Clinical trials: Intestinal Fistula
Pancreatic Cancer, Periampullary Cancer
Tissue Adhesive Glue Modified Cyanoacrylate (Glubran® 2) in Soft Pancreas
This is a single-center, randomized controlled trial comparing the efficacy of pancreaticojejunostomy with modified N-butyl-2-cyanoacrylate(Glubran® 2) versus standard pancreaticojejunostomy without cyanoacrylate in preventing…
- Conditions
- Pancreatic Cancer, Periampullary Cancer, Duodenal Cancer, Cholangiocarcinoma
- Trial name
- NBCA-MS (NCT07155525)
- Testing
- Pancreaticojejunostomy with Modified N-Butyl-2-Cyanoacrylate (Glubran® 2), Standard(duct-to-mucosa) Pancreaticojejunostomy
- Where
- Egypt
- Volunteers
- 194 people
- Sponsor
- Minia University
Fistula in Ano
PRP Use in Treatment of Fistula Ano
In treatment of perianal fistula several methods are described. However, since the Hippocrates basics of surgical treatment has not changed very much.
- Trial name
- NCT04187651
- Testing
- platelet rich plasma
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Uşak University
Anal Fistula
Adipose Tissue Injection for the Treatment of Complex Cryptoglandular Perianal Fistula
The incidence of complex cryptoglandular anal fistula is high, it affects eminently young patients and implies an important alteration in their quality of life and high prevalence in sick leave.
- Trial name
- AdiTiF (NCT04790123)
- Testing
- Injection of autologous freshly collected adipose tissue
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital Mutua de Terrassa
Rectal Fistulas
FISTULA-RFA Trial: Radiofrequency Ablation for Perianal Fistula
The goal of this pilot clinical study is to learn whether radiofrequency ablation (RFA) can safely and effectively treat perianal fistulas in adults.
- Trial name
- FISTULA-RFA (NCT07452666)
- Testing
- Radiofrequency Ablation (RFA) for Perianal Fistula
- Volunteers
- 80 people
- Sponsor
- Korea University Ansan Hospital
Hemorrhoid, Peri Anal Fistula
Discharge Conditions of Spinal Anesthesia With Heavy Prilocaine-Fentanyl and Heavy Bupivacaine-Fentanyl
In this prospective randomized study the investigators aimed to investigate difference of the duration of spinal anesthesia, discharge times and efficacy between low dose heavy Prilocaine-Fentanyl and heavy Bupivacaine-Fentanyl…
- Trial name
- NCT01880775
- Testing
- Prilocaine, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Diskapi Teaching and Research Hospital
High Perianal Fistula
Comparative Study: Fistula Rerouting vs. LIFT for High Perianal Fistula
The goal of this clinical trial is to compare two different surgery methods for treating a complex type of anal fistula. This condition is an abnormal tunnel connecting the inside of the anus to the skin nearby.
- Trial name
- NCT07399353
- Testing
- Fistula Rerouting Technique, Ligation of Intersphincteric Fistula Tract
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Fistula in Ano
Fistulotomy With Marsupialization Versus Fistulectomy With Wound Sutures in Simple Anal Fistula
comparison between fistulectomy wound closure and fistulotomw wound marsupialization in treatment of simple anal fistula
- Trial name
- NCT04215718
- Testing
- fistulotomy and marsupialization, fistulectomy and wound closure
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Zagazig University
Perianal Fistula, Crohn Disease
Fistulodesis Pilot Study for Closure of Perianal Fistulae
In this pilot study a new surgical treatment approach for perianal fistulae, called Fistulodesis, is performed. The study aims to assess effectiveness, safety and tolerability of the Fistulodesis procedure.
- Trial name
- NCT03322488
- Testing
- Fistulodesis
- Where
- 2 sites in Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Hemorrhoid, Anal Fistulas
Effect of Listening to Standardized Music Sequences on Preventing Postoperative Pain in Proctologic Surgery
The study, "Effect of Listening to Standardized Music Sequences on Preventing Postoperative Pain in Proctologic Surgery," aims to evaluate the impact of preoperative listening to standardized music sequences on postoperative pain…
- Conditions
- Hemorrhoid, Anal Fistulas, MUSICAL THERAPY, Anal Fissure and Fistula
- Trial name
- MUSICOPROCTO (NCT06798155)
- Testing
- Standardized Music Listening Therapy
- Where
- 2 sites in Reunion
- Volunteers
- 550 people
- Sponsor
- Clinique Saint-Vincent
Anal Fistula, Perianal Fistula
Comparison Of Surgical Outcomes Between Ligation Of Intersphincteric Fistula Tract And Fistulotomy With Seton In Perianal Fistula
This study aims to compare two commonly used surgical techniques for the treatment of perianal fistula: Ligation of the Intersphincteric Fistula Tract (LIFT) and fistulotomy with seton.
- Conditions
- Anal Fistula, Perianal Fistula, Fistula-in-ano
- Trial name
- LIFT-SETON (NCT07579715)
- Testing
- Ligation of Intersphincteric Fistula Tract (LIFT), Fistulotomy with Seton Placement
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Islamabad Medical and Dental College
Crohn's Disease
A Study of TH-SC01 for Treating Complex Perianal Fistula in Perianal Crohn's Disease.
The purpose of this study is to asses the efficacy and Safety of Allogeneic Umbilical Cord-derived Mesenchymal Stem Cells in the Treatment of Complex Perianal Fistula in Perianal Crohn's Disease.
- Trial name
- NCT04939337
- Testing
- TH-SC01
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Jinling Hospital, China
Anorectal Fistula
Retrospective Review of the Cook Biodesign® Fistula Plug to Treat Anorectal Fistulas
The study is a retrospective review of the use of the Biodesign® Fistula Plug (C-FPS-[X]). A total of 73 patients will be enrolled who have had a fistula plug placed to treat anorectal fistulas and will therefore be eligible for…
- Trial name
- NCT03321266
- Testing
- Cook Biodesign® Fistula Plug
- Where
- 4 sites in United States, Germany
- Volunteers
- 79 people
- Sponsor
- Cook Group Incorporated
Complex Perianal Fistula, Crohn Disease
Safety and Efficacy of Adipose-Derived Stem Cells to Treat Complex Perianal Fistulas Patients With Crohn's Disease
The purpose of this study is to determine safety and efficacy of eASCs (expanded adult stem cells) for treatment of complex perianal fistulas in patients with Crohn's disease.
- Trial name
- FATT (NCT01378390)
- Testing
- Expanded autologous adipose-derived adult stem cells (eASCs)
- Where
- 12 sites in Austria, Netherlands and 1 more
- Volunteers
- 56 people
- Sponsor
- Tigenix S.A.U.
Crohn's Disease
Exclusive Enteral Nutrition Therapy for Active and Complicated Crohn's Disease
The goal of this observational study is to evaluate the effectiveness and safety of exclusive enteral nutrition (EEN) in adults with active Crohn's disease (CD), particularly in patients with complicated disease such as…
- Trial name
- EEN-CD (NCT07504510)
- Testing
- Exclusive Enteral Nutrition
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Crohn Disease
Self Screening Tool for Crohn's Perianal Fistula
This study aims to develop a self-screening tool for Crohn's perianal fistula.
- Trial name
- NCT03288961
- Where
- South Korea
- Volunteers
- 146 people
- Sponsor
- Kyungpook National University Hospital
High Perianal Fistula, Fistula-in-Ano
Seton Re-routing for High Perianal Fistula
High perianal fistulae involve a significant portion of the external anal sphincter muscle, making standard surgical fistulotomy risky due to the potential for postoperative fecal incontinence.
- Conditions
- High Perianal Fistula, Fistula-in-Ano, High Anal Fistula
- Trial name
- NCT07850440
- Testing
- Seton Re-routing
- Volunteers
- 35 people
- Sponsor
- Assiut University
Anal Fistula
BIOlogic Augmented Repair of Complex Anal Fistula Using Acellular Matrix and/or Autologous Platelet-rich Plasma
The purpose of this study is to compare the clinical effectiveness of augmenting surgical repair of complex anal fistula using autologous PRP and/or micronized acellular porcine urinary bladder matrix (UBM) to usual surgical care…
- Trial name
- BIO RAMP (NCT05805449)
- Testing
- Surgery, Platelet-rich plasma (PRP), Matrix
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- The University of Texas Health Science Center, Houston
Fistula in Ano
Two Approaches to Lower the Chances of Recurrence of Anal Fistula After Surgery
A total of 80 patients with complex fistula in ano of both genders were included. All patients in Group A underwent a loose seton technique.
- Trial name
- NCT06380036
- Testing
- video assisted fistula tract surgery
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sairah Sadaf
Crohn's Disease
A Survey of Darvadstrocel in People With Crohn's Disease
This study is a survey in Japan of Darvadstrocel injection used to treat Crohn's disease people with complicated anal fistula. The study sponsor will not be involved in how the participants are treated but will provide…
- Trial name
- J-INSPIRE (NCT05113095)
- Testing
- Darvadstrocel
- Where
- Japan
- Volunteers
- 275 people
- Sponsor
- Takeda
Perianal Fistula, Crohn's Disease
Study of ExoFlo for the Treatment of Perianal Fistulas
To evaluate the safety and feasibility of ExoFlo as a treatment for Perianal Fistulizing Crohn's Disease.
- Trial name
- NCT05836883
- Testing
- ExoFlo, Local injection of normal saline
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Direct Biologics, LLC