a standardized group exercise intervention, Les Mills Thrive, and determine if it alters muscle activation patterns and improves strength, balance, and symptoms in those with knee osteoarthritis…
- Trial name
- NCT07073911
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- Gillian Hatfield
Atopic Dermatitis, Atopic
Dietary Intervention on Atopy
Diet is a key determinant of overall health, with growing evidence associating dietary patterns with allergic diseases. Among these, atopic dermatitis (AD) is of particular interest as it often represents the earliest…
- Conditions
- Atopic Dermatitis, Atopic, Allergic Diseases, Allergic Rhinitis
- Trial name
- NCT06547372
- Testing
- Dietary Intervention on Atopy
- Where
- Singapore
- Volunteers
- 110 people
- Sponsor
- National University of Singapore
Chronic Pain, Alcohol Use, Unspecified
St. PETERsburg Pain and Alcohol Intervention With Naltrexone and Gabapentin
This study is a 3-arm pilot, randomized, double-blinded, placebo-controlled study of low-dose naltrexone and gabapentin versus placebo among HIV-positive persons with heavy alcohol use and chronic pain to provide estimates of…
- Conditions
- Chronic Pain, Alcohol Use, Unspecified, HIV Infections
- Trial name
- UH3 (NCT04052139)
- Testing
- Low-dose naltrexone, Gabapentin
- Where
- Russia
- Volunteers
- 45 people
- Sponsor
- Boston Medical Center
Benzodiazepines Therapeutic Use
Implementation Strategies for a Simple Intervention to Reduce Longterm Benzodiazepine Use in Dutch Community Pharmacies
The purpose of this study is to compare the effect of two implementation strategies for a simple patient-directed intervention to reduce long-term benzodiazepine use in Dutch community pharmacies.
- Trial name
- NCT00268775
- Testing
- training and follow-up of pharmacists, patient-directed discontinuation letter
- Where
- 90 sites in Netherlands
- Volunteers
- 20,000 people
- Sponsor
- Radboud University Medical Center
Caregivers of Multi-pathological and Polypharmacy Adults
Safe Use of Medication at Home by Caregivers. Experimental Study
Experimental study to test the effectiveness of a psychoeducational intervention using virtual reality, aimed at caregivers of multi-pathological and polypharmacy persons to promote safer medication use at home.
- Trial name
- NCT05247801
- Testing
- Psychoeducational intervention for safe medication use at home + Medication dosing device, Medication dosing device
- Where
- Spain
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Universidad Miguel Hernandez de Elche
Hypoxemia
Capnography Monitoring During Intravenous Conscious Sedation Sedation With Midazolam for Oral Surgery
Dentists use sedation to help patients accept difficult procedures and to relieve anxiety. During sedation, the well-being of the patient is monitored by the dental team.
- Trial name
- NCT01949012
- Testing
- Capnography
- Where
- Ireland
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- University College Cork
Crohn Disease
A Study on the Impact of Online Positive Psychological Intervention on the Mental Health and Quality of Life of Crohn's Disease Patients
Crohn's disease (CD) is a chronic, nonspecific inflammatory disease that can affect the entire digestive tract. It is difficult to cure and often relapses, causing long-term suffering for patients.
- Trial name
- NCT06939712
- Testing
- Online Positive Psychology Intervention, Routine Care
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Parenting, Parent-Child Relations
Parenting Young Children in Pediatrics
In this study, investigators will partner with pediatric primary care providers to recruit parent participants, then evaluate feasibility and acceptability by systematically assessing parents' engagement with the FCU Online app.
- Conditions
- Parenting, Parent-Child Relations, Substance Use Disorders, Stress
- Trial name
- NCT06273228
- Testing
- Family Check-Up Online
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Oregon
Diet Modification
Effects of Calcium Supplementation on Women in the Curves for Women Program
The purpose of this study is to examine the effects of dietary calcium supplementation on weight loss, bone density, and markers of health and fitness in women participating in the Curves exercise and diet program.
- Trial name
- NCT03878667
- Testing
- Curves Calcium, Calcium Carbonate
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
ST-segment Elevation Myocardial Infarction
Phase 2 Study to Evaluate the Efficacy, Safety and PK of Intravenous Single Injection LC28-0126 Immediately Before PCI in STEMI Patients
Evaluate the efficacy, Safety and Pharmacokinetics of Intravenous single injection LC28-0126 immediately before PCI (Percutaneous Coronary Intervention) in Patients with STEMI (ST-segment Elevation Myocardial Infarction)
- Trial name
- NCT02070471
- Testing
- LC28-0126 Dose A, LC28-0126 Dose B, LC28-0126 Dose C
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- LG Life Sciences
Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI), High Bleeding Risk
Genotype-Guided Abbreviated DAPT Versus Un-Guided De-escalation Therapy in Patients With ACS and HBR
The aim of this study is to assess the safety and efficacy of the CYP2C19 genotype-guided abbreviated dual antiplatelet therapy (DAPT) strategy versus the un-guided stepwise intensity de-escalation of DAPT strategy in patients…
- Trial name
- GUIDE-HBR (NCT06763744)
- Testing
- P2Y12 antagonist monotherapy, clopidogrel + aspirin
- Where
- South Korea
- Volunteers
- 3,000 people
- Sponsor
- Samsung Medical Center
Cervical Cancer Screening, Breast Cancer Screening
Social Media-Based Education on Cancer Screening Awareness in Women: A Randomized Controlled Trial
This randomized controlled study evaluated a social media-based educational program for women who had not previously participated in breast, cervical, or colorectal cancer screening.
- Conditions
- Cervical Cancer Screening, Breast Cancer Screening, Colorectal Cancer Screening, Digital Health Literacy
- Trial name
- NCT06939699
- Testing
- Social Media-Based Education, Standard Online Education
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Emine Ergin
Usher Syndrome Type 3
BF844 Safety and Pharmacokinetic Study in Healthy Volunteers
First-in-Human Phase-1 Clinical Trial to Assess Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Food Effect of Single and Multiple Ascending Doses of BF844 when Administered Orally to Healthy Adult Participants.
- Trial name
- NCT06592131
- Testing
- BF844
- Where
- Australia
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- EyeXCel Pty. Ltd.
Weight Loss, Pediatric Obesity
Dyad Plus Effectiveness/Feasibility
The purpose of this research is to determine the effectiveness of a coordinated program (Dyad Plus) that would help to facilitate self-monitoring, positive communication, joint problem solving, and social support to increase…
- Conditions
- Weight Loss, Pediatric Obesity, Overweight Adolescents, Parent-Child Relations
- Trial name
- NCT04036331
- Testing
- Brenner FIT Standard, By Design Essentials, Dyad Plus
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Wake Forest University Health Sciences
Dementia (Diagnosis)
DemTool - Supporting Life With Dementia
This study will investigate the effects of a Danish psychosocial intervention, specifically the DemTool - supporting life with dementia, on quality of life and caregiver strain in family caregivers of people with dementia.
- Trial name
- DemTool (NCT07355829)
- Testing
- Life with dementia in the community - Support group for family caregivers, Life with dementia in the community - Group course, Life with dementia in a care home- Group course
- Where
- Denmark
- Volunteers
- 272 people
- Sponsor
- Danish Dementia Research Centre
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