Clinical trials: Intracranial Arterial Aneurysm
Intracranial Aneurysm, Stroke, Ischemic
Neurovascular Product Surveillance Registry
Post market surveillance registry
- Trial name
- INSPIRE (NCT02988128)
- Testing
- Treatment for intracranial aneurysms, Treatment for Acute Ischemic Stroke
- Where
- 99 sites in Argentina, Australia and 22 more
- Volunteers
- 4,000 people
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Cerebral Aneurysm, Trigeminal Neuralgia
EEG Monitoring to Assess Emergence From Neuroanesthesia
A highly desired result in neuroanesthesia is a prompt, controlled emergence following a neurosurgical procedure. Considerable strides have been made in this direction with volatile anesthetic agents such as sevoflurane or…
- Trial name
- NCT00443807
- Testing
- On-line EEG monitoring during neurosurgery, EEGo vs BIS
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- University of Manitoba
Ischemic Stroke, Intracranial Aneurysm
Analysis of Selective Cerebrovascular Distribution With FDCT in the Angiosuite
The aim of this study is to evaluate the clinical feasibility of the angiographic Flat Detector CT perfusion imaging (6s PBV) technique.
- Conditions
- Ischemic Stroke, Intracranial Aneurysm, Intracranial Arterial Diseases, Cerebral Hypoxia
- Trial name
- NCT03916133
- Testing
- Intervention group
- Where
- Belgium
- Volunteers
- 127 people
- Sponsor
- University Hospital, Antwerp
Aneurysm, Intracranial, Natural History
The Natural Course of Unruptured Intracranial Aneurysms in a Chinese Cohort
This is a registry study of the natural course of unruptured intracranial aneurysms (UIA). In addition, the investigators will analyze the risk factors for the rupture of the UIA and their joint effect.
- Trial name
- NCT03117803
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Tang-Du Hospital
Intracranial Saccular Aneurysm, Either Rupture or Unruptured, Wide Neck Aneurysm
Solitaire Aneurysm Remodeling Registry
The objective of the registry is to evaluate the effectiveness and performance of the Solitaire Neurovascular Remodeling Device when used with embolic coils in the treatment of intracranial aneurysms.
- Trial name
- NCT04905303
- Where
- France
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Brain Injuries, Intracranial Aneurysm
Hypopituitarism Following Traumatic Brain Injury or Spontaneous Subarachnoidal Haemorrhages
The purpose of this study is to assess the prevalence and predictors of pituitary dysfunction, as well as secondary out-come in patients with traumatic brain injury or spontaneous subarachnoidal haemorrhages.
- Trial name
- NCT00435006
- Where
- Denmark
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Intracranial Aneurysm
LARGE Aneurysm Randomized Trial: Flow Diversion Versus Traditional Endovascular Coiling Therapy
In this study, patients with large anterior circulation IAs with neck and fundus morphologies amenable to either traditional endovascular treatments using coils or reconstruction with the flow diversion will be randomly assigned…
- Trial name
- LARGE (NCT01762137)
- Testing
- Flow Diversion, Coiling
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Medical University of South Carolina
Cerebral Aneurysm
Impact of Neurochecks on Sleep in Critically Ill Adults
Background: Following acute brain injury (ABI), patients are monitored in the intensive care unit (ICU) where providers rely on frequent neurological examinations ("neurochecks") to assess for neurodeterioration.
- Trial name
- NCT05864300
- Testing
- Neurocheck frequency
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Diego
Subarachnoid Hemorrhage, Cerebral Aneurysm
Amnesia After Surgery for Anterior Communicating Aneurysm： High Resolution Magnetic Resonance (MR) Imaging Findings
To clarify whether amnesia after treatment of anterior communicating aneurysm (ACoA)is related to infarcts caused by occlusion or damage of the perforating artery of the ACoA, we used 3.0-T 3D high resolution MR imaging to…
- Conditions
- Subarachnoid Hemorrhage, Cerebral Aneurysm, Amnesia
- Trial name
- NCT01919775
- Volunteers
- 14 people
- Sponsor
- Tohoku University
Cerebral Arteriovenous Malformation, Intracranial Arterial Diseases
Cerebral Arteriovenous Malformation With Aneurysm: Epidemiology, Clinical Features, and Prognosis
The study is a multicenter, prospective cohort study designed to assess the natural history, clinical safety and efficacy of various treatment strategies in patients with cerebral arteriovenous malformations (AVMs) and…
- Conditions
- Cerebral Arteriovenous Malformation, Intracranial Arterial Diseases, Intra Cerebral Hemorrhage, Intracranial Aneurysm
- Trial name
- NCT07353736
- Where
- China
- Volunteers
- 630 people
- Sponsor
- Duan Chuanzhi
Cerebral Aneurysm
Hydrogel Endovascular Aneurysm Treatment Trial
This research study is being done to test the effectiveness of a new generation FDA approved device for treating aneurysms compared to the current standard device for endovascular aneurysm treatment which is bare platinum coils.
- Trial name
- HEAT (NCT01407952)
- Testing
- HydroCoil Embolic System, Control (bare platinum coils)
- Where
- 44 sites in United States, Canada
- Volunteers
- 600 people
- Sponsor
- Northwestern University
Subarachnoid Hemorrhage, Cerebral Vasospasm
Effect of Intraventricular tPA Following Aneurysmal Subarachnoid Hemorrhage
This study will evaluate the hypothesis that the administration of intraventricular tPA reduces the rates of cerebral vasospasm and ventriculoperitoneal shunt-dependent hydrocephalus in patients with aneurysmal subarachnoid…
- Conditions
- Subarachnoid Hemorrhage, Cerebral Vasospasm, Cerebral Aneurysm, Hydrocephalus
- Trial name
- NCT01878136
- Testing
- Tissue Plasminogen Activator
- Where
- United States
- Sponsor
- Rush University Medical Center
Intracranial Aneurysm
Evaluation of Postoperative Cognitive Function, Anxiety, Depression and Quality of Life in Patients With Unruptured Intracranial Aneurysms
This prospective single-center cohort study aims to identify the incidence of cognitive dysfunction after unruptured aneurysm operation and explore the influencing factors.
- Trial name
- NCT03494608
- Volunteers
- 350 people
- Sponsor
- Xuanwu Hospital, Beijing
Myocardial Infarction, Ischemic Stroke
Understanding the Role of Autoimmune Disorders on the Initial Presentation of Cardiovascular Disease
Autoimmune diseases are diseases in which inappropriate immune responses that have the capability of harming host cells play an important role.
- Conditions
- Myocardial Infarction, Ischemic Stroke, Stroke, Subarachnoid Haemorrhage
- Trial name
- NCT02062021
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- University College, London
Aneurysmal Subarachnoid Hemorrhage, Vasospasm, Intracranial
Chemical and Mechanical Angioplasty for Vasospasm (SAVEBRAIN)
This is a monocentric randomized prospective trial comparing 2 different endovascular strategies of intracranial arterial angioplasty in case of refractory intracranial arterial vasospastic stenosis : chemical angioplasty…
- Conditions
- Aneurysmal Subarachnoid Hemorrhage, Vasospasm, Intracranial, Stenosis, Ruptured Cerebral Aneurysm
- Trial name
- SAVEBRAIN (NCT05268445)
- Testing
- Chemical and Mechanical Angioplasty for Refractory Intracranial Arterial Vasospastic Stenosis
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- Erasme University Hospital
Intracranial Aneurysm
Enterprise Stent Aneurysm Treatment (ESAT) Study - France
The purpose of this study is to evaluate the morbidity, mortality, and efficacy of use of the Enterprise(TM) stent for the treatment of (ruptured or non-ruptured) intracranial aneurysms.
- Trial name
- ESAT (NCT00879580)
- Where
- 14 sites in France
- Volunteers
- 133 people
- Sponsor
- Codman & Shurtleff
Intracranial Aneurysms
Canadian Study of the MicroVention Flow Re-Direction (FRED) Endoluminal Device Stent System in the Treatment of Intracranial Aneurysms
The study objective is to evaluate the safety and effectiveness of the MicroVention FRED System when used in the treatment of wide-necked intracranial aneurysms.
- Trial name
- CanFRED (NCT02309203)
- Testing
- FRED
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Flow Diverter
Clinical Safety and Efficacy of Flow-diverter in the Treatment of Intracranial Aneurysms
To collect the safety and effectiveness data of flow-di in the treatment of intracranial aneurysms in real-world clinical practice, verify its classification of treatment strategies for aneurysms of different locations and…
- Trial name
- NCT06943729
- Where
- China
- Volunteers
- 523 people
- Sponsor
- Huashan Hospital
Intracranial Aneurysms
Contrast-free Magnetic Resonance Angiography (MRA) at 3.0 T for Intracranial Aneurysm Detection
The Chinese Cerebral Aneurysms Survey is a continuing prospective study to evaluate the effectiveness of unenhanced, three-dimensional time-of-flight magnetic resonance angiography (3D-TOF-MRA) with volume rendering (VR) at 3-T…
- Trial name
- NCT01031147
- Testing
- Examination
- Where
- China
- Volunteers
- 350 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Intracranial Aneurysm
Cascade Clinical Data Collection Protocol
This study is a multi-center, single arm, open label, retrospective and prospective clinical data collection of CascadeTM, Non-Occlusive Remodeling Net, in adults with intracranial aneurysms, demonstrating the effectiveness and…
- Trial name
- NCT04760925
- Testing
- CascadeTM, Non-Occlusive Remodeling Net
- Where
- 7 sites in Bulgaria, Germany and 3 more
- Volunteers
- 112 people
- Sponsor
- Perflow Medical