Clinical trials: Intestinal Neoplasms
Breast Cancer
Breast Cancer and Its Relationship With the Microbiota
Breast cancer ranks first in women, and is the second cause of death in this gender. In addition to genetics, the environment contributes to the development of the disease, although the factors involved are not well known.
- Trial name
- MICROMA (NCT03885648)
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Colorectal Cancer
Development and Validation of Metabolic Biomarkers for Early Diagnosis, Prognosis, and Recurrence of Colorectal Cancer：MetBio-CRC
This prospective clinical observational study aims to construct a metabolite database specifically for colorectal cancer patients using metabolomics technology.
- Trial name
- NCT07068529
- Where
- China
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Shanghai Minimally Invasive Surgery Center
Colorectal Cancer
A Smartphone-Based Intervention to Improve Colorectal Cancer Screening in African American Men
The goal of this clinical trial is to test a new smartphone-based program designed to help African American men get screened for colorectal cancer (CRC).
- Trial name
- NCT06052202
- Testing
- CRC mHealth, Control
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- ISA Associates, Inc.
Colon Cancer
TVB 2640 for Resectable Colon Cancer Other Resectable Cancers; a Window Trial.
Primary Objective To evaluate the pharmacodynamic effects on metabolic endpoints (malonyl carnitine and tripalmitin levels) following short-term treatment with TVB-2640 in patients with resectable cancers Secondary Objectives To…
- Trial name
- NCT02980029
- Testing
- TVB-2640
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Mark Evers
Colon Cancer
The Comparison of Postoperative Pain After Colon Resection in Intravenous Patient-controlled Analgesia Between Conventional Mode and Optimizing B.I Mode With 'PAINSTOP' Equipment
Colon resection is one of the major surgery, the postoperative pain is so severe that it is necessary to use additional analgesics as well as a patient controlled analgesia (PCA).
- Trial name
- NCT03011359
- Testing
- Optimizing B.I (New) PCA mode, Conventional PCA mode
- Where
- South Korea
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Preleukemia, Myelodysplastic Neoplasm
Repurposing Metformin As a Leukemia-preventive Drug in CCUS and LR-MDS
This is a single-arm pilot study of the feasibility and safety of metformin in patients with clonal cytopenia of undetermined significance (CCUS) or lower-risk myelodysplastic neoplasms (LR-MDS).
- Conditions
- Preleukemia, Myelodysplastic Neoplasm, Cytopenia, Preleukemic Anemia
- Trial name
- NCT04741945
- Testing
- Metformin
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kirsten Grønbæk
Colorectal Cancer
Decision Aid to Technologically Enhance Shared Decision Making
Physicians face a challenge in promoting colorectal cancer screening (CRCS) in the face of multiple competing demands. A decision aid (DA) that clarifies patient preferences and improves decision quality could aid shared decision…
- Trial name
- DATES (NCT01514786)
- Testing
- Colorectal Web
- Where
- 14 sites in United States
- Volunteers
- 570 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Colorectal Cancer, Inflammation
Reducing Metabolic Dysregulation in Dyads
This study is a 6-month randomized controlled trail of diet modification designed to reduce chronic inflammation and reverse metabolic dysfunction among obese individuals with one or more polyps found at a colonoscopy screening.
- Conditions
- Colorectal Cancer, Inflammation, Nutrition Related Cancer
- Trial name
- REMEDY (NCT06117241)
- Testing
- IMAGINE HEALTHY
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Colorectal Cancer
Virtual Reality During Colonoscopy Procedures
Colorectal cancer (CRC) in the United States (US) is the fourth leading cause of cancer- related deaths. In Puerto Rico (PR), the incidence and mortality rate of CRC is higher (41% and 14%) in comparison to the mainland US (38%…
- Trial name
- VR (NCT06236386)
- Testing
- VR Experience
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Puerto Rico
Surgical Site Infection, Surgical Complication
Oral Antibiotic Bowel Preparation in Gynecologic Oncology Surgery
The purpose of this study is to investigate whether the use of a preoperative antibiotic bowel regimen is associated with a reduced risk of deep organ/space surgical site infection in gynecologic oncology surgery.
- Conditions
- Surgical Site Infection, Surgical Complication, Gynecologic Cancer
- Trial name
- NCT05210556
- Testing
- Diagnosed with Surgical Site Infection
- Where
- United States
- Volunteers
- 778 people, healthy volunteers welcome
- Sponsor
- WellSpan Health
Colorectal Cancer, Colorectal Adenoma
Comparison of Expression of Carcinogenesis-related Molecular Markers in the Patients With Colon Cancer and Polyp
A study of carcinogenesis-related molecular markers in the patients with colorectal cancer and colorectal adenoma.
- Trial name
- NCT05638542
- Where
- South Korea
- Volunteers
- 582 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Invasive Bladder Cancer
Intravenous Lidocaine for Cystectomy Procedures
Patients scheduled for a cystectomy at Charleston Area Medical Center (CAMC) will be enrolled into a randomized, double blinded clinical trial to assess if postoperative pain and ileus are reduced by perioperative intravenous…
- Trial name
- Lidocaine (NCT02924480)
- Testing
- Cystectomy, Lidocaine, Saline
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- CAMC Health System
Vasomotor Symptoms, Urinary Incontinence
Nurse-led Primary Healthcare Intervention Model in Women's Health Management in Hong Kong
The goal of this randomized clinical trial is to learn if a nurse-led primary healthcare intervention can help improve health management in women adults aged 45 to 64, and to develop an evidence-based primary healthcare model for…
- Conditions
- Vasomotor Symptoms, Urinary Incontinence, Anxiety, Depression - Major Depressive Disorder
- Trial name
- JCDATAZONEWH (NCT06628388)
- Testing
- Nurse-Led Risk-Based 5As Primary Healthcare Model, Minimal Intervention
- Where
- 3 sites in Hong Kong
- Volunteers
- 1,728 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Intestinal Cancer
Implementation of the Nurse Navigation Program
This study was conducted as a randomized controlled intervention study with repetitive measurements in a pretest-posttest order to examine the effect of nurse navigation program on compliance, quality of life and prevention of…
- Trial name
- rct (NCT05809661)
- Testing
- implementation of the nurse navigation program
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Kilis 7 Aralik University
Colorectal Cancer
#CuttingCRC: Barbershop-Based Trial & Colorectal Cancer
The goal of this behavior change focused, culture-specific, pilot, peer intervention is to target masculinity barriers to medical care (MBMC) considering a range of psychosocial factors associated with uptake of CRC screening…
- Trial name
- NCT03733197
- Testing
- Culture Specific, Control
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Colorectal Cancer
Efficacy of Perioperative Duloxetine as a Part of Multimodal Analgesia in Laparoscopic Colorectal Cancer Surgery
Our aim will be to evaluate the efficacy of perioperative Duloxetine in decreasing acute postoperative pain after laparoscopic colorectal cancer surgery and its role in reducing postoperative morphine requirements
- Trial name
- NCT04294953
- Testing
- Duloxetine
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
HPV Infection, Anal Cancer
Identification of Molecular Signatures of High-risk Oncogenic HPV and Study of Their Associations With the Presence of High-grade Lesions and/or Anal Cancer 10 Years After Inclusion in the ANRS IPERGAY Trial
HPVsign is a cross-sectional, non-comparative, multicenter study involving all participants included in the HPV substudy of the ANRS IPERGAY trial.
- Trial name
- HPVsign (NCT06522256)
- Testing
- High-resolution anoscopy
- Where
- 3 sites in France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
Colorectal Cancer
The Northern-European Initiative on Colorectal Cancer
Colorectal cancer (CRC) is a major burden in western countries. The disease develops from precursor lesions during a long time-interval.
- Trial name
- NordICC (NCT00883792)
- Testing
- Colonoscopy
- Where
- 7 sites in United States, Iceland and 4 more
- Volunteers
- 95,000 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Acute Myelogenous Leukemia, Ovarian Cancer
Galinpepimut-S in Combination With Pembrolizumab in Patients With Selected Advanced Cancers
To evaluate the safety, tolerability, and anti-tumor activity of galinpepimut-S in combination with pembrolizumab in patients with selected advanced cancers.
- Conditions
- Acute Myelogenous Leukemia, Ovarian Cancer, Colorectal Cancer, Triple-negative Breast Cancer
- Trial name
- NCT03761914
- Testing
- galinpepimut-S, pembrolizumab, Montanide
- Where
- 12 sites in United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Sellas Life Sciences Group
Colorectal Cancer
Ginger for Colorectal Cancer Prevention
The purpose of this study is to determine if ginger root extract when taken daily for 28 days is able to decrease levels of inflammatory chemicals called eicosanoids in the gut tissue of people who are at normal risk and those at…
- Trial name
- NCT01344538
- Testing
- Ginger Root Extract (Pure Encapsulations)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Michigan