Clinical trials: Intestinal Motility
Erosive Esophagitis, Reflux Esophagitis
Proton Pump Inhibitor (PPI) Therapy for Newly Diagnosed Esophagitis
This study is being done to for two reasons: To learn about the effects (good and bad) esomeprazole (an FDA approved drug for reflux esophagitis) has on your esophagus when taken correctly.
- Conditions
- Erosive Esophagitis, Reflux Esophagitis, GERD
- Trial name
- EE (NCT00586963)
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Mayo Clinic
Barrett's Esophagus, Intestinal Metaplasia
Is the Neosquamous Epithelium "Normal" Following Endoscopic Ablation of Dysplastic Barrett's Esophagus?
The investigators propose a study comparing the morphological and functional aspects of the neosquamous epithelium (NSE) after ablative therapy for dysplastic Barrett's esophagus (BE) to that of native squamous epithelium in…
- Conditions
- Barrett's Esophagus, Intestinal Metaplasia, Gastroesophageal Reflux Disease (GERD)
- Trial name
- NCT01373125
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- University of North Carolina, Chapel Hill
Stomach Cancer
Effect of Mosapride Citrate on Gastrointestinal Motility After Laparoscopic Gastrectomy
"Mosapride citrate is a 5-hydroxytryptamine 4 receptor agonist, and is widely used as an agent to increase intestinal motility. Mosapride citrate has been demonstrated in in vitro and in vivo studies to increase both gastric and…
- Trial name
- NCT04493125
- Testing
- Mosapride citrate
- Where
- South Korea
- Volunteers
- 104 people
- Sponsor
- Gangnam Severance Hospital
Operation, Cesarean Section
Effect of Coffee Consumption on Pain and Intestinal Motility After Caesarean Section:
Objective The aim of this study was to investigate whether postoperative coffee intake affects pain levels and bowel motility in women undergoing cesarean delivery.
- Trial name
- NCT06359223
- Testing
- coffee consumption, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Inflammatory Bowel Diseases
Quantitative Assessment of Intestinal Motility on Bowel Ultrasound in Patients With Inflammatory Bowel Disease: a Feasibility, Observational, Cross-sectional, Monocentric Study
Inflammatory bowel diseases (IBD), such as ulcerative colitis (UC) and Crohn's disease (CD), are chronic, relapsing and destructive inflammatory disorder of the intestinal wall.
- Trial name
- MOTUS (NCT05719402)
- Testing
- non-interventional prospective cross-sectional observational study
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS San Raffaele
Gastro-Intestinal Disorder, Inflammatory Bowel Diseases
Image-Enhanced Endoscopy in the Gastrointestinal Tract
This study evaluates a range of endoscopic image enhancement techniques for assessing conditions involving the gastrointestinal tract.
- Conditions
- Gastro-Intestinal Disorder, Inflammatory Bowel Diseases, Gastro Esophageal Reflux, Atrophic Gastritis
- Trial name
- NCT04085211
- Where
- United Kingdom
- Volunteers
- 260 people
- Sponsor
- King's College Hospital NHS Trust
Food Selection
Pilot Study Using a Wireless Motility Capsule
Research suggests dietary fiber may decrease transit time through the gastrointestinal tract. Research studies traditionally use radio-opaque markers to determine gastric emptying, colonic transit, and whole gut transit time.
- Trial name
- NCT01102894
- Testing
- SmartPill
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Functional Colonic Disease, Fecal Incontinence
Effect of Lumbo-sacral Magnetic Stimulation on Colonic Motility
The purpose of this study is to evaluate the effect of sacral nerve magnetic stimulation on the colonic motility in healthy subjects, in incontinent and constipated patients.
- Trial name
- NCT00213317
- Testing
- lombo-sacral magnetic stimulation
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Functional Gastrointestinal Disorders, Overlap Syndromes
Overlap FGIDs and Genetic Polymorphism
1. To analyze the prevalence of overlap syndromes among NERD or RH, FD, and IBS patients, and to identify and to compare the differences in their characteristics and symptoms, and to determine their risk factors. 2.
- Trial name
- NCT04712617
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Postoperative Ileus, Postoperative Nausea
Assessing Gastric Motility and Distention in Postoperative Gastrointestinal Surgery Using Bedside Gastric Ultrasound: Predicting Risk of Aspiration Pneumonia, Ileus, Return of Bowel Function
Point-of-care gastric ultrasound will be used to measure stomach contents postoperative in patients who underwent colorectal surgery.
- Conditions
- Postoperative Ileus, Postoperative Nausea, Postoperative Complications, Postoperative Nausea and Vomiting
- Trial name
- NCT04747691
- Testing
- Bedside gastric ultrasound
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Eric Schwenk
Obesity, Obesity, Morbid
Biological Sample Repository for Gastrointestinal Disorders
The goal of this observational study has the purpose of collecting biological samples from obese patients undergoing evaluation for weight loss by means of medical or endoscopic therapies; and of post bariatric surgery patients…
- Conditions
- Obesity, Obesity, Morbid, Obesity, Primary, Gastro-Intestinal Disorder
- Trial name
- NCT05874726
- Testing
- Blood Collection, Urine Collection, Tissue Sample Collection
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Pichamol Jirapinyo, MD, MPH
Gastroesophageal Reflux Disease, Functional Bowel Disorders
Temple Registry for the Investigation of African American Gastrointestinal Disease Epidemiology
DESCRIPTION: Minimal data exists on the prevalence of gastroesophageal reflux disease in minority populations. Specific objectives of this K24 research project are to: (1) Provide an estimate of the prevalence of gastroesophageal…
- Trial name
- TRIAGE (NCT01262755)
- Testing
- Structured Interview
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Temple University
Dyspepsia
The Safety and Efficacy of Dexloxiglumide for the Relief of Symptoms of Functional Dyspepsia.
"Functional dyspepsia" has been defined loosely as "pain or discomfort centered in the upper abdomen." The symptoms can also include fullness, early satiety, bloating, belching, nausea, retching and vomiting.
- Trial name
- NCT00303264
- Testing
- dexloxiglumide, Nexium (esomeprazole)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Forest Laboratories
Gastrointestinal System Disease, Functional Bloating
Short-term Effect of Exercise and Self-manual Approaches to Bloating - Distention
Abdominal bloating and distension (ABD) are the most commonly gastrointestinal symptoms reported by patients with various functional gut disorders such as functional dyspepsia, irritable bowel syndrome and it is frequently…
- Conditions
- Gastrointestinal System Disease, Functional Bloating, Distension; Bowel, Gastrointestinal Motility Disorder
- Trial name
- NCT06347367
- Testing
- Group 1 (exercise and self-manual approaches targeting only the diaphragm muscles), Group 2 (exercise and self-manual approaches targeting both diaphragm and core muscles)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ege University
Colon Disease, Functional Constipation
Non-invasive Assessment of Colonic Motility
The current diagnostic process of colonic motility disorders often takes a long time and involves multiple invasive, painful and/or unnecessary diagnostic procedures.
- Conditions
- Colon Disease, Functional Constipation, Electroenterography, Slow Transit
- Trial name
- non-CoMoti (NCT04624334)
- Testing
- Elektro-Entero-Graphy procedure, EEnG Questionnaire, Gold Standard Questionnaire
- Where
- Netherlands
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Gastro Esophageal Reflux, Gastric Ulcer
Comparison Between Two Types of Sedation for Elective Upper Endoscopy Procedures
Sedation is defined as the act of administrating a sedative drug to produce a state of calm or sleep. Sedation is commonly given to a patient in hospital settings to provide a tolerable and pleasant experience by relieving…
- Conditions
- Gastro Esophageal Reflux, Gastric Ulcer, Sedation Complication
- Trial name
- NCT04410211
- Testing
- Sevoflurane, Midazolam injection
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Colon Polyp, Colon Disease
Endoscopy-related Phone Consultation During the COVID-19 Outbreak
The aim of this study is to evaluate patient and consultant experiences with phone consultations for endoscopy-related outpatient appointments during the COVID-19 outbreak.
- Conditions
- Colon Polyp, Colon Disease, Reflux, Gastroesophageal, Varices, Esophageal
- Trial name
- NCT04344964
- Testing
- None - NA
- Where
- Australia
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Austin Health
Hypertension, Depression
Patient-Centred Innovations for Persons With Multimorbidity - Ontario
The aim of Patient-Centred Innovations for Persons With Multimorbidity (PACE in MM) study is to reorient the health care system from a single disease focus to a multimorbidity focus; centre on not only disease but also the…
- Conditions
- Hypertension, Depression, Anxiety, Musculoskeletal Pain
- Trial name
- PACEinMM-ON (NCT02742597)
- Testing
- TIP / IMPACT Plus Care Coordination
- Where
- 9 sites in Canada
- Volunteers
- 175 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Peptic Ulcer, Dyspepsia
HEP-FYN 12-Years Follow-up
Aims: 1. Evaluate the long-term effect of screening and eradication of Helicobacter Pylori on the prevalence of dyspepsia, and, as secondary outcomes, to assess the effect on dyspepsia related health-care consumption and quality…
- Conditions
- Peptic Ulcer, Dyspepsia, Reflux
- Trial name
- NCT02001727
- Testing
- 13C-Urea breath test for Helicobacter Pylori, Questionaire
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Reflux Esophagitis
Study to Evaluate the Safety and Efficacy of X842 in Patients With Reflux Esophagitis
The purpose of the study is to investigate the efficacy and dose-effect relationship of X842 capsules at different dosages in the treatment of reflux esophagitis for 4 weeks in comparison with lansoprazole enteric-coated capsules.
- Trial name
- NCT04531475
- Testing
- X842, Lansoprazole
- Where
- 16 sites in China
- Volunteers
- 90 people
- Sponsor
- Jiangsu Sinorda Biomedicine Co., Ltd