Clinical trials: Intra-uterine Device
Contraception
Vaginal Misoprostol Before Intrauterine Contraceptive Device Insertion
the current study was conducted to assess efficacy of vaginal misoprostol before IUD insertion following previous insertion failure
- Trial name
- NCT03790371
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Pain, Anxiety
The Effect of Virtual Reality Application on Pain, Anxiety and Satisfaction of Patients
Today, common and easily accessible android-based smart devices capable of running virtual reality are used. The image is obtained using a combination of framed simple optical lenses that hold the phone at a fixed distance…
- Conditions
- Pain, Anxiety, Satisfaction
- Trial name
- NCT05760040
- Testing
- vırtual reality, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Marmara University
Contraception
Immediate Versus Delayed Intrauterine Device (IUD) Insertion Following First Trimester Suction Aspiration Procedures
The purpose of this multi-center clinical trial is to evaluate the safety and effectiveness of inserting an intrauterine device (IUD) immediately after a suction aspiration procedure compared to inserting the IUD 2-6 weeks after…
- Trial name
- PAIR (NCT00562276)
- Testing
- Immediate IUD insertion
- Where
- 3 sites in United States
- Volunteers
- 578 people
- Sponsor
- Oregon Health and Science University
Contraception
Effectiveness of Prolonged Use of IUD/Implant for Contraception
This study will evaluate LNG-IUD and Etonogestrel (ENG) Implant users who are willing to use their contraception beyond the end of the FDA-approved duration.
- Trial name
- EPIC (NCT02267616)
- Testing
- Etonogestrel Implant
- Where
- 2 sites in United States
- Volunteers
- 1,076 people, healthy volunteers welcome
- Sponsor
- Indiana University
IUD Not Visible
A RCT of Ultrasound Guided IUD Insertion
To determine the utility of ultrasound guided IUD insertion compared to the traditional blind insertion at an academic health institute where the skill level of the provider can vary greatly.
- Trial name
- NCT03493815
- Testing
- Transabdominal Ultrasound Guided IUD Insertion, Traditional Blind IUD Insertion
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Intrauterine Systems, Postpartum Immediate Contraception
Postpartum Immediate Contraception in Cesarean Deliveries-Comparison of Two Intrauterine Systems
To compare two intrauterine systems in order to avoid complications originating from short pregnancy interval and undesired pregnancies in the early postpartum period.
- Trial name
- NCT02941198
- Testing
- GyneFix, Cu T380 A
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Pain
Study of Pain Control With Hormonal IUS Insertion
This study aims to compare pain during insertion of the Skyla® IUS using a 100mm visual analog scale (VAS) among 92 young women aged 14 to 22 years randomized to receive a paracervical (n=46) block versus a sham paracervical…
- Trial name
- SOPHI (NCT02352714)
- Testing
- Paracervical Nerve Block
- Where
- 3 sites in United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Contraception
Immediate Postplacental IUD Insertion
The study will be a randomized clinical trial. Women with less than 10 prenatal visits and/or 2 or more no show visits who desire an Intrauterine Device (IUD) will be considered for enrollment.
- Trial name
- NCT02169869
- Testing
- Mirena, Paragard
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Oregon Health and Science University
Contraception Behavior
Cluster, Randomized Trial on Long Acting Reversible Contraception (LARC) Education and Training
The purpose of the study is to measure whether an education and training intervention for clinicians and contraceptive counselors on long-acting reversible contraception (LARC) will result in greater use of the methods among…
- Trial name
- LARC (NCT01360216)
- Testing
- LARC education and training
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- University of California, San Francisco
Evaluation of IUD Position Six Weeks After Insertion, Intrauterine Device Placement and Displacement
Transvaginal Three-Dimensional Ultrasound for Evaluation of Intrauterine Device Position Six Weeks After Insertion
This study aims to evaluate the position of intrauterine devices (IUDs) six weeks after insertion using transvaginal three-dimensional (3D) ultrasound.
- Trial name
- NCT07138248
- Testing
- 2D Transvaginal Ultrasound
- Where
- Egypt
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postpartum, Intrauterine Devices, Copper
Expulsion of Immediate Postplacental Copper Intrauterine Devices at Six Months: A Prospective Cohort Study
This is an observational study enrolling women who have had a copper intrauterine device placed immediately after childbirth. The study follows participants for 6 month in order to evaluate the primary outcome of IUD expulsion…
- Trial name
- PPIUD (NCT02706340)
- Testing
- No intervention - observational study only
- Where
- United States
- Volunteers
- 309 people
- Sponsor
- University of Pennsylvania
Heavy Menstrual Bleeding
Quality of Life in Premenopausal Women With Heavy Menstrual Bleeding
Heavy menstrual bleeding or menorrhagia, is a common problem on women's lives and can burden both patients and health care systems. HMB is defined as cyclic heavy vaginal bleeding.
- Trial name
- NCT03368898
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Contraception
Topical Lidocaine on the Cervix and Intra-Cervical Prior to Insertion of Intrauterine Devices
The hypothesis of this study is that topical cervical and intra-cervical lidocaine will decrease pain associated with the insertion of a Mirena® (levonorgestrel intrauterine device). 1.
- Trial name
- 10-053 (NCT01192490)
- Testing
- Lidocaine, Lubricant
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Contraception After Medical Abortion
Immediate Versus Later Insertion of IUD After Medical Termination of Pregnancy
The main objective of this study is to compare, in a randomised, controlled and prospective fashion, initiation of intrauterine contraception (IUC) at about immediate (0 to 3 days) versus 2 to 4 weeks post medical abortion with…
- Trial name
- NCT01755715
- Testing
- Immediate IUD insertion
- Where
- Finland
- Volunteers
- 264 people
- Sponsor
- Riina Korjamo
Blood Coagulation Disorders
The Effect of a Levonorgestrel-releasing Intrauterine Device (IUD) Versus a Copper Containing IUD on Risk of Blood Clots
This is a randomized controlled trial to assess the effect of a levonorgesterel-releasing intrauterine device (LNG IUD, Mirena®) versus a copper IUD (Paraguard®) on coagulation parameters known to be associated with risk of…
- Trial name
- NCT00584610
- Testing
- Levonorgestrel-containing IUD (Mirena®), Copper-containing IUD (Paraguard®)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Pain Due to Intrauterine Contraceptive Device
Pain Control for Intrauterine Device Placement Using Paracervical Block
Intrauterine device (IUD) placement can be painful for patients during and after the procedure. Fear of pain from IUD insertion can be a barrier to obtaining this highly effective long acting reversible contraception.
- Trial name
- NCT02219308
- Testing
- Paracervical Block (PCB)
- Where
- 2 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Infertility, Fertility Disorders
Live Birth Rate After Sperm Selection Using ZyMōt Multi (850µL) Device for Intra Uterine Insemination
This single centre interventional pilot randomized control study intends to compare two methods of sperm preparation for couples referred for Intra Uterine Insemination (IUI) procedure.
- Trial name
- FERTINSEM (NCT06144268)
- Testing
- ZyMōt Multi (850µL), Density Gradient Centrifugation
- Where
- Belgium
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Pain
Photobiomodulation on Pain Perception During the Insertion of the T 380 Copper Intrauterine Device (IUD)
Unplanned pregnancy affects up to 65% of women in some regions of Brazil, contributing to unsafe abortions and maternal mortality.
- Trial name
- NCT06984796
- Testing
- Photobiomodulation, Simulation of Photobiomodulation
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Contraception
Naproxen for Pain Control With Intrauterine Device Insertion
The purpose of this study is: 1. To evaluate whether 550 mg of naproxen sodium reduces pain scores with IUD insertion on a 0-10cm visual analogue scale compared to placebo (primary outcome). 2.
- Trial name
- NCT02388191
- Testing
- Naproxen sodium
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood League of Massachusetts
Adenomyosis
GyneFix IUD Plus LNG-IUS for Adenomyosis
Adenomyosis is a common gynecological condition that can cause menstrual pain, heavy menstrual bleeding, anemia, and reduced quality of life.
- Trial name
- GYNEFIX-AM (NCT07680985)
- Testing
- Indomethacin-GyneFix IUD Plus LNG-IUS, Ring IUD Plus LNG-IUS, LNG-IUS Alone
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Wenzhou People's Hospital