Clinical trials: Intestinal Polyps, open to volunteers
Familial Adenomatous Polyposis
A Personalized Surveillance and Intervention Protocol for Patients With Familial Adenomatous Polyposis That Have Undergone (Procto)Colectomy
The purpose of this study is to determine the efficacy and safety of a personalised surveillance and intervention protocol for patients with familial adenomatous polyposis (FAP) that have undergone (procto)colectomy.
- Trial name
- NCT04678011
- Testing
- Personalized surveillance and intervention protocol
- Where
- 2 sites in United States, Netherlands
- Volunteers
- 1,000 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Colonic Polyps, Artifical Intelligence
The Long-term Effect of Artificial Intelligence-assisted Colonoscopy on Risk of Metachronous Advanced Colonic Lesion
The goal of this prospective study is to to evaluate the prevalence of metachronous advanced colonic lesions in subsequent surveillance colonoscopies in patients who had previously undergone AI-assisted colonoscopy to…
- Conditions
- Colonic Polyps, Artifical Intelligence, Advanced Metachonous Colonic Lesion
- Trial name
- NCT07467928
- Testing
- Suveillance colonoscopy
- Where
- Hong Kong
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Colorectal Cancer Screening, Colon Polyps and Adenomas
Artificial Intelligence (AI) Technology May Help Patients to Understand Bowel Preparation Better Before They go for Colonoscopy.This Study Attempts to Leverage AI Chatbot in Counselling Patients to Improve Bowel Cleanliness, Reduce Anxiety as Well as Increase Procedural Satisfaction
Traditional pre-colonoscopy counselling requires significant time from healthcare workers to explain procedures, limiting efficiency and patient turnover.
- Conditions
- Colorectal Cancer Screening, Colon Polyps and Adenomas, Bowel Preparation Quality, Artificial Intelligence (AI)
- Trial name
- NCT06905782
- Testing
- AI chatbot study arm, Traditional counselling study arm
- Where
- Malaysia
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Colorectal Cancer, Colorectal Adenoma
Early Diagnosis of Colorectal Cancer Based on a Non-invasive Metabolomics Profile
Colorectal cancer is the most frequent tumor in our environment if both sexes are considered together. Every year almost 800 cases are diagnosed in the districts of Tarragona.
- Conditions
- Colorectal Cancer, Colorectal Adenoma, Colorectal Polyp, Healthy
- Trial name
- EarlyCRC (NCT06452745)
- Testing
- Colonoscopy, Urine and FOBT collection
- Where
- 2 sites in Spain
- Volunteers
- 2,000 people
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Colon Polyp, Adenoma
Six Versus Twelve Month Index Follow-up After Large Colon Polyp Resection
The study will compare the use of a 6-month follow-up vs a 12-month follow-up after the removal of a large non-pedunculated polyp 20-50mm in size and without high grade dysplasia.
- Conditions
- Colon Polyp, Adenoma, Serrated Polyp, Recurrence, Local Neoplasm
- Trial name
- STARLING (NCT07198945)
- Testing
- 6-month follow-up, 12-month follow-up
- Where
- 10 sites in United States, Canada and 1 more
- Volunteers
- 546 people
- Sponsor
- Indiana University
Polyps, Adenoma Colon
Early DiAgnosis Real-Time Healthcare System for CANcer Trial
The purpose of the study is to assess whether the AI characterisation system of the CADDIE device improves the endoscopists accuracy in the optical diagnosis of diminutive colorectal polyps in the bowel during colonoscopy.
- Conditions
- Polyps, Adenoma Colon, Colorectal Polyp, Colon Polyp
- Trial name
- EARTHSCAN (NCT05064124)
- Testing
- CADDIE - Computer Aided Detection and Diagnosis for Intelligent Endoscopy
- Where
- United Kingdom
- Volunteers
- 420 people
- Sponsor
- University College, London
Intestinal Polyps
Effect of Non-invasive Neuromodulation on the Quality of Intestinal Cleansing
To clarify whether non-invasive neuromodulation for assisted bowel preparation can improve the quality of bowel preparation, to explore the possible mechanisms by which TEA improves the quality of bowel preparation, and to assess…
- Trial name
- NCT07290816
- Testing
- Intestinal pacing + ST36 acupoint stimulation
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Shanghai East Hospital
Colon Polyp, Colorectal Carcinoma
Testing the Effects of Exercise on Colorectal Cancer Development After Treatment With Pelvic Radiation Therapy for Prostate Cancer
This clinical trial evaluates the effects of exercise therapy on signs of colorectal cancer in colon tissue and blood in people who completed pelvic radiation therapy for prostate cancer.
- Conditions
- Colon Polyp, Colorectal Carcinoma, Localized Prostate Carcinoma, Stage I Prostate Cancer AJCC v8
- Trial name
- NCT07790718
- Testing
- Aerobic Exercise, Biopsy Procedure, Biospecimen Collection
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- City of Hope Medical Center
Colorectal Cancer, Colorectal Polyp
Safety Of ColoRectal Assessment and Tumor Evaluation by Colon Capsule Endoscopy
Following European guidelines patients undergoing colonoscopy in one of Odense University Hospitals units will now be offered a colon capsule endoscopy (CCE) in case of incomplete examinations.
- Trial name
- SOCRATEC (NCT04307901)
- Testing
- Colon capsule endoscopy
- Where
- Denmark
- Volunteers
- 600 people
- Sponsor
- Odense University Hospital
Colonoscopy, Colorectal Neoplasms
Efficacy of CAD in Screening Colonoscopy to Reduce the Risk of Advanced Adenoma at 3 Years.
The occurrence of interval cancers after colonoscopy raises the possibility of missed lesions. High- performance computer aided diagnosis (CAD) systems have been specially designed for the detection of colorectal lesions (CAD for…
- Conditions
- Colonoscopy, Colorectal Neoplasms, Intestinal Polyps
- Trial name
- IA-COLO 2 (NCT07299071)
- Testing
- Standard colonoscopy, Colonoscopy CADe
- Where
- 15 sites in France
- Volunteers
- 592 people
- Sponsor
- University Hospital, Bordeaux
Familial Adenomatous Polyposis
Colorectal Adenoma Canceration in FAP
The current internationally accepted treatment method for familial adenomatous polyposis is prophylactic total colorectal resection combined with endoscopic follow-up.
- Trial name
- NCT04531930
- Testing
- surgery, enhanced colonoscopy, self choosed methods
- Where
- China
- Volunteers
- 124 people
- Sponsor
- Changhai Hospital
Colorectal Neoplasm, Endoscopic Mucosal Resection
ESD for Colorectal LSL Using a Selective Strategy - a Prospective Cohort Study
Colonic Laterally spreading lesions (LSL) => 20mm are at high risk to progress to cancer. Overt stigmata of submucosal invasive cancer (SMIC) has been well characterized and includes ulceration and surface pit pattern changes as…
- Trial name
- COVERT (NCT04008407)
- Testing
- Endoscopic Submucosal Dissection, Endoscopic Mucosal Resection
- Where
- Australia
- Volunteers
- 391 people
- Sponsor
- Western Sydney Local Health District
Artificial Intelligence, Colonic Adenoma
Artificial Intelligence-Assisted Colonoscopy in Colorectal Cancer Screening in a General Hospital
Cancer can develop in the colon, or large bowel. Examination of the colon with a tube fitted with a camera is called a colonoscopy. Colonoscopy allows detection of small growths in the colon, called "polyps".
- Conditions
- Artificial Intelligence, Colonic Adenoma, Colonic Neoplasms, Colonic Polyp
- Trial name
- Delta-AI (NCT06792292)
- Testing
- conventional colonoscopy procedure, artificial intelligence-assisted colonoscopy procedure
- Where
- Belgium
- Volunteers
- 765 people, healthy volunteers welcome
- Sponsor
- Chirec
Manual Pressure, Repositioning
Water Exchange and CO2 Insufflation With Abdominal Compression Device to Reduce Manual Assistance
The goal of this trial is to evaluate whether water exchange colonoscopy and CO2-insufflation colonoscopy with an abdominal compression device (Maxbelt me3 type, Nippon Sigmax Co., Tokyo, Japan) can achieve a significantly lower…
- Conditions
- Manual Pressure, Repositioning, Colonoscopy, Colon Polyp
- Trial name
- NCT06496958
- Testing
- CO2 insufflation with an abdominal compression device, Water exchange colonoscopy
- Where
- 2 sites in Taiwan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Evergreen General Hospital, Taiwan
Familial Adenomatous Polyposis (FAP)
A Safety Study of ST316 in Participants With Familial Adenomatous Polyposis (FAP).
This is a Phase 1b, open- label, dose-optimization study evaluating ST316 in adult participants with familial adenomatous polyposis (FAP) who have undergone colectomy and have recurrent polyps.
- Trial name
- FAP (NCT07729371)
- Testing
- ST316 IV
- Volunteers
- 40 people
- Sponsor
- Sapience Therapeutics
Ulcerative Colitis, Inflammatory Bowel Disease (IBD)
Cohort of Patients With Ulcerative Colitis or Polyps Followed in CHU de Bordeaux Associated With a Biocollection - COLIBRI
Ulcerative colitis (UC) is a chronic disease characterized by acute episodes of bloody diarrhea with varying degrees of severity. The most feared event, acute severe UC, can lead to life-threatening and systemic complications.
- Conditions
- Ulcerative Colitis, Inflammatory Bowel Disease (IBD), Acute Severe Ulcerative Colitis
- Trial name
- COLIBRI (NCT07082231)
- Testing
- Blood sample, biopsy
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Bordeaux
Colorectal Neoplasms, Colonic Polyps
A Novel Clinical Decision Support Tool to Predict Submucosal Invasive Cancer Within Large Non-Pedunculated Colorectal Polyps
Colorectal cancer can be effectively prevented by removal of pre-malignant polyps during colonoscopy. Large (>=20mm) non-pedunculated colorectal polyps (LNPCPs) require careful assessment before treatment.
- Trial name
- NCT07705880
- Where
- Belgium
- Volunteers
- 886 people
- Sponsor
- University Hospital, Ghent
Colonic Polyp, Colonic Sessile Serrated Lesion
The CARMA Technique Study
Colonoscopic removal of polyps is an important and well-established tool in the prevention of colorectal cancers. However, high polyp recurrence rates after endoscopic resection, with resultant development of interval cancers…
- Trial name
- NCT05099432
- Testing
- CARMA technique
- Where
- Australia
- Volunteers
- 60 people
- Sponsor
- Princess Alexandra Hospital, Brisbane, Australia
Polyp of Colon, Artificial Intelligence (AI)
Video/Image Library of Endoscopy Procedures for the Development of AI-empowered Endoscopy Quality Reporting and Educational Modules
The goal of this observational study is to establish a video/image library dataset of complete endoscopy or partial colonoscopy procedures for patients with rectal cancer or inflammatory bowel disease (IBD).
- Trial name
- Videotheque (NCT06822816)
- Where
- Canada
- Volunteers
- 10,000 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Polyp of Colon, Crohn Disease
Lesion Size Measurement During Gastrointestinal Endoscopies
The goal of this prospective observational study is to assess the accuracy and reliability of laser readings obtained through AccuMeasure, in comparison to other measurements performed by gastroenterologists.
- Trial name
- AccuMeasure (NCT07770425)
- Where
- Canada
- Volunteers
- 3,000 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)