Clinical trials: Intestine
Healthy, Overweight and Obesity
Westlake Precision Nutrition Study
This is a dietary intervention study, which aims to explore different diet challenges for glucose metabolism, including carbohydrates and intermittent fasting (IF) dietary pattern.
- Trial name
- NCT05054153
- Testing
- refined carbohydrate breakfast, whole grain breakfast, intermittent fasting
- Where
- China
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Westlake University
Healthy Conditions
Diet Induced Intestinal Mucosal Adaptation
Human beings are 'omnivores' meaning that all principal components of food (i.e. the macronutrients: carbohydrates, fat, proteins) can be assimilated by the gastrointestinal tract.
- Trial name
- NCT02088853
- Testing
- high fat diet (hfd), then high carbohydrate diet, high carbohydrate diet, then high fat diet
- Where
- Sweden
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Microbial Colonization
Impact of Quinoa Milk Fermented With Lactic Acid Bacteria From Foods on Human Oral and Intestinal Flora
The demand for alternatives to dairy products has increased in recent years and a lot of proposals for vegetable milk and yogurt products have taken place in the market.
- Trial name
- NCT04280731
- Testing
- fermented quinoa
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lund University
Obesity, Diabetes Mellitus, Type 2
Human Intestinal Peptides Evaluation and Research
The HIPER-1 study is a single centre cross sectional study in which a total of 240 participants (in different metabolic states and surgical models) will receive an Oral Mixed Meal Tolerance Test (OMTT).
- Trial name
- HIPER (NCT02532829)
- Testing
- blood sample analysis
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Turkish Metabolic Surgery Foundation
Duodenal Diseases, White Spot Lesion
İmportance of Scattered White Spots Detected in the Duodenum and Their Relationship wıth Zonulin
With our study, we aimed to determine whether there is a correlation between zonulin, which plays a crucial role in intestinal barrier function and is implicated in the etiopathogenesis of many chronic and autoimmune diseases…
- Trial name
- NCT06200129
- Testing
- sws grade 1, sws grade 2, control
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Stoma Ileostomy, Stoma Colostomy
The Effect of Education on Self-Efficacy and Adaptation to Stoma of Individuals With Stoma
The aim of this study is to determine the effect of stoma care training given at home via videoconferencing after discharge on the self-efficacy and compliance with stoma of individuals with stoma.
- Conditions
- Stoma Ileostomy, Stoma Colostomy, Self Efficacy, Adjustment
- Trial name
- NCT05531331
- Testing
- At home education via video conferencing
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara University
Intestinal Permeability
Establishing and Validating a Meal-provoked Intestinal Permeability Test for Nutritional and Metabolic Health Clinical Research.
Development of Intestinal Permeability Tests for Clinical Nutrition and Metabolic Health Studies
- Trial name
- Gut-Perm (NCT07066176)
- Testing
- Aspirin, Mixed meal beverage
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Laval University
Colorectal Cancer
Maximizing Yield of the Fecal Immunochemical Test for Colorectal Cancer Screening
Colorectal cancer (CRC) is a leading cause of cancer death in the United States. Screening for CRC reduces CRC mortality, yet rates of screening in the United States remain low.
- Trial name
- MY-FIT (NCT01634126)
- Testing
- 1 FIT kit, 2 FIT kit
- Where
- United States
- Volunteers
- 2,761 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Vagus Nerve Autonomic Disorder, Heart Rate
Balance, Autonomic Response, and Sensory Modulation to Dosage of Mechanical Vagal Stimulation in Healthy Adults
The vagus nerve (VN) plays a crucial role in regulating vital functions (heart rate, blood pressure, digestion, and immune response) and maintaining communication between internal organs and the brain.
- Conditions
- Vagus Nerve Autonomic Disorder, Heart Rate, Pain, Equilibrium; Disorder, Labyrinth
- Trial name
- BARVANS (NCT06541808)
- Testing
- mechanical Vagus Nerve Stimulation (Low Intensity), mechanical Vagus Nerve Stimulation (Intermediate Intensity), mechanical Vagus Nerve Stimulation (High Intensity)
- Where
- Austria
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Hepatocellular Cancer, Non-small Cell Lung Cancer
Profile of Soluble and Cellular Biomarkers and of Functional Imaging During Antiangiogenic Therapies in Cancer Patients
Tumour angiogenesis has been identified to play a critical role in tumour growth and this knowledge has led to the identification of new targets for cancer therapy.
- Conditions
- Hepatocellular Cancer, Non-small Cell Lung Cancer, Renal Cell Cancer, Colorectal Cancer
- Trial name
- NCT01507740
- Testing
- Avastin, Suntent, Nexavar
- Where
- Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Insulin Resistance
Intramyocellular Fatty Acid Trafficking in Insulin Resistance States - Effects of Intestinal Delivery of Lipids
Muscle insulin resistance is a hallmark of upper body obesity (UBO) and Type 2 diabetes (T2DM). It is unknown whether muscle free fatty acid (FFA) availability or intramyocellular fatty acid trafficking is responsible for muscle…
- Trial name
- NCT03818178
- Testing
- Intralipid, Palm Oil Emulsion, Saline
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Elderly, Probiotics
Effect of Multi-species Probiotic HOWARU® Restore, on Gut Microbiota of Elderly
The study is randomized, double-blinded and placebo-controlled with a duration of 24 weeks. Following randomization, healthy elderly are randomized into two groups receiving probiotics or placebo.
- Conditions
- Elderly, Probiotics, Clostridium Difficile, Gut Microbiota
- Trial name
- NCT02207140
- Testing
- HOWARU Restore
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Gabriella C. van Zanten
Gastrointestinal Disease, Colorectal Cancer
Randomized Controlled Study Comparing Colon Evaluation With The Pure-Vu System To A Standard Colonoscopy In Patients Who Are High Risk For Inadequate Bowel Preparation
The primary objective of this multi-center, prospective, randomized controlled trial is to evaluate the bowel cleansing after Pure-Vu use in outpatient subjects at high risk for inadequate colon preparation as compare to standard…
- Trial name
- RESCue (NCT04285008)
- Testing
- Pure-Vu System
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Motus GI Medical Technologies Ltd
Microbial Colonization
Analysis of Urinary, Vaginal and Intestinal Microbiota in Patients With Neurogenic Bladder
The neurogenic bladder and bowel are two pathological conditions occurring when damaged innervation results in functional alteration of both the bladder and the bowel with a clinical presentation that can vary from retention to…
- Trial name
- NCT06093035
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Chronic Pancreatitis
Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis (EUS-CPN) for Chronic Pancreatitis
Physicians need a tracking system for specific treatment modalities, and data to determine the impact of endoscopic ultrasound pain management for patients with chronic pancreatitis.
- Trial name
- CPN (NCT04403074)
- Testing
- Celiac Plexus Neurolysis
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Indiana University
Photoaging
Effects of Dietary Soy Protein on Facial Wrinkles in Postmenopausal Women
Soy and soy-derived products are the primary dietary sources of isoflavones, particularly daidzein and genistein, for humans. Isoflavones are noted to have several effects on the skin including proliferation of keratinocytes…
- Trial name
- NCT04871750
- Testing
- Soy protein, Casein protein
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Intestinal Permeability, Inflammation
Induction of Gut Permeability by an Oral Vaccine
This study evaluates the effect of an oral typhoid vaccine on disruption of the intestinal barrier and response of the immune system.
- Conditions
- Intestinal Permeability, Inflammation, Vaccine, Typhoid Fever
- Trial name
- NCT04083950
- Testing
- Vivotif Typhoid Oral Vaccine, Aspirin (Positive Control)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Lung Neoplasms, Neoplasm Metastasis
Mediastinal Lymph Node Dissection in Conjunction With Pulmonary Metastasectomy From Colorectal Cancer
To study whether or not total mediastinal lymph node dissection in conjunction with pulmonary metastasectomy from colorectal cancer is associated with improved survival compared to pulmonary metastasectomy only.
- Conditions
- Lung Neoplasms, Neoplasm Metastasis, Colorectal Cancer
- Trial name
- NCT03113318
- Testing
- Total mediastinal lymph node dissection and pulmonary metastasectomy, Only pulmonary metastasectomy
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Gestational Diabetes Mellitus in Childbirth, Neurodevelopmental Disorders
Early Biomarkers of Neurodevelopment in Offspring of Diabetic Mothers
The prospective multicenter study GD-Brain provides a better knowledge on the basis of neurological impairment in children born to mothers with gestational diabetes (GDM).
- Trial name
- GD-BRAIN (NCT03032991)
- Where
- Spain
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Poliomyelitis
Safety and Immunogenicity of 1 or 2 Doses of IPV in Latin American Infants Primed With Bivalent OPV Vaccine
This study is a Phase IV, open, randomized, multi-center, controlled vaccine trial conducted in healthy Latin American infants, utilizing one or two supplemental doses of IPV in children previously vaccinated with 3 doses of…
- Trial name
- NCT01831050
- Testing
- Bivalent Oral Polio Vaccine (bOPV), Trivalent Oral Polio Vaccine (tOPV), Monovalent Oral Polio Vaccine Type 2 (mOPV2)
- Where
- 4 sites in Colombia, Dominican Republic and 2 more
- Volunteers
- 1,420 people, healthy volunteers welcome
- Sponsor
- Fidec Corporation
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