Clinical trials: Intracranial Hemorrhage
Moyamoya Disease, Intracranial Hemorrhages
5T MRI and Metabolomics-Based Hemorrhage Risk Prediction in Moyamoya Disease
Intracranial hemorrhage is a leading cause of death and disability in patients with moyamoya disease (MMD), yet clinically available tools for predicting long-term hemorrhage risk are lacking.
- Conditions
- Moyamoya Disease, Intracranial Hemorrhages, Stroke
- Trial name
- NCT07781579
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Beijing Hospital
Acquired Brain Injury, Subarachnoid Hemorrhage
Cohort Study on the Effects of Aging in Acquired Brain Injury Patients
A prospective cohort study (questionnaires), with an embedded case control study (neuropsychological assessments) in which the data is gathered within a timeframe of 3 years.
- Conditions
- Acquired Brain Injury, Subarachnoid Hemorrhage, Traumatic Brain Injury, Cerebrovascular Accident
- Trial name
- BRAINReADAPT (NCT05499806)
- Where
- 2 sites in Netherlands
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Subarachnoid Hemorrhage, Delayed Cerebral Ischemia
MicroRNA Diagnostics in Subarachnoid Hemorrhage 2
The purpose of this study is to validate results from a related trial (NCT01791257) and to compare the profile of microRNA in blood from patients suffering subarachnoid hemorrhage with and without systemic complications.
- Conditions
- Subarachnoid Hemorrhage, Delayed Cerebral Ischemia, Acute Lung Injury, Cardiac Dysfunction
- Trial name
- NCT02320539
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cerebral Hemorrhage, Cerebral Ischemia
Study on Data Acquisition and Image Characteristics of Brain Multifrequency EIT in Healthy People and Patients With Brain Diseases
The goal of this observational study is to compare the differences in the features of cerebral multifrequency EIT(cMFEIT) images between healthy subjects and patients with brain diseases and to explore the possibility of applying…
- Conditions
- Cerebral Hemorrhage, Cerebral Ischemia, Cerebral Edema, Healthy
- Trial name
- NCT05796349
- Testing
- multifrequency EIT-based for detecting intracranial abnormalities
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Jieshi Ma
Myocardial Infarction, Ischemic Stroke
Understanding the Role of Autoimmune Disorders on the Initial Presentation of Cardiovascular Disease
Autoimmune diseases are diseases in which inappropriate immune responses that have the capability of harming host cells play an important role.
- Conditions
- Myocardial Infarction, Ischemic Stroke, Stroke, Subarachnoid Haemorrhage
- Trial name
- NCT02062021
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- University College, London
Abdominal Aortic Aneurysm, Coronary Heart Disease
Ethnicity and Onset of Cardiovascular Disease: A CALIBER Study
Specific cardiovascular diseases, such as stroke and heart attack, have been shown to vary by ethnic group. However, less is known about differences between ethnic groups and a wider range of cardiovascular diseases.
- Conditions
- Abdominal Aortic Aneurysm, Coronary Heart Disease, Sudden Cardiac Death, Intracerebral Haemorrhage
- Trial name
- NCT02176174
- Volunteers
- 1,068,318 people, healthy volunteers welcome
- Sponsor
- University College, London
Craniocerebral Trauma, Stroke
Timing Impact of Early vs. Late Cranioplasty on Hemicraniectomy Outcomes
This prospective, randomized study aims to comprehensively evaluate the impact of cranioplasty timing on postoperative complications and long-term functional outcomes following decompressive hemicraniectomy (DHC).
- Conditions
- Craniocerebral Trauma, Stroke, Intracranial Hemorrhages
- Trial name
- TIMELY (NCT06632587)
- Testing
- Early cranioplasty, Standard-of-care cranioplasty
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Intracerebral Hemorrhage, Brain Hemorrhage
Efficacy and Safety of Calculus Bovis Sativus (CBS) for Intracerebral Hemorrhage(CBSinICH)
The most common cause of death for Chinese patients is intracerebral hemorrhage(ICH), particularly cerebral infarction. It places a heavy burden on people, families, and society as a whole and poses considerable risks of death…
- Trial name
- NCT07080632
- Testing
- Calculus bovis sativus (CBS), Natural Calculus Bovis(NCB)
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Subarachnoid Hemorrhage
Stellate Ganglion Block as Adjuvant Therapy to ca Channel Blocker
Aim of work: To evaluate the effect of stellate ganglion block in prevention of cerebrovascular spasm in traumatic subarachnoid hemorrhage Primary outcome: Asses changes of cerebral blood flow velocity by Trans cranial Doppler.
- Trial name
- NCT04100824
- Testing
- stellate ganglion block by transcranial doppler, Nimodipine
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Brain Infarction, Ischemic Stroke
Searching for Explanations for Cryptogenic Stroke in the Young: Revealing the Etiology, Triggers, and Outcome
BACKGROUND: In industrialized countries a considerable and increasing proportion of strokes occur at younger ages. Stroke at young age causes marked disability at worst and thus long-standing socioeconomic consequences and…
- Conditions
- Brain Infarction, Ischemic Stroke, Thrombosis, Foramen Ovale, Patent
- Trial name
- SECRETO (NCT01934725)
- Where
- 19 sites in Estonia, Finland and 11 more
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- SECRETO Study Consortium
Hematoma, Subdural, Chronic
The Role of Meningeal Lymphatic Vessels in the Absorption of Chronic Subdural Hematoma and Its Injury Mechanism
Chronic subdural hematoma (CSDH) is a very common hemorrhagic disease of the nervous system, accounting for about 10% of hemorrhagic strokes.
- Trial name
- NCT05426889
- Testing
- subdural hematoma burr hole drainage, drug conservative treatment
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Traumatic Brain Injury, Cerebral Infarction
Characteristics of Blood- Brain Barrier Permeability in Neurological Patients
The main goal of the present study is to challenge the hypothesis that blood- brain barrier disruption following brain injury increases the risk for long-term disability, development of brain dysfunction, epileptic seizures and…
- Conditions
- Traumatic Brain Injury, Cerebral Infarction, Cerebral Hemorrhage
- Trial name
- NCT00419874
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Infant, Newborn, Infant, Small for Gestational Age
Vitamin E for Extremely Preterm Infants
The purpose of this pilot trial is to test the safety and efficacy of administering one dose of vitamin E, via a tube into the stomach, to extremely preterm infants (less than 27 weeks gestation and less than 1000 grams birth…
- Conditions
- Infant, Newborn, Infant, Small for Gestational Age, Infant, Very Low Birth Weight, Infant, Premature
- Trial name
- NCT01193270
- Testing
- Vitamin E
- Where
- 16 sites in United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- NICHD Neonatal Research Network
Quality of Life, Stroke, Acute
Cerebrovascular Disease: Quality of Life (CODE: QoL)
The goal of this observational study is to learn about quality of life, stress and caregiver burden in patients with stroke and their caregivers.
- Conditions
- Quality of Life, Stroke, Acute, Sexual Behavior, Stress
- Trial name
- CODE:QoL (NCT06443268)
- Testing
- questionnaire, hair samples, blood samples, clinical exam
- Where
- Switzerland
- Volunteers
- 680 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Chronic Subdural Hematoma
Randomized Controlled Trial Investigating Optimal Treatment for Chronic Subdural Hematoma
Setup of comparative trial The goal of this study is to determine whether one surgical treatment for chronic subdural hematoma is better than the other.
- Trial name
- NCT02655445
- Testing
- Mini-craniotomy, Twist Drill Craniostomy, Burr Hole Craniostomy
- Where
- Belgium
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Stroke
Guideline-recommended Basic Parameter Adherence in Neurocritical Care Patients
The aim of the planned study project is to assess the current situation regarding the treatment of patients with severe stroke at the neuro-critical care unit.
- Trial name
- NORMONICU (NCT06367543)
- Testing
- Time in therapeutic range of vital parameters
- Where
- Germany
- Volunteers
- 474 people, healthy volunteers welcome
- Sponsor
- University of Giessen
Intracerebral Hemorrhage
Use of Minocycline in Intracerebral Hemorrhage
To date, no neuroprotective drugs have demonstrated clinical efficacy in intracerebral hemorrhage (ICH). This study will use intravenous (IV) minocycline in ICH to evaluate for (1) safety/ tolerability and (2) evaluate for…
- Trial name
- NCT03040128
- Testing
- Minocycline, normal saline infusion
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Traumatic Brain Injury, Intracranial Hemorrhages
Usability Study of CEREBO® - A Novel Non-invasive Intracranial Bleed Detector
Traumatic Brain Injury (TBI) is the leading cause of death and disability across the globe. Time from injury to treatment is the most critical factor that determines the patient's recovery.
- Trial name
- NCT05340114
- Testing
- CEREBO®
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Bioscan Research Pvt. Ltd.
Diabetic Ketoacidosis, Heart Disease, Ischemic
Effectiveness of Music Intervention on Anxiety and Physiological Responses in Critical Ill Patient
Music intervention is a non-pharmacological and effective intervention that can alleviate anxiety and agitation in patients undergoing weaning.
- Conditions
- Diabetic Ketoacidosis, Heart Disease, Ischemic, Stroke, GastroIntestinal Bleeding
- Trial name
- NCT04977011
- Testing
- relaxing music
- Where
- Taiwan
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Min-Sheng General Hospital
Nervous System Diseases, Healthy Subjects
Functional Near-infrared Spectroscopy in Unconscious Patients
The study design is a single-center prospective pilot study. Hypothesis: Results of cerebral fNIRS examination in unconscious patients with severe hemorrhagic or ischemic stroke in the ICU are congruent with the results of SSEP…
- Trial name
- fNIRS (NCT04746820)
- Testing
- single-center prospective pilot study
- Where
- Switzerland
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Emanuela Keller