Clinical trials: Intolerance of Uncertainty
Anxiety
Pilot Study of an Extended CBT Group Intervention for Intolerance of Uncertainty
This study will examine the effect of cognitive-behavioral group psychotherapy, structured within the framework of ecological systems theory, on adults' intolerance of uncertainty.
- Trial name
- NCT07460479
- Testing
- Extended Cognitive-Behavioral Group Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Intolerance of Uncertainty; Anxiety
Computerized Cognitive Bias Intervention for Intolerance of Uncertainty
This investigation examines the efficacy of a brief, one-session computerized interpretation bias modification paradigm (CBM-I) in the reduction of intolerance of uncertainty.
- Trial name
- NCT02818296
- Testing
- Active IU CBM-I, Control CBM-I
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Florida State University
Self Efficacy, Anxiety
Fear of Cancer Recurrence Therapy (FORT): Turkish Cultural Adaptation and Implementation Project
This research consists of two phases. The aim of the first study is to adapt the group work module of Fear of Cancer Recurrence (FCR) for FCR in survivors of breast and ovarian cancer patients to the Turkish culture.
- Conditions
- Self Efficacy, Anxiety, Depression Not Otherwise Specified, Fear of Cancer Recurrence
- Trial name
- NCT06676228
- Testing
- Fear of cancer recurrence therapy (FORT), cognitive-behavioural therapy (CBT) group
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Maltepe University
High-risk Pregnancy
Affirmation-Based Information for Stress Reduction in High-Risk Pregnancy
This study examined whether providing affirmation-based information to high-risk pregnant women admitted to the obstetrics emergency department could reduce stress levels and intolerance of uncertainty.
- Trial name
- NCT07407322
- Testing
- Affirmation + Information Group
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Nilgun Avci
Generalized Anxiety Disorder, Emotional Disorder
Acceptability/Feasibility of IU Intervention
Anxiety disorders are prominent mental health burdens, affecting roughly 1 in 5 adults annually, and a third of individuals over the course of their life.
- Trial name
- CLUE (NCT05172427)
- Testing
- 14 days of EMI, Uncertainty reappraisal training
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Ohio University
Cognition of Osteopath
Measurement of the Intolerance to Uncertainty in Osteopaths
Clinical reasoning is a challenging, complex, multi-dimensional, essentially introspective and poorly understood cognitive process, as well as a crucial skill for osteopaths and health professionals.
- Trial name
- NCT06695806
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Institut des Hautes Etudes Osteopathiques de Nantes
Generalized Anxiety Disorder
A Single-Component CBT for GAD
Generalized Anxiety Disorder (GAD) is a chronic condition that is characterized by excessive and uncontrollable worry and anxiety. In Canada, 3 to 4% of the population suffer from GAD at any point in time.
- Trial name
- NCT02552108
- Testing
- Behavioural experiments for intolerance of uncertainty (BE-IU)
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universite du Quebec en Outaouais
Generalized Anxiety Disorder
Effects and Mechanisms of Change of Internet Delivered Cognitive Behavior Therapy for Generalized Anxiety Disorder
The goal of this clinical trial is to compare two psychological treatments for Generalized Anxiety Disorder. The main questions it aims to answer are: How well do these treatments work compared to earlier studies? Is one of the…
- Trial name
- ORIGAMI (NCT05849493)
- Testing
- Metacognitive Internet delivered Cognitive Behavior Therapy, Intolerance of uncertainty based Internet delivered Cognitive Behavior Therapy
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Karolinska Institutet
Mental Disorders, Mood Disorders
Group Transdiagnostic Cognitive Behavioural Therapy for Intolerance of Uncertainty Versus Applied Relaxation
Many people find uncertainty distressing, but for some, it may become overwhelming and drive persistent anxiety, worry, and avoidance.
- Conditions
- Mental Disorders, Mood Disorders, Anxiety Disorders, Generalized Anxiety Disorder
- Trial name
- OBSCURA (NCT07866794)
- Testing
- Group Transdiagnostic Cognitive Behavioural Therapy for Intolerance of Uncertainty (CBT-IU), Group Transdiagnostic Applied Relaxation (AR)
- Where
- United Kingdom
- Volunteers
- 135 people
- Sponsor
- Medical Research Council Cognition and Brain Sciences Unit
Psychiatric Nursing, Schizophrenia
The Effect of Psychoeducation Based on Uncertainty In Illness Theory On Schizophrenia Caregivers
The purpose of this study is to determine the effect of the psychoeducation program based on the Uncertainty in Illness Theory on intolerance to uncertainty, psychological well-being and coping styles of caregivers of…
- Trial name
- NCT04822051
- Testing
- The Uncertainty Management Psychoeducation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Hoarding Disorder
Imaginal Exposure for Hoarding Disorder
The present study will test a potential new treatment strategy, imaginal exposure, for hoarding disorder. Although cognitive behavioral therapy often reduces hoarding, some people do not want to start, or cannot handle, that…
- Trial name
- NCT03734705
- Testing
- Imaginal Exposure Writing, Neutral Writing
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Stanford University
Excessive Worry
CBT for Adolescents With Excessive Worry
This case series aims to test the feasibility and acceptability of streamlined cognitive behavioral therapy (CBT) for adolescents with excessive worry.
- Trial name
- BiPOro (NCT02978963)
- Testing
- Cognitive behavioral therapy
- Where
- Sweden
- Volunteers
- 12 people
- Sponsor
- Karolinska Institutet
Generalized Anxiety Disorder, Intolerance of Uncertainty
Group CBT for Intolerance of Uncertainty
Generalized anxiety disorder (GAD) is a debilitating condition involving excessive and uncontrollable worry and anxiety. Difficulty tolerating the uncertainties of life, known as intolerance of uncertainty (IU), has been shown to…
- Conditions
- Generalized Anxiety Disorder, Intolerance of Uncertainty, Anxiety
- Trial name
- NCT04512378
- Testing
- Behavioural Experiments for Intolerance of Uncertainty
- Where
- 2 sites in Canada
- Volunteers
- 6 people
- Sponsor
- University of Manitoba
Generalized Anxiety Disorder
Cognitive-behavioral Therapy for Generalized Anxiety Disorder in Primary Care
The feasibilty and preliminary comparative effectiveness of two methods of cognitive-behavioral therapy - metacognitive therapy and intolerance of uncertainty therapy - for primary care patients with generalized anxiety disorder…
- Trial name
- NCT03621371
- Testing
- Metacognitive therapy, Intolerance of uncertainty therapy
- Where
- Sweden
- Volunteers
- 64 people
- Sponsor
- Karolinska Institutet
Anxiety Disorders, Mindfulness
The Impact of Mindfulness-Based Psychoeducation on Perceived Stress, Intolerance of Uncertainty, and Cognitive Flexibility in Patients With Anxiety Disorders
Mindfulness-based interventions, which cultivate the capacity to remain present with difficult thoughts and emotions and to maintain psychological well-being in the face of such challenges, have been shown to facilitate positive…
- Conditions
- Anxiety Disorders, Mindfulness, Perceived Stress, Intolerance of Uncertainty
- Trial name
- Anxiety (NCT07299045)
- Testing
- Mindfulness-Based Psychoeducational Program
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Aydin Adnan Menderes University
Obsessive-Compulsive Disorder
Decision-making Impairments in OCD: An Integrated Behavioral Economics Model
The investigators are examining whether conditions of ambiguity during decision-making may prime intolerance of uncertainty beliefs (i.e., difficulties coping with ambiguity, unpredictability, and the future) and lead to impaired…
- Trial name
- NCT03420495
- Testing
- Decision-Making Tasks
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Intolerance to Uncertainty
The Effectiveness of Cognitive Bias Modification on Intolerance of Uncertainty
The current study aims to reduce the intolerance of uncertainty levels with an internet-based cognitive bias modification intervention in young adults with high levels of intolerance to uncertainty aged between 18 and 40.
- Trial name
- NCT06174311
- Testing
- Active Cognitive Bias Modification
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Izmir University of Economics
Generalized Anxiety Disorder
6-Session Treatment for Generalized Anxiety Disorder
Generalized Anxiety Disorder (GAD) is a chronic condition that is characterized by excessive and uncontrollable worry and anxiety. In Canada, 3 to 4% of the population suffer from GAD at any point in time.
- Trial name
- NCT03433625
- Testing
- Behavioural experiments for intolerance of uncertainty (BE-IU)
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universite du Quebec en Outaouais
Generalized Anxiety Disorder, Adolescent - Emotional Problem
Behavioural Experiments for Generalized Anxiety in Adolescents - Pilot Study
Generalized Anxiety Disorder (GAD) is a chronic condition characterized by excessive and uncontrollable worry and anxiety. In adolescents, this condition can seriously impact their development, academic performance, and social…
- Trial name
- EC-II-Ado-P (NCT06282133)
- Testing
- Behavioural Experiments for Intolerance of Uncertainty
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Universite du Quebec en Outaouais
Generalized Anxiety Disorder
Internet Delivered Cognitive Behavior Therapy Based on Intolerance of Uncertainty
The goal of this clinical is to pilot test an internet delivered cognitive behavior therapy (ICBT) based on intolerance of uncertainty (one of several existing specific cognitive models for how worry works) in treating…
- Trial name
- ORIGAMI (NCT05820568)
- Testing
- ICBT-IU
- Where
- Sweden
- Volunteers
- 22 people
- Sponsor
- Karolinska Institutet