Clinical trials: Intestinal Manipulation
Segmental and Somatic Dysfunction, Pathological Conditions, Signs and Symptoms
Correlation of Somatic Dysfunction With Gastrointestinal Endoscopic Findings
The purpose of this study is to correlate the link between palpatory findings of somatic dysfunction and gastrointestinal endoscopic evidence of changes in mucosa.
- Conditions
- Segmental and Somatic Dysfunction, Pathological Conditions, Signs and Symptoms, Ectopic Intestinal Mucosa
- Trial name
- NCT01394198
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- A.T. Still University of Health Sciences
Irritable Bowel Syndrome
Manipulation of Visceral Hypersensitivity With Probiotic Bacteria in Irritable Bowel Syndrome
Irritable bowel syndrome is a common digestive disorder worldwide. However, there is no effective treatment of irritable bowel syndrome.
- Trial name
- NCT01139736
- Testing
- VSL#3
- Where
- Hong Kong
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Enteritis, Bleeding
Balloon-assisted Enteroscopy and Bacteria
1. Balloon-assisted enteroscopy (BAE) is a new tool to investigate small intestinal diseases. 2. Deep enteroscopy made possible by balloon expansion and manipulation of small intestines. 3.
- Trial name
- NCT01065324
- Where
- 2 sites in Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Irritable Bowel Syndrome
Manipulation of Visceral Sensitivity and Immune System in IBS
Irritable bowel syndrome (IBS) is a common condition. At least 20% of the population suffer from IBS. The symptoms of abdominal pain, diarrhoea, constipation, bloating and difficulty with bowel motions are often disabling.
- Trial name
- NCT00418340
- Testing
- probiotic (bacterial/dietary supplement)
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- London North West Healthcare NHS Trust
Spinal Cord Injuries
Osteopathic Manipulative Treatments and Neurogenic Bowel Dysfunction in Patients With Spinal Cord Injuries.
Studies based on the relationship between Osteopathic Manipulative Treatment (OMT) and the gastrointestinal system have been conducted in patients with constipation with Irritable Bowel Syndrome (IBS), and in children with…
- Trial name
- NCT04367571
- Testing
- Osteopathic Manipulative treatment (OMT)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Intestinal Pseudo-Obstruction, Manipulation, Osteopathic
Rib Raising for Post-operative Ileus
We are conducting a randomized controlled trial the use of rib raising for post-operative ileus. Rib raising is an osteopathic manipulative technique (OMT).
- Conditions
- Intestinal Pseudo-Obstruction, Manipulation, Osteopathic, Postoperative Care, Postoperative Nausea and Vomiting
- Trial name
- NCT03662672
- Testing
- Rib raising and lumbar release
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Rutgers, The State University of New Jersey
Ulcerative Colitis
A Study to Evaluate the Effect of Fecal Transplant and Dietary Changes on Disease Activity in Patients With Ulcerative Colitis on Advanced Therapies
Ulcerative colitis (UC) is a chronic inflammatory disease of the colon characterized by superficial mucosal inflammation. Treatment aims to achieve and maintain remission, improve quality of life, and minimize complications.
- Trial name
- BOOST-UC (NCT06906445)
- Testing
- Fecal Microbial Transplantation, Anti-Inflammatory Diet, Advanced Therapy
- Where
- 6 sites in India
- Volunteers
- 220 people
- Sponsor
- All India Institute of Medical Sciences
Ulcerative Colitis (UC)
A Study to Evaluate the Effect of Fecal Transplant and Dietary Changes on Disease Activity in Patients With Newly Diagnosed Active Ulcerative Colitis
Ulcerative colitis (UC) is a chronic inflammatory condition affecting the colon and rectum, characterized by mucosal inflammation and symptomslike diarrhea, abdominal pain, and rectal bleeding.
- Trial name
- ALTER-UC (NCT06895252)
- Testing
- Anti inflammatory diet, Fecal Microbial Transplantation
- Where
- 6 sites in India
- Volunteers
- 220 people
- Sponsor
- All India Institute of Medical Sciences
Rectal Cancer, Colorectal Cancer
Body Composition Manipulation in CoLorectal cancEr (BiCyCLE): Neuromuscular Electrical Stimulation (NMES)
Muscle is lost as part of the rectal cancer disease process. Surgery to treat rectal cancer and its subsequent immobility leads to increased muscle loss.
- Conditions
- Rectal Cancer, Colorectal Cancer, Colon Cancer, Colo-rectal Cancer
- Trial name
- BiCyCLE-NMES (NCT04065984)
- Testing
- Microstim 2v2 Stimulator
- Where
- United Kingdom
- Volunteers
- 46 people
- Sponsor
- London North West Healthcare NHS Trust
Colorectal Cancer
Manipulation of the Gut Microbiome by a Standardized Preoperative Diet to Prevent Colorectal Cancer Recurrence and Metastasis Following Surgery
A single arm, prospective, single center Phase1/2 Dietary intervention trial for subjects diagnosed with colorectal cancer and scheduled for tumor resection more than 21 days from informed consent.
- Trial name
- DIET (NCT06349590)
- Testing
- High-fiber/low-fat meals
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Chicago
Intestinal Manipulation
Study on the Effect of Surgical Intestinal Manipulation
The aim of this study is to study the impact of brain death and surgical small bowel manipulation on the release of different types of monocytes.
- Trial name
- IMMO (NCT02189512)
- Testing
- blood sampling
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Colorectal Cancer, Surgery
Microbiota Implementation to Reduce Anastomotic Colorectal Leaks (MIRACLe)
Aim of this study is to implement the intestinal microbiota by perioperative administration of probiotics, oral antibiotics and low volume mechanical preparation in order to reduce the incidence of colorectal anastomotic leaks…
- Conditions
- Colorectal Cancer, Surgery, LAP, Anastomotic Leak
- Trial name
- MIRACLe (NCT05164887)
- Testing
- Laparoscopic colorectal resection
- Where
- Italy
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- S.Eugenio Hospital
Central Nervous System Injury, Neurogenic Bowel Dysfunction
Effects of Osteopathic Manipulative Treatment in People With Neurogenic Bowel Dysfunction
People affected central nervous system (CNS) diseases often suffer from neurogenic bowel dysfunction (NBD) that causes a reduction in the quality of life and participation in social life.
- Trial name
- NCT04127617
- Testing
- Osteopathic Manipulative Treatment, Nursing Educational Care
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- University of Turin, Italy
Hypertension, Resistant Hypertension
Evaluation of Intestinal Microbiota Manipulation to Treat Resistant Hypertension
The gastrointestinal tract begins its colonization shortly after birth. During the first two years of life, gut microbiota is unstable and less diverse than in adulthood.
- Trial name
- VALORIS (NCT04398693)
- Testing
- Prebiotic
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hospital de Base
Crohns Disease
A Study to Evaluate the Effect of Fecal Transplant and Dietary Changes on Disease Activity in Patients With Crohn Disease on Advanced Therapies
Advanced therapies including biologics and small molecules target specific inflammatory pathways. IBD's multifactorial etiology means that blocking a single pathway may not be sufficient for all patients.
- Trial name
- BOOST-CD (NCT06890637)
- Testing
- Fecal Microbial Transplantation, Crohns Disease Exclusion Diet, Advanced therapy
- Where
- 6 sites in India
- Volunteers
- 168 people
- Sponsor
- All India Institute of Medical Sciences
Dyspepsia
Multi-dimensional Clinical and Pathophysiological Profiles of Patients With Functional Dyspepsia and Effect of Gut Microbiota Manipulation Using Rifaximin for Its Treatment
Functional dyspepsia (FD) is a common condition associated with significant morbidity, healthcare expenditure, work absenteeism and productivity, and reduced quality of life.
- Trial name
- NCT04302402
- Testing
- Rifaximin
- Where
- 2 sites in India
- Volunteers
- 132 people
- Sponsor
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
Irritable Bowel Syndrome
Irritable Bowel Syndrome and Osteopathic Manipulative Therapy
The Irritable Bowel Syndrome (IBS) is defined by a combination of abdominal pain, bowel dysfunction during recurrent periods of shorter or longer duration.
- Trial name
- IBSOMT (NCT02932111)
- Testing
- osteopathic session
- Where
- France
- Volunteers
- 157 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Primary Dysmenorrhea
Probiotics in Women With Primary Dysmenorrhoea
This study compares the effect of probiotics versus placebo in women with primary dysmenorrhoea
- Trial name
- NCT04119011
- Testing
- Probiotic
- Where
- Malaysia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Infant Conditions, Colic, Infantile
Efficacy of a Craniosacral Therapy Protocol in the Treatment of Infant Colic
This is a randomised controlled trial that aims to determine the effectiveness of craniosacral therapy for the treatment of infantile colic.
- Conditions
- Infant Conditions, Colic, Infantile, Gastro-Intestinal Disorder
- Trial name
- NCT03675763
- Testing
- Manual treatment
- Volunteers
- 58 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Colon Cancer Stage III, Colon Cancer Stage IV
The Effects of Chiropractic in Adults With Colon Cancer
The main objectives of this single-arm pilot trial are to investigate the feasibility of our protocol in terms of 1) recruitment, 2) adherence, 3) tolerability, 4) acceptability and 5) retention.
- Trial name
- CCX (NCT05310565)
- Testing
- HVLA cervical chiropractic adjustments
- Where
- United States
- Sponsor
- Life University