Clinical trials: Intracranial Pressure Changes
Pregabalin, Optic Nerve Sheath Diameter Measurement
Effect of Pregabalin on Optic Nerve Sheath Diameter in Craniotomy Patients.
When patients undergo brain tumor removal surgery (craniotomy), the pressure inside the skull may increase, which can lead to brain swelling and slower recovery.
- Conditions
- Pregabalin, Optic Nerve Sheath Diameter Measurement, Intracranial Pressure Changes
- Trial name
- NCT07630753
- Testing
- Pregabalin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Intraocular Pressure, Intracranial Pressure
Intraocular Pressure and Optic Nerve Sheath Diameter Changes in Laparoscopic Cholecystectomies
Pneumoperitoneum created during laparoscopic surgeries has some effects on human physiology. Increased intraabdominal pressure results in increased intrathoracic pressure, and eventually may result in increased intracranial and…
- Conditions
- Intraocular Pressure, Intracranial Pressure, Pneumoperitoneum
- Trial name
- NCT03933254
- Testing
- Intraocular pressure measurement via ocular tonometry
- Sponsor
- Marmara University
Intracranial Pressure, Intracranial Pressure Changes
CoMind Early Feasibility Study
The purpose of this research, which has been determined as non-significant risk by the central IRB overseeing the study, is to obtain information to help further develop a machine (a medical device) to measure the pressure around…
- Conditions
- Intracranial Pressure, Intracranial Pressure Changes, Traumatic Brain Injury, Intracerebral Hemorrhage
- Trial name
- CoMind EFS (NCT06368648)
- Where
- 17 sites in United States
- Volunteers
- 581 people
- Sponsor
- CoMind Technologies Limited
Effect of Recruitment Maneuver on Intracranial Pressure
Evaluation of Intracranial Pressure During Mechanical Ventilation Recruitment Maneuver
Recruitment maneuver is used to reopen atelectasis alveoli. Positive airway pressure applied during the recruitment maneuver may increase intrathoracic pressure, resulting in hemodynamic instability, venous return disorders, and…
- Trial name
- NCT04935008
- Testing
- The recruitment maneuver
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Ondokuz Mayıs University
Brain Injuries, Subarachnoid Hemorrhage
A Study Comparing Modified Lund Concept and Cerebral Perfusion Pressure-targeted Therapy in Secondary Brain Ischaemia.
Secondary brain ischaemia (SBI) usually develops after aneurysmal subarachnoid haemorrhage (SAH) and severe traumatic brain injury (TBI).
- Trial name
- NCT01206283
- Testing
- Modified Lund concept, Cerebral perfusion pressure-targeted therapy
- Where
- Bosnia and Herzegovina
- Volunteers
- 60 people
- Sponsor
- University of Sarajevo
Traumatic Brain Injury (TBI) Patients
Chromatic Multifocal Pupillometer for Detection and Follow-up of Acute Head Injury
Traumatic Brain Injury (TBI) is a common injury in combat, terrorist attacks and sports such as football and hockey. Unnecessary delays in the diagnosis and treatment of brain damage in patients who can benefit from evacuation…
- Trial name
- NCT02030366
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Intracranial Pressure Change, Tracheostomy
The Effect of Percutaneous Dilatational Tracheostomy on Intracranial Pressure
Percutaneous dilatational tracheostomy (PDT) is a common bedside alternative to surgical tracheostomy in intensive care unit patients.
- Trial name
- NCT06779877
- Testing
- Percutaneous dilatational tracheostomy, The optic nerve sheath diameter measurement method by ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Akdeniz University
Intracranial Pressure Increase
Change of Optic Nerve Sheath Diameter After Deflation of Pneumatic Tourniquet
The purpose of this study is to evaluate the change of the optic nerve sheath diameter after deflation of pneumatic tourniquet.
- Trial name
- NCT03782077
- Testing
- Deflation of pneumatic tourniquet
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Asan Medical Center
INTRACRANIAL TUMOR, INTRACRANIAL PRESSURE
Evaluation of Postoperative Intracranial Pressure in Patients Undergoing Intracranial Tumor Surgery
Ultrasonography(USG)-guided optic nerve sheath diameter measurement and its correlation with brain computed tomography in the evaluation of intracranial pressure in patients who underwent intracranial brain tumor surgery.
- Conditions
- INTRACRANIAL TUMOR, INTRACRANIAL PRESSURE, OPTIC NERVE
- Trial name
- NCT06559566
- Testing
- USG, BCT
- Volunteers
- 50 people
- Sponsor
- Sezen Kumaş Solak
Optic Nerve Sheath Diameter, Intracranial Pressure Increase
Intraoperative Optic Nerve Sheath Diameter Changes After Laparoscopic Surgery
Laparoscopic surgery is a widely used alternative to open surgery; Advantages include reduced bleeding and pain intensity, shorter hospital stay, and improved cosmetic results.
- Trial name
- NCT06209034
- Testing
- Optic nerve sheath measurement
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Kocaeli University
Intracranial Pressure Change, Optic Nerve Diameter
VIMA vs TIVA and ONSD in Laparoscopic Cholecystectomy
This study compared two commonly used general anesthesia techniques in adults undergoing elective laparoscopic gallbladder surgery.
- Trial name
- NCT07786740
- Testing
- Propofol (Astra-Zeneca), Remifentanil, Sevofluorane
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bagcilar Training and Research Hospital
Anesthesia, Traumatic Brain Injury
The Effect of Mannitol Volume With Changes in Osmolarity in Traumatic Brain Injury
This observational study is designed to research the effect of mannitol volume administration with changes in osmolarity in patients with traumatic brain injury to guide the safe use of mannitol in these patients.
- Trial name
- NCT06846307
- Testing
- Mannitol
- Where
- Indonesia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universitas Diponegoro
Spinal Anesthesia, Intracranial Pressure Change
Effect of Spinal Needle Type on Optic Nerve Sheath Diameter
The optic nerve sheath is a continuation of the dura mater, extending along the subarachnoid space surrounding the optic nerve. Consequently, changes in intracranial pressure cause an augmentation or contraction in the diameter…
- Conditions
- Spinal Anesthesia, Intracranial Pressure Change, Optic Nerve Sheath Diameter, Orthopedic Surgery
- Trial name
- NCT06497634
- Testing
- 25 PP, 25 Q, 27 Q
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Bagcilar Training and Research Hospital
Intracerebral Hemorrhage, Intracerebral Haemorrhage
International Care Bundle Evaluation in Cerebral Hemorrhage Research
Spontaneous intracerebral haemorrhage (ICH) accounts for approximately 10-15% of all strokes but stands for 50% of stroke-related morbidity and mortality.
- Conditions
- Intracerebral Hemorrhage, Intracerebral Haemorrhage, Intraventricular Hemorrhage, Stroke
- Trial name
- I-CATCHER (NCT06429332)
- Testing
- Reversal of Oral anticoagulation within 30 minutes, Early intensive blood pressure lowering, Treatment of pyrexia
- Where
- 54 sites in United States, Australia and 6 more
- Volunteers
- 3,500 people
- Sponsor
- Region Skane
Eye Change, Idiopathic Intracranial Hypertension
ICP & Outflow Study
This study aims to investigate the relationship between intracranial pressure (ICP) and aqueous outflow (the flow of the eye's internal fluid out of the eye), in patients with increased intracranial pressure (idiopathic…
- Trial name
- NCT06436820
- Testing
- Lumbar puncture
- Volunteers
- 66 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Cerebral Venous Sinus Thrombosis, CSF Pressure Increased
Cerebral Venous Sinus Thrombosis: Re-exploration of Clinical Assessment Scales
This is a single-center, retrospective, open-label study. This study is planned to investigate the accuracy of mRS and NIHSS, comparing with the accuracy of CSF pressure and papilledema grade in assessing cerebral venous sinus…
- Conditions
- Cerebral Venous Sinus Thrombosis, CSF Pressure Increased, Papilledema
- Trial name
- NCT03273179
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Capital Medical University