Clinical trials: Intra-aortic Balloon Pump
Left Ventricular Assist Device, Heart Failure
Pulse Wave Analysis in Advanced Heart Failure
A comparison of pulse wave characteristics, as measured by peripheral tonometry, in pre and post Left Ventricular Assist Device (LVAD) patients.
- Conditions
- Left Ventricular Assist Device, Heart Failure, Intra-aortic Balloon Pump, LVAD Clot
- Trial name
- PWA-HF (NCT01642927)
- Where
- United States
- Sponsor
- University of Minnesota
Intra-aortic Balloon Pump
The Role of Angiographic Measurements and Anatomical Correlations in Intra-Aortic Balloon Pump (IABP) Size Selection
The goal of this study aim to accurately size the IABP size for patients. The main questions it aims to answer are: Are patients's height, jugular notch to transpyloric plane distance and distance from the carina to the upper…
- Trial name
- NCT06947174
- Where
- Thailand
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
High-Risk PCI
SAVE-PCI: NyokAssist™ Small-Bore VAD vs. IABP in Elective High-Risk PCI
SAVE-PCI is a prospective, multi-center, randomized controlled trial evaluating the safety and efficacy of NyokAssist™, a small-bore percutaneous ventricular assist device (pVAD), in comparison with intra-aortic balloon pump…
- Trial name
- NCT07010965
- Testing
- NyokAssist™, IABP Intra-aortic balloon pump
- Where
- 12 sites in China
- Volunteers
- 236 people
- Sponsor
- magAssist, Inc.
Acute Myocardial Infarction, Persisting Ischemia
Intra-aortic Balloon Pump in Extensive Myocardial Infarction With Persistent Ischemia
Patients presenting with large myocardial infarction and signs of persistent ischemia after successful percutaneous coronary intervention, have a poor prognosis with respect to outcome and development of heart failure in the…
- Conditions
- Acute Myocardial Infarction, Persisting Ischemia, No Reflow
- Trial name
- SEMPER FI (NCT02125526)
- Testing
- Intra-aortic balloon pump
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Lokien van Nunen
Cardiogenic Shock
HEROIC (Heparin Requirement in Counterpulsation)
Patients with intra-aortic balloon pumps (catheters placed in the groin connected to a pump which assists the heart by opening and closing a balloon in the aorta, thereby decreasing the work of the heart and improving blood flow…
- Trial name
- HEROIC (NCT00445211)
- Testing
- Heparin, Without Heparin
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Corewell Health East
Post-Cardiac Arrest Syndrome
The Effect of IABP Early Insertion on Mortality in Post Cardiac Arrest Patients With Acute Coronary Syndrome
The prevalence of cardiac arrests is still high worldwide. Despite the return of spontaneous circulation (ROSC), mortality and morbidity in post cardiac arrest patients is reported high.
- Trial name
- NCT03638609
- Testing
- Intra Aortic Balloon Pump
- Where
- Indonesia
- Volunteers
- 102 people
- Sponsor
- Universitas Indonesia
Ventricular Tachycardia
Percutaneous Hemodynamic Support With Impella 2.5 During Scar-related Ventricular Tachycardia Ablation
The purpose of this research study is to evaluate the safety and feasibility of the Impella 2.5 Circulatory Support System for use during mapping and ablation of ventricular tachycardia in the setting of Ventricular dysfunction.
- Trial name
- PERMIT1 (NCT01294267)
- Testing
- Circulatory Support System
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Vivek Reddy
Coronary Artery Disease, Coronary Artery Bypass Grafting
Perioperative Intra-Aortic Balloon Pump (IABP) in Coronary Artery Bypass Grafting (CABG) Operations in Patients With Severely Depressed Left Ventricular Function
Since its first introduction in humans in 1962, Intra-Aortic Balloon Pump (IABP) is now the most commonly used therapeutic option to support failing heart in cardiac surgery.
- Trial name
- NCT00881192
- Testing
- IABP
- Where
- 2 sites in Italy
- Volunteers
- 160 people
- Sponsor
- IRCCS Policlinico S. Donato
Coronary Artery Disease
Arterial Versus Venous Graft Recruitment by Intra-Aortic Balloon Pump
The aim of this study is to evaluate the different performance of arterial and venous graft with intra-aortic balloon pump support following coronary artery bypass.
- Trial name
- NCT00697723
- Testing
- Transit-time flowmetry
- Where
- Italy
- Volunteers
- 138 people
- Sponsor
- University Magna Graecia
Cardiogenic Shock
Study on Early Intra-aortic Balloon Pump Placement in Acute Decompensated Heart Failure Complicated by Cardiogenic Shock
The aim of the study is to demonstrate the superiority of early intra-aortic balloon pump implantation at admission over local clinical practice (pharmacological only) in acute decompensated heart failure patients with…
- Trial name
- Altshock-2 (NCT04369573)
- Testing
- Early intra-aortic balloon pump (IABP) implantation, Standard of care as vasoactive agent
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Niguarda Hospital
Heart Failure, Physical Therapy
Isolated Resistance Training and Neuromuscular Electrical Stimulation in Patients With Femoral Intra Aortic Balloon Pump.
The objective of this randomized clinical trial is to compare the effects of a standardized exercise program alone versus the same program combined with neuromuscular electrical stimulation in patients undergoing heart failure .
- Conditions
- Heart Failure, Physical Therapy, Neuromuscular Electrical Stimulation
- Trial name
- NCT06316349
- Testing
- Isolated Resistance Training Program, Neuromuscular electrical stimulation
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital
Elective Cardiac Surgery
Pleiades Safety and Feasibility Study
The "Pleiades" study is a non randomised, prospective, single center clinical trial that aims to evaluate the safety and the procedural feasibility of an innovative flow assist device (Pleioflow-RF) in adult patients undergoing…
- Trial name
- NCT05662501
- Testing
- Pleioflow-RF
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Pleioflow
Ischemic Cardiomyopathy, Heart Failure
Evaluation of Prophylactic Use of a Preoperative IABP in High-Risk Coronary Artery Bypass Graft Surgery
Background: The intra-aortic balloon balloon pump (IABP) has been used as a method of percutaneous circulatory assistance high surgical risk patients undergoing coronary artery bypass graft surgery (CABG); Although its…
- Trial name
- IABP-HR (NCT03857906)
- Testing
- Intra-Aortic Ballon Pump insertion
- Volunteers
- 129 people
- Sponsor
- CMN "20 de Noviembre"
Acute Anterior ST-Segment Elevation Myocardial Infarction
Prophylactic IABP in Delayed-Presentation Anterior STEMI
PROACTIVE-AMI is a prospective, multicenter, randomized, open-label trial with blinded endpoint adjudication evaluating whether prophylactic intra-aortic balloon counterpulsation (IABP) initiated before primary percutaneous…
- Trial name
- PROACTIVE-AMI (NCT07761455)
- Testing
- Intra-Aortic Balloon Pump, Primary Percutaneous Coronary Intervention
- Where
- 4 sites in China
- Volunteers
- 504 people
- Sponsor
- Qilu Hospital of Shandong University
Cardiogenic Shock
Early Left Ventricular unLoading by Impella vs Intra-aortic Balloon Pump
Over the past decade, VA-ECMO has become the main mechanical support for cardiogenic shock (CS) unresponsive to medical therapy.
- Trial name
- ELLIPSE1 (NCT06645990)
- Testing
- Impella, IABP
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Montpellier
Coronary Artery Disease, Heart Failure
PIONEER Trial:Hemodynamic Support With ECMO and IABP in Elective Complex High-risk PCI
To determine whether hemodynamic support combining VA-ECMO with IABP could mitigate the rates of Major Adverse Cardiovascular and Cerebrovascular Events (MACCEs), compared with IABP support alone, in patients undergoing elective…
- Trial name
- NCT04045873
- Testing
- extracorporeal membrane oxygenation
- Volunteers
- 306 people
- Sponsor
- Xijing Hospital
Coronary Artery Disease
Protect II, A Prospective, Multicenter Randomized Controlled Trial
The IMPELLA® 2.5 System will be superior to Intra Aortic Balloon Pump in preventing the composite rate of major adverse events during and after the PCI procedure.
- Trial name
- PROTECT II (NCT00562016)
- Testing
- IMPLELLA LP 2.5, IABP Intra-aortic balloon pump
- Where
- 50 sites in United States, Canada and 1 more
- Volunteers
- 452 people
- Sponsor
- Abiomed Inc.
ECMO
Early Intra-aortic Balloon Pump Use After Venoarterial Extracorporeal Membrane Oxygenation
The goal of this multicenter, randomized trial is to compare early early left ventricular unloading by Intra-aortic Balloon Pump (IABP) versus conventional approach in patients with cardiogenic shock (CS) undergoing venoarterial…
- Trial name
- EASE-ECMO (NCT06872021)
- Testing
- Early IABP use, Conventional approach
- Where
- China
- Volunteers
- 358 people
- Sponsor
- Beijing Anzhen Hospital
Shock, Cardiogenic, Heart Failure
Effects of Pyruvate in Patients With Cardiogenic Shock and Intra-aortic Balloon Counterpulsation
Pyruvate is an intermediate of energy metabolism and was shown to possess pronounced positive inotropic effects in vitro and in vivo without altering myocardial oxygen consumption.
- Conditions
- Shock, Cardiogenic, Heart Failure, Acute Myocardial Infarction
- Trial name
- NCT00604331
- Testing
- Pyruvate
- Where
- Germany
- Volunteers
- 8 people
- Sponsor
- Herzzentrum Goettingen
Acute Myocardial Infarction (AMI), Ventricular Septal Defects (VSD)
IABP for MI-VSD Patients in SCAI SHOCK Stage B
Ventricular septal defect (MI-VSD) is a serious mechanical complication of acute myocardial infarction, with an extremely high mortality.
- Trial name
- IABP-VISTAS (NCT07267884)
- Testing
- Insertion of IABP in SCAI SHOCK stage B
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Qilu Hospital of Shandong University