Clinical trials: Intracranial Hypertension
Meningitis, Meningitis/Encephalitis
Optic Nerve Ultrasound for Assessing Cerebral Inflammation and Intracranial Hypertension in Cerebral Pathologies
Timely detection of signs of raised intracranial pressure or persistent inflammation within the meninges can expedite therapeutic decisions improving the prognosis of patients with brain damage.
- Conditions
- Meningitis, Meningitis/Encephalitis, Stroke, Ultrasound
- Trial name
- EICON (NCT07332234)
- Testing
- Optic Nerve Sheath Diameter
- Where
- 2 sites in Romania
- Volunteers
- 200 people
- Sponsor
- Spitalul Clinic de Boli Infecțioase și tropicale "Dr. Victor Babeș"
Traumatic Brain Injury, Intracranial Hypertension
Optic Nerve Ultrasound in Severe Traumatic Injury
Prospective study of diagnostic accuracy of optic nerve sheath diameter measurement (index study) in traumatic brain injury with simultaneous invasive intracranial pressure monitoring as the reference standard.
- Trial name
- ONUS-TBI (NCT02618226)
- Testing
- Optic nerve ultrasound
- Where
- India
- Volunteers
- 117 people
- Sponsor
- University of Michigan
Idiopathic Intracranial Hypertension (IIH)
Eptinezumab for Chronic Headache in Idiopathic Intracranial Hypertension
The goal of this clinical trial is to learn if eptinezumab can reduce headache frequency and headache-related disability in adults with idiopathic intracranial hypertension (IIH) and chronic headache.
- Trial name
- PRIMA (NCT07645833)
- Testing
- Eptinezumab
- Volunteers
- 96 people
- Sponsor
- Rigmor Højland Jensen
Open-angle Glaucoma, Papilledema
aICP in Glaucoma and Papilledema
Glaucoma remains a disease with an unclear and complex underlying pathophysiology. Recently, researchers have emphasized not only intraocular pressure (IOP) or vascular dysregulation, but also translaminar pressure's (TPG) role…
- Trial name
- aICP Ophtha (NCT02410148)
- Testing
- Non-invasive ICP measurement (Vittamed 305)
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Kantonsspital Aarau
Idiopathic Intracranial Hypertension, Intracranial Pressure Increase
Prospective Ocular Imaging for Intracranial Pressure Evaluation
This is a prospectively recruiting, database development study collecting images and videos of the spontaneous venous pulsation at the back of people's eyes - this is a pulse one can see on examination of the back of the eye…
- Conditions
- Idiopathic Intracranial Hypertension, Intracranial Pressure Increase, Spontaneous Venous Pulsations
- Trial name
- POICCP (NCT06855342)
- Where
- United Kingdom
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Acute Brain Injury
Chest Physiotherapy Effects on Intracranial Pressure
The investigators will study the effects of a chest physiotherapy technique (rapid thoracic compression) on the intracranial pressure of individuals with acute cerebral injury and with need of intubated mechanical ventilation
- Trial name
- NCT03609866
- Testing
- rapid thoracic compression technique, inferior limb passive mobilization
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Santiago de Compostela
Intracranial Pressure Increase, Supraglottic Airway Device
Effect of Different Supralottic Airway Devicess on Optic Nerve Sheath Diameter
Direct laryngoscopy and tracheal intubation are associated with increases in intraocular pressure (IOP), intracranial pressure (ICP), heart rate (HR), and blood pressure.
- Conditions
- Intracranial Pressure Increase, Supraglottic Airway Device, Optic Nerve Sheath Diameter
- Trial name
- NCT05499754
- Testing
- pLMA: PROSEAL LARYNGEAL MASK, sLMA : SUPREMA LARYNGEAL MASK, I-jel =I-GEL
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Idiopathic Intracranial Hypertension
Assessment of ICP in Idiopathic Intracranial Hypertension Using Transocular Ultrasound and Transcranial Doppler
Idiopathic Intracranial Hypertension (IIH) is a rare disease, primarily affecting overweight females of child-bearing age. Patients suffer from increased intracranial pressure (ICP), typically resulting in headaches, visual…
- Trial name
- NCT04314128
- Testing
- TOS and TCD
- Where
- Denmark
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Intracranial Pressure Increase
Change of Optic Nerve Sheath Diameter After Deflation of Pneumatic Tourniquet
The purpose of this study is to evaluate the change of the optic nerve sheath diameter after deflation of pneumatic tourniquet.
- Trial name
- NCT03782077
- Testing
- Deflation of pneumatic tourniquet
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Asan Medical Center