Clinical trials: Intestine
Colonoscopy, Colon Adenoma
Low Residue Diet During 3 Days vs 1 Day Prior Colonoscopy
Colonoscopy is the gold-standard for the evaluation of the colorectal mucosa. Colonoscopy quality indicators are the adenoma detection rate, the rate of cecal intubation and the bowel preparation.
- Conditions
- Colonoscopy, Colon Adenoma, Colorectal Neoplasms, Inflammatory Bowel Diseases
- Trial name
- NCT03763266
- Testing
- 1 day low residue diet, 3 day low residue diet
- Where
- Spain
- Volunteers
- 858 people, healthy volunteers welcome
- Sponsor
- Parc Taulí Hospital Universitari
Colorectal Cancer
Informed Choice - Compass
The primary objective of this study is to evaluate the impact of a theoretically grounded video that includes information about CRC screening modality choices on CRC screening rates and time adherent to CRC guidelines.
- Trial name
- NCT05246839
- Testing
- Brief Video, Brief Video Plus
- Where
- 39 sites in United States
- Volunteers
- 1,823 people, healthy volunteers welcome
- Sponsor
- Exact Sciences Corporation
Colorectal Carcinoma
Blood Test (Guardant Shield™) for Screening of Colorectal Cancer in Underserved Patients
This clinical trial evaluates the use of a blood test (Guardant Shield™) for colorectal cancer screening. Colorectal cancer is the third leading cancer and cause of death in the United States.
- Trial name
- NCT05716477
- Testing
- Biospecimen Collection, Survey Administration
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Anal Incontinence
Anal Incontinence and Its Impact on Quality of Life and Physical Activity Among Hungarian Women and the Hungarian Language Validation of the International Consultation on Incontinence Modular Questionnaire-Bowels (ICIQ-B)
The aim of the study is to assess the prevalence of anal incontinence among Hungarian women who have given birth at least once before, and to examine the impact of anal incontinence on the quality of life and physical activity of…
- Trial name
- NCT06423222
- Where
- Hungary
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Healthy, Overweight and Obesity
Westlake Precision Nutrition Study
This is a dietary intervention study, which aims to explore different diet challenges for glucose metabolism, including carbohydrates and intermittent fasting (IF) dietary pattern.
- Trial name
- NCT05054153
- Testing
- refined carbohydrate breakfast, whole grain breakfast, intermittent fasting
- Where
- China
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Westlake University
Influenza H1N1
Efficacy and Safety of Vaccination Against Influenza H1N1 in Patients With Inflammatory Bowel Diseases (IBD) Treated Immunomodulators and Biologics
The spread of Influenza H1N1 has prompted the development of vaccines against this virus. IBD patients are at increased risk of developing complications of Influenza H1N1.
- Trial name
- NCT01019837
- Testing
- Focetria (Monovalent MF59-Adjuvanted vaccine)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Spinal Cord Injuries, Constipation
Use of a Prokinetic Agent as an Adjunct to Thrice Weekly Bowel Care After SCI
To measure a baseline for each subject, an abdominal x-ray (KUB) was performed, the SCI Bowel Survey and Treatment Satisfaction Questionnaire (TSQM) were administered and the subject's weight determined.
- Conditions
- Spinal Cord Injuries, Constipation, Neurogenic Bowel
- Trial name
- TWBC (NCT04671030)
- Testing
- Neostigmine and Glycopyrrolate, Iontophoresis
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Binge Drinking
The Brain, the Bug, and the Binge: the Interplay Between Binge Drinking, Gut Microbiota, and Brain Functioning
Adolescence and youth are periods of significant maturational changes which seems to involve greater susceptibility to disruptive events in the brain such as binge drinking (BD).
- Trial name
- NCT05946083
- Testing
- Inulin Intervention, Maltodextrin Intervention
- Where
- Portugal
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Minho
Neoadjuvant Chemoradiotherapy
Hyperpolarized 13C-MRI and Radiomics in Rectal Cancer
This study is testing new imaging and analysis methods to improve how doctors predict treatment response in rectal cancer patients receiving chemoradiotherapy.
- Trial name
- DNP_RECA (NCT07730541)
- Testing
- Hyperpolarized 13C-MRI (HP 13C-MRI)
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Hemorrhoids
Laser Hemorrhoidoplasty Versus Open Surgical Hemorrhoidectomy in Second and Third Degree Piles
The study aims to compare the pain , duration of intervention and long term outcomes of laser hemorrhoidoplasty versus open surgical hemorrhoidectomy
- Trial name
- NCT05770141
- Testing
- laser hemorrhoidoplasty, open surgical hemorrhoidectomy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Colorectal Cancer, Colorectal Adenoma
The Implementation of Genetic Risk for Colorectal Cancer Screening
The goal of this study is to investigate genetic risk for colorectal cancer utilizing polygenic risk scores (PRS) for adults over 45 who have not received their first colonoscopy. The main questions it hopes to address are: 1.
- Conditions
- Colorectal Cancer, Colorectal Adenoma, Colorectal Polyp
- Trial name
- PRO-GENE-COLON (NCT07621757)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
HNPCC
Uncertain Genetic Test Results for Lynch Syndrome
Background: Individuals have varying tolerances for receiving ambiguous information. However, not much is known about how ambiguous genetic testing information is received.
- Trial name
- NCT01646112
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Incontinence Associated Dermatitis
Development of a Risk Assessment Tool for Incontinence-associated Dermatitis (IAD): a Cohort Study on the Predictive Performance of Risk Factors for IAD
Objective: The primary goal of this prospective cohort study is to collect data on specific factors, including age, sex, stool consistency, etc. and assess their association with the development of IAD.
- Trial name
- INCONTECT (NCT06978751)
- Where
- 7 sites in Belgium, Sweden
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Juvenile Idiopathic Arthritis, Diabetes type1
Host-microbiota-environment Interactions
Two types of inflammatory and autoimmune diseases (excluding monogenic diseases) can be distinguished in children: those similar to adult diseases but with an early onset (type 1 diabetes, inflammatory diseases of the…
- Conditions
- Juvenile Idiopathic Arthritis, Diabetes type1, Inflammatory Bowel Diseases
- Trial name
- MIP-1 (NCT05176795)
- Testing
- Stool sample
- Where
- France
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Colorectal Cancer, Familial Adenomatous Polyposis
DNA Adductomics for Colorectal Cancer Investigation
This project seeks to identify DNA-adducts in colon tissue from different groups of patients with CRC scheduled for complete or partial colon resections. Other patients scheduled for resection of the colon serve as controls.
- Conditions
- Colorectal Cancer, Familial Adenomatous Polyposis, Hereditary Non-polyposis Colon Cancer, Lynch Syndrome
- Trial name
- adductomics (NCT04865601)
- Testing
- resectomy of the colon
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Postprandial Hyperglycemia, Metabolic Disorder, Glucose
Westlake N-of-1 Trials for Macronutrient Intake
This is a dietary intervention study in students and staff of Westlake University, which is designed to provide evidence in support of N-of-1 methods as an approach to advance personalized nutrition.
- Trial name
- WE-MACNUTR (NCT04125602)
- Testing
- High fat low carbohydrate diet, Low fat high carbohydrate diet
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Westlake University
Advanced Cancers
End of Life Treatment Preferences of Latino Medicare Beneficiaries With Cancer
Objectives: The primary objective of the research project is to investigate how declining health status influences the end-of-life (EOL) treatment preferences in Latino Medicare beneficiaries with cancer and to examine if and how…
- Trial name
- NCT01389830
- Testing
- Telephone Survey
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Microbiota, Cancer
DASH INtervention to INvestigate the Gut
The study investigators will recruit a generally healthy sample of 112 black and white adults from Birmingham, AL to participate in a 28-day randomized, controlled feeding study.
- Trial name
- DINING (NCT04538482)
- Testing
- DASH Diet, standard American diet
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Colorectal Cancer
Increasing Colorectal Cancer Screening Uptake With a Patient Navigator
Patients who receive tailored navigation (consisting of a letter and patient navigation services) and get screened will be significantly greater than the control group who receives treatment as usual.
- Trial name
- NCT01506687
- Testing
- Health counselling by nurse navigator, Usual primary care counselling
- Where
- Canada
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Cancer Care Ontario
Colorectal Neoplasms
Hepatic Arterial Infusion Pump Chemotherapy Combined With Systemic Chemotherapy (PUMP-IT)
The PUMP-IT study is designed to prove the feasibility of HAIP chemotherapy with concomitant standard systemic chemotherapy (FOLFOX and FOLFIRI) in the Netherlands.
- Trial name
- PUMP-IT (NCT04552093)
- Testing
- Floxuridine, Tricumed IP2000V infusion pump
- Where
- Netherlands
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- The Netherlands Cancer Institute
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