Clinical trials: Intestinal Edema
Intraoperative Fluid Volume, Hemodynamics
Pulse Pressure Variation Based Intraoperative Fluid Management Versus Traditional Fluid Management for Colonic Cancer Patients Undergoing Mass Resection and Anastomosis
pulse pressure variation based intraoperative fluid therapy versus traditional fluid therapy for colonic cancer patients undergoing mass resection and anastomosis for maintaining adequate hydration without complications.
- Conditions
- Intraoperative Fluid Volume, Hemodynamics, Serum Lactate, Intestinal Edema
- Trial name
- NCT05502835
- Testing
- pulse pressure variation, conventional fluid management
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Diverticulitis
Italian Study Group on Complicated Diverticulosis
Patients were recruited over a four year period from 1996 to 1999. Those admitted in the years 1996 and 1997 were retrospectively accrued from the clinical records, while patients treated between 1998 and 1999 patients were…
- Trial name
- GISDIC (NCT01276886)
- Testing
- antibiotic, Colonic resection with or without stoma
- Where
- Italy
- Sponsor
- Gruppo Italiano per lo Studio della Diverticolite Complicata
Surgery-Complications, Overload Fluid
Prediction of Complications After Major Gastrointestinal Surgery With Machine Learning and Point of Care Ultrasound
This is an observational study in patients undergoing major surgery. In which we attempt to predict complications (e.g. low blood pressure, ICU-admittance after major surgery using continuous blood pressure measurements.
- Trial name
- AI_PLUS (NCT06166719)
- Testing
- No intervention
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Hemorrhoids, Postoperative Pain
Ice Packing Versus Warm Sitz Baths After Hemorrhoidectomy
Warm sitz baths are commonly recommended after hemorrhoidectomy, although their benefit for early postoperative recovery remains uncertain. Local cold application may reduce postoperative pain and perianal swelling.
- Trial name
- NCT07843563
- Testing
- Cryotherapy (Ice Packing), Warm Sitz Bath
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people
- Sponsor
- Memorial Atasehir Hospital
Severe Acute Malnutrition
Ready to Use Therapeutic Food (RUTF) in Severe Malnourished Children
1. RUTF would be more effective (quicker catch-up growth by promoting more tissue accrue resulting decrease stay in rehabilitation ward) in treating children with SAM during the rehabilitation phase than khichuri /halwa; 2.
- Trial name
- RUTF (NCT01331044)
- Testing
- Plumpy Nut, Khichuri and Halwa
- Where
- Bangladesh
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Intestinal Obstruction, Intestinal Perforation
Pathophysiology of Perioperative Fluid Management in Emergency Laparotomy
Pathophysiology of perioperative fluid management in patients undergoing emergency laparotomy.
- Conditions
- Intestinal Obstruction, Intestinal Perforation, Anastomotic Leak, Fluid Overload
- Trial name
- NCT03997721
- Where
- Denmark
- Volunteers
- 73 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Acute Respiratory Distress Syndrome, Coronavirus
Pemziviptadil (PB1046), a Long-acting, Sustained Release Human VIP Analogue, Intended to Provide Clinical Improvement to Hospitalized COVID-19 Patients at High Risk for Rapid Clinical Deterioration and Acute Respiratory Distress Syndrome (ARDS).
This is a multicenter, randomized, double-blind, parallel group study to investigate the efficacy of pemziviptadil (PB1046) by improving the clinical outcomes in hospitalized COVID-19 patients at high risk for rapid clinical…
- Conditions
- Acute Respiratory Distress Syndrome, Coronavirus, Hypoxic Respiratory Failure, Hypoxemic Respiratory Failure
- Trial name
- VANGARD (NCT04433546)
- Testing
- Pemziviptadil (PB1046), Low Dose (10 mg) Control
- Where
- 4 sites in United States
- Volunteers
- 54 people
- Sponsor
- PhaseBio Pharmaceuticals Inc.
Rectal Neoplasm Malignant
Latitude - Lateral Lymph Node Attitude Study
Patients with advanced rectal cancer can sometimes have suspected tumour affected lymph nodes outside the standard operating field. These patients often receive preoperative treatment before surgery.
- Trial name
- Latitude (NCT06896578)
- Testing
- Lateral lymph node dissection
- Where
- Sweden
- Volunteers
- 1,000 people
- Sponsor
- Sahlgrenska University Hospital