Clinical trials: Intervertebral Disc Disorder
Disc Herniation
The Effect of White Noise in Patients Undergoing Lumbar Disc Herniation Surgery
The aim of this clinical trial is to determine the effectiveness of listening to white noise on the sleep quality, comfort level, satisfaction level of patients after lumbar disc herniation surgery.
- Trial name
- NCT05687305
- Testing
- White Noise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Radiculopathy, Cervical, Myelopathy Cervical
Cervical Arthroplasty Cost Effectiveness Study (CACES)
To date, no consensus exists on which anterior surgical technique is more cost-effective to treat cervical degenerative disc disease (CDDD).
- Conditions
- Radiculopathy, Cervical, Myelopathy Cervical, Myelopathy, Compressive, Radiculopathy, Cervical Region
- Trial name
- CACES (NCT04623593)
- Testing
- ACDF, ACDA
- Where
- Netherlands
- Volunteers
- 198 people
- Sponsor
- Valérie Schuermans
Sciatica, Sciatica Due to Intervertebral Disc Disorder
Transforaminal Epidural Injection in Acute Sciatica
Patients suffering from sciatica are treated conservatively for the first 8 weeks due to the favourable prognosis. This period is preferably extended up to 14-16 weeks after which patients may opt for surgery.
- Conditions
- Sciatica, Sciatica Due to Intervertebral Disc Disorder, Sciatic Radiculopathy
- Trial name
- TEIAS (NCT03924791)
- Testing
- Lidocaine, Methylprednisolone Acetate, Dexamethasone
- Where
- 2 sites in Netherlands
- Volunteers
- 142 people
- Sponsor
- C.L.A.Vleggeert-Lankamp
Intervertebral Disc Displacement, Lumbar Disc Herniation
The Effect of Manual Therapy on Psychological Factors and Quality of Life in Lumbal Disc Herniation Patients
When the literature is examined, there are studies examining the relationship between low back pain and anxiety depression, quality of life and LDH in patients with lumbar disc herniation.
- Conditions
- Intervertebral Disc Displacement, Lumbar Disc Herniation, Psychological, Quality of Life
- Trial name
- NCT05804357
- Testing
- Manual Therapy, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Muş Alparslan University
Intervertebral Disc Disorders With Radiculopathy, Lumbar Region
The Effects of Perioperative Nutritional Optimization on Blood Markers
The purpose of this study is to see if taking an oral nutrition supplement (Ensure Nutrition Shake) before and after lumbar spine surgery affects blood tests related the nutritional status of patients.
- Trial name
- NCT04464161
- Testing
- Ensure
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- NYU Langone Health
Intervertebral Disc Disorder Lumbar With Radiculopathy, Surgical or Other Invasive Procedure on Wrong Patient
Directed Imagery Technique Applied to Patients Undergoing Lumbar Disc Herniation Surgery
The Directed Imagery technique (YIT) is a set of stories that people create by first giving relaxation exercises and then visualizing the symbols given by the practitioner.
- Conditions
- Intervertebral Disc Disorder Lumbar With Radiculopathy, Surgical or Other Invasive Procedure on Wrong Patient, Nurse-Patient Relations
- Trial name
- NCT05283291
- Testing
- Directed Imagery Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Intervertebral Disc Disorder, Thoracic Intervertebral Disc Disorders
Spine Surgery for Adhesions in Patients Evaluated for Efficacy and Safety of MedicurtainⓇ (Pivotal Study)
This study was designed to evaluate the efficacy and safety of Medicurtain®, an antiadhesion barrier in patients who underwent In Situ Decompression for single level and unilateral herniated lumbar intervertebral disc.
- Conditions
- Intervertebral Disc Disorder, Thoracic Intervertebral Disc Disorders, Thoracolumbar Intervertebral Disc Disorders, Lumbosacral Intervertebral Disc Disorders
- Trial name
- NCT04688281
- Testing
- Medicurtain®, GUARDIX-SG®
- Where
- South Korea
- Volunteers
- 87 people
- Sponsor
- Shin Poong Pharmaceutical Co. Ltd.
Low Back Pain, Disc Disease
Bone Marrow Concentrate (BMC) Injection in Intervertebral Discs
Intradiscal delivery of bone marrow concentrate (BMC) into discs, facet, epidural space, and sacroiliac joints
- Conditions
- Low Back Pain, Disc Disease, Disc Degeneration, Arthropathy Vertebrae
- Trial name
- NCT04559295
- Testing
- Bone Marrow Concentrate
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Stem Cures
Sciatica Due to Intervertebral Disc Disorder, Intervertebral Disc Displacement
Observational Study on Effectiveness and Safety of Integrative Korean Medicine Treatment for Inpatients With Sciatica Due to Lumbar Intervertebral Disc Herniation
Observational study on the effectiveness and safety of integrative Korean medicine treatment for inpatients with sciatica due to lumbar intervertebral disc herniation
- Conditions
- Sciatica Due to Intervertebral Disc Disorder, Intervertebral Disc Displacement, Sciatica, Sciatic Radiculopathy
- Trial name
- NCT03750591
- Testing
- Herbal medicine, Chuna manual therapy, Bee venom pharmacopuncture
- Where
- 4 sites in South Korea
- Volunteers
- 1,000 people
- Sponsor
- Jaseng Medical Foundation
Intervertebral Disc Disorder Cervical
Triadyme-C, a Polycrystalline Diamond Compact Cervical Disc Replacement (cTDR)
This Post Market Clinical Follow-up (PMCF) is conducted to collect clinical and radiographic outcome information on patients suffering from intractable symptomatic cervical disc disease requiring 1- or 2-level reconstruction of…
- Trial name
- NCT02967575
- Testing
- cTDR
- Where
- 4 sites in Germany
- Volunteers
- 100 people
- Sponsor
- Dymicron
Sciatica, Intervertebral Disc Disorder
Alternative and Integrative Therapy for Lumbar Disk Herniation
The investigators report management of lumbar disc herniation with severe sciatic pain using an integrative complementary and alternative medicine approach with a 5 year follow-up.
- Trial name
- NCT01989403
- Testing
- herbal medicine, acupuncture, bee-venom acupuncture, and Chuna manipulation
- Where
- South Korea
- Volunteers
- 128 people
- Sponsor
- Jaseng Hospital of Korean Medicine
Chronic Low Back Pain, Degenerative Disc Disease
Opioid Treatment for Chronic Low Back Pain and the Impact of Mood Symptoms
Opioids are frequently prescribed for chronic low back pain (CLBP). Psychiatric illness, such as high levels of depression and anxiety symptoms, is a common co-occurrence in chronic pain patients (and is termed comorbid negative…
- Conditions
- Chronic Low Back Pain, Degenerative Disc Disease, Depression, Anxiety
- Trial name
- NCT01502644
- Testing
- Oxycodone, Morphine
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Brigham and Women's Hospital
Disease (or Disorder); Intervertebral Disc, With Myelopathy (Manifestation)
NORSPAN Transdermal Patches Phase III Study In Non-Cancer Pain
This is a multiple-dose, double-blind, double-dummy, active-control, parallel-group, multi-center, safety and efficacy study.
- Trial name
- NCT01476774
- Testing
- Buprenorphine Transdermal System
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Mundipharma (China) Pharmaceutical Co. Ltd
Sciatica Due to Intervertebral Disc Disorder
Electroacupuncture for Sciatica Due to Intervertebral Disc Displacement
This multicenter randomized controlled trial (RCT) will evaluate the therapeutic effectiveness and health-economics of electroacupuncture for sciatica due to intervertebral disc displacement in 3 compared groups…
- Trial name
- NCT02087462
- Testing
- Electroacupuncture (EA), Traction, Voltaren
- Where
- China
- Volunteers
- 324 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Lumbar and Other Intervertebral Disc Disorders With Radiculopathy
Epidural Clonidine for Lumbosacral Radiculopathy
This was a randomized, blinded study of transforaminal epidural injection of clonidine versus a similar injection of corticosteroid for acute lumbosacral radiculopathy.
- Trial name
- NCT00588354
- Testing
- Clonidine, Triamcinolone hexacetonide, Lidocaine HCl
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Herniated Disk, Temporomandibular Disorders
Randomized Clinical Trial of Treatment for Temporomandibular Joint (TMJ) Disc Displacement
The effectiveness of physical therapy for treatment of anterior disc displacement without reduction of temporomandibular disorders has not been well defined.
- Trial name
- NCT00936338
- Testing
- splint and joint mobilization self exercise
- Where
- Japan
- Volunteers
- 44 people
- Sponsor
- Tokyo Medical and Dental University