Clinical trials: Intestine
Short Bowel Syndrome, Intestinal Failure
Level of Deprivation Assessment in a Population of Short-bowel Syndrome Patients With Intestinal Failure
The association between social deprivation and chronic disease is regularly examined but there are no data available on patients with intestinal failure due to short bowel syndrome (SBS-IF).
- Conditions
- Short Bowel Syndrome, Intestinal Failure, Deprivation, Psychosocial
- Trial name
- PRECAR-SGC (NCT06391762)
- Where
- France
- Volunteers
- 92 people
- Sponsor
- Central Hospital, Nancy, France
Overall Survival, Postoperative Complications
Clinical Value of Left Colic Artery in Laparoscopic Radical Rectectomy
Colorectal cancer is one of the most common tumors in Asia. According to the recent research, surgical procedure could provide more treatment benefit in rectal cancer.
- Trial name
- NCT03349788
- Testing
- LCA-nP, LCA-P
- Where
- China
- Volunteers
- 354 people
- Sponsor
- Shanghai Minimally Invasive Surgery Center
Ulcerative Colitis
An Investigation of Oral BT051 in Subjects With Moderately to Severely Active Ulcerative Colitis (UC)
This is a randomised, double-blind, placebo-controlled study to assess the safety and tolerability of multiple ascending doses of BT051 in subjects with moderately to severely active ulcerative colitis.
- Trial name
- SCOUT (NCT05084261)
- Testing
- BT051 200 mg, BT051 800 mg, BT051 3200 mg
- Where
- 6 sites in United States, Georgia and 2 more
- Volunteers
- 24 people
- Sponsor
- Adiso Therapeutics
Common Variable Immunodeficiency, Vascular Diseases
Composition and Function of Gut Microbiota in Porto-sinusoidal Vascular Disease Associated With Variable Common Immunodeficiency
This aim of this study is the evaluation of the gut microbiota imbalance occurrence and its characterization in patients with common variable immunodeficiency associated to an enteropathy with or without porto-sinusoidal vascular…
- Trial name
- MI-MVPS (NCT05481554)
- Testing
- Stool sample
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bowel Cleansing for Colonoscopy
Optimal Bowel Cleansing Trial
Comparison between large volume and osmotic agent lavage for optimal colonoscopy bowel cleansing, randomizing adult outpatients by invitation letter
- Trial name
- NCT01624454
- Testing
- Laxabon, CitraFleet
- Where
- 2 sites in Norway
- Volunteers
- 380 people
- Sponsor
- Helse Stavanger HF
Ulcerative Colitis (UC), Inflammatory Bowel Disease
Fecal Microbiota Transplantation for Ulcerative Colitis Using Dai and Han Donors
This study is a randomized clinical trial evaluating fecal microbiota transplantation (FMT) for ulcerative colitis (UC) using healthy donors from two ethnic groups in Yunnan, China.
- Trial name
- NCT07814456
- Testing
- Fecal Microbiota Transplantation (FMT)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital of Kunming Medical University
Crohn Disease, Ulcerative Colitis
Digital Behavioral Interventions in Inflammatory Bowel Disease
Given the bidirectionality between psychological distress and disease activity in inflammatory bowel disease (IBD), whereby increased psychological distress exacerbates disease activity and vice versa, psychosocial aspects of IBD…
- Conditions
- Crohn Disease, Ulcerative Colitis, Inflammatory Bowel Diseases, Stress, Psychological
- Trial name
- NCT04861597
- Testing
- Internet based cognitive behavioral therapy, Digital mood tracking
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Montefiore Medical Center
Healthy
Provitamin A Absorption and Conversion With Avocados
Vitamin A is necessary in the human diet. The form of vitamin A found in fruits and vegetables is not "active" and must be converted to the active form in the human body.
- Trial name
- NCT01432210
- Testing
- Post-prandial Feeding Study
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Appendicitis
The Circulating Fibrocyte - a Novel and Accurate Biomarker in Diagnosing Acute Appendicitis in Adults
Accurate diagnostic biomarkers for acute appendicitis (AA) are lacking. Circulating fibrocytes (CFs) are increased in inflammatory states. It is not known whether they are altered in appendicitis.
- Trial name
- NCT03988660
- Testing
- Circulating fibrocytes
- Where
- Ireland
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University Hospital of Limerick
Colonic Diverticulosis
Mesalamine for Uncomplicated Diverticular Disease: a Randomized, Double-blind, Placebo-controlled Study
The purpose of this study is to determine whether mesalamine is effective in the treatment of uncomplicated diverticular disease by reducing the pain.
- Trial name
- NCT01627262
- Testing
- Mesalamine
- Where
- Germany
- Volunteers
- 123 people
- Sponsor
- Dr. Falk Pharma GmbH
Crohn's Disease
Pediatric Crohn's Disease AdalImumab Level-based Optimization Treatment (PAILOT) Trial
Objectives: To examine the effect of drug level-based personalized treatment of adalimumab in children with Crohn's disease. Design: A prospective, randomized, open label study. Setting: Pediatric gastroenterology centers.
- Trial name
- NCT02256462
- Testing
- Adalimumab
- Where
- Israel
- Volunteers
- 82 people
- Sponsor
- Schneider Children's Medical Center, Israel
Aging, Undernutrition
Determination of In-vivo Plasma AA Appearance From Plant Protein Fibre Products
This study aims to assess the digestibility and efficacy of the study groups previously developed innovative plant-based protein and fibre products.
- Conditions
- Aging, Undernutrition, Appetite Loss, Age-Related Sarcopenia
- Trial name
- NCT05420142
- Testing
- Net peripheral AA appearance following ingestion of 3 selected PPF products compared to whey
- Where
- 2 sites in Ireland, Italy
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Bowel Preparation
A Prospective, Randomized, Investigator-blinded, Parallel, Multi-center, Phase 3 Trial
This is a prospective randomized study compared with active control arm.
- Trial name
- PROPELLER (NCT05670470)
- Testing
- CTP0303, Orafang Tab
- Where
- South Korea
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Taejoon Pharmaceutical Co., Ltd.
Ulcerative Colitis, Spondyloarthropathy
Real-world Effectiveness of Tofacitinib on Ulcerative Colitis Associated Spondyloarthropathy
Tofacitinib (TOFA) is a JAK inhibitor already used in rheumatology for the treatment of moderate-to-severe active rheumatoid arthritis and psoriatic arthritis in adult patients who have responded inadequately to, or who are…
- Trial name
- RETUCAS (NCT05431283)
- Testing
- Tofacitinib
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Italian Group for the study of Inflammatory Bowel Disease (IG-IBD)
Breast Cancer, Colon Cancer
Feasibility of an Evidence-based Walking Program in Cancer Pts 60+ During Chemotherapy
The study will look at conducting a medium-intense walking program called Walk With Ease with cancer patients age 60 and above who are starting chemotherapy treatment.
- Conditions
- Breast Cancer, Colon Cancer, Lung Cancer
- Trial name
- WWE (NCT01789983)
- Testing
- Walk With Ease Program, Collect Blood, GA and Other Survey Tools
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Gut Microbiota
To Investigate the Effect of Arabinogalactan on the Gut Microbiome in Adults
Dietary fiber is an important nutrient that supports gastrointestinal function, as well as the maintenance of blood glucose and cholesterol.
- Trial name
- NCT04351841
- Testing
- arabinogalactan, maltodextrin
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Biofortis, Merieux NutriSciences
Inflammatory Bowel Diseases, Ulcerative Colitis
Post-Marketing Use Of CT-P13 (Infliximab) For Standard Of Care Treatment Of Inflammatory Bowel Disease
This is a post-marketing observational study of patients with Inflammatory Bowel Disease (specifically, Crohn's disease or Ulcerative Colitis) who have been prescribed CT-P13 (infliximab) or Remicade (infliximab) for treatment.
- Conditions
- Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn's Disease
- Trial name
- CONNECT-IBD (NCT02539368)
- Testing
- CT-P13, Remicade
- Where
- 140 sites in Belgium, Czechia and 11 more
- Volunteers
- 2,565 people
- Sponsor
- Pfizer
Gut Microbiome, Cholesterol, LDL
Corn and Heart Health Study
The purpose of this study is to investigate the effects of 3 different corn flours: (1) whole grain corn flour, (2) 50% refined corn flour + 50% corn bran derived from whole corn meal, and (3) refined corn flour, on…
- Conditions
- Gut Microbiome, Cholesterol, LDL, Cholesterol, HDL
- Trial name
- CHS (NCT03967990)
- Testing
- Refined cornmeal flour, 50/50 refined cornmeal-bran mix, Whole grain cornmeal flour
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Hemorrhoids
Ligation and Hemorrhoidopexy Technique Versus Ligation of Hemorrhoidal Arteries Using Ultrasound for Hemorrhoids
The purpose of this study is to compare two techniques for treating hemorrhoids, the ligation and hemorrhoidopexy technique and the conventional ligation of hemorrhoidal arteries using ultrasound, in patients with non-complicated…
- Trial name
- NCT03298997
- Testing
- Ligation and Hemorrhoidopexy, Ultrasound Guided Ligation of Hemorrhoidal Arteries
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Larissa University Hospital
Inflammatory Bowel Diseases
Use of Mesenchymal Stem Cells in Inflammatory Bowel Disease
Scientists hypothesize that directly or parentally injecting Mesenchymal stem cells (MSCs) to affected areas will have a positive impact through reducing or abolishing intestinal inflammation in part via inhibition of neutrophil…
- Trial name
- NCT03299413
- Testing
- Wharton Jelly Mesenchymal stem cells
- Where
- Jordan
- Volunteers
- 20 people
- Sponsor
- Hanan Jafar
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