Clinical trials: Intra-operative Anesthesia, open to volunteers
Cesarean Section, Postoperative Nausea and Vomiting (PONV)
Restrictive vs Liberal Intraoperative Fluid Strategy and Postoperative Outcomes After Elective Cesarean Section
Spinal anesthesia for elective cesarean section is frequently associated with hemodynamic instability and postoperative complications such as postoperative nausea and vomiting (PONV) and delayed gastrointestinal recovery.
- Conditions
- Cesarean Section, Postoperative Nausea and Vomiting (PONV), Postdural Puncture Headache (PDPH), Postoperative Ileus
- Trial name
- NCT07440667
- Testing
- Restrictive intraoperative crystalloid fluid strategy (≤3 mL/kg/h), Liberal intraoperative crystalloid fluid strategy (>3 mL/kg/h)
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Nigde Omer Halisdemir University
Spine Surgery, Intraoperative Neurophysiological Monitoring
Low-Dose Rocuronium Maintenance During Spine Surgery With Intraoperative Neurophysiological Monitoring
This randomized controlled trial will compare two strategies for rocuronium use during general anesthesia for spine surgery with intraoperative neurophysiological monitoring.
- Conditions
- Spine Surgery, Intraoperative Neurophysiological Monitoring, Neuromuscular Blockade
- Trial name
- ROC-IONM (NCT07627750)
- Testing
- Low-Dose Rocuronium Maintenance, Rocuronium
- Where
- Vietnam
- Volunteers
- 62 people
- Sponsor
- Bach Mai Hospital
Anxiety, Anesthesia Awareness
Fear and Anxiety in Anesthesia-Naïve Patients Pre-operatively vs Post-operatively
The goal of this observational study is to understand how fear and anxiety felt by anesthesia-naive patients compares before versus after their scheduled surgery.
- Trial name
- NCT07559461
- Testing
- Survey using a questionnaire.
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stony Brook University
Neuromuscular Blockade Reversal Agent, Perioperative Complications
Sugammadex-Induced Clenching During Neuromuscular Blockade Reversal
Study Objective: This study aims to evaluate the incidence, severity, and risk factors of sugammadex-induced mouth clenching during neuromuscular blockade (NMB) reversal in adult surgical patients.
- Conditions
- Neuromuscular Blockade Reversal Agent, Perioperative Complications, Anesthesia, General, Sugammadex
- Trial name
- NCT06962007
- Testing
- Sugammadex 1 mg/kg Group, Sugammadex 2 mg/kg Group, Sugammadex 4 mg/kg Group
- Where
- South Korea
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Postoperative Cognitive Complications, Delirium
Prospective Observational Multimodal Neuromonitoring During High-Risk Adult Surgery
This is a prospective observational cohort study of adult patients undergoing high-risk surgery at UT Southwestern Medical Center.
- Conditions
- Postoperative Cognitive Complications, Delirium, Perioperative/Postoperative Complications, Brain Injuries
- Trial name
- NCT07577726
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Texas Southwestern Medical Center
Thyroid Surgeries, Intraoperative Analgesic Use
qCON/qNOX-Guided Anesthesia in Patients Undergoing Thyroidectomy Surgery
The aim of this study is to evaluate the effect of using the non-invasive Conox monitor on intraoperative opioid consumption. Additionally, the study aims to assess the impact of Conox monitoring on recovery time, postoperative…
- Conditions
- Thyroid Surgeries, Intraoperative Analgesic Use, Anesthesia Depth Monitoring
- Trial name
- NCT07445659
- Testing
- Connox EEG Monitoring, standard anesthesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kayseri City Hospital
Hypothermia, Accidental, Hypothermia; Anesthesia
Constructing a Risk Prediction Model for Intraoperative Hypothermia in Children Under General Anesthesia
Intraoperative hypothermia refers to a core body temperature below 36.0°C during surgery, which is common in surgical patients. Due to the fact that children's body temperature regulation function is not yet fully developed, they…
- Trial name
- NCT06892795
- Where
- China
- Volunteers
- 562 people
- Sponsor
- Harbin Medical University
Symptomatic Irreversible Pulpitis
Preoperative Dexamethasone Injection to Improve Local Anesthesia Success in Endodontic Treatment
This study aims to determine whether giving a single dose of 4mg dexamethasone before root canal treatment can reduce the amount of pain patients experience during the procedure .
- Trial name
- DILAS (NCT07699315)
- Testing
- dexamethasone, Saline (0.9% NaCl)
- Volunteers
- 60 people
- Sponsor
- Watim Medical & Dental College
Pain Relief After Arthroscopic Anterior Cruciate Ligament Reconstruction
Oral Melatonin With Intra Articular Analgesia on Pain After Arthroscopic Anterior Cruciate Ligament Reconstruction
Anterior Cruciate Ligament Reconstruction (ACLR) is a common orthopedic procedure that is accompanied by moderate to severe postoperative pain and is primarily performed on an outpatient basis.
- Trial name
- ACLR (NCT07096635)
- Testing
- Melatonin, Starch tablets
- Volunteers
- 50 people
- Sponsor
- Assiut University
Postoperative Acute Kidney Injury
Processed Electroencephalography-guided General Anesthesia and Outcomes in Major Abdominal Surgery
This study aims to evaluate whether the reduction in the amount of intraoperative norepinephrine required to prevent hypotension, facilitated by processed electroencephalography (pEEG) -guided general anesthesia, will lead to a…
- Trial name
- NCT06753409
- Testing
- Processed electroencephalography (pEEG) Guided General Anesthesia, Non-pEEG-Guided General Anesthesia (with blinded pEEG monitoring)
- Where
- Egypt
- Volunteers
- 162 people
- Sponsor
- Assiut University
Femoral Vein Diameter, Intraoperative Hypotension
Femoral Vein Diameter to Predict Intraoperative Hypotension in Geriatric Patients Undergoing Orthopedic Surgery Under Spinal Anesthesia
The study aims to assess whether the transverse diameter of the right common femoral vein (RCFV) in the inguinal region could reflect the degree of post-spinal hypotension during elective orthopedic surgery.
- Conditions
- Femoral Vein Diameter, Intraoperative Hypotension, Orthopedic Surgery, Spinal Anesthesia
- Trial name
- NCT07339475
- Testing
- Measurement of Femoral Vein Diameter
- Where
- Egypt
- Volunteers
- 43 people
- Sponsor
- Cairo University
Hypotension (MeSH: D007022)
Carotid Artery Blood Flow, Blood Pressure, and Cardiac Output During Anesthesia in Children Aged 0-5 Years
Blood pressure is routinely monitored during anesthesia in children, but blood pressure alone may not accurately reflect blood flow to vital organs.
- Trial name
- CARFLOW (NCT07847203)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Intraoperative Temperature Monitoring, Body Temperature
Agreement Among Three Methods of Intraoperative Core Temperature Monitoring: Nasopharyngeal Probe, TaiDoc TD-1261 Infrared Tympanic Thermometer, and 3M SpotOn™ Skin Sensor
Keeping a patient's body temperature normal during surgery is an important part of safe anesthetic care. When the body temperature drops below 36°C (called inadvertent perioperative hypothermia), patients face higher risks of…
- Trial name
- TEMP-AGREE (NCT07749209)
- Where
- Thailand
- Volunteers
- 270 people
- Sponsor
- Khon Kaen University
Anesthesia Awareness
Manual Versus Targer-controll Infusion in Reduction of Awareness and Dreaming
This study compares manual total intravenous anesthesia (TIVA) and target-controll infusion (TCI) in reduction of awareness and dreaming, and the haemodynamical stability during operation.
- Trial name
- NCT03476213
- Testing
- Group TCI, Group TIVA
- Where
- Czechia
- Volunteers
- 80 people
- Sponsor
- University Hospital Hradec Kralove
ıntraoperative Cerebral Oxygenation, Cerebral Oxygenation Monitoring
Comparison of the Effects of Desflurane-Remifentanyl and Propofol-Remifentanyl Anesthesia on Intraoperative Cerebral Oxygenation in Patients Undergoing Laparoscopic Cholecystectomy
Study Population: Patients undergoing elective laparoscopic cholecystectomy under general anesthesia will be included. Study Design: This is an observational study.
- Trial name
- NCT07517146
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Pain, Anesthesia
Impact of Intraoperative Non-invasive Analgesia Monitoring Using Nociception Level Index on Patient Management
This prospective randomised clinical trial aims to assess the impact of intraoperative nociception monitoring using NOL on anesthetic management during major abdominal surgery.
- Conditions
- Pain, Anesthesia, Perioperative Care
- Trial name
- NCT06804434
- Testing
- Lidocaine Intravenous Infusion, NOL
- Where
- Romania
- Volunteers
- 160 people
- Sponsor
- Osoian Cristiana
Intraoperative Awareness, Intraoperative Responsiveness During General Anesthesia
Evaluation of Intraoperative Awareness and Its Correlation With Processed EEG Biomarkers During Laparoscopic Surgery
This prospective observational cohort study aims to evaluate intraoperative responsiveness and possible intraoperative awareness in adult patients undergoing elective laparoscopic abdominal surgery under general anesthesia and to…
- Trial name
- NCT07831590
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people
- Sponsor
- Duzce University
Postoperative Pain, Knee Arthroscopy
Anterior Nerves of the Knee Block Versus Femoral Nerve Block for Knee Arthroscopy
Knee arthroscopy is one of the most common orthopedic procedures, and effective postoperative analgesia is essential for early mobilization and patient comfort.
- Conditions
- Postoperative Pain, Knee Arthroscopy, Analgesia
- Trial name
- ANK-FNB (NCT07910500)
- Testing
- Anterior Nerves of the Knee (ANK) Block, Femoral Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Van Training and Research Hospital
Craniosynostosis
Pleth Variability Index Monitoring in Pediatric Craniosynostosis Surgery
This prospective observational study aims to evaluate the role of pleth variability index (PVI) and perfusion index (PI) monitoring in intraoperative hemodynamic control among pediatric patients undergoing craniosynostosis…
- Trial name
- PVI-CRANIO (NCT07657598)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Muzaffer GENCER
Pain, Opioid Use
NOL-Guided vs Conventional Intraoperative Opioid Infusion on Outcomes in Geriatric Patients
The aim of this study is to compare the effects of conventional methods and goal-directed therapy guided by pain monitoring on total remifentanil dosage, wake-up time, and complications in geriatric patients undergoing lumbar…
- Conditions
- Pain, Opioid Use, Geriatric Anesthesia
- Trial name
- NCT07075003
- Testing
- nociceptive level
- Volunteers
- 80 people
- Sponsor
- Saglik Bilimleri Universitesi