Clinical trials: Intestines
Abnormal Bowel Movement Such as Constipation, Diarrhea, Abdominal Pain
ID-JPL934 for Abnormal Bowel Movement
Probiotics, which are part of the human body, are microorganisms, which are known to have beneficial effects when consumed in a certain amount, and have the function of controlling intestinal flora and inhibiting inflammation.
- Trial name
- NCT03395626
- Testing
- ID-JPL934
- Where
- South Korea
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Hepatic Steatosis, Dietary Fructose Exposure
Dietary Fructose on Microbiota and Hepatosteatosis
The consumption of sugar-sweetened beverages (SSB) has increased steadily over the past decades, resulting in the dramatic increase of fructose intake as it is one of the main ingredients of artificial sweeteners.
- Trial name
- NCT04898621
- Testing
- 75g fructose solution, 150g fructose solution
- Where
- China
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Colorectal Neoplasms, Colonic Polyp
Effectiveness of Artificial Intelligence-Assisted Colonoscopy for Adenoma Detection in Routine Clinical Practice : a Prospective Multicenter Randomized Trial
This study is a multi-center, randomized controlled trial designed to evaluate whether an artificial intelligence (AI) system can assist endoscopists to improve the detection rate of colorectal adenomas and cancers during…
- Conditions
- Colorectal Neoplasms, Colonic Polyp, Adenoma, Colorectal Cancer
- Trial name
- AI-COLOADR (NCT07307547)
- Testing
- AI-Assisted Colonoscopy
- Where
- China
- Volunteers
- 3,300 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Inflammatory Bowel Disease, Crohn's Disease
Low Dose Naltrexone in Symptomatic Inflammatory Bowel Disease
The investigators will be looking at the efficacy of the use of once daily use of low dose naltrexone (4.5mg) in subjects with symptomatic inflammatory bowel disease.
- Conditions
- Inflammatory Bowel Disease, Crohn's Disease, Ulcerative Colitis
- Trial name
- NCT01810185
- Testing
- Low dose naltrexone
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Santa Barbara Cottage Hospital
Gut Microbiome, Neurocognitive Correlates of Eating Habits
Early Avocado Exposure on Development and the Gut Microbiome in American Hispanic Infants
The goal of this clinical trial is to learn if daily avocado intake can improve growth and brain and gut health in infants. The main questions it aims to answer are: Does daily eating of avocados change which microbes live in the…
- Conditions
- Gut Microbiome, Neurocognitive Correlates of Eating Habits, Infant Growth
- Trial name
- Guac & Grow (NCT06876935)
- Testing
- Daily avocado
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Lung Cancer, Colorectal Cancer
ProSight: A Multi-centre Interventional Study Evaluating MCED in Asymptomatic Population
This is a prospective, multi-centre interventional study evaluating the feasibility of blood-based multi-cancer early detection test in asymptomatic screening cohort.
- Conditions
- Lung Cancer, Colorectal Cancer, Liver Cancer, Grastic Cancer
- Trial name
- NCT06790355
- Testing
- multi-cancer early detection
- Where
- 4 sites in China
- Volunteers
- 2,527 people, healthy volunteers welcome
- Sponsor
- Shanghai Weihe Medical Laboratory Co., Ltd.
Alzheimer Disease
Gut Microbiota and Alzheimer's Diseases
The investigator will perform clinical studies to test a hypothesis that participants who have Alzheimer's disease will have different gut/oral microbiota profile as compared to the participants who do not have Alzheimer's…
- Trial name
- NCT03827733
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Achalasia, Gastric Fistula
Outcome Analysis of POEM and Endoluminal Therapies
Evaluation of current and newly developed endoluminal therapies in the management of Upper and Lower GI conditions.
- Conditions
- Achalasia, Gastric Fistula, Weight Gain After Primary Weight Loss Surgery, Marginal Ulcer
- Trial name
- NCT03123835
- Testing
- Endoscopic Intervention
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Growth, Infections
Effects of an Infant Formula and follow-on Formula Containing Bio-active Ingredients on Growth, Tolerance and Infections
In this clinical trial, the growth (weight for age), product tolerance (product intake, comfort) and infection-related symptoms of healthy infants consuming an IF and FOF containing bio-active ingredients will be evaluated and…
- Trial name
- NCT06137235
- Testing
- cows milk infant formula and follow-on formula with bioactive ingredients, standard cows milk infant formula and follow-on formula
- Where
- 3 sites in Greece
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- FrieslandCampina
Ulcerative Colitis
A Safety and Efficacy Study for Infliximab (Remicade) in Patients With Ulcerative Colitis
The purpose of this study is to evaluate the effectiveness and safety of infliximab (Remicade) in patients with Ulcerative Colitis.
- Trial name
- NCT00096655
- Testing
- Infliximab
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Centocor, Inc.
Insulin Resistance, Type 2 Diabetes Mellitus with Features of Insulin Resistance
NUTRITIONAL INTERVENTION STUDY to EVALUATE the EFFECT of ACHETA DOMESTICUS POWDER CONSUMPTION on GLUCOSE HOMEOSTASIS and INTESTINAL DYSBIOSIS in HEALTHY and PREDIABETIC POPULATION.
A nutritional intervention study is proposed to evaluate the association between the consumption of A. domesticus (insect protein) powder and the effect on insulin resistance and the microbiome, in order to generate personalized…
- Trial name
- DIBAN (NCT06622616)
- Testing
- EVALUATE THE EFFECT OF ACHETA DOMESTICUS POWDER CONSUMPTION ON GLUCOSE HOMEOSTASIS AND INTESTINAL DYSBIOSIS
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- María Isabel Espinosa
Intestinal Schistosomiasis
Schistosoma Mansoni Morbidity in Children Aged 1-5 Years
This study is about intestinal schistosomiasis, commonly known as bilharzia, in children aged 1-5 years along Lake Victoria shoreline.The children will be screened for S.
- Trial name
- NCT01901484
- Testing
- Praziquantel
- Where
- Uganda
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Makerere University
Colorectal Cancer Stage 0, Colorectal Cancer Stage I
Matrilysin Expression in Different Stages of Colorectal Tumors
Matrix metalloproteinases (MMPs) have been shown to be involved in cancer biology. Significant expression of MMP-7 (matrilysin) in colorectal cancer is mainly associated with metastatic disease even though it is expressed in most…
- Conditions
- Colorectal Cancer Stage 0, Colorectal Cancer Stage I, Colorectal Cancer Stage II, Colorectal Cancer Stage III
- Trial name
- MMP7 (NCT01570452)
- Testing
- colonic or colorectal resection
- Where
- Italy
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Fecal Microbiota Transplantation, Cesarean Section, Affecting Fetus or Newborn
Main Trial of the Cesarean Section and Intestinal Flora of the Newborn Study
In this study the investigators assess whether, in CS-delivered infants, the intestinal microbiome could be successfully and safely normalised by postnatal oral transfer of maternal fecal microbiome.
- Conditions
- Fecal Microbiota Transplantation, Cesarean Section, Affecting Fetus or Newborn, Intestinal Microbiome
- Trial name
- MT-SECFLOR (NCT04173208)
- Testing
- Fecal microbial transplant
- Where
- Finland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Zinc Deficiency, Mother and Child Malnutrition
Multi-Omic Profiling of a Zinc-Biofortified Maize Intervention in Guatemalan Mothers and Children
A trial evaluating the systemic and ecological impact of zinc-biofortified maize consumption on cellular zinc status, inflammatory biomarkers, and gut microbiota composition in a cohort of Guatemalan mothers and children.
- Trial name
- NCT07585318
- Testing
- F3 Biofortified Maize, Conventional Maize
- Where
- Guatemala
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition of Central America and Panama
Fecal Incontinence
Fecal Incontinence Subtypes in Women With Pelvic Floor Disorders
Fecal incontinence (FI) is clinically subtyped as urge FI and passive FI based on symptoms, however the pathophysiologic significance of this subtyping is not known.
- Trial name
- FIST (NCT02772874)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Irritable Bowel, Fibromyalgia
Psychiatric Disorders and Functional Somatic Disorders
The objectives of this study are: Firstly, to investigate the association between psychiatric disorders and functional somatic disorder (FSD).
- Conditions
- Irritable Bowel, Fibromyalgia, Chronic Fatigue Syndrome, Bodily Distress Syndrome
- Trial name
- NCT06006715
- Volunteers
- 7,493 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Adrenal Cortical Cancer, Brain Cancer
Spectroscopy With Surface Coils and Decoupling
The purpose of this study is to obtain chemical information from part of your body without a biopsy. This is done using a technique called magnetic resonance spectroscopy (MRS) which is similar to magnetic resonance imaging (MRI)…
- Conditions
- Adrenal Cortical Cancer, Brain Cancer, Breast Cancer, CNS Cancer
- Trial name
- NCT00581815
- Testing
- Proton-decoupled 31P MRS at 1.5T, 1H Spectroscopy at 1.5T and 3T
- Where
- United States
- Volunteers
- 582 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Colonoscopy Preparation
Efficacy and Safety of Bisacodyl and Lactulose as a Preparation for Colonoscopy
The purpose of the study is to evaluate the efficacy and safety of bisacodyl combined with escalating doses of lactulose to be used as a preparation for colonoscopy.
- Trial name
- NCT02123017
- Testing
- 90 grams of Crystalline Lactulose, 135 grams of Crystalline Lactulose, 180 grams of Crystalline Lactulose
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cumberland Pharmaceuticals
Breast Milk Collection, Human Milk/Breastfeeding
Human Milk and Its Effect on Infant's Metabolism and Infant Gut Microbiome
This protocol explains the MAINHEALTH cohort. The study examine the influence of maternal health parameters on human breast milk composition and integrates milk phenotype with infant metabolism and infant gut microbial content…
- Conditions
- Breast Milk Collection, Human Milk/Breastfeeding, Human Milk Microbiome, Infant Gut Microbiome
- Trial name
- MAINHEALTH (NCT05111990)
- Where
- Denmark
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
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