Clinical trials: Intestinal Obstruction and Ileus
Post Operative Patients
The Food Network Effect
The goal of this clinical trial is to learn if exposure to food related visual stimuli during the postoperative period can improve gastrointestinal recovery after abdominal surgery in adult patients.The main questions it aims to…
- Trial name
- NCT07618559
- Testing
- Food Related Visual Stimuli Exposure
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Casey Morehouse, DO
Ileus
Acupuncture and Post-Operative Ileus
Postoperative ileus, the transient cessation of normal bowel function, is a universal aspect of colon surgery. Its occurrence may lead to increased patient discomfort and additional time and cost to hospital stay.
- Trial name
- NCT00655317
- Testing
- Acupuncture
- Where
- 2 sites in United States
- Volunteers
- 107 people
- Sponsor
- Mayo Clinic
Postoperative Ileus
The Effect of Rocking Chair Movement on the Start of Bowel Functions in Patients With Gastrointestinal System Surgery
The Effect of Rocking Chair Movement on the Start of Bowel Functions in Patients With Gastrointestinal System Surgery The research will be carried out as a randomized controlled experimental study in patients with open…
- Trial name
- NCT04466319
- Testing
- Rocking Chair
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Eskisehir Osmangazi University
Rectal Cancer Surgery, Middle and Low Rectal Cancer
Pelvic Floor Peritoneal Closure to Prevent Postoperative Ileus in Mid-Low Rectal Cancer Surgery
The goal of this clinical trial is to determine whether closing the pelvic floor peritoneum during laparoscopic radical resection of mid-low rectal cancer can reduce the incidence of postoperative ileus.
- Conditions
- Rectal Cancer Surgery, Middle and Low Rectal Cancer, Intestinal Obstruction, Ileus
- Trial name
- TOWER-1 (NCT07432542)
- Testing
- Pelvic floor peritoneum reconstruction
- Where
- China
- Volunteers
- 516 people
- Sponsor
- Sun Yat-sen University
Ileus
Phase 2 RCT of Alvimopan vs. Placebo After CRS/HIPEC
The purpose of this study is to investigate the ability of alvimopan to reduce the time to return of bowel function in patients undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.
- Trial name
- ILEUS (NCT03352414)
- Testing
- Alvimopan
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of California, San Diego
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Intestinal Pseudo-Obstruction, Short Bowel Syndrome
Improved Quality of Life in Children With Intestinal Failure
Children with intestinal failure have a lack of tolerance for food in the intestine. The children are dependent on intravenous nutrition over a long period of time period to ensure growth and development.
- Conditions
- Intestinal Pseudo-Obstruction, Short Bowel Syndrome, Malabsorption Syndrome Autoimmune Enteropathy, Bacterial Overgrowth
- Trial name
- NCT04981262
- Testing
- Stimulance
- Where
- Norway
- Volunteers
- 56 people
- Sponsor
- Oslo University Hospital
Intestinal Atresia, Necrotizing Enterocolitis
The Role of Indocyanine Green Angiography Fluorescence on Intestinal Resections in Pediatric Surgery.
Background: Intestinal resections are commonly performed in the pediatric population. Perfusion of the bowel is one of the most important factors determining the viability of an intestinal anastomosis.
- Conditions
- Intestinal Atresia, Necrotizing Enterocolitis, Hirschsprung Disease, Gastroschisis
- Trial name
- NCT04020939
- Testing
- SPY imaging, Indocyanine Green
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Ileus
Safety and Efficacy of Ipamorelin for Management of Post-Operative Ileus
The purpose of this study is to determine if ipamorelin is safe and effective in the management of post-operative ileus.
- Trial name
- NCT00672074
- Testing
- Ipamorelin
- Where
- 19 sites in United States
- Volunteers
- 117 people
- Sponsor
- Helsinn Therapeutics (U.S.), Inc
Ileus
Prevention of Ileus After Gynecologic Surgery Using Chewing Gum
This study will attempt to determine if the use of chewing gum can cause the early return of bowel function after gynecologic surgery.
- Trial name
- NCT00831246
- Testing
- chewing gum - Extra Winterfresh, Standard Post-Op Care
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Aultman Health Foundation
Post Operative Ileus
Predictive Validity of Acoustic Gastrointestinal Surveillance (AGIS) in Post-Operative Feeding
This study will measure the accuracy of a disposable, non-invasive device for the continuous monitoring of abdominal sounds, called the AGIS sensor (Acoustic Gastro-Intestinal Surveillance) in predicting patients' intolerance to…
- Trial name
- AGIS (NCT02065583)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- VA Greater Los Angeles Healthcare System
Paralytic Ileus
Effects of Gum Chewing on Recovery of Bowel Function Following Abdominal Surgery for Endometrial and Ovarian Cancer
Following extensive abdominal surgery for the treatment of endometrial or ovarian cancer, paralytic ileus frequently develops. Gum chewing can promotes the return of bowel function through the cephalic-vagal reflex and increased…
- Trial name
- NCT01389986
- Testing
- Gum chewing
- Where
- Thailand
- Sponsor
- Chiang Mai University
Cholelithiases, Nursing Caries
The Effect of Early Mobilization and Fluid Consumption on Bowel Movements After Cholecystectomy
Objective: The aim of this study was to determine the effect of early mobilization with consumption of tea, coffee, and warm water on bowel movements in patients who had laparoscopic cholecystectomy surgery.
- Conditions
- Cholelithiases, Nursing Caries, Perioperative Complication, Bowel Ileus
- Trial name
- NCT05800886
- Testing
- Early mobilization and tea consumption, Early mobilization and coffee consumption, Early mobilization and warm water consumption
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Gazi University
Intestinal Pseudo-Obstruction, Manipulation, Osteopathic
Rib Raising for Post-operative Ileus
We are conducting a randomized controlled trial the use of rib raising for post-operative ileus. Rib raising is an osteopathic manipulative technique (OMT).
- Conditions
- Intestinal Pseudo-Obstruction, Manipulation, Osteopathic, Postoperative Care, Postoperative Nausea and Vomiting
- Trial name
- NCT03662672
- Testing
- Rib raising and lumbar release
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Rutgers, The State University of New Jersey
Small Bowel Obstruction, Intestinal Obstruction and Ileus
The Effect of Nasogastric Tube Placement on Complications in Patients With Small Bowel Obstruction - the SBO-TUBE Trial
Background: Small bowel obstruction (SBO) is a surgical emergency where the normal continuous bowel movements are hindered and approximately 8000-9000 patients visit the emergency department every year in Sweden due to SBO.
- Trial name
- SBO-TUBE (NCT07574515)
- Testing
- Nasogastric tube placement
- Where
- 3 sites in Sweden
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Linkoeping
Cystic Fibrosis, Lung Disease
Benefits and Risks of Newborn Screening for Cystic Fibrosis
Although cystic fibrosis (CF) is the most common, life-threatening autosomal recessive genetic disorder of the white population, there are often delays in diagnosis and hence start of treatment.
- Conditions
- Cystic Fibrosis, Lung Disease, Pseudomonas Infections
- Trial name
- NCT00014950
- Testing
- CF newborn screening
- Where
- 2 sites in United States
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Ileus, Opioid Use
Postoperative Opioid Use and Ileus Occurrence---A Case Control Study
Postoperative ileus (POI) is a significant complication after colorectal surgery, with reported incidence ranging from 10~30%, leading to increased morbidity, hospital length of stay, and thus medical cost.
- Trial name
- NCT05262569
- Testing
- ileus
- Where
- China
- Volunteers
- 596 people
- Sponsor
- Peking University People's Hospital
Paralytic Ileus, Critically Ill
Efficacy of PRUcalopride in Critically Ill Patients With Paralytic ILeus
Paralytic ileus is a common intestinal dysfunction in critically ill patients. There are still no established the effective medications except correcting the primary causes and prokinetics trial which limited in efficacy and…
- Trial name
- EPRUCIL (NCT04190173)
- Testing
- Prucalopride
- Where
- Thailand
- Volunteers
- 62 people
- Sponsor
- Prince of Songkla University
NEC, Gastroschisis
Neokare Safety and Tolerability Assessment in Neonates With GI Problems
With an increasing body of evidence to support a causal link between drinking milk that contain cow's milk protein (CMP) and the development of gastrointestinal disturbance in infants, many clinicians avoid the use of CMP…
- Conditions
- NEC, Gastroschisis, Intestinal Perforation, Atresia, Intestinal
- Trial name
- NCT05293353
- Testing
- NeoKare Breast Milk Fortifier
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Hernia, Ventral, Ileus
The Impact of Sugammadex on Ileus After Abdominal Wall Reconstruction
The aim of the study is to determine if the usage of sugammadex would reduce the time to return of bowel function when compared to standard of care (neostigmine/glycopyrrolate) when used for neuromuscular blockade reversal in…
- Trial name
- NCT05985343
- Testing
- Neostigmine / Glycopyrrolate, Sugammadex
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- Clayton Petro