Clinical trials: Intracranial Stenosis
Idiopathic Intracranial Hypertension
Biomarkers in the Etiology of Idiopathic Intracranial Hypertension
Idiopathic intracranial hypertension (IIH) is a condition characterized by an increase in intracranial pressure (ICP), papilledema with a risk of permanent visual loss, and severe headaches that profoundly affect quality of life.
- Trial name
- BEHIND (NCT06059703)
- Testing
- Blood punction, Central blood sampling, Intracranial pressure measurement
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Intracranial Atherosclerosis
Post Market Surveillance Study of the Wingspan Stent System
The primary objective of this study is to evaluate the rate of stroke and/or death in patients treated with the Wingspan Stent System, according to the Indications for Use, within 72 hours post procedure.
- Trial name
- WEAVE (NCT02034058)
- Testing
- Wingspan Stent System
- Where
- 26 sites in United States
- Volunteers
- 152 people
- Sponsor
- Stryker Neurovascular
Ischemic Stroke
Balloon Angioplasty for Minor Unstable Stroke With IntraCranial Atherosclerosis Stenosis (BAMUS-ICAS)
Intracranial atherosclerotic stenosis (ICAS) is a common cause of stroke, especially in East and South Asia, and is significantly associated with stroke recurrence and early neurological deterioration (END) despite aggressive…
- Trial name
- BAMUS-ICAS (NCT06763458)
- Testing
- Submaximal balloon angioplasty
- Where
- China
- Volunteers
- 100 people
- Sponsor
- General Hospital of Shenyang Military Region
Ischemic Heart Disease, Cardiac Arrest
Registry of Multicenter Brain-Heart Comorbidity in China
This study is a multi-center, prospective, registry study. This research was supported by the National Key Research and Development Program.
- Conditions
- Ischemic Heart Disease, Cardiac Arrest, Atrial Fibrillation, Heart Failure
- Trial name
- BHC-C (NCT05961748)
- Testing
- Multi-disciplinary assessment
- Where
- 14 sites in China
- Volunteers
- 100,000 people
- Sponsor
- Beijing Tiantan Hospital
Intracranial Artery Stenosis, Stent
Wingspan Stent System for Intracranial Artery Stenosis
The primary objective of this trial is to evaluate the safety and efficacy of Wingspan Stent System in \"real world\" patients with intracranial atherosclerotic stenosis.
- Conditions
- Intracranial Artery Stenosis, Stent, Endovascular Therapy
- Trial name
- NCT06618222
- Testing
- Wingspan stent system
- Where
- China
- Volunteers
- 43 people
- Sponsor
- The First People's Hospital of Changzhou
Aneurysmal Subarachnoid Hemorrhage, Vasospasm, Intracranial
Chemical and Mechanical Angioplasty for Vasospasm (SAVEBRAIN)
This is a monocentric randomized prospective trial comparing 2 different endovascular strategies of intracranial arterial angioplasty in case of refractory intracranial arterial vasospastic stenosis : chemical angioplasty…
- Conditions
- Aneurysmal Subarachnoid Hemorrhage, Vasospasm, Intracranial, Stenosis, Ruptured Cerebral Aneurysm
- Trial name
- SAVEBRAIN (NCT05268445)
- Testing
- Chemical and Mechanical Angioplasty for Refractory Intracranial Arterial Vasospastic Stenosis
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- Erasme University Hospital
Post-operative Craniotomy Patients, Carotid Endarterectomy and Carotid Artery Stenosis Patients
Effect of IV Acetaminophen on Patients in the Neurocritical Care Unit
To assess the efficacy of an intravenous nonnarcotic pain medication on controlling patient pain. To assess the effect of an intravenous nonnarcotic pain medication on patient sedation levels in neurocritically ill patients.
- Conditions
- Post-operative Craniotomy Patients, Carotid Endarterectomy and Carotid Artery Stenosis Patients, Post-op Spine Patients Admitted to the NCCU, Endovascular Patients Undergoing Intracranial Intervention
- Trial name
- NCT01948505
- Testing
- Intravenous acetaminophen
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- University of Utah
Large Vessel Occlusion, Intracranial Artery Occlusion With Cerebral Infarction
Endovascular Treatment of Acute Ischemic Stroke With Underlying Intracranial Artery Stenosis
The study is a prospective multicentre registry study. Patients admitted to 10 stroke centres nationwide from September 2022 to September 2025 with acute ischaemic stroke due to large vessel occlusion considering underlying ICAS…
- Conditions
- Large Vessel Occlusion, Intracranial Artery Occlusion With Cerebral Infarction, Endovascular Treatments, Acute Ischemic Stroke
- Trial name
- NCT06260969
- Testing
- balloon dilatation
- Where
- China
- Volunteers
- 470 people
- Sponsor
- Tianjin Huanhu Hospital
Intracranial Arterial Stenosis
Resuvastatin Treatment for Symptomatic Middle Cerebral Artery Stenosis Based on High-resolution Magnetic Resonance Imaging
1. It is a multicenter, open-label, sing arm study to evaluate the effects of treatment of Rosuvastatin 10-20mg in volume and morphology of atherosclerotic plague by reducing LDL-C level to or less than 70mg/dl. 2.
- Trial name
- REALM (NCT02041117)
- Testing
- Rosuvastatin
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Beijing Tiantan Hospital
Acute Stroke, Transient Ischemic Attack
Intensive Medical Therapy for High-risk Intracranial or Extracranial Atherosclerosis
Large-artery stenosis plays an important role in the occurrence of ischemic stroke. The primary purpose of this study is to evaluate the efficacy and safety of intensive antiplatelet therapy versus standard antiplatelet therapy…
- Trial name
- INSPIRES (NCT03635749)
- Testing
- Intensive antiplatelet, Standard antiplatelet, Immediate high-intensity statin
- Where
- 113 sites in China
- Volunteers
- 6,100 people
- Sponsor
- Beijing Tiantan Hospital