Clinical trials: Intra-osseous
Peri Implantitis
BonyPid-500TM Bone Graft Substitute Study
This study is designed to assess the safety and effectiveness of BonyPid-500TM implantation for intrabony peri-implantitis defects.
- Trial name
- NCT02531100
- Testing
- BonyPid 500TM implantation concomitantly to SOC treatment, SOC treatment only
- Where
- 2 sites in Israel
- Volunteers
- 27 people
- Sponsor
- PolyPid Ltd.
Kidney Tubular Necrosis, Acute
Allogeneic Multipotent Stromal Cell Treatment for Acute Kidney Injury Following Cardiac Surgery
The purpose of this trial is to determine if the administration of allogeneic MSCs at defined doses is safe in patients who are at high risk of developing significant Acute Kidney Injury (AKI) after undergoing on-pump cardiac…
- Trial name
- NCT00733876
- Testing
- Multipotent Stromal Cells, Administration of MSC
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- AlloCure Inc.
Effect of Putty Form Bone Graft in Immediate Implant Placment
Evaluation of Hyaluronic Acid in Addition to Xenograft in Immediate Implant Placement Within Maxillary Esthetic Zone
Study design: The present study will be carried out on twenty patients selected from the department of Oral Medicine, Periodontology, Oral Diagnosis and Radiology, Faculty of Dentistry, Mansoura University for replacement of non…
- Trial name
- NCT06783517
- Testing
- cerabone, cerabone®plus
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Distal Humerus Fracture
Does Surgical-approach Affect Outcome After Fixation of Intra-articular Fractures of Distal Humerus?
observational study at tertiary care hospital and level 1 trauma centre aiming to evaluate the difference between two common surgical approaches to distal humerus fracture fixation.
- Trial name
- NCT03833414
- Testing
- triceps lifting and olecranon osteotomy approaches
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Bone Resorption, Diabetes
Application of Information-Motivation-Behavioral Model-based Continuity of Care on the Peri-implantitis Recovery in Diabetic Implant Overdenture Patients
The investigators recruited 32 diabetic IOD patients with a total of 110 problematic implants who had completed the treatment for peri-implantitis between January 2021 and March 2023 as research subjects.
- Trial name
- NCT06103799
- Testing
- IMB model-based continuity of care
- Where
- China
- Volunteers
- 32 people
- Sponsor
- The Dental Hospital of Zhejiang University School of Medicine
Dental Implant Failed
The Effect of Preoperative Antibiotics on Peri-implant Healing
Introduction: In order to minimize postoperative morbidity and failures of dental implant therapy, several antibiotic regimens have been proposed in the literature.
- Trial name
- NCT04280406
- Testing
- Azithromycin
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Peri-Implantitis, Alveolar Bone Loss
Non-Surgical Treatment of Peri-Implantitis With Ultrasonic Carbon Tip
As the frequency of dental implants increases, the incidence of complications and peri-implant diseases also increases. Early diagnosis and treatment of the disease is important to prevent consequences up to implant loss.
- Trial name
- NCT06514677
- Testing
- Ultrasonic Carbon Tip, Titanium Curette
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Acromegaly
Open Label Extension Study Evaluating Safety and Biological Activity of C2L-OCT-01 PR in Acromegalic Patients
The purpose of this study is to assess the safety profile of C2L-OCT-01 PR for up to an additional 96-week period in acromegalic patients who completed the C2L-OCT-01 PR-301 study.
- Trial name
- NCT00635765
- Testing
- C2L-OCT-01 PR 30 mg
- Where
- 6 sites in Belarus, Hungary and 4 more
- Volunteers
- 63 people
- Sponsor
- Ambrilia Biopharma, Inc.
Diabetic Neuropathies
Safety and Feasibility Study of Autologous Progenitor Cell Transplantation in Diabetic Neuropathy
Treatment of patients with diabetic neuropathy by intraarterial progenitor cell transplantation.
- Trial name
- NCT00282685
- Testing
- Intraarterial bone marrow progenitor cell transplantation
- Where
- Germany
- Volunteers
- 7 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Peri-Implantitis, Bone Loss in Jaw
An Evaluation of Salivary Oxidant and Antioxidant Levels in Peri-implant Health and Disease
Objectives: Inflammatory lesions develop in the tissues surrounding implants are referred to as peri-implant diseases. Oxidants, play a role in inflammatory lesions.
- Conditions
- Peri-Implantitis, Bone Loss in Jaw, Dental Implant Failed, Dental Implant Failure Nos
- Trial name
- NCT05724706
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Biruni University
Peri-implantitis, Dental Implants
The Effect of Systemic Factors on Peri-implant Health Status and Clinical Indices
This cross-sectional study evaluates the impact of systemic risk factors, including diabetes mellitus, smoking, cardiovascular disease, and osteoporosis, on peri-implant health status and clinical indices.
- Conditions
- Peri-implantitis, Dental Implants, Peri-implant Mucositis
- Trial name
- NCT07530211
- Testing
- Clinical and Radiographic Periodontal Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Inonu University
Aplastic Anemia
A Phase II Dose-escalation Study Characterizing the PK of Eltrombopag in Pediatric Patients With Previously Untreated or Relapsed Severe Aplastic Anemia or Recurrent Aplastic Anemia
This is a phase II, open label, multi-center, intra-patient dose escalation study to characterize the pharmacokinetics (PK) after oral administration of eltrombopag in combination with immunosuppressive therapy in pediatric…
- Trial name
- NCT03025698
- Testing
- Eltrombopag, hATG, CsA
- Where
- 20 sites in United States, Hong Kong and 4 more
- Volunteers
- 51 people
- Sponsor
- Novartis Pharmaceuticals
Partial Edentulism, Dental Implants
Comparison of Two Dental Implant Types and Placement Depths on Bone Around the Implant in Adults Missing Back Teeth
The goal of this clinical trial was to compare two ways of placing and restoring dental implants in adults missing one or more back teeth.
- Conditions
- Partial Edentulism, Dental Implants, Alveolar Bone Loss
- Trial name
- NCT07886762
- Testing
- issue-level implant placed at crestal level (Klockner Essential Cone), Bone-level implant placed 2 mm subcrestally with one-abutment-one-time protocol (Klockner Vega)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Markel Diéguez-Pereira
Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia
Intra-Osseous Co-Transplant of UCB and hMSC
This clinical trial studies intra-osseous donor umbilical cord blood and mesenchymal stromal cell co-transplant in treating patients with hematologic malignancies.
- Conditions
- Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, Myelodysplastic Syndromes, Myelofibrosis
- Trial name
- NCT02181478
- Testing
- cyclophosphamide, fludarabine phosphate, total-body irradiation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Case Comprehensive Cancer Center
Implant
Peri-implant Bone Behaviour Using Two Drilling Techniques in Posterior Maxilla
Two different drilling techniques in posterior maxilla immediate loading implant
- Trial name
- NCT06770231
- Testing
- Single drill system
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Spondylarthropathies
Seronegative Oligoarthritis of the Knee Study (SOKS)
The aim of this study is to establish the efficacy and duration of effect of intra-articular (IA) infliximab vs intravenous infliximab vs current standard care (IA steroid injections) in seronegative oligoarthritis.
- Trial name
- SOKS (NCT01216631)
- Testing
- methylprednisolone, Infliximab
- Where
- United Kingdom
- Volunteers
- 1 people
- Sponsor
- University of Leeds
Alveolar Bone Loss, Partially Edentulous Jaw
Impact of Hyaluronic Acid and Bone Graft on Peri-Implant Tissue
This randomized controlled clinical trial aims to evaluate the effect of hyaluronic acid (HA) and particulate bone graft on the peri-implant tissue phenotype in patients receiving dental implants.
- Conditions
- Alveolar Bone Loss, Partially Edentulous Jaw, Dental Implant
- Trial name
- NCT07665281
- Testing
- Dental Implants with Hyaluronic Acid, Dental Implants with Hyaluronic Acid and Particulate Bone Graft, Standard Dental Implants Placement only
- Where
- 2 sites in Iraq
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Articular Fracture
Volar Locking Plate Comparison With External Fixator
Local data has shown conflicting results regarding the outcomes of volar locking plates versus external fixators in distal intra-articular radius fractures.
- Trial name
- NCT07576075
- Testing
- Volar locking plates, External Fixator
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Muhammad Aamir Latif
Peri-implant Bone Loss, Peri-Implant Tissues
Ten Year Follow up of Convergent Profile Implants
The aim of the study is to evaluate the marginal bone level (MBL) and pink aesthetic score (PES) changes on the short, medium and long-term, on a retrospective cohort of patients who received at least one "biotype implant" (DEI…
- Trial name
- NCT07089407
- Testing
- Dental implant placement
- Where
- Italy
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
No Condition, Assessment of Healthy Volunteers
Usefulness of Intraosseous Anesthesia for Permanent Tooth Extraction Under GA in Pediatric Dental Treatment
The investigators are doing a study to see if a new way of giving local anesthesia during dental surgery can help children feel better after having a tooth removed under general anesthesia (when they are fully asleep).
- Trial name
- NCT07108439
- Testing
- Administration of intra-osseous local anesthesia before the extraction of a first permanent molar under general anesthesia
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- University Hospital, Ghent